The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm
Identifieur interne : 001486 ( Istex/Curation ); précédent : 001485; suivant : 001487The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm
Auteurs : H. Razavi [États-Unis] ; I. Waked [Égypte] ; C. Sarrazin [Allemagne] ; R. P. Myers [Canada] ; R. Idilman [Turquie] ; F. Calinas [Portugal] ; W. Vogel [Autriche] ; M. C. Mendes Correa [Brésil] ; C. Hézode [France] ; P. Lázaro [Espagne] ; U. Akarca [Turquie] ; S. Aleman [Suède] ; Bal K [Turquie] ; T. Berg [Allemagne] ; F. Bihl [Suisse] ; M. Bilodeau [Canada] ; A. J. Blasco [Espagne] ; C. E. Brandão Mello [Brésil] ; P. Bruggmann [Suisse] ; M. Buti [Espagne] ; J. L. Calleja [Espagne] ; H. Cheinquer [Brésil] ; P. B. Christensen [Danemark] ; M. Clausen [Danemark] ; H. S. M. Coelho [Brésil] ; M. E. Cramp [Royaume-Uni] ; G. J. Dore [Australie] ; W. Doss [Égypte] ; A. S. Duberg [Suède] ; M. H. El-Sayed [Égypte] ; G. Ergör [Turquie] ; G. Esmat [Égypte] ; K. Falconer [Suède] ; J. Félix [Portugal] ; M. L. G. Ferraz [Brésil] ; P. R. Ferreira [Brésil] ; S. Frankova [République tchèque] ; J. García-Samaniego [Espagne] ; J. Gerstoft [Danemark] ; J. A. Giria [Portugal] ; F. L. Gonçales Jr [Brésil] ; E. Gower [États-Unis] ; M. Gschwantler [Autriche] ; M. Guimarães Pessôa [Brésil] ; S. J. Hindman [États-Unis] ; H. Hofer [Autriche] ; P. Husa [République tchèque] ; M. K Berg [Suède] ; K. D. E. Kaita [Canada] ; A. Kautz [Belgique] ; S. Kaymakoglu [Turquie] ; M. Krajden [Canada] ; H. Krarup [Danemark] ; W. Laleman [Belgique] ; D. Lavanchy [Suisse] ; R. T. Marinho [Portugal] ; P. Marotta [Canada] ; S. Mauss [Allemagne] ; C. Moreno [Belgique] ; K. Murphy [États-Unis] ; F. Negro [Suisse] ; V. Nemecek [République tchèque] ; N. Örmeci [Turquie] ; A. L. H. Vrehus [Danemark] ; J. Parkes [Royaume-Uni] ; K. Pasini [États-Unis] ; K. M. Peltekian [Canada] ; A. Ramji [Canada] ; N. Reis [Portugal] ; S. K. Roberts [Australie] ; W. M. Rosenberg [Royaume-Uni] ; F. Roudot-Thoraval [France] ; S. D. Ryder [Royaume-Uni] ; R. Sarmento-Castro [Portugal] ; D. Semela [Suisse] ; M. Sherman [Canada] ; G. E. Shiha [Égypte] ; W. Sievert [Australie] ; J. Sperl [République tchèque] ; P. St Rkel [Belgique] ; R. E. Stauber [Autriche] ; A. J. Thompson [Australie] ; P. Urbanek [République tchèque] ; P. Van Damme [Belgique] ; I. Van Thiel [Belgique, Allemagne] ; H. Van Vlierberghe [Belgique] ; D. Vandijck [Belgique] ; H. Wedemeyer [Allemagne] ; N. Weis [Danemark] ; J. Wiegand [Turquie] ; A. Yosry [Égypte] ; A. Zekry [Australie] ; M. Cornberg [Allemagne] ; B. Müllhaupt [Suisse] ; C. Estes [États-Unis]Source :
- Journal of Viral Hepatitis [ 1352-0504 ] ; 2014-05.
Abstract
The disease burden of hepatitis C virus (HCV) is expected to increase as the infected population ages. A modelling approach was used to estimate the total number of viremic infections, diagnosed, treated and new infections in 2013. In addition, the model was used to estimate the change in the total number of HCV infections, the disease progression and mortality in 2013–2030. Finally, expert panel consensus was used to capture current treatment practices in each country. Using today's treatment paradigm, the total number of HCV infections is projected to decline or remain flat in all countries studied. However, in the same time period, the number of individuals with late‐stage liver disease is projected to increase. This study concluded that the current treatment rate and efficacy are not sufficient to manage the disease burden of HCV. Thus, alternative strategies are required to keep the number of HCV individuals with advanced liver disease and liver‐related deaths from increasing.
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DOI: 10.1111/jvh.12248
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Razavi, Center for Disease Analysis, 901 Front Street, Suite 291, Louisville, CO 80027, USA.E‐mail:</mods:affiliation><wicri:noCountry code="subField">USA.E‐mail:</wicri:noCountry></affiliation><affiliation><mods:affiliation>E-mail: homie.razavi@centerforda.com</mods:affiliation><wicri:noCountry code="no comma">E-mail: homie.razavi@centerforda.com</wicri:noCountry></affiliation></author><author><name sortKey="Waked, I" sort="Waked, I" uniqKey="Waked I" first="I." last="Waked">I. Waked</name><affiliation wicri:level="1"><mods:affiliation>National Liver Institute, Menoufiya, Egypt</mods:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>National Liver Institute, Menoufiya</wicri:regionArea></affiliation></author><author><name sortKey="Sarrazin, C" sort="Sarrazin, C" uniqKey="Sarrazin C" first="C." last="Sarrazin">C. Sarrazin</name><affiliation wicri:level="1"><mods:affiliation>J.W. 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Bilodeau</name><affiliation wicri:level="1"><mods:affiliation>Liver Unit, Department of Medicine, Université de Montréal, QC, Montréal, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Liver Unit, Department of Medicine, Université de Montréal, QC, Montréal</wicri:regionArea></affiliation></author><author><name sortKey="Blasco, A J" sort="Blasco, A J" uniqKey="Blasco A" first="A. J." last="Blasco">A. J. Blasco</name><affiliation wicri:level="1"><mods:affiliation>Advanced Techniques in Health Services Research (TAISS), Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Advanced Techniques in Health Services Research (TAISS), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Brandao Mello, C E" sort="Brandao Mello, C E" uniqKey="Brandao Mello C" first="C. E." last="Brandão Mello">C. E. Brandão Mello</name><affiliation wicri:level="1"><mods:affiliation>Department of Gastroenterology, Federal University of the State of Rio de Janeiro, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Gastroenterology, Federal University of the State of Rio de Janeiro, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro</wicri:regionArea></affiliation></author><author><name sortKey="Bruggmann, P" sort="Bruggmann, P" uniqKey="Bruggmann P" first="P." last="Bruggmann">P. Bruggmann</name><affiliation wicri:level="1"><mods:affiliation>Arud Centres for Addiction Medicine, Zurich, Switzerland</mods:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Arud Centres for Addiction Medicine, Zurich</wicri:regionArea></affiliation></author><author><name sortKey="Buti, M" sort="Buti, M" uniqKey="Buti M" first="M." last="Buti">M. 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Cheinquer</name><affiliation wicri:level="1"><mods:affiliation>Hospital das Clínicas da Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Hospital das Clínicas da Universidade Federal do Rio Grande do Sul, Porto Alegre</wicri:regionArea></affiliation></author><author><name sortKey="Christensen, P B" sort="Christensen, P B" uniqKey="Christensen P" first="P. B." last="Christensen">P. B. Christensen</name><affiliation wicri:level="1"><mods:affiliation>Department of Infectious Diseases, Odense University Hospital, Odense, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Infectious Diseases, Odense University Hospital, Odense</wicri:regionArea></affiliation></author><author><name sortKey="Clausen, M" sort="Clausen, M" uniqKey="Clausen M" first="M." last="Clausen">M. Clausen</name><affiliation wicri:level="1"><mods:affiliation>Region Hospital Hovedstaden, Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Region Hospital Hovedstaden, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Coelho, H S M" sort="Coelho, H S M" uniqKey="Coelho H" first="H. S. M." last="Coelho">H. S. M. Coelho</name><affiliation wicri:level="1"><mods:affiliation>Department of Clinical Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Clinical Medicine, Federal University of Rio de Janeiro, Rio de Janeiro</wicri:regionArea></affiliation></author><author><name sortKey="Cramp, M E" sort="Cramp, M E" uniqKey="Cramp M" first="M. E." last="Cramp">M. E. Cramp</name><affiliation wicri:level="1"><mods:affiliation>Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth</wicri:regionArea></affiliation></author><author><name sortKey="Dore, G J" sort="Dore, G J" uniqKey="Dore G" first="G. J." last="Dore">G. J. Dore</name><affiliation wicri:level="1"><mods:affiliation>Kirby Institute, University of New South Wales, NSW, Sydney, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Kirby Institute, University of New South Wales, NSW, Sydney</wicri:regionArea></affiliation></author><author><name sortKey="Doss, W" sort="Doss, W" uniqKey="Doss W" first="W." last="Doss">W. Doss</name><affiliation wicri:level="1"><mods:affiliation>Cairo University, Cairo, Egypt</mods:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Cairo University, Cairo</wicri:regionArea></affiliation></author><author><name sortKey="Duberg, A S" sort="Duberg, A S" uniqKey="Duberg A" first="A. S." last="Duberg">A. S. Duberg</name><affiliation wicri:level="1"><mods:affiliation>Department of Infectious Diseases, Örebro University Hospital, Örebro, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Infectious Diseases, Örebro University Hospital, Örebro</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>School of Health and Medical Sciences, Örebro University, Örebro, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>School of Health