A review of methods used to study cognitive deficits in Parkinson's disease.
Identifieur interne : 001356 ( Ncbi/Curation ); précédent : 001355; suivant : 001357A review of methods used to study cognitive deficits in Parkinson's disease.
Auteurs : Abdul Qayyum Rana [Canada] ; Mohamed Sufian Masroor ; Atif Saeed KhanSource :
- Neurological research [ 1743-1328 ] ; 2013.
English descriptors
- KwdEn :
- MESH :
- complications : Parkinson Disease.
- diagnosis : Cognition Disorders, Learning Disorders.
- etiology : Cognition Disorders, Learning Disorders.
- Animals, Computer Simulation, Disease Models, Animal, Humans, Learning, Neuroimaging, Neuropsychological Tests.
Abstract
In addition to the classic motor symptoms of Parkinson's disease (PD), some patients suffer from a variety of non-motor symptoms. Cognitive deficits such as impairments to learning and memory have been noted in PD and pose a clinical concern. However, during early stages of the disease these deficits may be subtle and difficult to diagnose. To date, various methodologies have been used to identify and diagnose these impairments in PD; imaging studies, animal models, and computer simulated learning paradigms being the most popular. This review discusses the advantages and disadvantages of each method in studying cognitive deficits associated with PD.
DOI: 10.1179/1743132812Y.0000000118
PubMed: 23317792
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pubmed:23317792Le document en format XML
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<author><name sortKey="Masroor, Mohamed Sufian" sort="Masroor, Mohamed Sufian" uniqKey="Masroor M" first="Mohamed Sufian" last="Masroor">Mohamed Sufian Masroor</name>
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<author><name sortKey="Khan, Atif Saeed" sort="Khan, Atif Saeed" uniqKey="Khan A" first="Atif Saeed" last="Khan">Atif Saeed Khan</name>
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<series><title level="j">Neurological research</title>
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<term>Humans</term>
<term>Learning</term>
<term>Learning Disorders (diagnosis)</term>
<term>Learning Disorders (etiology)</term>
<term>Neuroimaging</term>
<term>Neuropsychological Tests</term>
<term>Parkinson Disease (complications)</term>
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<front><div type="abstract" xml:lang="en">In addition to the classic motor symptoms of Parkinson's disease (PD), some patients suffer from a variety of non-motor symptoms. Cognitive deficits such as impairments to learning and memory have been noted in PD and pose a clinical concern. However, during early stages of the disease these deficits may be subtle and difficult to diagnose. To date, various methodologies have been used to identify and diagnose these impairments in PD; imaging studies, animal models, and computer simulated learning paradigms being the most popular. This review discusses the advantages and disadvantages of each method in studying cognitive deficits associated with PD.</div>
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