Immunological characteristics of human mesenchymal stem cells and multipotent adult progenitor cells
Identifieur interne : 000315 ( Main/Merge ); précédent : 000314; suivant : 000316Immunological characteristics of human mesenchymal stem cells and multipotent adult progenitor cells
Auteurs : Sandra A. Jacobs [Belgique] ; Valerie D. Roobrouck [Belgique] ; Catherine M. Verfaillie [Belgique] ; Stefaan W. Van Gool [Belgique]Source :
- Immunology and Cell Biology [ 0818-9641 ] ; 2013.
Abstract
Somatic, also termed adult, stem cells are highly attractive biomedical cell candidates because of their extensive replication potential and functional multilineage differentiation capacity. They can be used for drug and toxicity screenings in preclinical studies, as
Url:
DOI: 10.1038/icb.2012.64
PubMed: 23295415
PubMed Central: 3540326
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Immunological characteristics of human mesenchymal stem cells and multipotent adult progenitor cells</title><author><name sortKey="Jacobs, Sandra A" sort="Jacobs, Sandra A" uniqKey="Jacobs S" first="Sandra A" last="Jacobs">Sandra A. Jacobs</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Microbiology and Immunology, Laboratory of Pediatric Immunology, KU Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Roobrouck, Valerie D" sort="Roobrouck, Valerie D" uniqKey="Roobrouck V" first="Valerie D" last="Roobrouck">Valerie D. Roobrouck</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Development and Regeneration, Stem Cell Institute Leuven, KU Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Verfaillie, Catherine M" sort="Verfaillie, Catherine M" uniqKey="Verfaillie C" first="Catherine M" last="Verfaillie">Catherine M. Verfaillie</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Development and Regeneration, Stem Cell Institute Leuven, KU Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Gool, Stefaan W" sort="Van Gool, Stefaan W" uniqKey="Van Gool S" first="Stefaan W" last="Van Gool">Stefaan W. Van Gool</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Microbiology and Immunology, Laboratory of Pediatric Immunology, KU Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23295415</idno><idno type="pmc">3540326</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540326</idno><idno type="RBID">PMC:3540326</idno><idno type="doi">10.1038/icb.2012.64</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000007</idno><idno type="wicri:Area/Pmc/Curation">000007</idno><idno type="wicri:Area/Pmc/Checkpoint">000268</idno><idno type="wicri:Area/Ncbi/Merge">000160</idno><idno type="wicri:Area/Ncbi/Curation">000160</idno><idno type="wicri:Area/Ncbi/Checkpoint">000160</idno><idno type="wicri:doubleKey">0818-9641:2013:Jacobs S:immunological:characteristics:of</idno><idno type="wicri:Area/Main/Merge">000315</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Immunological characteristics of human mesenchymal stem cells and multipotent adult progenitor cells</title><author><name sortKey="Jacobs, Sandra A" sort="Jacobs, Sandra A" uniqKey="Jacobs S" first="Sandra A" last="Jacobs">Sandra A. Jacobs</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Microbiology and Immunology, Laboratory of Pediatric Immunology, KU Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Roobrouck, Valerie D" sort="Roobrouck, Valerie D" uniqKey="Roobrouck V" first="Valerie D" last="Roobrouck">Valerie D. Roobrouck</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Development and Regeneration, Stem Cell Institute Leuven, KU Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Verfaillie, Catherine M" sort="Verfaillie, Catherine M" uniqKey="Verfaillie C" first="Catherine M" last="Verfaillie">Catherine M. Verfaillie</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Development and Regeneration, Stem Cell Institute Leuven, KU Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Gool, Stefaan W" sort="Van Gool, Stefaan W" uniqKey="Van Gool S" first="Stefaan W" last="Van Gool">Stefaan W. Van Gool</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Microbiology and Immunology, Laboratory of Pediatric Immunology, KU Leuven</institution>, Leuven,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Immunology and Cell Biology</title><idno type="ISSN">0818-9641</idno><idno type="eISSN">1440-1711</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Somatic, also termed adult, stem cells are highly attractive biomedical cell candidates because of their extensive replication potential and functional multilineage differentiation capacity. They can be used for drug and toxicity screenings in preclinical studies, as <italic>in vitro</italic> model to study differentiation or for regenerative medicine to aid in the repair of tissues or replace tissues that are lost upon disease, injury or ageing. Multipotent adult progenitor cells (MAPCs) and mesenchymal stem cells (MSCs) are two types of adult stem cells derived from bone marrow that are currently being used clinically for tissue regeneration and for their immunomodulatory and trophic effects. This review will give an overview of the phenotypic and functional differences between human MAPCs and MSCs, with a strong emphasis on their immunological characteristics. 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F" uniqKey="Buron F">F Buron</name></author><author><name sortKey="Perrin, H" uniqKey="Perrin H">H Perrin</name></author><author><name sortKey="Malcus, C" uniqKey="Malcus C">C Malcus</name></author><author><name sortKey="Hequet, O" uniqKey="Hequet O">O Hequet</name></author><author><name sortKey="Thaunat, O" uniqKey="Thaunat O">O Thaunat</name></author><author><name sortKey="Kholopp Sarda, Mn" uniqKey="Kholopp Sarda M">MN Kholopp-Sarda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eggenhofer, E" uniqKey="Eggenhofer E">E Eggenhofer</name></author><author><name sortKey="Steinmann, Jf" uniqKey="Steinmann J">JF Steinmann</name></author><author><name sortKey="Renner, P" uniqKey="Renner P">P Renner</name></author><author><name sortKey="Slowik, P" uniqKey="Slowik P">P Slowik</name></author><author><name sortKey="Piso, P" uniqKey="Piso P">P Piso</name></author><author><name sortKey="Geissler, Ek" uniqKey="Geissler E">EK Geissler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Inoue, S" uniqKey="Inoue S">S Inoue</name></author><author><name sortKey="Popp, Fc" uniqKey="Popp F">FC Popp</name></author><author><name sortKey="Koehl, Ge" uniqKey="Koehl G">GE Koehl</name></author><author><name sortKey="Piso, P" uniqKey="Piso P">P Piso</name></author><author><name sortKey="Schlitt, Hj" uniqKey="Schlitt H">HJ Schlitt</name></author><author><name sortKey="Geissler, Ek" uniqKey="Geissler E">EK Geissler</name></author></analytic></biblStruct></listBibl></div1></back></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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