La maladie de Parkinson au Canada (serveur d'exploration)

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Short-term variability in amplitude and motor topography of whole-body involuntary movements in Parkinson's disease dyskinesias and in Huntington's chorea.

Identifieur interne : 000849 ( Ncbi/Checkpoint ); précédent : 000848; suivant : 000850

Short-term variability in amplitude and motor topography of whole-body involuntary movements in Parkinson's disease dyskinesias and in Huntington's chorea.

Auteurs : Alison Fenney [Canada] ; Mandar S. Jog ; Christian Duval

Source :

RBID : pubmed:18063471

English descriptors

Abstract

Clinical observations have noted variability in amplitude of levodopa-induced dyskinesias (LID) in Parkinson's disease (PD) and chorea in Huntington's disease (HD) during the day. However, no studies have examined whether both the amplitude and body location (motor topography) of whole-body involuntary movement (WBIM) varied over short periods of time (seconds or minutes), which may have a distinct and significant effect on how disruptive these WBIM may be. The present study quantified the variability of WBIM amplitude and motor topography in patients with PD having LID and in patients with HD having chorea.

DOI: 10.1016/j.clineuro.2007.10.010
PubMed: 18063471


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pubmed:18063471

Le document en format XML

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<term>Dyskinesia, Drug-Induced (etiology)</term>
<term>Dyskinesia, Drug-Induced (physiopathology)</term>
<term>Female</term>
<term>Humans</term>
<term>Huntington Disease (physiopathology)</term>
<term>Leg</term>
<term>Levodopa (adverse effects)</term>
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<term>Middle Aged</term>
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<term>Parkinson Disease</term>
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