ParkinsonCanadaV1, Main, Exploration, bibRecordById, pubmed:18063471

Short-term variability in amplitude and motor topography of whole-body involuntary movements in Parkinson's disease dyskinesias and in Huntington's chorea

Identifieur interne : 002380 ( Main/Exploration ); précédent : 002379; suivant : 002381

Short-term variability in amplitude and motor topography of whole-body involuntary movements in Parkinson's disease dyskinesias and in Huntington's chorea

Auteurs : Alison Fenney [Canada] ; Mandar S. Jog [Canada] ; Christian Duval [Canada]

Source :

Clinical neurology and neurosurgery [ 0303-8467 ] ; 2008.

RBID : Pascal:08-0107040

Descripteurs français

Pascal (Inist)
- Mouvement involontaire, Maladie de Parkinson, Chorée de Huntington, Dyskinésie, Syndrome choréique, Pathologie du système nerveux, Court terme, Variabilité, Amplitude, Topographie, Mouvement corporel, Chirurgie.
Wicri :
- topic : Chirurgie.

English descriptors

KwdEn :
- Aged, Amplitude, Antiparkinson Agents (adverse effects), Arm, Body movement, Chorea, Cohort Studies, Dyskinesia, Dyskinesia, Drug-Induced (etiology), Dyskinesia, Drug-Induced (physiopathology), Female, Humans, Huntington Disease (physiopathology), Huntington disease, Involuntary movement, Leg, Levodopa (adverse effects), Male, Middle Aged, Nervous system diseases, Parkinson Disease (drug therapy), Parkinson Disease (physiopathology), Parkinson disease, Posture (physiology), Short term, Surgery, Thorax, Time Factors, Topography, Variability.
MESH :
- chemical , adverse effects : Antiparkinson Agents, Levodopa.
- drug therapy : Parkinson Disease.
- etiology : Dyskinesia, Drug-Induced.
- physiology : Posture.
- physiopathology : Dyskinesia, Drug-Induced, Huntington Disease, Parkinson Disease.
- Aged, Arm, Cohort Studies, Female, Humans, Leg, Male, Middle Aged, Thorax, Time Factors.

Abstract

Objectives: Clinical observations have noted variability in amplitude of levodopa-induced dyskinesias (LID) in Parkinson's disease (PD) and chorea in Huntington's disease (HD) during the day. However, no studies have examined whether both the amplitude and body location (motor topography) of whole-body involuntary movement (WBIM) varied over short periods of time (seconds or minutes), which may have a distinct and significant effect on how disruptive these WBIM may be. The present study quantified the variability of WBIM amplitude and motor topography in patients with PD having LID and in patients with HD having chorea. Patients and methods: WBIM was quantified using the MotionMonitor<^TM> magnetic motion tracker system. Five patients in each group were tested in two conditions: sitting and standing. Results: WBIM increased from sitting to standing, more so in choreic patients. WBIM varied from 17% to 102% of total WBIM amplitude. Chorea tended to present with greater variability than LID in absolute terms in the standing condition, but not when the mean WBIM amplitude was taken into consideration. Motor topography of WBIM also varied more in the HD group, but mostly in the seated condition where more limbs were free to move. Neither group expressed any laterality of involuntary movement, with amplitude being equally distributed on both sides of the body. Conclusion: Results show significant short-term variability in amplitude of chorea and LID, as well as, variability in location of these involuntary movements, illustrating the complexity of the adaptations required to live and be active with involuntary movements such as HD chorea or PD dyskinesias.

