HapticV1, PascalFrancis, Corpus, bibRecord, 000B64

Influence of three-piece and single-piece designs of two sharp-edge optic hydrophobic acrylic intraocular lenses on the prevention of posterior capsule opacification : a prospective, randomised, long-term clinical trial

Identifieur interne : 000B64 ( PascalFrancis/Corpus ); précédent : 000B63; suivant : 000B65

Influence of three-piece and single-piece designs of two sharp-edge optic hydrophobic acrylic intraocular lenses on the prevention of posterior capsule opacification : a prospective, randomised, long-term clinical trial

Auteurs : Redo Zemaitiene ; Vytautas Jasinskas ; Gerd U. Auffarth

Source :

British journal of ophthalmology [ 0007-1161 ] ; 2007.

RBID : Pascal:07-0207414

Descripteurs français

Pascal (Inist)
- Influence, Conception, Bord, Optique, Lentille intraoculaire, Prévention, Postérieur, Capsule, Opacification, Prospective, Randomisation, Long terme, Essai clinique, Ophtalmologie, Traitement.

English descriptors

KwdEn :
- Capsule, Clinical trial, Design, Edge, Influence, Intraocular lens, Long term, Opacification, Ophthalmology, Optics, Posterior, Prevention, Prospective, Randomization, Treatment.

Abstract

Background: Posterior capsule opacification (PCO) is still a major long-term complication of modern cataract surgery. We evaluated the impact of sharp-edged intraocular lenses (lOLs) with different haptic designs made from the same hydrophobic acrylic material on posterior and anterior lens capsule opacification. Setting: Eye clinic of Kaunas University of Medicine, Lithuania. Prospective randomised clinical study. Methods: Seventy-four eyes of 74 patients scheduled for cataract surgery were included in a prospective randomised clinical study. Thirty-seven eyes of 37 patients received a three-piece acrylic hydrophobic (AcrySof, MA30BA, Alcon) IOL; and thirty-seven eyes of 37 patients received a one-piece acrylic hydrophobic (AcrySof, SA30AL, Alcon) IOL. Visual acuity, anterior capsule opacification (ACO), capsular folds, capsulorrhexis/optic overlapping and posterior capsule opacification (PCO) were evaluated. ACO was assessed subjectively. PCO values in the entire IOL optic area and in the central 3 mm optic zone were assessed using a photographic image-analysis system (EPCO2000). Follow-ups were performed postoperatively at 1 day, 6 months, 1 year and 2 years. Results: There were no significant differences in best corrected visual acuity, grade of ACO and capsulorrhexis/optic overlapping between IOL types during the follow-up period. Patients in the one-piece acrylic hydrophobic IOL group more frequently presented with capsular folds behind the IOL optic area than those in the three-piece IOL group. In the three-piece acrylic hydrophobic IOL group, PCO values (mean (SD)) of the entire IOL optic area were significantly lower six months postoperative (three-piece: 0.002 (0.009); one-piece: 0.007 (0.017); p=0.04), one year postoperative (three-piece: 0.004 (0.016); one-piece: 0.026 (0.041); p=0.001) as well as one year postoperative in the central 3 mm optic zone (three-piece: 0.000 (0.0002); one-piece: 0.019 (0.049); p=0.001). However, two years postoperative, the PCO values of the groups did not show significant differences (entire IOL optic area: three-piece, 0.136 (0.223); one-piece, 0.154 (0.190); p=0.18; central zone: three-piece, 0.023 (0.065); one-piece: 0.020 (0.039); p=0.44). Conclusion: The 2 year follow-up after cataract surgery showed no significant difference in ACO and PCO development between three-piece and one-piece acrylic hydrophobic intraocular lenses.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A11	`01`	`1`		`@1 ZEMAITIENE (Redo)`
A11	`02`	`1`		`@1 JASINSKAS (Vytautas)`
A11	`03`	`1`		`@1 AUFFARTH (Gerd U.)`
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C01	`01`		`ENG`	@0 Background: Posterior capsule opacification (PCO) is still a major long-term complication of modern cataract surgery. We evaluated the impact of sharp-edged intraocular lenses (lOLs) with different haptic designs made from the same hydrophobic acrylic material on posterior and anterior lens capsule opacification. Setting: Eye clinic of Kaunas University of Medicine, Lithuania. Prospective randomised clinical study. Methods: Seventy-four eyes of 74 patients scheduled for cataract surgery were included in a prospective randomised clinical study. Thirty-seven eyes of 37 patients received a three-piece acrylic hydrophobic (AcrySof, MA30BA, Alcon) IOL; and thirty-seven eyes of 37 patients received a one-piece acrylic hydrophobic (AcrySof, SA30AL, Alcon) IOL. Visual acuity, anterior capsule opacification (ACO), capsular folds, capsulorrhexis/optic overlapping and posterior capsule opacification (PCO) were evaluated. ACO was assessed subjectively. PCO values in the entire IOL optic area and in the central 3 mm optic zone were assessed using a photographic image-analysis system (EPCO2000). Follow-ups were performed postoperatively at 1 day, 6 months, 1 year and 2 years. Results: There were no significant differences in best corrected visual acuity, grade of ACO and capsulorrhexis/optic overlapping between IOL types during the follow-up period. Patients in the one-piece acrylic hydrophobic IOL group more frequently presented with capsular folds behind the IOL optic area than those in the three-piece IOL group. In the three-piece acrylic hydrophobic IOL group, PCO values (mean (SD)) of the entire IOL optic area were significantly lower six months postoperative (three-piece: 0.002 (0.009); one-piece: 0.007 (0.017); p=0.04), one year postoperative (three-piece: 0.004 (0.016); one-piece: 0.026 (0.041); p=0.001) as well as one year postoperative in the central 3 mm optic zone (three-piece: 0.000 (0.0002); one-piece: 0.019 (0.049); p=0.001). However, two years postoperative, the PCO values of the groups did not show significant differences (entire IOL optic area: three-piece, 0.136 (0.223); one-piece, 0.154 (0.190); p=0.18; central zone: three-piece, 0.023 (0.065); one-piece: 0.020 (0.039); p=0.44). Conclusion: The 2 year follow-up after cataract surgery showed no significant difference in ACO and PCO development between three-piece and one-piece acrylic hydrophobic intraocular lenses.
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Format Inist (serveur)

