Feasible usage of ABO incompatible grafts in living donor liver transplantation
Identifieur interne : 000453 ( Pmc/Corpus ); précédent : 000452; suivant : 000454Feasible usage of ABO incompatible grafts in living donor liver transplantation
Auteurs : Toru Ikegami ; Tomoharu Yoshizumi ; Yuji Soejima ; Hideaki Uchiyama ; Ken Shirabe ; Yoshihiko MaeharaSource :
- Hepatobiliary Surgery and Nutrition [ 2304-3881 ] ; 2016.
Abstract
The use of ABO incompatible (ABOi) graft in living donor liver transplantation (LDLT) has not been an established procedure worldwide.
Four hundred and eight adult LDLTs, using ABOi (n=19) and non-ABOi (n=389) grafts, were performed as a single center experience.
In ABOi-LDLT group (n=19), median isoagglutinin titer before plasma exchange (PE) at LDLT and after LDLT (max) was ×256, ×32 and ×32, respectively. Rituximab was given at 21.8±6.1 days before LDLT and PE was performed 3.7±1.6 times. Although ABOi-LDLTs had increased rate of splenectomy (89.4%
ABOi-LDLT could be safely performed, especially under rituximab-based protocol.
Url:
DOI: 10.3978/j.issn.2304-3881.2015.06.02
PubMed: 27115002
PubMed Central: 4824747
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