Influence of 360-degree enhanced optic edge design of a hydrophilic acrylic intraocular lens on posterior capsule opacification
Identifieur interne : 000B85 ( PascalFrancis/Corpus ); précédent : 000B84; suivant : 000B86Influence of 360-degree enhanced optic edge design of a hydrophilic acrylic intraocular lens on posterior capsule opacification
Auteurs : Yutaro Nishi ; Tanja M. Rabsilber ; Il-Joo Limberger ; Andreas J. Reuland ; Gerd U. AuffarthSource :
- Journal of cataract and refractive surgery [ 0886-3350 ] ; 2007.
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English descriptors
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Abstract
PURPOSE: To compare the rate of posterior capsule opacification (PCO) with the single-piece hydrophilic acrylic foldable Rayner Centerflex 570H intraocular lens (IOL), which has a sharp optic edge design excluding the optic-haptic junction, and the Rayner C-flex 570C IOL, which has an improved 360-degree sharp edge. SETTING: Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany. METHODS: As part of a multicenter U.S. Food and Drug Administration (FDA) study, 42 patients who had implantation of a C-flex IOL in 1 eye after uneventful phacoemulsification were enrolled. six and 12 months postoperatively, PCO was evaluated by retroillumination photographs using Evaluation of Posterior Capsule Opacification (EPCO) 2000 image-analysis software. The data were then compared with those in a matched group of patients with a Centerflex IOL who participated in a previous FDA study. RESULTS: The mean age of the patients with the C-flex IOL was 71.5 years + 8.2 (SD) There was a statistically significant difference in EPCO scores between the C-flex group and Centerflex group. Six months after surgery, the mean EPCO value (total IOL optic) was 0.07 + 0.17 in the C-flex group (n = 37) and 0.20 ± 0.20 in the Centerflex group (n = 36) (P<.01, Wilcoxon test). By 12 months, the mean had increased to 0,16 + 0.20 in the C-flex group (n = 37) and 0.35 + 0.22 in the Centerflex group (n = 31) (P<.01, Wilcoxon test). CONCLUSIONS: The C-flex lOLs showed good functional results and significantly lower PCO formation than the earlier model Centerflex IOL. The enhanced edge of the C-flex IOL seemed to improve PCO prevention clinically.
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NO : | PASCAL 07-0121162 INIST |
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ET : | Influence of 360-degree enhanced optic edge design of a hydrophilic acrylic intraocular lens on posterior capsule opacification |
AU : | NISHI (Yutaro); RABSILBER (Tanja M.); LIMBERGER (Il-Joo); REULAND (Andreas J.); AUFFARTH (Gerd U.) |
AF : | International Vision Correction Research Centre, Department of Ophthalmology, University of Heidelberg/Heidelberg/Allemagne (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Journal of cataract and refractive surgery; ISSN 0886-3350; Coden JCSUEV; Etats-Unis; Da. 2007; Vol. 33; No. 2; Pp. 227-231; Bibl. 29 ref. |
LA : | Anglais |
EA : | PURPOSE: To compare the rate of posterior capsule opacification (PCO) with the single-piece hydrophilic acrylic foldable Rayner Centerflex 570H intraocular lens (IOL), which has a sharp optic edge design excluding the optic-haptic junction, and the Rayner C-flex 570C IOL, which has an improved 360-degree sharp edge. SETTING: Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany. METHODS: As part of a multicenter U.S. Food and Drug Administration (FDA) study, 42 patients who had implantation of a C-flex IOL in 1 eye after uneventful phacoemulsification were enrolled. six and 12 months postoperatively, PCO was evaluated by retroillumination photographs using Evaluation of Posterior Capsule Opacification (EPCO) 2000 image-analysis software. The data were then compared with those in a matched group of patients with a Centerflex IOL who participated in a previous FDA study. RESULTS: The mean age of the patients with the C-flex IOL was 71.5 years + 8.2 (SD) There was a statistically significant difference in EPCO scores between the C-flex group and Centerflex group. Six months after surgery, the mean EPCO value (total IOL optic) was 0.07 + 0.17 in the C-flex group (n = 37) and 0.20 ± 0.20 in the Centerflex group (n = 36) (P<.01, Wilcoxon test). By 12 months, the mean had increased to 0,16 + 0.20 in the C-flex group (n = 37) and 0.35 + 0.22 in the Centerflex group (n = 31) (P<.01, Wilcoxon test). CONCLUSIONS: The C-flex lOLs showed good functional results and significantly lower PCO formation than the earlier model Centerflex IOL. The enhanced edge of the C-flex IOL seemed to improve PCO prevention clinically. |
CC : | 002B25B |
FD : | Influence; Optique; Bord; Conception; Hydrophilie; Acrylique dérivé polymère; Postérieur; Capsule; Opacification; Chirurgie; Ophtalmologie; Traitement |
