Long-term progression in chronic manganism : Ten years of follow-up
Identifieur interne : 000E32 ( PascalFrancis/Corpus ); précédent : 000E31; suivant : 000E33Long-term progression in chronic manganism : Ten years of follow-up
Auteurs : C.-C. Huang ; N.-S. Chu ; C.-S. Lu ; R.-S. Chen ; D. B. CalneSource :
- Neurology [ 0028-3878 ] ; 1998.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
We studied the long-term clinical course of five patients with chronic manganese intoxication. The mean scores of the King's College Hospital Rating Scale for Parkinson's disease increased from 15.0 ± 4.2 in 1987 to 28.3 ± 6.70 in 1991 and then to 38.1 ± 12.9 in 1995. The deterioration was most prominent in gait, rigidity, speed of foot tapping, and writing. Tissue concentrations of manganese in blood, urine, scalp hair, and pubic hair returned to normal. Follow-up MRIs did not show paramagnetic high-signal intensity on T1-weighted images. The data indicate that clinical progression in patients with manganese parkinsonism continues even 10 years after cessation of exposure.
Notice en format standard (ISO 2709)
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Format Inist (serveur)
NO : | PASCAL 98-0196229 INIST |
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ET : | Long-term progression in chronic manganism : Ten years of follow-up |
AU : | HUANG (C.-C.); CHU (N.-S.); LU (C.-S.); CHEN (R.-S.); CALNE (D. B.) |
AF : | Department of Neurology, Chang Gung Memorial Hospital and Medical College/Taipei/Taïwan (1 aut., 2 aut., 3 aut., 4 aut.); Division of Neurology, Neurodegenerative Disorders Centre, University of British Columbia/Vancouver/Canada (5 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Neurology; ISSN 0028-3878; Coden NEURAI; Etats-Unis; Da. 1998; Vol. 50; No. 3; Pp. 698-700; Bibl. 20 ref. |
LA : | Anglais |
EA : | We studied the long-term clinical course of five patients with chronic manganese intoxication. The mean scores of the King's College Hospital Rating Scale for Parkinson's disease increased from 15.0 ± 4.2 in 1987 to 28.3 ± 6.70 in 1991 and then to 38.1 ± 12.9 in 1995. The deterioration was most prominent in gait, rigidity, speed of foot tapping, and writing. Tissue concentrations of manganese in blood, urine, scalp hair, and pubic hair returned to normal. Follow-up MRIs did not show paramagnetic high-signal intensity on T1-weighted images. The data indicate that clinical progression in patients with manganese parkinsonism continues even 10 years after cessation of exposure. |
CC : | 002B03L03 |
FD : | Intoxication; Manganèse; Chronique; Parkinsonisme; Imagerie RMN; Complication; Etude cas; Evolution; Long terme; Adulte; Manganisme |
FG : | Homme; Système nerveux pathologie; Trouble neurologique; Imagerie médicale |
ED : | Poisoning; Manganese; Chronic; Parkinsonism; Nuclear magnetic resonance imaging; Complication; Case study; Evolution; Long term; Adult |
EG : | Human; Nervous system diseases; Neurological disorder; Medical imagery |
GD : | Mangan |
SD : | Intoxicación; Manganeso; Crónico; Parkinson síndrome; Imageria RMN; Complicación; Estudio caso; Evolución; Largo plazo; Adulto |
LO : | INIST-6345.354000079243510220 |
ID : | 98-0196229 |
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Pascal:98-0196229Le document en format XML
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<front><div type="abstract" xml:lang="en">We studied the long-term clinical course of five patients with chronic manganese intoxication. The mean scores of the King's College Hospital Rating Scale for Parkinson's disease increased from 15.0 ± 4.2 in 1987 to 28.3 ± 6.70 in 1991 and then to 38.1 ± 12.9 in 1995. The deterioration was most prominent in gait, rigidity, speed of foot tapping, and writing. Tissue concentrations of manganese in blood, urine, scalp hair, and pubic hair returned to normal. Follow-up MRIs did not show paramagnetic high-signal intensity on T1-weighted images. The data indicate that clinical progression in patients with manganese parkinsonism continues even 10 years after cessation of exposure.</div>
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<ET>Long-term progression in chronic manganism : Ten years of follow-up</ET>
<AU>HUANG (C.-C.); CHU (N.-S.); LU (C.-S.); CHEN (R.-S.); CALNE (D. B.)</AU>
<AF>Department of Neurology, Chang Gung Memorial Hospital and Medical College/Taipei/Taïwan (1 aut., 2 aut., 3 aut., 4 aut.); Division of Neurology, Neurodegenerative Disorders Centre, University of British Columbia/Vancouver/Canada (5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
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<LA>Anglais</LA>
<EA>We studied the long-term clinical course of five patients with chronic manganese intoxication. The mean scores of the King's College Hospital Rating Scale for Parkinson's disease increased from 15.0 ± 4.2 in 1987 to 28.3 ± 6.70 in 1991 and then to 38.1 ± 12.9 in 1995. The deterioration was most prominent in gait, rigidity, speed of foot tapping, and writing. Tissue concentrations of manganese in blood, urine, scalp hair, and pubic hair returned to normal. Follow-up MRIs did not show paramagnetic high-signal intensity on T1-weighted images. The data indicate that clinical progression in patients with manganese parkinsonism continues even 10 years after cessation of exposure.</EA>
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