and Medical Sciences, Örebro University, Örebro</wicri:regionArea></affiliation></author><author><name sortKey="El Ayed, M H" sort="El Ayed, M H" uniqKey="El Ayed M" first="M. H." last="El-Sayed">M. H. El-Sayed</name><affiliation wicri:level="1"><mods:affiliation>Ain Shams University, Cairo, Egypt</mods:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Ain Shams University, Cairo</wicri:regionArea></affiliation></author><author><name sortKey="Ergor, G" sort="Ergor, G" uniqKey="Ergor G" first="G." last="Ergör">G. Ergör</name><affiliation wicri:level="1"><mods:affiliation>Public Health and Epidemiology, Dokuz Eylul University, Izmir, Turkey</mods:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Public Health and Epidemiology, Dokuz Eylul University, Izmir</wicri:regionArea></affiliation></author><author><name sortKey="Esmat, G" sort="Esmat, G" uniqKey="Esmat G" first="G." last="Esmat">G. Esmat</name><affiliation wicri:level="1"><mods:affiliation>Cairo University, Cairo, Egypt</mods:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Cairo University, Cairo</wicri:regionArea></affiliation></author><author><name sortKey="Falconer, K" sort="Falconer, K" uniqKey="Falconer K" first="K." last="Falconer">K. Falconer</name><affiliation wicri:level="1"><mods:affiliation>Unit of Infectious Diseases, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Unit of Infectious Diseases, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Felix, J" sort="Felix, J" uniqKey="Felix J" first="J." last="Félix">J. Félix</name><affiliation wicri:level="1"><mods:affiliation>Exigo Consultores, Alhos Vedros, Portugal</mods:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Exigo Consultores, Alhos Vedros</wicri:regionArea></affiliation></author><author><name sortKey="Ferraz, M L G" sort="Ferraz, M L G" uniqKey="Ferraz M" first="M. L. G." last="Ferraz">M. L. G. Ferraz</name><affiliation wicri:level="1"><mods:affiliation>Division of Gastroenterology, Federal University of São Paulo, São Paulo, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Division of Gastroenterology, Federal University of São Paulo, São Paulo</wicri:regionArea></affiliation></author><author><name sortKey="Ferreira, P R" sort="Ferreira, P R" uniqKey="Ferreira P" first="P. R." last="Ferreira">P. R. Ferreira</name><affiliation wicri:level="1"><mods:affiliation>Division of Infectious Disease, Federal University of São Paulo, São Paulo, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Division of Infectious Disease, Federal University of São Paulo, São Paulo</wicri:regionArea></affiliation></author><author><name sortKey="Frankova, S" sort="Frankova, S" uniqKey="Frankova S" first="S." last="Frankova">S. Frankova</name><affiliation wicri:level="1"><mods:affiliation>Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic</mods:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague</wicri:regionArea></affiliation></author><author><name sortKey="Garcia Amaniego, J" sort="Garcia Amaniego, J" uniqKey="Garcia Amaniego J" first="J." last="García-Samaniego">J. García-Samaniego</name><affiliation wicri:level="1"><mods:affiliation>Hospital Carlos III, CIBERehd, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital Carlos III, CIBERehd, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Gerstoft, J" sort="Gerstoft, J" uniqKey="Gerstoft J" first="J." last="Gerstoft">J. Gerstoft</name><affiliation wicri:level="1"><mods:affiliation>University of Copenhagen, Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Giria, J A" sort="Giria, J A" uniqKey="Giria J" first="J. A." last="Giria">J. A. Giria</name><affiliation wicri:level="1"><mods:affiliation>Direcção‐Geral da Saúde, Lisboa, Portugal</mods:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Direcção‐Geral da Saúde, Lisboa</wicri:regionArea></affiliation></author><author><name sortKey="Goncales Jr, F L" sort="Goncales Jr, F L" uniqKey="Goncales Jr F" first="F. L." last="Gonçales Jr">F. L. Gonçales Jr</name><affiliation wicri:level="1"><mods:affiliation>Grupo de Estudo das Hepatites, Disciplina de Doenças Infecciosas, Departamento de Clínica Médica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, UNICAMP, São Paulo, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Grupo de Estudo das Hepatites, Disciplina de Doenças Infecciosas, Departamento de Clínica Médica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, UNICAMP, São Paulo</wicri:regionArea></affiliation></author><author><name sortKey="Gower, E" sort="Gower, E" uniqKey="Gower E" first="E." last="Gower">E. Gower</name><affiliation wicri:level="1"><mods:affiliation>Center for Disease Analysis, Colorado, Louisville, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Disease Analysis, Colorado, Louisville</wicri:regionArea></affiliation></author><author><name sortKey="Gschwantler, M" sort="Gschwantler, M" uniqKey="Gschwantler M" first="M." last="Gschwantler">M. Gschwantler</name><affiliation wicri:level="1"><mods:affiliation>Department of Internal Medicine IV, Wilhelminenspital, Vienna, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Internal Medicine IV, Wilhelminenspital, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Guimaraes Pessoa, M" sort="Guimaraes Pessoa, M" uniqKey="Guimaraes Pessoa M" first="M." last="Guimarães Pessôa">M. Guimarães Pessôa</name><affiliation wicri:level="1"><mods:affiliation>Division of Gastroenterology and Hepatology, University of São Paulo School of Medicine, São Paulo, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Division of Gastroenterology and Hepatology, University of São Paulo School of Medicine, São Paulo</wicri:regionArea></affiliation></author><author><name sortKey="Hindman, S J" sort="Hindman, S J" uniqKey="Hindman S" first="S. J." last="Hindman">S. J. Hindman</name><affiliation wicri:level="1"><mods:affiliation>Center for Disease Analysis, Colorado, Louisville, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Disease Analysis, Colorado, Louisville</wicri:regionArea></affiliation></author><author><name sortKey="Hofer, H" sort="Hofer, H" uniqKey="Hofer H" first="H." last="Hofer">H. Hofer</name><affiliation wicri:level="1"><mods:affiliation>Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Husa, P" sort="Husa, P" uniqKey="Husa P" first="P." last="Husa">P. Husa</name><affiliation wicri:level="1"><mods:affiliation>Clinic of Infectious Diseases of the University Hospital Brno, Masaryk University Brno, Brno, Czech Republic</mods:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Clinic of Infectious Diseases of the University Hospital Brno, Masaryk University Brno, Brno</wicri:regionArea></affiliation></author><author><name sortKey="K Berg, M" sort="K Berg, M" uniqKey="K Berg M" first="M." last="K Berg">M. K Berg</name><affiliation wicri:level="1"><mods:affiliation>Unit of Infectious Diseases, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Unit of Infectious Diseases, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Kaita, K D E" sort="Kaita, K D E" uniqKey="Kaita K" first="K. D. E." last="Kaita">K. D. E. Kaita</name><affiliation wicri:level="1"><mods:affiliation>Section of Hepatology, Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Section of Hepatology, Department of Internal Medicine, University of Manitoba, Winnipeg, MB</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Viral Hepatitis Investigative Unit, Health Sciences Centre, MB, Winnipeg, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Viral Hepatitis Investigative Unit, Health Sciences Centre, MB, Winnipeg</wicri:regionArea></affiliation></author><author><name sortKey="Kautz, A" sort="Kautz, A" uniqKey="Kautz A" first="A." last="Kautz">A. Kautz</name><affiliation wicri:level="1"><mods:affiliation>European Liver Patients Association, Sint‐Truiden, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>European Liver Patients Association, Sint‐Truiden</wicri:regionArea></affiliation></author><author><name sortKey="Kaymakoglu, S" sort="Kaymakoglu, S" uniqKey="Kaymakoglu S" first="S." last="Kaymakoglu">S. Kaymakoglu</name><affiliation wicri:level="1"><mods:affiliation>Gastroenterology, Istanbul University, Istanbul, Turkey</mods:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Gastroenterology, Istanbul University, Istanbul</wicri:regionArea></affiliation></author><author><name sortKey="Krajden, M" sort="Krajden, M" uniqKey="Krajden M" first="M." last="Krajden">M. Krajden</name><affiliation wicri:level="1"><mods:affiliation>British Columbia Centre for Disease Control, University of British Columbia, BC, Vancouver, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>British Columbia Centre for Disease Control, University of British Columbia, BC, Vancouver</wicri:regionArea></affiliation></author><author><name sortKey="Krarup, H" sort="Krarup, H" uniqKey="Krarup H" first="H." last="Krarup">H. Krarup</name><affiliation wicri:level="1"><mods:affiliation>Department of Medical Gastroenterology and Section of Molecular Diagnostics, Cinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Medical Gastroenterology and Section of Molecular Diagnostics, Cinical Biochemistry, Aalborg University Hospital, Aalborg</wicri:regionArea></affiliation></author><author><name