ParkinsonCanadaV1, Main, Merge, bibRecord, 004052

Long-term progression in chronic manganism : Ten years of follow-up

Identifieur interne : 004052 ( Main/Merge ); précédent : 004051; suivant : 004053

Long-term progression in chronic manganism : Ten years of follow-up

Auteurs : C.-C. Huang [Taïwan] ; N.-S. Chu [Taïwan] ; C.-S. Lu [Taïwan] ; R.-S. Chen [Taïwan] ; D. B. Calne [Canada]

Source :

Neurology [ 0028-3878 ] ; 1998.

RBID : Pascal:98-0196229

Descripteurs français

Pascal (Inist)
- Intoxication, Manganèse, Chronique, Parkinsonisme, Imagerie RMN, Complication, Etude cas, Evolution, Long terme, Adulte, Manganisme.
Wicri :
- topic : Manganèse, Adulte.

English descriptors

KwdEn :
- Adult, Case study, Chronic, Complication, Evolution, Long term, Manganese, Nuclear magnetic resonance imaging, Parkinsonism, Poisoning.

Abstract

We studied the long-term clinical course of five patients with chronic manganese intoxication. The mean scores of the King's College Hospital Rating Scale for Parkinson's disease increased from 15.0 ± 4.2 in 1987 to 28.3 ± 6.70 in 1991 and then to 38.1 ± 12.9 in 1995. The deterioration was most prominent in gait, rigidity, speed of foot tapping, and writing. Tissue concentrations of manganese in blood, urine, scalp hair, and pubic hair returned to normal. Follow-up MRIs did not show paramagnetic high-signal intensity on T1-weighted images. The data indicate that clinical progression in patients with manganese parkinsonism continues even 10 years after cessation of exposure.

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to stream PascalFrancis, to step Corpus: 000E32
to stream PascalFrancis, to step Curation: 001091
to stream PascalFrancis, to step Checkpoint: 000D02

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Pascal:98-0196229

Le document en format XML

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<author><name sortKey="Huang, C C" sort="Huang, C C" uniqKey="Huang C" first="C.-C." last="Huang">C.-C. Huang</name>
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<term>Nuclear magnetic resonance imaging</term>
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<term>Manganèse</term>
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<front><div type="abstract" xml:lang="en">We studied the long-term clinical course of five patients with chronic manganese intoxication. The mean scores of the King's College Hospital Rating Scale for Parkinson's disease increased from 15.0 ± 4.2 in 1987 to 28.3 ± 6.70 in 1991 and then to 38.1 ± 12.9 in 1995. The deterioration was most prominent in gait, rigidity, speed of foot tapping, and writing. Tissue concentrations of manganese in blood, urine, scalp hair, and pubic hair returned to normal. Follow-up MRIs did not show paramagnetic high-signal intensity on T1-weighted images. The data indicate that clinical progression in patients with manganese parkinsonism continues even 10 years after cessation of exposure.</div>
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La maladie de Parkinson au Canada (serveur d'exploration)

Long-term progression in chronic manganism : Ten years of follow-up

Long-term progression in chronic manganism : Ten years of follow-up

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri