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Influence of 360-degree enhanced optic edge design of a hydrophilic acrylic intraocular lens on posterior capsule opacification

Identifieur interne : 000B85 ( PascalFrancis/Corpus ); précédent : 000B84; suivant : 000B86

Influence of 360-degree enhanced optic edge design of a hydrophilic acrylic intraocular lens on posterior capsule opacification

Auteurs : Yutaro Nishi ; Tanja M. Rabsilber ; Il-Joo Limberger ; Andreas J. Reuland ; Gerd U. Auffarth

Source :

RBID : Pascal:07-0121162

Descripteurs français

English descriptors

Abstract

PURPOSE: To compare the rate of posterior capsule opacification (PCO) with the single-piece hydrophilic acrylic foldable Rayner Centerflex 570H intraocular lens (IOL), which has a sharp optic edge design excluding the optic-haptic junction, and the Rayner C-flex 570C IOL, which has an improved 360-degree sharp edge. SETTING: Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany. METHODS: As part of a multicenter U.S. Food and Drug Administration (FDA) study, 42 patients who had implantation of a C-flex IOL in 1 eye after uneventful phacoemulsification were enrolled. six and 12 months postoperatively, PCO was evaluated by retroillumination photographs using Evaluation of Posterior Capsule Opacification (EPCO) 2000 image-analysis software. The data were then compared with those in a matched group of patients with a Centerflex IOL who participated in a previous FDA study. RESULTS: The mean age of the patients with the C-flex IOL was 71.5 years + 8.2 (SD) There was a statistically significant difference in EPCO scores between the C-flex group and Centerflex group. Six months after surgery, the mean EPCO value (total IOL optic) was 0.07 + 0.17 in the C-flex group (n = 37) and 0.20 ± 0.20 in the Centerflex group (n = 36) (P<.01, Wilcoxon test). By 12 months, the mean had increased to 0,16 + 0.20 in the C-flex group (n = 37) and 0.35 + 0.22 in the Centerflex group (n = 31) (P<.01, Wilcoxon test). CONCLUSIONS: The C-flex lOLs showed good functional results and significantly lower PCO formation than the earlier model Centerflex IOL. The enhanced edge of the C-flex IOL seemed to improve PCO prevention clinically.

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Pour connaître la documentation sur le format Inist Standard.

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A02 01      @0 JCSUEV
A03   1    @0 J. cataract refractive surg.
A05       @2 33
A06       @2 2
A08 01  1  ENG  @1 Influence of 360-degree enhanced optic edge design of a hydrophilic acrylic intraocular lens on posterior capsule opacification
A11 01  1    @1 NISHI (Yutaro)
A11 02  1    @1 RABSILBER (Tanja M.)
A11 03  1    @1 LIMBERGER (Il-Joo)
A11 04  1    @1 REULAND (Andreas J.)
A11 05  1    @1 AUFFARTH (Gerd U.)
A14 01      @1 International Vision Correction Research Centre, Department of Ophthalmology, University of Heidelberg @2 Heidelberg @3 DEU @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut.
A20       @1 227-231
A21       @1 2007
A23 01      @0 ENG
A43 01      @1 INIST @2 20937 @5 354000145429490090
A44       @0 0000 @1 © 2007 INIST-CNRS. All rights reserved.
A45       @0 29 ref.
A47 01  1    @0 07-0121162
A60       @1 P
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A64 01  1    @0 Journal of cataract and refractive surgery
A66 01      @0 USA
C01 01    ENG  @0 PURPOSE: To compare the rate of posterior capsule opacification (PCO) with the single-piece hydrophilic acrylic foldable Rayner Centerflex 570H intraocular lens (IOL), which has a sharp optic edge design excluding the optic-haptic junction, and the Rayner C-flex 570C IOL, which has an improved 360-degree sharp edge. SETTING: Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany. METHODS: As part of a multicenter U.S. Food and Drug Administration (FDA) study, 42 patients who had implantation of a C-flex IOL in 1 eye after uneventful phacoemulsification were enrolled. six and 12 months postoperatively, PCO was evaluated by retroillumination photographs using Evaluation of Posterior Capsule Opacification (EPCO) 2000 image-analysis software. The data were then compared with those in a matched group of patients with a Centerflex IOL who participated in a previous FDA study. RESULTS: The mean age of the patients with the C-flex IOL was 71.5 years + 8.2 (SD) There was a statistically significant difference in EPCO scores between the C-flex group and Centerflex group. Six months after surgery, the mean EPCO value (total IOL optic) was 0.07 + 0.17 in the C-flex group (n = 37) and 0.20 ± 0.20 in the Centerflex group (n = 36) (P<.01, Wilcoxon test). By 12 months, the mean had increased to 0,16 + 0.20 in the C-flex group (n = 37) and 0.35 + 0.22 in the Centerflex group (n = 31) (P<.01, Wilcoxon test). CONCLUSIONS: The C-flex lOLs showed good functional results and significantly lower PCO formation than the earlier model Centerflex IOL. The enhanced edge of the C-flex IOL seemed to improve PCO prevention clinically.
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C03 08  X  SPA  @0 Cápsula @5 12
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Format Inist (serveur)

NO : PASCAL 07-0121162 INIST
ET : Influence of 360-degree enhanced optic edge design of a hydrophilic acrylic intraocular lens on posterior capsule opacification
AU : NISHI (Yutaro); RABSILBER (Tanja M.); LIMBERGER (Il-Joo); REULAND (Andreas J.); AUFFARTH (Gerd U.)
AF : International Vision Correction Research Centre, Department of Ophthalmology, University of Heidelberg/Heidelberg/Allemagne (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.)
DT : Publication en série; Niveau analytique
SO : Journal of cataract and refractive surgery; ISSN 0886-3350; Coden JCSUEV; Etats-Unis; Da. 2007; Vol. 33; No. 2; Pp. 227-231; Bibl. 29 ref.
LA : Anglais
EA : PURPOSE: To compare the rate of posterior capsule opacification (PCO) with the single-piece hydrophilic acrylic foldable Rayner Centerflex 570H intraocular lens (IOL), which has a sharp optic edge design excluding the optic-haptic junction, and the Rayner C-flex 570C IOL, which has an improved 360-degree sharp edge. SETTING: Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany. METHODS: As part of a multicenter U.S. Food and Drug Administration (FDA) study, 42 patients who had implantation of a C-flex IOL in 1 eye after uneventful phacoemulsification were enrolled. six and 12 months postoperatively, PCO was evaluated by retroillumination photographs using Evaluation of Posterior Capsule Opacification (EPCO) 2000 image-analysis software. The data were then compared with those in a matched group of patients with a Centerflex IOL who participated in a previous FDA study. RESULTS: The mean age of the patients with the C-flex IOL was 71.5 years + 8.2 (SD) There was a statistically significant difference in EPCO scores between the C-flex group and Centerflex group. Six months after surgery, the mean EPCO value (total IOL optic) was 0.07 + 0.17 in the C-flex group (n = 37) and 0.20 ± 0.20 in the Centerflex group (n = 36) (P<.01, Wilcoxon test). By 12 months, the mean had increased to 0,16 + 0.20 in the C-flex group (n = 37) and 0.35 + 0.22 in the Centerflex group (n = 31) (P<.01, Wilcoxon test). CONCLUSIONS: The C-flex lOLs showed good functional results and significantly lower PCO formation than the earlier model Centerflex IOL. The enhanced edge of the C-flex IOL seemed to improve PCO prevention clinically.
CC : 002B25B
FD : Influence; Optique; Bord; Conception; Hydrophilie; Acrylique dérivé polymère; Postérieur; Capsule; Opacification; Chirurgie; Ophtalmologie; Traitement
ED : Influence; Optics; Edge; Design; Hydrophily; Acrylic polymer; Posterior; Capsule; Opacification; Surgery; Ophthalmology; Treatment
SD : Influencia; Optica; Borde; Diseño; Hidrofilia; Acrilico derivado polímero; Posterior; Cápsula; Opacificación; Cirugía; Oftalmología; Tratamiento
LO : INIST-20937.354000145429490090
ID : 07-0121162