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Short-term variability in amplitude and motor topography of whole-body involuntary movements in Parkinson's disease dyskinesias and in Huntington's chorea</title>
<author><name sortKey="Fenney, Alison" sort="Fenney, Alison" uniqKey="Fenney A" first="Alison" last="Fenney">Alison Fenney</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Departement de Kinanthropologie, Université du Québec à Montréal, C.P 8888, Succursale Centre-Ville</s1>
<s2>Montréal, Québec, H3C 3P8</s2>
<s3>CAN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Montréal, Québec, H3C 3P8</wicri:noRegion>
<orgName type="university">Université du Québec à Montréal</orgName>
<placeName><settlement type="city">Montréal</settlement>
<region type="state">Québec</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jog, Mandar S" sort="Jog, Mandar S" uniqKey="Jog M" first="Mandar S." last="Jog">Mandar S. Jog</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Clinical Neurological Sciences, Movement Disorders Program, University of Western Ontario</s1>
<s2>London, Ont</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>London, Ont</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Duval, Christian" sort="Duval, Christian" uniqKey="Duval C" first="Christian" last="Duval">Christian Duval</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Departement de Kinanthropologie, Université du Québec à Montréal, C.P 8888, Succursale Centre-Ville</s1>
<s2>Montréal, Québec, H3C 3P8</s2>
<s3>CAN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Montréal, Québec, H3C 3P8</wicri:noRegion>
<orgName type="university">Université du Québec à Montréal</orgName>
<placeName><settlement type="city">Montréal</settlement>
<region type="state">Québec</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">08-0107040</idno>
<date when="2008">2008</date>
<idno type="stanalyst">PASCAL 08-0107040 INIST</idno>
<idno type="RBID">Pascal:08-0107040</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000672</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000638</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000515</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000515</idno>
<idno type="wicri:doubleKey">0303-8467:2008:Fenney A:short:term:variability</idno>
<idno type="wicri:Area/Main/Merge">002576</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:18063471</idno>
<idno type="wicri:Area/PubMed/Corpus">001002</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001002</idno>
<idno type="wicri:Area/PubMed/Curation">001002</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001002</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001002</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001002</idno>
<idno type="wicri:Area/Ncbi/Merge">000849</idno>
<idno type="wicri:Area/Ncbi/Curation">000849</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000849</idno>
<idno type="wicri:doubleKey">0303-8467:2008:Fenney A:short:term:variability</idno>
<idno type="wicri:Area/Main/Merge">002326</idno>
<idno type="wicri:Area/Main/Curation">002380</idno>
<idno type="wicri:Area/Main/Exploration">002380</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Short-term variability in amplitude and motor topography of whole-body involuntary movements in Parkinson's disease dyskinesias and in Huntington's chorea</title>
<author><name sortKey="Fenney, Alison" sort="Fenney, Alison" uniqKey="Fenney A" first="Alison" last="Fenney">Alison Fenney</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Departement de Kinanthropologie, Université du Québec à Montréal, C.P 8888, Succursale Centre-Ville</s1>
<s2>Montréal, Québec, H3C 3P8</s2>
<s3>CAN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Montréal, Québec, H3C 3P8</wicri:noRegion>
<orgName type="university">Université du Québec à Montréal</orgName>
<placeName><settlement type="city">Montréal</settlement>
<region type="state">Québec</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jog, Mandar S" sort="Jog, Mandar S" uniqKey="Jog M" first="Mandar S." last="Jog">Mandar S. Jog</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Clinical Neurological Sciences, Movement Disorders Program, University of Western Ontario</s1>
<s2>London, Ont</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>London, Ont</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Duval, Christian" sort="Duval, Christian" uniqKey="Duval C" first="Christian" last="Duval">Christian Duval</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Departement de Kinanthropologie, Université du Québec à Montréal, C.P 8888, Succursale Centre-Ville</s1>
<s2>Montréal, Québec, H3C 3P8</s2>
<s3>CAN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Montréal, Québec, H3C 3P8</wicri:noRegion>
<orgName type="university">Université du Québec à Montréal</orgName>
<placeName><settlement type="city">Montréal</settlement>
<region type="state">Québec</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Clinical neurology and neurosurgery</title>
<title level="j" type="abbreviated">Clin. neurol. neurosurg.</title>
<idno type="ISSN">0303-8467</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Clinical neurology and neurosurgery</title>
<title level="j" type="abbreviated">Clin. neurol. neurosurg.</title>