sortKey="Laleman, W" sort="Laleman, W" uniqKey="Laleman W" first="W." last="Laleman">W. Laleman</name><affiliation wicri:level="1"><mods:affiliation>University Hospitals Leuven, KU Leuven, Leuven, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>University Hospitals Leuven, KU Leuven, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Lavanchy, D" sort="Lavanchy, D" uniqKey="Lavanchy D" first="D." last="Lavanchy">D. Lavanchy</name><affiliation wicri:level="1"><mods:affiliation>Independent Consultant, Denges, Switzerland</mods:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Independent Consultant, Denges</wicri:regionArea></affiliation></author><author><name sortKey="Marinho, R T" sort="Marinho, R T" uniqKey="Marinho R" first="R. T." last="Marinho">R. T. Marinho</name><affiliation wicri:level="1"><mods:affiliation>Gastroenterology Department, Centro Hospitalar de Lisboa Norte, Hospital Santa Maria, Lisboa, Portugal</mods:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Gastroenterology Department, Centro Hospitalar de Lisboa Norte, Hospital Santa Maria, Lisboa</wicri:regionArea></affiliation></author><author><name sortKey="Marotta, P" sort="Marotta, P" uniqKey="Marotta P" first="P." last="Marotta">P. Marotta</name><affiliation wicri:level="1"><mods:affiliation>Division of Gastroenterology, University of Western Ontario, ON, London, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Gastroenterology, University of Western Ontario, ON, London</wicri:regionArea></affiliation></author><author><name sortKey="Mauss, S" sort="Mauss, S" uniqKey="Mauss S" first="S." last="Mauss">S. Mauss</name><affiliation wicri:level="1"><mods:affiliation>Heinrich‐Heine University in Duesseldorf, Dusseldorf, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Heinrich‐Heine University in Duesseldorf, Dusseldorf</wicri:regionArea></affiliation></author><author><name sortKey="Moreno, C" sort="Moreno, C" uniqKey="Moreno C" first="C." last="Moreno">C. Moreno</name><affiliation wicri:level="1"><mods:affiliation>Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Erasme University Hospital, Université Libre de Bruxelles, Brussels</wicri:regionArea></affiliation></author><author><name sortKey="Murphy, K" sort="Murphy, K" uniqKey="Murphy K" first="K." last="Murphy">K. Murphy</name><affiliation wicri:level="1"><mods:affiliation>Center for Disease Analysis, Colorado, Louisville, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Disease Analysis, Colorado, Louisville</wicri:regionArea></affiliation></author><author><name sortKey="Negro, F" sort="Negro, F" uniqKey="Negro F" first="F." last="Negro">F. Negro</name><affiliation wicri:level="1"><mods:affiliation>Divisions of Gastroenterology and Hepatology and of Clinical Pathology, University Hospital, Genève, Switzerland</mods:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Divisions of Gastroenterology and Hepatology and of Clinical Pathology, University Hospital, Genève</wicri:regionArea></affiliation></author><author><name sortKey="Nemecek, V" sort="Nemecek, V" uniqKey="Nemecek V" first="V." last="Nemecek">V. Nemecek</name><affiliation wicri:level="1"><mods:affiliation>National Reference Laboratory for Hepatitis, National Institute of Public Health, Prague, Czech Republic</mods:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>National Reference Laboratory for Hepatitis, National Institute of Public Health, Prague</wicri:regionArea></affiliation></author><author><name sortKey="Ormeci, N" sort="Ormeci, N" uniqKey="Ormeci N" first="N." last="Örmeci">N. Örmeci</name><affiliation wicri:level="1"><mods:affiliation>Gastroenterology, Ankara University, Ankara, Turkey</mods:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Gastroenterology, Ankara University, Ankara</wicri:regionArea></affiliation></author><author><name sortKey=" Vrehus, A L H" sort=" Vrehus, A L H" uniqKey=" Vrehus A" first="A. L. H." last=" Vrehus">A. L. H. Vrehus</name><affiliation wicri:level="1"><mods:affiliation>Department of Infectious Diseases, Odense University Hospital, Odense, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Infectious Diseases, Odense University Hospital, Odense</wicri:regionArea></affiliation></author><author><name sortKey="Parkes, J" sort="Parkes, J" uniqKey="Parkes J" first="J." last="Parkes">J. Parkes</name><affiliation wicri:level="1"><mods:affiliation>University of Southhampton, Southhampton, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Southhampton, Southhampton</wicri:regionArea></affiliation></author><author><name sortKey="Pasini, K" sort="Pasini, K" uniqKey="Pasini K" first="K." last="Pasini">K. Pasini</name><affiliation wicri:level="1"><mods:affiliation>Center for Disease Analysis, Colorado, Louisville, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Disease Analysis, Colorado, Louisville</wicri:regionArea></affiliation></author><author><name sortKey="Peltekian, K M" sort="Peltekian, K M" uniqKey="Peltekian K" first="K. M." last="Peltekian">K. M. Peltekian</name><affiliation wicri:level="1"><mods:affiliation>Departments of Medicine and Surgery, Queen Elizabeth II Health Sciences Centre, Capital District Health Authority, Dalhousie University and Hepatology Services, NS, Halifax, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Departments of Medicine and Surgery, Queen Elizabeth II Health Sciences Centre, Capital District Health Authority, Dalhousie University and Hepatology Services, NS, Halifax</wicri:regionArea></affiliation></author><author><name sortKey="Ramji, A" sort="Ramji, A" uniqKey="Ramji A" first="A." last="Ramji">A. Ramji</name><affiliation wicri:level="1"><mods:affiliation>Department of Gastroenterology, University of British Columbia, BC, Vancouver, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Gastroenterology, University of British Columbia, BC, Vancouver</wicri:regionArea></affiliation></author><author><name sortKey="Reis, N" sort="Reis, N" uniqKey="Reis N" first="N." last="Reis">N. Reis</name><affiliation wicri:level="1"><mods:affiliation>Assembleia da República, Lisboa, Portugal</mods:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Assembleia da República, Lisboa</wicri:regionArea></affiliation></author><author><name sortKey="Roberts, S K" sort="Roberts, S K" uniqKey="Roberts S" first="S. K." last="Roberts">S. K. Roberts</name><affiliation wicri:level="1"><mods:affiliation>The Alfred Hospital and Monash University, Vic., Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>The Alfred Hospital and Monash University, Vic., Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Rosenberg, W M" sort="Rosenberg, W M" uniqKey="Rosenberg W" first="W. M." last="Rosenberg">W. M. Rosenberg</name><affiliation wicri:level="1"><mods:affiliation>Division of Medicine, UCL Institute for Liver and Digestive Health, University College London, London, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Medicine, UCL Institute for Liver and Digestive Health, University College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Roudot Horaval, F" sort="Roudot Horaval, F" uniqKey="Roudot Horaval F" first="F." last="Roudot-Thoraval">F. Roudot-Thoraval</name><affiliation wicri:level="1"><mods:affiliation>Département Santé Publique, Hôpital Henri Mondor, Créteil, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Département Santé Publique, Hôpital Henri Mondor, Créteil</wicri:regionArea></affiliation></author><author><name sortKey="Ryder, S D" sort="Ryder, S D" uniqKey="Ryder S" first="S. D." last="Ryder">S. D. Ryder</name><affiliation wicri:level="1"><mods:affiliation>Nottingham University Hospitals NHS Trust and Biomedical Research Unit, Nottingham, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Nottingham University Hospitals NHS Trust and Biomedical Research Unit, Nottingham</wicri:regionArea></affiliation></author><author><name sortKey="Sarmento Astro, R" sort="Sarmento Astro, R" uniqKey="Sarmento Astro R" first="R." last="Sarmento-Castro">R. Sarmento-Castro</name><affiliation wicri:level="1"><mods:affiliation>Infectious Diseases Department, Centro Hospitalar do Porto, Porto, Portugal</mods:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Infectious Diseases Department, Centro Hospitalar do Porto, Porto</wicri:regionArea></affiliation></author><author><name sortKey="Semela, D" sort="Semela, D" uniqKey="Semela D" first="D." last="Semela">D. Semela</name><affiliation wicri:level="1"><mods:affiliation>Division of Gastroenterology & Hepatology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland</mods:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Division of Gastroenterology & Hepatology, Cantonal Hospital St. Gallen, St. Gallen</wicri:regionArea></affiliation></author><author><name sortKey="Sherman, M" sort="Sherman, M" uniqKey="Sherman M" first="M." last="Sherman">M. Sherman</name><affiliation wicri:level="1"><mods:affiliation>Toronto General Hospital, University Health Network/University of Toronto, ON, Toronto, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Toronto General Hospital, University Health Network/University of Toronto, ON, Toronto</wicri:regionArea></affiliation></author><author><name sortKey="Shiha, G E" sort="Shiha, G E" uniqKey="Shiha G" first="G. E." last="Shiha">G. E. Shiha</name><affiliation