ParkinsonCanadaV1, PascalFrancis, Checkpoint, bibRecord, 000D02

Long-term progression in chronic manganism : Ten years of follow-up

Identifieur interne : 000D02 ( PascalFrancis/Checkpoint ); précédent : 000D01; suivant : 000D03

Long-term progression in chronic manganism : Ten years of follow-up

Auteurs : C.-C. Huang [Taïwan] ; N.-S. Chu [Taïwan] ; C.-S. Lu [Taïwan] ; R.-S. Chen [Taïwan] ; D. B. Calne [Canada]

Source :

Neurology [ 0028-3878 ] ; 1998.

RBID : Pascal:98-0196229

Descripteurs français

Pascal (Inist)
- Intoxication, Manganèse, Chronique, Parkinsonisme, Imagerie RMN, Complication, Etude cas, Evolution, Long terme, Adulte, Manganisme.
Wicri :
- topic : Manganèse, Adulte.

English descriptors

KwdEn :
- Adult, Case study, Chronic, Complication, Evolution, Long term, Manganese, Nuclear magnetic resonance imaging, Parkinsonism, Poisoning.

Abstract

We studied the long-term clinical course of five patients with chronic manganese intoxication. The mean scores of the King's College Hospital Rating Scale for Parkinson's disease increased from 15.0 ± 4.2 in 1987 to 28.3 ± 6.70 in 1991 and then to 38.1 ± 12.9 in 1995. The deterioration was most prominent in gait, rigidity, speed of foot tapping, and writing. Tissue concentrations of manganese in blood, urine, scalp hair, and pubic hair returned to normal. Follow-up MRIs did not show paramagnetic high-signal intensity on T1-weighted images. The data indicate that clinical progression in patients with manganese parkinsonism continues even 10 years after cessation of exposure.

Affiliations:

Canada, Taïwan

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000E32
to stream PascalFrancis, to step Curation: 001091

Links to Exploration step

Pascal:98-0196229

Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
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<term>Long term</term>
<term>Manganese</term>
<term>Nuclear magnetic resonance imaging</term>
<term>Parkinsonism</term>
<term>Poisoning</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Intoxication</term>
<term>Manganèse</term>
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<front><div type="abstract" xml:lang="en">We studied the long-term clinical course of five patients with chronic manganese intoxication. The mean scores of the King's College Hospital Rating Scale for Parkinson's disease increased from 15.0 ± 4.2 in 1987 to 28.3 ± 6.70 in 1991 and then to 38.1 ± 12.9 in 1995. The deterioration was most prominent in gait, rigidity, speed of foot tapping, and writing. Tissue concentrations of manganese in blood, urine, scalp hair, and pubic hair returned to normal. Follow-up MRIs did not show paramagnetic high-signal intensity on T1-weighted images. The data indicate that clinical progression in patients with manganese parkinsonism continues even 10 years after cessation of exposure.</div>
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	La maladie de Parkinson au Canada (serveur d'exploration)
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La maladie de Parkinson au Canada (serveur d'exploration)

Long-term progression in chronic manganism : Ten years of follow-up

Long-term progression in chronic manganism : Ten years of follow-up

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Descripteurs français

English descriptors

Abstract

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