<idno type="ISSN">0303-8467</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Amplitude</term>
<term>Antiparkinson Agents (adverse effects)</term>
<term>Arm</term>
<term>Body movement</term>
<term>Chorea</term>
<term>Cohort Studies</term>
<term>Dyskinesia</term>
<term>Dyskinesia, Drug-Induced (etiology)</term>
<term>Dyskinesia, Drug-Induced (physiopathology)</term>
<term>Female</term>
<term>Humans</term>
<term>Huntington Disease (physiopathology)</term>
<term>Huntington disease</term>
<term>Involuntary movement</term>
<term>Leg</term>
<term>Levodopa (adverse effects)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Nervous system diseases</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson disease</term>
<term>Posture (physiology)</term>
<term>Short term</term>
<term>Surgery</term>
<term>Thorax</term>
<term>Time Factors</term>
<term>Topography</term>
<term>Variability</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antiparkinson Agents</term>
<term>Levodopa</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Dyskinesia, Drug-Induced</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Posture</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Dyskinesia, Drug-Induced</term>
<term>Huntington Disease</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Arm</term>
<term>Cohort Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Leg</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Thorax</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Mouvement involontaire</term>
<term>Maladie de Parkinson</term>
<term>Chorée de Huntington</term>
<term>Dyskinésie</term>
<term>Syndrome choréique</term>
<term>Pathologie du   système nerveux</term>
<term>Court terme</term>
<term>Variabilité</term>
<term>Amplitude</term>
<term>Topographie</term>
<term>Mouvement corporel</term>
<term>Chirurgie</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Chirurgie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Objectives: Clinical observations have noted variability in amplitude of levodopa-induced dyskinesias (LID) in Parkinson's disease (PD) and chorea in Huntington's disease (HD) during the day. However, no studies have examined whether both the amplitude and body location (motor topography) of whole-body involuntary movement (WBIM) varied over short periods of time (seconds or minutes), which may have a distinct and significant effect on how disruptive these WBIM may be. The present study quantified the variability of WBIM amplitude and motor topography in patients with PD having LID and in patients with HD having chorea. Patients and methods: WBIM was quantified using the MotionMonitor<<sup>TM</sup>
> magnetic motion tracker system. Five patients in each group were tested in two conditions: sitting and standing. Results: WBIM increased from sitting to standing, more so in choreic patients. WBIM varied from 17% to 102% of total WBIM amplitude. Chorea tended to present with greater variability than LID in absolute terms in the standing condition, but not when the mean WBIM amplitude was taken into consideration. Motor topography of WBIM also varied more in the HD group, but mostly in the seated condition where more limbs were free to move. Neither group expressed any laterality of involuntary movement, with amplitude being equally distributed on both sides of the body. Conclusion: Results show significant short-term variability in amplitude of chorea and LID, as well as, variability in location of these involuntary movements, illustrating the complexity of the adaptations required to live and be active with involuntary movements such as HD chorea or PD dyskinesias.</div>
</front>
</TEI>
<affiliations><list><country><li>Canada</li>
</country>
<region><li>Québec</li>
</region>
<settlement><li>Montréal</li>
</settlement>
<orgName><li>Université du Québec à Montréal</li>
</orgName>
</list>
<tree><country name="Canada"><region name="Québec"><name sortKey="Fenney, Alison" sort="Fenney, Alison" uniqKey="Fenney A" first="Alison" last="Fenney">Alison Fenney</name>
</region>
<name sortKey="Duval, Christian" sort="Duval, Christian" uniqKey="Duval C" first="Christian" last="Duval">Christian Duval</name>
<name sortKey="Jog, Mandar S" sort="Jog, Mandar S" uniqKey="Jog M" first="Mandar S." last="Jog">Mandar S. Jog</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002380 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002380 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Canada
   |area=    ParkinsonCanadaV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:08-0107040
   |texte=   Short-term variability in amplitude and motor topography of whole-body involuntary movements in Parkinson's disease dyskinesias and in Huntington's chorea
}}

This area was generated with Dilib version V0.6.29.
Data generation: Thu May 4 22:20:19 2017. Site generation: Fri Dec 23 23:17:26 2022

La maladie de Parkinson au Canada (serveur d'exploration)

Short-term variability in amplitude and motor topography of whole-body involuntary movements in Parkinson's disease dyskinesias and in Huntington's chorea

Short-term variability in amplitude and motor topography of whole-body involuntary movements in Parkinson's disease dyskinesias and in Huntington's chorea

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	La maladie de Parkinson au Canada (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.