wicri:level="1"><mods:affiliation>Egyptian Liver Research Institute And Hospital, Dakahliah, Egypt</mods:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Egyptian Liver Research Institute And Hospital, Dakahliah</wicri:regionArea></affiliation></author><author><name sortKey="Sievert, W" sort="Sievert, W" uniqKey="Sievert W" first="W." last="Sievert">W. Sievert</name><affiliation wicri:level="1"><mods:affiliation>Monash University and Monash Health, Vic., Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Monash University and Monash Health, Vic., Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Sperl, J" sort="Sperl, J" uniqKey="Sperl J" first="J." last="Sperl">J. Sperl</name><affiliation wicri:level="1"><mods:affiliation>Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic</mods:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague</wicri:regionArea></affiliation></author><author><name sortKey="St Rkel, P" sort="St Rkel, P" uniqKey="St Rkel P" first="P." last="St Rkel">P. St Rkel</name><affiliation wicri:level="1"><mods:affiliation>Cliniques Universitaires Saint‐Luc, Université Catholique de Louvain, Brussel, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Cliniques Universitaires Saint‐Luc, Université Catholique de Louvain, Brussel</wicri:regionArea></affiliation></author><author><name sortKey="Stauber, R E" sort="Stauber, R E" uniqKey="Stauber R" first="R. E." last="Stauber">R. E. Stauber</name><affiliation wicri:level="1"><mods:affiliation>Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Thompson, A J" sort="Thompson, A J" uniqKey="Thompson A" first="A. J." last="Thompson">A. J. Thompson</name><affiliation wicri:level="1"><mods:affiliation>Department of Gastroenterology, St Vincent's Hospital and the University of Melbourne, Vic., Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Gastroenterology, St Vincent's Hospital and the University of Melbourne, Vic., Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Urbanek, P" sort="Urbanek, P" uniqKey="Urbanek P" first="P." last="Urbanek">P. Urbanek</name><affiliation wicri:level="1"><mods:affiliation>Department of Internal Medicine, 1st Faculty of Medicine, Charles University in Prague and Central Military Hospital, Prague, Czech Republic</mods:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Internal Medicine, 1st Faculty of Medicine, Charles University in Prague and Central Military Hospital, Prague</wicri:regionArea></affiliation></author><author><name sortKey="Van Damme, P" sort="Van Damme, P" uniqKey="Van Damme P" first="P." last="Van Damme">P. Van Damme</name><affiliation wicri:level="1"><mods:affiliation>Universiteit Antwerpen, Antwerpen, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Universiteit Antwerpen, Antwerpen</wicri:regionArea></affiliation></author><author><name sortKey="Van Thiel, I" sort="Van Thiel, I" uniqKey="Van Thiel I" first="I." last="Van Thiel">I. Van Thiel</name><affiliation wicri:level="1"><mods:affiliation>European Liver Patients Association, Sint‐Truiden, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>European Liver Patients Association, Sint‐Truiden</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Deutsche Leberhilfe e.V., Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Deutsche Leberhilfe e.V., Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Van Vlierberghe, H" sort="Van Vlierberghe, H" uniqKey="Van Vlierberghe H" first="H." last="Van Vlierberghe">H. Van Vlierberghe</name><affiliation wicri:level="1"><mods:affiliation>Ghent University Hospital, Ghent, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Ghent University Hospital, Ghent</wicri:regionArea></affiliation></author><author><name sortKey="Vandijck, D" sort="Vandijck, D" uniqKey="Vandijck D" first="D." last="Vandijck">D. Vandijck</name><affiliation wicri:level="1"><mods:affiliation>Department of Health Economics & Patient Safety, Ghent University, Belgium Hasselt University, Diepenbeek, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Health Economics & Patient Safety, Ghent University, Belgium Hasselt University, Diepenbeek</wicri:regionArea></affiliation></author><author><name sortKey="Wedemeyer, H" sort="Wedemeyer, H" uniqKey="Wedemeyer H" first="H." last="Wedemeyer">H. Wedemeyer</name><affiliation wicri:level="1"><mods:affiliation>Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Weis, N" sort="Weis, N" uniqKey="Weis N" first="N." last="Weis">N. Weis</name><affiliation wicri:level="1"><mods:affiliation>Copenhagen University Hospital, Hvidovre, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen University Hospital, Hvidovre</wicri:regionArea></affiliation></author><author><name sortKey="Wiegand, J" sort="Wiegand, J" uniqKey="Wiegand J" first="J." last="Wiegand">J. Wiegand</name><affiliation wicri:level="1"><mods:affiliation>Infectious Diseases, Ankara University, Ankara, Turkey</mods:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Infectious Diseases, Ankara University, Ankara</wicri:regionArea></affiliation></author><author><name sortKey="Yosry, A" sort="Yosry, A" uniqKey="Yosry A" first="A." last="Yosry">A. Yosry</name><affiliation wicri:level="1"><mods:affiliation>Cairo University, Cairo, Egypt</mods:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Cairo University, Cairo</wicri:regionArea></affiliation></author><author><name sortKey="Zekry, A" sort="Zekry, A" uniqKey="Zekry A" first="A." last="Zekry">A. Zekry</name><affiliation wicri:level="1"><mods:affiliation>St George Hospital Clinical School of Medicine and School of Medical Science, University of New South Wales, NSW, Sydney, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>St George Hospital Clinical School of Medicine and School of Medical Science, University of New South Wales, NSW, Sydney</wicri:regionArea></affiliation></author><author><name sortKey="Cornberg, M" sort="Cornberg, M" uniqKey="Cornberg M" first="M." last="Cornberg">M. Cornberg</name><affiliation wicri:level="1"><mods:affiliation>Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Mullhaupt, B" sort="Mullhaupt, B" uniqKey="Mullhaupt B" first="B." last="Müllhaupt">B. Müllhaupt</name><affiliation wicri:level="1"><mods:affiliation>Swiss HPB (Hepato‐Pancreato‐Biliary) Center and Department of Gastroenterology and Hepatology, University Hospital Zürich, Zürich, Switzerland</mods:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss HPB (Hepato‐Pancreato‐Biliary) Center and Department of Gastroenterology and Hepatology, University Hospital Zürich, Zürich</wicri:regionArea></affiliation></author><author><name sortKey="Estes, C" sort="Estes, C" uniqKey="Estes C" first="C." last="Estes">C. Estes</name><affiliation wicri:level="1"><mods:affiliation>Center for Disease Analysis, Colorado, Louisville, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Disease Analysis, Colorado, Louisville</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:6F5499030B2D47269785C4D57593C4C552FA1B5F</idno><date when="2014" year="2014">2014</date><idno type="doi">10.1111/jvh.12248</idno><idno type="url">https://api.istex.fr/document/6F5499030B2D47269785C4D57593C4C552FA1B5F/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001486</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001486</idno><idno type="wicri:Area/Istex/Curation">001486</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm</title><author><name sortKey="Razavi, H" sort="Razavi, H" uniqKey="Razavi H" first="H." last="Razavi">H. Razavi</name><affiliation wicri:level="1"><mods:affiliation>Center for Disease Analysis, Colorado, Louisville, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Disease Analysis, Colorado, Louisville</wicri:regionArea></affiliation><affiliation><mods:affiliation>Correspondence: Homie A. Razavi, Center for Disease Analysis, 901 Front Street, Suite 291, Louisville, CO 80027, USA.E‐mail:</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: homie.razavi@centerforda.com</mods:affiliation></affiliation></author><author><name sortKey="Waked, I" sort="Waked, I" uniqKey="Waked I" first="I." last="Waked">I. Waked</name><affiliation wicri:level="1"><mods:affiliation>National Liver Institute, Menoufiya, Egypt</mods:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>National Liver Institute, Menoufiya</wicri:regionArea></affiliation></author><author><name sortKey="Sarrazin, C" sort="Sarrazin, C" uniqKey="Sarrazin C" first="C." last="Sarrazin">C. Sarrazin</name><affiliation wicri:level="1"><mods:affiliation>J.W. Goethe University Hospital, Frankfurt, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>J.W. Goethe University Hospital, Frankfurt</wicri:regionArea></affiliation></author><author><name sortKey="Myers, R P" sort="Myers, R P" uniqKey="Myers R" first="R. P." last="Myers">R. P. Myers</name><affiliation wicri:level="1"><mods:affiliation>Liver Unit, Division of Gastroenterology and Hepatology, University of Calgary, AB, Calgary, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Liver Unit, Division of Gastroenterology and Hepatology, University of Calgary, AB, Calgary</wicri:regionArea></affiliation></author><author><name sortKey="Idilman, R" sort="Idilman, R" uniqKey="Idilman R" first="R." last="Idilman">R. Idilman</name><affiliation