ED : | Influence; Optics; Edge; Design; Hydrophily; Acrylic polymer; Posterior; Capsule; Opacification; Surgery; Ophthalmology; Treatment |
SD : | Influencia; Optica; Borde; Diseño; Hidrofilia; Acrilico derivado polímero; Posterior; Cápsula; Opacificación; Cirugía; Oftalmología; Tratamiento |
LO : | INIST-20937.354000145429490090 |
ID : | 07-0121162 |
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<front><div type="abstract" xml:lang="en">PURPOSE: To compare the rate of posterior capsule opacification (PCO) with the single-piece hydrophilic acrylic foldable Rayner Centerflex 570H intraocular lens (IOL), which has a sharp optic edge design excluding the optic-haptic junction, and the Rayner C-flex 570C IOL, which has an improved 360-degree sharp edge. SETTING: Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany. METHODS: As part of a multicenter U.S. Food and Drug Administration (FDA) study, 42 patients who had implantation of a C-flex IOL in 1 eye after uneventful phacoemulsification were enrolled. six and 12 months postoperatively, PCO was evaluated by retroillumination photographs using Evaluation of Posterior Capsule Opacification (EPCO) 2000 image-analysis software. The data were then compared with those in a matched group of patients with a Centerflex IOL who participated in a previous FDA study. RESULTS: The mean age of the patients with the C-flex IOL was 71.5 years + 8.2 (SD) There was a statistically significant difference in EPCO scores between the C-flex group and Centerflex group. Six months after surgery, the mean EPCO value (total IOL optic) was 0.07 + 0.17 in the C-flex group (n = 37) and 0.20 ± 0.20 in the Centerflex group (n = 36) (P<.01, Wilcoxon test). By 12 months, the mean had increased to 0,16 + 0.20 in the C-flex group (n = 37) and 0.35 + 0.22 in the Centerflex group (n = 31) (P<.01, Wilcoxon test). CONCLUSIONS: The C-flex lOLs showed good functional results and significantly lower PCO formation than the earlier model Centerflex IOL. The enhanced edge of the C-flex IOL seemed to improve PCO prevention clinically.</div>
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<ET>Influence of 360-degree enhanced optic edge design of a hydrophilic acrylic intraocular lens on posterior capsule opacification</ET>
<AU>NISHI (Yutaro); RABSILBER (Tanja M.); LIMBERGER (Il-Joo); REULAND (Andreas J.); AUFFARTH (Gerd U.)</AU>
<AF>International Vision Correction Research Centre, Department of Ophthalmology, University of Heidelberg/Heidelberg/Allemagne (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Journal of cataract and refractive surgery; ISSN 0886-3350; Coden JCSUEV; Etats-Unis; Da. 2007; Vol. 33; No. 2; Pp. 227-231; Bibl. 29 ref.</SO>
<LA>Anglais</LA>
<EA>PURPOSE: To compare the rate of posterior capsule opacification (PCO) with the single-piece hydrophilic acrylic foldable Rayner Centerflex 570H intraocular lens (IOL), which has a sharp optic edge design excluding the optic-haptic junction, and the Rayner C-flex 570C IOL, which has an improved 360-degree sharp edge. SETTING: Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany. METHODS: As part of a multicenter U.S. Food and Drug Administration (FDA) study, 42 patients who had implantation of a C-flex IOL in 1 eye after uneventful phacoemulsification were enrolled. six and 12 months postoperatively, PCO was evaluated by retroillumination photographs using Evaluation of Posterior Capsule Opacification (EPCO) 2000 image-analysis software. The data were then compared with those in a matched group of patients with a Centerflex IOL who participated in a previous FDA study. RESULTS: The mean age of the patients with the C-flex IOL was 71.5 years + 8.2 (SD) There was a statistically significant difference in EPCO scores between the C-flex group and Centerflex group. Six months after surgery, the mean EPCO value (total IOL optic) was 0.07 + 0.17 in the C-flex group (n = 37) and 0.20 ± 0.20 in the Centerflex group (n = 36) (P<.01, Wilcoxon test). By 12 months, the mean had increased to 0,16 + 0.20 in the C-flex group (n = 37) and 0.35 + 0.22 in the Centerflex group (n = 31) (P<.01, Wilcoxon test). CONCLUSIONS: The C-flex lOLs showed good functional results and significantly lower PCO formation than the earlier model Centerflex IOL. The enhanced edge of the C-flex IOL seemed to improve PCO prevention clinically.</EA>
<CC>002B25B</CC>
<FD>Influence; Optique; Bord; Conception; Hydrophilie; Acrylique dérivé polymère; Postérieur; Capsule; Opacification; Chirurgie; Ophtalmologie; Traitement</FD>
<ED>Influence; Optics; Edge; Design; Hydrophily; Acrylic polymer; Posterior; Capsule; Opacification; Surgery; Ophthalmology; Treatment</ED>
<SD>Influencia; Optica; Borde; Diseño; Hidrofilia; Acrilico derivado polímero; Posterior; Cápsula; Opacificación; Cirugía; Oftalmología; Tratamiento</SD>
<LO>INIST-20937.354000145429490090</LO>
<ID>07-0121162</ID>
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