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Pascal:07-0121162

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<div type="abstract" xml:lang="en">PURPOSE: To compare the rate of posterior capsule opacification (PCO) with the single-piece hydrophilic acrylic foldable Rayner Centerflex 570H intraocular lens (IOL), which has a sharp optic edge design excluding the optic-haptic junction, and the Rayner C-flex 570C IOL, which has an improved 360-degree sharp edge. SETTING: Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany. METHODS: As part of a multicenter U.S. Food and Drug Administration (FDA) study, 42 patients who had implantation of a C-flex IOL in 1 eye after uneventful phacoemulsification were enrolled. six and 12 months postoperatively, PCO was evaluated by retroillumination photographs using Evaluation of Posterior Capsule Opacification (EPCO) 2000 image-analysis software. The data were then compared with those in a matched group of patients with a Centerflex IOL who participated in a previous FDA study. RESULTS: The mean age of the patients with the C-flex IOL was 71.5 years + 8.2 (SD) There was a statistically significant difference in EPCO scores between the C-flex group and Centerflex group. Six months after surgery, the mean EPCO value (total IOL optic) was 0.07 + 0.17 in the C-flex group (n = 37) and 0.20 ± 0.20 in the Centerflex group (n = 36) (P<.01, Wilcoxon test). By 12 months, the mean had increased to 0,16 + 0.20 in the C-flex group (n = 37) and 0.35 + 0.22 in the Centerflex group (n = 31) (P<.01, Wilcoxon test). CONCLUSIONS: The C-flex lOLs showed good functional results and significantly lower PCO formation than the earlier model Centerflex IOL. The enhanced edge of the C-flex IOL seemed to improve PCO prevention clinically.</div>
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<s5>03</s5>
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<s5>03</s5>
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<s5>03</s5>
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<s5>05</s5>
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<fC03 i1="03" i2="X" l="ENG">
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<s5>05</s5>
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<s5>05</s5>
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<fC03 i1="04" i2="X" l="FRE">
<s0>Conception</s0>
<s5>06</s5>
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<s0>Design</s0>
<s5>06</s5>
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<s5>06</s5>
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<s0>Hydrophilie</s0>
<s5>08</s5>
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<s5>08</s5>
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<s5>08</s5>
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<s2>NK</s2>
<s5>09</s5>
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<s0>Acrylic polymer</s0>
<s2>NK</s2>
<s5>09</s5>
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<s0>Acrilico derivado polímero</s0>
<s2>NK</s2>
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<s5>11</s5>
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<s5>12</s5>
</fC03>
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<s0>Cápsula</s0>
<s5>12</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE">
<s0>Opacification</s0>
<s5>14</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG">
<s0>Opacification</s0>
<s5>14</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA">
<s0>Opacificación</s0>
<s5>14</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE">
<s0>Chirurgie</s0>
<s5>15</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG">
<s0>Surgery</s0>
<s5>15</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA">
<s0>Cirugía</s0>
<s5>15</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE">
<s0>Ophtalmologie</s0>
<s5>17</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG">
<s0>Ophthalmology</s0>
<s5>17</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA">
<s0>Oftalmología</s0>
<s5>17</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE">
<s0>Traitement</s0>
<s5>25</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG">
<s0>Treatment</s0>
<s5>25</s5>
</fC03>
<fC03 i1="12" i2="X" l="SPA">
<s0>Tratamiento</s0>
<s5>25</s5>
</fC03>
<fN21>
<s1>078</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
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<server>
<NO>PASCAL 07-0121162 INIST</NO>
<ET>Influence of 360-degree enhanced optic edge design of a hydrophilic acrylic intraocular lens on posterior capsule opacification</ET>
<AU>NISHI (Yutaro); RABSILBER (Tanja M.); LIMBERGER (Il-Joo); REULAND (Andreas J.); AUFFARTH (Gerd U.)</AU>
<AF>International Vision Correction Research Centre, Department of Ophthalmology, University of Heidelberg/Heidelberg/Allemagne (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Journal of cataract and refractive surgery; ISSN 0886-3350; Coden JCSUEV; Etats-Unis; Da. 2007; Vol. 33; No. 2; Pp. 227-231; Bibl. 29 ref.</SO>
<LA>Anglais</LA>
<EA>PURPOSE: To compare the rate of posterior capsule opacification (PCO) with the single-piece hydrophilic acrylic foldable Rayner Centerflex 570H intraocular lens (IOL), which has a sharp optic edge design excluding the optic-haptic junction, and the Rayner C-flex 570C IOL, which has an improved 360-degree sharp edge. SETTING: Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany. METHODS: As part of a multicenter U.S. Food and Drug Administration (FDA) study, 42 patients who had implantation of a C-flex IOL in 1 eye after uneventful phacoemulsification were enrolled. six and 12 months postoperatively, PCO was evaluated by retroillumination photographs using Evaluation of Posterior Capsule Opacification (EPCO) 2000 image-analysis software. The data were then compared with those in a matched group of patients with a Centerflex IOL who participated in a previous FDA study. RESULTS: The mean age of the patients with the C-flex IOL was 71.5 years + 8.2 (SD) There was a statistically significant difference in EPCO scores between the C-flex group and Centerflex group. Six months after surgery, the mean EPCO value (total IOL optic) was 0.07 + 0.17 in the C-flex group (n = 37) and 0.20 ± 0.20 in the Centerflex group (n = 36) (P<.01, Wilcoxon test). By 12 months, the mean had increased to 0,16 + 0.20 in the C-flex group (n = 37) and 0.35 + 0.22 in the Centerflex group (n = 31) (P<.01, Wilcoxon test). CONCLUSIONS: The C-flex lOLs showed good functional results and significantly lower PCO formation than the earlier model Centerflex IOL. The enhanced edge of the C-flex IOL seemed to improve PCO prevention clinically.</EA>
<CC>002B25B</CC>
<FD>Influence; Optique; Bord; Conception; Hydrophilie; Acrylique dérivé polymère; Postérieur; Capsule; Opacification; Chirurgie; Ophtalmologie; Traitement</FD>
<ED>Influence; Optics; Edge; Design; Hydrophily; Acrylic polymer; Posterior; Capsule; Opacification; Surgery; Ophthalmology; Treatment</ED>
<SD>Influencia; Optica; Borde; Diseño; Hidrofilia; Acrilico derivado polímero; Posterior; Cápsula; Opacificación; Cirugía; Oftalmología; Tratamiento</SD>
<LO>INIST-20937.354000145429490090</LO>
<ID>07-0121162</ID>
</server>
</inist>
</record>

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