wicri:level="1"><mods:affiliation>Department of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey</mods:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Gastroenterology, Ankara University School of Medicine, Ankara</wicri:regionArea></affiliation></author><author><name sortKey="Calinas, F" sort="Calinas, F" uniqKey="Calinas F" first="F." last="Calinas">F. Calinas</name><affiliation wicri:level="1"><mods:affiliation>Gastroenterology Department, Centro Hospitalar de Lisboa Central – Hospital Santo António Capuchos, Lisboa, Portugal</mods:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Gastroenterology Department, Centro Hospitalar de Lisboa Central – Hospital Santo António Capuchos, Lisboa</wicri:regionArea></affiliation></author><author><name sortKey="Vogel, W" sort="Vogel, W" uniqKey="Vogel W" first="W." last="Vogel">W. Vogel</name><affiliation wicri:level="1"><mods:affiliation>Innsbruck Medical University, Innsbruck, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Innsbruck Medical University, Innsbruck</wicri:regionArea></affiliation></author><author><name sortKey="Mendes Correa, M C" sort="Mendes Correa, M C" uniqKey="Mendes Correa M" first="M. C." last="Mendes Correa">M. C. Mendes Correa</name><affiliation wicri:level="1"><mods:affiliation>School of Medicine‐ Universidade de São Paulo, São Paulo, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>School of Medicine‐ Universidade de São Paulo, São Paulo</wicri:regionArea></affiliation></author><author><name sortKey="Hezode, C" sort="Hezode, C" uniqKey="Hezode C" first="C." last="Hézode">C. Hézode</name><affiliation wicri:level="1"><mods:affiliation>Service d' Hépato‐Gastroentérologie, Hôpital Henri Mondor, Créteil, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service d' Hépato‐Gastroentérologie, Hôpital Henri Mondor, Créteil</wicri:regionArea></affiliation></author><author><name sortKey="Lazaro, P" sort="Lazaro, P" uniqKey="Lazaro P" first="P." last="Lázaro">P. Lázaro</name><affiliation wicri:level="1"><mods:affiliation>Advanced Techniques in Health Services Research (TAISS), Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Advanced Techniques in Health Services Research (TAISS), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Akarca, U" sort="Akarca, U" uniqKey="Akarca U" first="U." last="Akarca">U. Akarca</name><affiliation wicri:level="1"><mods:affiliation>Gastroenterology, Ege University, Izmir, Turkey</mods:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Gastroenterology, Ege University, Izmir</wicri:regionArea></affiliation></author><author><name sortKey="Aleman, S" sort="Aleman, S" uniqKey="Aleman S" first="S." last="Aleman">S. Aleman</name><affiliation wicri:level="1"><mods:affiliation>Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medicine Huddinge, Karolinska Institutet, Stockholm</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Department of Gastroenterology and Hepatology/Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Gastroenterology and Hepatology/Infectious Diseases, Karolinska University Hospital, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Bal K, " sort="Bal K, " uniqKey="Bal K " first="" last="Bal K"> Bal K</name><affiliation wicri:level="1"><mods:affiliation>Infectious Diseases, Ankara University, Ankara, Turkey</mods:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Infectious Diseases, Ankara University, Ankara</wicri:regionArea></affiliation></author><author><name sortKey="Berg, T" sort="Berg, T" uniqKey="Berg T" first="T." last="Berg">T. Berg</name><affiliation wicri:level="1"><mods:affiliation>University of Leipzig, Leipzig, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Leipzig, Leipzig</wicri:regionArea></affiliation></author><author><name sortKey="Bihl, F" sort="Bihl, F" uniqKey="Bihl F" first="F." last="Bihl">F. Bihl</name><affiliation wicri:level="1"><mods:affiliation>Gastroenterology Department, Ospedale Cantonale, Bellinzona, Switzerland</mods:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Gastroenterology Department, Ospedale Cantonale, Bellinzona</wicri:regionArea></affiliation></author><author><name sortKey="Bilodeau, M" sort="Bilodeau, M" uniqKey="Bilodeau M" first="M." last="Bilodeau">M. Bilodeau</name><affiliation wicri:level="1"><mods:affiliation>Liver Unit, Department of Medicine, Université de Montréal, QC, Montréal, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Liver Unit, Department of Medicine, Université de Montréal, QC, Montréal</wicri:regionArea></affiliation></author><author><name sortKey="Blasco, A J" sort="Blasco, A J" uniqKey="Blasco A" first="A. J." last="Blasco">A. J. Blasco</name><affiliation wicri:level="1"><mods:affiliation>Advanced Techniques in Health Services Research (TAISS), Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Advanced Techniques in Health Services Research (TAISS), Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Brandao Mello, C E" sort="Brandao Mello, C E" uniqKey="Brandao Mello C" first="C. E." last="Brandão Mello">C. E. Brandão Mello</name><affiliation wicri:level="1"><mods:affiliation>Department of Gastroenterology, Federal University of the State of Rio de Janeiro, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Gastroenterology, Federal University of the State of Rio de Janeiro, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro</wicri:regionArea></affiliation></author><author><name sortKey="Bruggmann, P" sort="Bruggmann, P" uniqKey="Bruggmann P" first="P." last="Bruggmann">P. Bruggmann</name><affiliation wicri:level="1"><mods:affiliation>Arud Centres for Addiction Medicine, Zurich, Switzerland</mods:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Arud Centres for Addiction Medicine, Zurich</wicri:regionArea></affiliation></author><author><name sortKey="Buti, M" sort="Buti, M" uniqKey="Buti M" first="M." last="Buti">M. Buti</name><affiliation wicri:level="1"><mods:affiliation>Hospital Vall d'Hebron, CIBERehd, Barcelona, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital Vall d'Hebron, CIBERehd, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Calleja, J L" sort="Calleja, J L" uniqKey="Calleja J" first="J. L." last="Calleja">J. L. Calleja</name><affiliation wicri:level="1"><mods:affiliation>Hospital Puerta de Hierro, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital Puerta de Hierro, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Cheinquer, H" sort="Cheinquer, H" uniqKey="Cheinquer H" first="H." last="Cheinquer">H. Cheinquer</name><affiliation wicri:level="1"><mods:affiliation>Hospital das Clínicas da Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Hospital das Clínicas da Universidade Federal do Rio Grande do Sul, Porto Alegre</wicri:regionArea></affiliation></author><author><name sortKey="Christensen, P B" sort="Christensen, P B" uniqKey="Christensen P" first="P. B." last="Christensen">P. B. Christensen</name><affiliation wicri:level="1"><mods:affiliation>Department of Infectious Diseases, Odense University Hospital, Odense, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Infectious Diseases, Odense University Hospital, Odense</wicri:regionArea></affiliation></author><author><name sortKey="Clausen, M" sort="Clausen, M" uniqKey="Clausen M" first="M." last="Clausen">M. Clausen</name><affiliation wicri:level="1"><mods:affiliation>Region Hospital Hovedstaden, Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Region Hospital Hovedstaden, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Coelho, H S M" sort="Coelho, H S M" uniqKey="Coelho H" first="H. S. M." last="Coelho">H. S. M. Coelho</name><affiliation wicri:level="1"><mods:affiliation>Department of Clinical Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Clinical Medicine, Federal University of Rio de Janeiro, Rio de Janeiro</wicri:regionArea></affiliation></author><author><name sortKey="Cramp, M E" sort="Cramp, M E" uniqKey="Cramp M" first="M. E." last="Cramp">M. E. Cramp</name><affiliation wicri:level="1"><mods:affiliation>Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth</wicri:regionArea></affiliation></author><author><name sortKey="Dore, G J" sort="Dore, G J" uniqKey="Dore G" first="G. J." last="Dore">G. J. Dore</name><affiliation wicri:level="1"><mods:affiliation>Kirby Institute, University of New South Wales, NSW, Sydney, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Kirby Institute, University of New South Wales, NSW, Sydney</wicri:regionArea></affiliation></author><author><name sortKey="Doss, W" sort="Doss, W" uniqKey="Doss W" first="W." last="Doss">W. Doss</name><affiliation wicri:level="1"><mods:affiliation>Cairo University, Cairo, Egypt</mods:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Cairo University, Cairo</wicri:regionArea></affiliation></author><author><name sortKey="Duberg, A S" sort="Duberg, A S" uniqKey="Duberg A" first="A. S." last="Duberg">A. S. Duberg</name><affiliation wicri:level="1"><mods:affiliation>Department of Infectious Diseases, Örebro University Hospital, Örebro, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Infectious Diseases, Örebro University Hospital, Örebro</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>School of Health and Medical Sciences, Örebro University, Örebro, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>School of Health and Medical Sciences, Örebro University, Örebro</wicri:regionArea></affiliation></author><author><name sortKey="El Ayed, M H" sort="El Ayed, M H" uniqKey="El Ayed M" first="M. H." last="El-Sayed">M. H. El-Sayed</name><affiliation wicri:level="1"><mods:affiliation>Ain Shams University, Cairo, Egypt</mods:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Ain Shams University, Cairo</wicri:regionArea></affiliation></author><author><name sortKey="Ergor, G" sort="Ergor, G" uniqKey="Ergor G" first="G." last="Ergör">G. Ergör</name><affiliation wicri:level="1"><mods:affiliation>Public Health and Epidemiology, Dokuz Eylul University, Izmir, Turkey</mods:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Public Health and Epidemiology, Dokuz Eylul University, Izmir</wicri:regionArea></affiliation></author><author><name sortKey="Esmat, G" sort="Esmat, G" uniqKey="Esmat G" first="G." last="Esmat">G. Esmat</name><affiliation wicri:level="1"><mods:affiliation>Cairo University, Cairo, Egypt</mods:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Cairo University, Cairo</wicri:regionArea></affiliation></author><author><name sortKey="Falconer, K" sort="Falconer, K" uniqKey="Falconer K" first="K." last="Falconer">K. Falconer</name><affiliation wicri:level="1"><mods:affiliation>Unit of Infectious Diseases, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Unit of Infectious Diseases, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Felix, J" sort="Felix, J" uniqKey="Felix J" first="J." last="Félix">J. Félix</name><affiliation wicri:level="1"><mods:affiliation>Exigo Consultores, Alhos Vedros, Portugal</mods:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Exigo Consultores, Alhos Vedros</wicri:regionArea></affiliation></author><author><name sortKey="Ferraz, M L G" sort="Ferraz, M L G" uniqKey="Ferraz M" first="M. L. G." last="Ferraz">M. L. G. Ferraz</name><affiliation wicri:level="1"><mods:affiliation>Division of Gastroenterology, Federal University of São Paulo, São Paulo, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Division of Gastroenterology, Federal University of São Paulo, São Paulo</wicri:regionArea></affiliation></author><author><name sortKey="Ferreira, P R" sort="Ferreira, P R" uniqKey="Ferreira P" first="P. R." last="Ferreira">P. R. Ferreira</name><affiliation wicri:level="1"><mods:affiliation>Division of Infectious Disease, Federal University of São Paulo, São Paulo, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Division of Infectious Disease, Federal University of São Paulo, São Paulo</wicri:regionArea></affiliation></author><author><name sortKey="Frankova, S" sort="Frankova, S" uniqKey="Frankova S" first="S." last="Frankova">S. Frankova</name><affiliation wicri:level="1"><mods:affiliation>Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic</mods:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague</wicri:regionArea></affiliation></author><author><name sortKey="Garcia Amaniego, J" sort="Garcia Amaniego, J" uniqKey="Garcia Amaniego J" first="J." last="García-Samaniego">J. García-Samaniego</name><affiliation wicri:level="1"><mods:affiliation>Hospital Carlos III, CIBERehd, Madrid, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital Carlos III, CIBERehd, Madrid</wicri:regionArea></affiliation></author><author><name sortKey="Gerstoft, J" sort="Gerstoft, J" uniqKey="Gerstoft J" first="J." last="Gerstoft">J. Gerstoft</name><affiliation wicri:level="1"><mods:affiliation>University of Copenhagen, Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>University of Copenhagen, Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="Giria, J A" sort="Giria, J A" uniqKey="Giria J" first="J. A." last="Giria">J. A. Giria</name><affiliation wicri:level="1"><mods:affiliation>Direcção‐Geral da Saúde, Lisboa, Portugal</mods:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Direcção‐Geral da Saúde, Lisboa</wicri:regionArea></affiliation></author><author><name sortKey="Goncales Jr, F L" sort="Goncales Jr, F L" uniqKey="Goncales Jr F" first="F. L." last="Gonçales Jr">F. L. Gonçales Jr</name><affiliation wicri:level="1"><mods:affiliation>Grupo de Estudo das Hepatites, Disciplina de Doenças Infecciosas, Departamento de Clínica Médica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, UNICAMP, São Paulo, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Grupo de Estudo das Hepatites, Disciplina de Doenças Infecciosas, Departamento de Clínica Médica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, UNICAMP, São Paulo</wicri:regionArea></affiliation></author><author><name sortKey="Gower, E" sort="Gower, E" uniqKey="Gower E" first="E." last="Gower">E. Gower</name><affiliation wicri:level="1"><mods:affiliation>Center for Disease Analysis, Colorado, Louisville, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Disease Analysis, Colorado, Louisville</wicri:regionArea></affiliation></author><author><name sortKey="Gschwantler, M" sort="Gschwantler, M" uniqKey="Gschwantler M" first="M." last="Gschwantler">M. Gschwantler</name><affiliation wicri:level="1"><mods:affiliation>Department of Internal Medicine IV, Wilhelminenspital, Vienna, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Internal Medicine IV, Wilhelminenspital, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Guimaraes Pessoa, M" sort="Guimaraes Pessoa, M" uniqKey="Guimaraes Pessoa M" first="M." last="Guimarães Pessôa">M. Guimarães Pessôa</name><affiliation wicri:level="1"><mods:affiliation>Division of Gastroenterology and Hepatology, University of São Paulo School of Medicine, São Paulo, Brazil</mods:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Division of Gastroenterology and Hepatology, University of São Paulo School of Medicine, São Paulo</wicri:regionArea></affiliation></author><author><name sortKey="Hindman, S J" sort="Hindman, S J" uniqKey="Hindman S" first="S. J." last="Hindman">S. J. Hindman</name><affiliation wicri:level="1"><mods:affiliation>Center for Disease Analysis, Colorado, Louisville, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Disease Analysis, Colorado, Louisville</wicri:regionArea></affiliation></author><author><name sortKey="Hofer, H" sort="Hofer, H" uniqKey="Hofer H" first="H." last="Hofer">H. Hofer</name><affiliation wicri:level="1"><mods:affiliation>Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna</wicri:regionArea></affiliation></author><author><name sortKey="Husa, P" sort="Husa, P" uniqKey="Husa P" first="P." last="Husa">P. Husa</name><affiliation wicri:level="1"><mods:affiliation>Clinic of Infectious Diseases of the University Hospital Brno, Masaryk University Brno, Brno, Czech Republic</mods:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Clinic of Infectious Diseases of the University Hospital Brno, Masaryk University Brno, Brno</wicri:regionArea></affiliation></author><author><name sortKey="K Berg, M" sort="K Berg, M" uniqKey="K Berg M" first="M." last="K Berg">M. K Berg</name><affiliation wicri:level="1"><mods:affiliation>Unit of Infectious Diseases, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Unit of Infectious Diseases, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm</wicri:regionArea></affiliation></author><author><name sortKey="Kaita, K D E" sort="Kaita, K D E" uniqKey="Kaita K" first="K. D. E." last="Kaita">K. D. E. Kaita</name><affiliation wicri:level="1"><mods:affiliation>Section of Hepatology, Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Section of Hepatology, Department of Internal Medicine, University of Manitoba, Winnipeg, MB</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Viral Hepatitis Investigative Unit, Health Sciences Centre, MB, Winnipeg, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Viral Hepatitis Investigative Unit, Health Sciences Centre, MB, Winnipeg</wicri:regionArea></affiliation></author><author><name sortKey="Kautz, A" sort="Kautz, A" uniqKey="Kautz A" first="A." last="Kautz">A. Kautz</name><affiliation wicri:level="1"><mods:affiliation>European Liver Patients Association, Sint‐Truiden, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>European Liver Patients Association, Sint‐Truiden</wicri:regionArea></affiliation></author><author><name sortKey="Kaymakoglu, S" sort="Kaymakoglu, S" uniqKey="Kaymakoglu S" first="S." last="Kaymakoglu">S. Kaymakoglu</name><affiliation wicri:level="1"><mods:affiliation>Gastroenterology, Istanbul University, Istanbul, Turkey</mods:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Gastroenterology, Istanbul University, Istanbul</wicri:regionArea></affiliation></author><author><name sortKey="Krajden, M" sort="Krajden, M" uniqKey="Krajden M" first="M." last="Krajden">M. Krajden</name><affiliation wicri:level="1"><mods:affiliation>British Columbia Centre for Disease Control, University of British Columbia, BC, Vancouver, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>British Columbia Centre for Disease Control, University of British Columbia, BC, Vancouver</wicri:regionArea></affiliation></author><author><name sortKey="Krarup, H" sort="Krarup, H" uniqKey="Krarup H" first="H." last="Krarup">H. Krarup</name><affiliation wicri:level="1"><mods:affiliation>Department of Medical Gastroenterology and Section of Molecular Diagnostics, Cinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Medical Gastroenterology and Section of Molecular Diagnostics, Cinical Biochemistry, Aalborg University Hospital, Aalborg</wicri:regionArea></affiliation></author><author><name sortKey="Laleman, W" sort="Laleman, W" uniqKey="Laleman W" first="W." last="Laleman">W. Laleman</name><affiliation wicri:level="1"><mods:affiliation>University Hospitals Leuven, KU Leuven, Leuven, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>University Hospitals Leuven, KU Leuven, Leuven</wicri:regionArea></affiliation></author><author><name sortKey="Lavanchy, D" sort="Lavanchy, D" uniqKey="Lavanchy D" first="D." last="Lavanchy">D. Lavanchy</name><affiliation wicri:level="1"><mods:affiliation>Independent Consultant, Denges, Switzerland</mods:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Independent Consultant, Denges</wicri:regionArea></affiliation></author><author><name sortKey="Marinho, R T" sort="Marinho, R T" uniqKey="Marinho R" first="R. T." last="Marinho">R. T. Marinho</name><affiliation wicri:level="1"><mods:affiliation>Gastroenterology Department, Centro Hospitalar de Lisboa Norte, Hospital Santa Maria, Lisboa, Portugal</mods:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Gastroenterology Department, Centro Hospitalar de Lisboa Norte, Hospital Santa Maria, Lisboa</wicri:regionArea></affiliation></author><author><name sortKey="Marotta, P" sort="Marotta, P" uniqKey="Marotta P" first="P." last="Marotta">P. Marotta</name><affiliation wicri:level="1"><mods:affiliation>Division of Gastroenterology, University of Western Ontario, ON, London, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Gastroenterology, University of Western Ontario, ON, London</wicri:regionArea></affiliation></author><author><name sortKey="Mauss, S" sort="Mauss, S" uniqKey="Mauss S" first="S." last="Mauss">S. Mauss</name><affiliation wicri:level="1"><mods:affiliation>Heinrich‐Heine University in Duesseldorf, Dusseldorf, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Heinrich‐Heine University in Duesseldorf, Dusseldorf</wicri:regionArea></affiliation></author><author><name sortKey="Moreno, C" sort="Moreno, C" uniqKey="Moreno C" first="C." last="Moreno">C. Moreno</name><affiliation wicri:level="1"><mods:affiliation>Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Erasme University Hospital, Université Libre de Bruxelles, Brussels</wicri:regionArea></affiliation></author><author><name sortKey="Murphy, K" sort="Murphy, K" uniqKey="Murphy K" first="K." last="Murphy">K. Murphy</name><affiliation wicri:level="1"><mods:affiliation>Center for Disease Analysis, Colorado, Louisville, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Disease Analysis, Colorado, Louisville</wicri:regionArea></affiliation></author><author><name sortKey="Negro, F" sort="Negro, F" uniqKey="Negro F" first="F." last="Negro">F. Negro</name><affiliation wicri:level="1"><mods:affiliation>Divisions of Gastroenterology and Hepatology and of Clinical Pathology, University Hospital, Genève, Switzerland</mods:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Divisions of Gastroenterology and Hepatology and of Clinical Pathology, University Hospital, Genève</wicri:regionArea></affiliation></author><author><name sortKey="Nemecek, V" sort="Nemecek, V" uniqKey="Nemecek V" first="V." last="Nemecek">V. Nemecek</name><affiliation wicri:level="1"><mods:affiliation>National Reference Laboratory for Hepatitis, National Institute of Public Health, Prague, Czech Republic</mods:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>National Reference Laboratory for Hepatitis, National Institute of Public Health, Prague</wicri:regionArea></affiliation></author><author><name sortKey="Ormeci, N" sort="Ormeci, N" uniqKey="Ormeci N" first="N." last="Örmeci">N. Örmeci</name><affiliation wicri:level="1"><mods:affiliation>Gastroenterology, Ankara University, Ankara, Turkey</mods:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Gastroenterology, Ankara University, Ankara</wicri:regionArea></affiliation></author><author><name sortKey=" Vrehus, A L H" sort=" Vrehus, A L H" uniqKey=" Vrehus A" first="A. L. H." last=" Vrehus">A. L. H. Vrehus</name><affiliation wicri:level="1"><mods:affiliation>Department of Infectious Diseases, Odense University Hospital, Odense, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Infectious Diseases, Odense University Hospital, Odense</wicri:regionArea></affiliation></author><author><name sortKey="Parkes, J" sort="Parkes, J" uniqKey="Parkes J" first="J." last="Parkes">J. Parkes</name><affiliation wicri:level="1"><mods:affiliation>University of Southhampton, Southhampton, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Southhampton, Southhampton</wicri:regionArea></affiliation></author><author><name sortKey="Pasini, K" sort="Pasini, K" uniqKey="Pasini K" first="K." last="Pasini">K. Pasini</name><affiliation wicri:level="1"><mods:affiliation>Center for Disease Analysis, Colorado, Louisville, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Disease Analysis, Colorado, Louisville</wicri:regionArea></affiliation></author><author><name sortKey="Peltekian, K M" sort="Peltekian, K M" uniqKey="Peltekian K" first="K. M." last="Peltekian">K. M. Peltekian</name><affiliation wicri:level="1"><mods:affiliation>Departments of Medicine and Surgery, Queen Elizabeth II Health Sciences Centre, Capital District Health Authority, Dalhousie University and Hepatology Services, NS, Halifax, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Departments of Medicine and Surgery, Queen Elizabeth II Health Sciences Centre, Capital District Health Authority, Dalhousie University and Hepatology Services, NS, Halifax</wicri:regionArea></affiliation></author><author><name sortKey="Ramji, A" sort="Ramji, A" uniqKey="Ramji A" first="A." last="Ramji">A. Ramji</name><affiliation wicri:level="1"><mods:affiliation>Department of Gastroenterology, University of British Columbia, BC, Vancouver, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Gastroenterology, University of British Columbia, BC, Vancouver</wicri:regionArea></affiliation></author><author><name sortKey="Reis, N" sort="Reis, N" uniqKey="Reis N" first="N." last="Reis">N. Reis</name><affiliation wicri:level="1"><mods:affiliation>Assembleia da República, Lisboa, Portugal</mods:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Assembleia da República, Lisboa</wicri:regionArea></affiliation></author><author><name sortKey="Roberts, S K" sort="Roberts, S K" uniqKey="Roberts S" first="S. K." last="Roberts">S. K. Roberts</name><affiliation wicri:level="1"><mods:affiliation>The Alfred Hospital and Monash University, Vic., Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>The Alfred Hospital and Monash University, Vic., Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Rosenberg, W M" sort="Rosenberg, W M" uniqKey="Rosenberg W" first="W. M." last="Rosenberg">W. M. Rosenberg</name><affiliation wicri:level="1"><mods:affiliation>Division of Medicine, UCL Institute for Liver and Digestive Health, University College London, London, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Medicine, UCL Institute for Liver and Digestive Health, University College London, London</wicri:regionArea></affiliation></author><author><name sortKey="Roudot Horaval, F" sort="Roudot Horaval, F" uniqKey="Roudot Horaval F" first="F." last="Roudot-Thoraval">F. Roudot-Thoraval</name><affiliation wicri:level="1"><mods:affiliation>Département Santé Publique, Hôpital Henri Mondor, Créteil, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Département Santé Publique, Hôpital Henri Mondor, Créteil</wicri:regionArea></affiliation></author><author><name sortKey="Ryder, S D" sort="Ryder, S D" uniqKey="Ryder S" first="S. D." last="Ryder">S. D. Ryder</name><affiliation wicri:level="1"><mods:affiliation>Nottingham University Hospitals NHS Trust and Biomedical Research Unit, Nottingham, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Nottingham University Hospitals NHS Trust and Biomedical Research Unit, Nottingham</wicri:regionArea></affiliation></author><author><name sortKey="Sarmento Astro, R" sort="Sarmento Astro, R" uniqKey="Sarmento Astro R" first="R." last="Sarmento-Castro">R. Sarmento-Castro</name><affiliation wicri:level="1"><mods:affiliation>Infectious Diseases Department, Centro Hospitalar do Porto, Porto, Portugal</mods:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Infectious Diseases Department, Centro Hospitalar do Porto, Porto</wicri:regionArea></affiliation></author><author><name sortKey="Semela, D" sort="Semela, D" uniqKey="Semela D" first="D." last="Semela">D. Semela</name><affiliation wicri:level="1"><mods:affiliation>Division of Gastroenterology & Hepatology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland</mods:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Division of Gastroenterology & Hepatology, Cantonal Hospital St. Gallen, St. Gallen</wicri:regionArea></affiliation></author><author><name sortKey="Sherman, M" sort="Sherman, M" uniqKey="Sherman M" first="M." last="Sherman">M. Sherman</name><affiliation wicri:level="1"><mods:affiliation>Toronto General Hospital, University Health Network/University of Toronto, ON, Toronto, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Toronto General Hospital, University Health Network/University of Toronto, ON, Toronto</wicri:regionArea></affiliation></author><author><name sortKey="Shiha, G E" sort="Shiha, G E" uniqKey="Shiha G" first="G. E." last="Shiha">G. E. Shiha</name><affiliation wicri:level="1"><mods:affiliation>Egyptian Liver Research Institute And Hospital, Dakahliah, Egypt</mods:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Egyptian Liver Research Institute And Hospital, Dakahliah</wicri:regionArea></affiliation></author><author><name sortKey="Sievert, W" sort="Sievert, W" uniqKey="Sievert W" first="W." last="Sievert">W. Sievert</name><affiliation wicri:level="1"><mods:affiliation>Monash University and Monash Health, Vic., Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Monash University and Monash Health, Vic., Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Sperl, J" sort="Sperl, J" uniqKey="Sperl J" first="J." last="Sperl">J. Sperl</name><affiliation wicri:level="1"><mods:affiliation>Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic</mods:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague</wicri:regionArea></affiliation></author><author><name sortKey="St Rkel, P" sort="St Rkel, P" uniqKey="St Rkel P" first="P." last="St Rkel">P. St Rkel</name><affiliation wicri:level="1"><mods:affiliation>Cliniques Universitaires Saint‐Luc, Université Catholique de Louvain, Brussel, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Cliniques Universitaires Saint‐Luc, Université Catholique de Louvain, Brussel</wicri:regionArea></affiliation></author><author><name sortKey="Stauber, R E" sort="Stauber, R E" uniqKey="Stauber R" first="R. E." last="Stauber">R. E. Stauber</name><affiliation wicri:level="1"><mods:affiliation>Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz</wicri:regionArea></affiliation></author><author><name sortKey="Thompson, A J" sort="Thompson, A J" uniqKey="Thompson A" first="A. J." last="Thompson">A. J. Thompson</name><affiliation wicri:level="1"><mods:affiliation>Department of Gastroenterology, St Vincent's Hospital and the University of Melbourne, Vic., Melbourne, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Gastroenterology, St Vincent's Hospital and the University of Melbourne, Vic., Melbourne</wicri:regionArea></affiliation></author><author><name sortKey="Urbanek, P" sort="Urbanek, P" uniqKey="Urbanek P" first="P." last="Urbanek">P. Urbanek</name><affiliation wicri:level="1"><mods:affiliation>Department of Internal Medicine, 1st Faculty of Medicine, Charles University in Prague and Central Military Hospital, Prague, Czech Republic</mods:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Department of Internal Medicine, 1st Faculty of Medicine, Charles University in Prague and Central Military Hospital, Prague</wicri:regionArea></affiliation></author><author><name sortKey="Van Damme, P" sort="Van Damme, P" uniqKey="Van Damme P" first="P." last="Van Damme">P. Van Damme</name><affiliation wicri:level="1"><mods:affiliation>Universiteit Antwerpen, Antwerpen, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Universiteit Antwerpen, Antwerpen</wicri:regionArea></affiliation></author><author><name sortKey="Van Thiel, I" sort="Van Thiel, I" uniqKey="Van Thiel I" first="I." last="Van Thiel">I. Van Thiel</name><affiliation wicri:level="1"><mods:affiliation>European Liver Patients Association, Sint‐Truiden, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>European Liver Patients Association, Sint‐Truiden</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Deutsche Leberhilfe e.V., Cologne, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Deutsche Leberhilfe e.V., Cologne</wicri:regionArea></affiliation></author><author><name sortKey="Van Vlierberghe, H" sort="Van Vlierberghe, H" uniqKey="Van Vlierberghe H" first="H." last="Van Vlierberghe">H. Van Vlierberghe</name><affiliation wicri:level="1"><mods:affiliation>Ghent University Hospital, Ghent, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Ghent University Hospital, Ghent</wicri:regionArea></affiliation></author><author><name sortKey="Vandijck, D" sort="Vandijck, D" uniqKey="Vandijck D" first="D." last="Vandijck">D. Vandijck</name><affiliation wicri:level="1"><mods:affiliation>Department of Health Economics & Patient Safety, Ghent University, Belgium Hasselt University, Diepenbeek, Belgium</mods:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Health Economics & Patient Safety, Ghent University, Belgium Hasselt University, Diepenbeek</wicri:regionArea></affiliation></author><author><name sortKey="Wedemeyer, H" sort="Wedemeyer, H" uniqKey="Wedemeyer H" first="H." last="Wedemeyer">H. Wedemeyer</name><affiliation wicri:level="1"><mods:affiliation>Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Weis, N" sort="Weis, N" uniqKey="Weis N" first="N." last="Weis">N. Weis</name><affiliation wicri:level="1"><mods:affiliation>Copenhagen University Hospital, Hvidovre, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen University Hospital, Hvidovre</wicri:regionArea></affiliation></author><author><name sortKey="Wiegand, J" sort="Wiegand, J" uniqKey="Wiegand J" first="J." last="Wiegand">J. Wiegand</name><affiliation wicri:level="1"><mods:affiliation>Infectious Diseases, Ankara University, Ankara, Turkey</mods:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Infectious Diseases, Ankara University, Ankara</wicri:regionArea></affiliation></author><author><name sortKey="Yosry, A" sort="Yosry, A" uniqKey="Yosry A" first="A." last="Yosry">A. Yosry</name><affiliation wicri:level="1"><mods:affiliation>Cairo University, Cairo, Egypt</mods:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Cairo University, Cairo</wicri:regionArea></affiliation></author><author><name sortKey="Zekry, A" sort="Zekry, A" uniqKey="Zekry A" first="A." last="Zekry">A. Zekry</name><affiliation wicri:level="1"><mods:affiliation>St George Hospital Clinical School of Medicine and School of Medical Science, University of New South Wales, NSW, Sydney, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>St George Hospital Clinical School of Medicine and School of Medical Science, University of New South Wales, NSW, Sydney</wicri:regionArea></affiliation></author><author><name sortKey="Cornberg, M" sort="Cornberg, M" uniqKey="Cornberg M" first="M." last="Cornberg">M. Cornberg</name><affiliation wicri:level="1"><mods:affiliation>Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover</wicri:regionArea></affiliation></author><author><name sortKey="Mullhaupt, B" sort="Mullhaupt, B" uniqKey="Mullhaupt B" first="B." last="Müllhaupt">B. Müllhaupt</name><affiliation wicri:level="1"><mods:affiliation>Swiss HPB (Hepato‐Pancreato‐Biliary) Center and Department of Gastroenterology and Hepatology, University Hospital Zürich, Zürich, Switzerland</mods:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss HPB (Hepato‐Pancreato‐Biliary) Center and Department of Gastroenterology and Hepatology, University Hospital Zürich, Zürich</wicri:regionArea></affiliation></author><author><name sortKey="Estes, C" sort="Estes, C" uniqKey="Estes C" first="C." last="Estes">C. Estes</name><affiliation wicri:level="1"><mods:affiliation>Center for Disease Analysis, Colorado, Louisville, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Disease Analysis, Colorado, Louisville</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Viral Hepatitis</title><title level="j" type="sub">Hepatitis C Disease Burden & Strategies to Manage the Burden</title><title level="j" type="alt">JOURNAL OF VIRAL HEPATITIS</title><idno type="ISSN">1352-0504</idno><idno type="eISSN">1365-2893</idno><imprint><biblScope unit="vol">21</biblScope><biblScope unit="page" from="34">34</biblScope><biblScope unit="page" to="59">59</biblScope><biblScope unit="page-count">26</biblScope><date type="published" when="2014-05">2014-05</date></imprint><idno type="ISSN">1352-0504</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1352-0504</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">The disease burden of hepatitis C virus (HCV) is expected to increase as the infected population ages. A modelling approach was used to estimate the total number of viremic infections, diagnosed, treated and new infections in 2013. In addition, the model was used to estimate the change in the total number of HCV infections, the disease progression and mortality in 2013–2030. Finally, expert panel consensus was used to capture current treatment practices in each country. Using today's treatment paradigm, the total number of HCV infections is projected to decline or remain flat in all countries studied. However, in the same time period, the number of individuals with late‐stage liver disease is projected to increase. This study concluded that the current treatment rate and efficacy are not sufficient to manage the disease burden of HCV. Thus, alternative strategies are required to keep the number of HCV individuals with advanced liver disease and liver‐related deaths from increasing.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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