NO :	PASCAL 07-0207414 INIST
ET :	Influence of three-piece and single-piece designs of two sharp-edge optic hydrophobic acrylic intraocular lenses on the prevention of posterior capsule opacification : a prospective, randomised, long-term clinical trial
AU :	ZEMAITIENE (Redo); JASINSKAS (Vytautas); AUFFARTH (Gerd U.)
AF :	Eye Clinic of Kaunas University of Medicine/Kaunas/Lithuanie (1 aut., 2 aut.); Department of Ophthalmology, Ruprecht -Karls -University of Heidelberg/Heidelberg/Allemagne (3 aut.)
DT :	Publication en série; Compte-rendu; Niveau analytique
SO :	British journal of ophthalmology; ISSN 0007-1161; Coden BJOPAL; Royaume-Uni; Da. 2007; Vol. 91; No. 5; Pp. 644-648; Bibl. 33 ref.
LA :	Anglais
EA :	Background: Posterior capsule opacification (PCO) is still a major long-term complication of modern cataract surgery. We evaluated the impact of sharp-edged intraocular lenses (lOLs) with different haptic designs made from the same hydrophobic acrylic material on posterior and anterior lens capsule opacification. Setting: Eye clinic of Kaunas University of Medicine, Lithuania. Prospective randomised clinical study. Methods: Seventy-four eyes of 74 patients scheduled for cataract surgery were included in a prospective randomised clinical study. Thirty-seven eyes of 37 patients received a three-piece acrylic hydrophobic (AcrySof, MA30BA, Alcon) IOL; and thirty-seven eyes of 37 patients received a one-piece acrylic hydrophobic (AcrySof, SA30AL, Alcon) IOL. Visual acuity, anterior capsule opacification (ACO), capsular folds, capsulorrhexis/optic overlapping and posterior capsule opacification (PCO) were evaluated. ACO was assessed subjectively. PCO values in the entire IOL optic area and in the central 3 mm optic zone were assessed using a photographic image-analysis system (EPCO2000). Follow-ups were performed postoperatively at 1 day, 6 months, 1 year and 2 years. Results: There were no significant differences in best corrected visual acuity, grade of ACO and capsulorrhexis/optic overlapping between IOL types during the follow-up period. Patients in the one-piece acrylic hydrophobic IOL group more frequently presented with capsular folds behind the IOL optic area than those in the three-piece IOL group. In the three-piece acrylic hydrophobic IOL group, PCO values (mean (SD)) of the entire IOL optic area were significantly lower six months postoperative (three-piece: 0.002 (0.009); one-piece: 0.007 (0.017); p=0.04), one year postoperative (three-piece: 0.004 (0.016); one-piece: 0.026 (0.041); p=0.001) as well as one year postoperative in the central 3 mm optic zone (three-piece: 0.000 (0.0002); one-piece: 0.019 (0.049); p=0.001). However, two years postoperative, the PCO values of the groups did not show significant differences (entire IOL optic area: three-piece, 0.136 (0.223); one-piece, 0.154 (0.190); p=0.18; central zone: three-piece, 0.023 (0.065); one-piece: 0.020 (0.039); p=0.44). Conclusion: The 2 year follow-up after cataract surgery showed no significant difference in ACO and PCO development between three-piece and one-piece acrylic hydrophobic intraocular lenses.
CC :	002B09N
FD :	Influence; Conception; Bord; Optique; Lentille intraoculaire; Prévention; Postérieur; Capsule; Opacification; Prospective; Randomisation; Long terme; Essai clinique; Ophtalmologie; Traitement
FG :	Chirurgie
ED :	Influence; Design; Edge; Optics; Intraocular lens; Prevention; Posterior; Capsule; Opacification; Prospective; Randomization; Long term; Clinical trial; Ophthalmology; Treatment
EG :	Surgery
SD :	Influencia; Diseño; Borde; Optica; Lente intraocular; Prevención; Posterior; Cápsula; Opacificación; Prospectiva; Aleatorización; Largo plazo; Ensayo clínico; Oftalmología; Tratamiento
LO :	INIST-1015.354000143512420230
ID :	07-0207414

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Pascal:07-0207414

Le document en format XML

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<author><name sortKey="Jasinskas, Vytautas" sort="Jasinskas, Vytautas" uniqKey="Jasinskas V" first="Vytautas" last="Jasinskas">Vytautas Jasinskas</name>
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<author><name sortKey="Jasinskas, Vytautas" sort="Jasinskas, Vytautas" uniqKey="Jasinskas V" first="Vytautas" last="Jasinskas">Vytautas Jasinskas</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Capsule</term>
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<term>Intraocular lens</term>
<term>Long term</term>
<term>Opacification</term>
<term>Ophthalmology</term>
<term>Optics</term>
<term>Posterior</term>
<term>Prevention</term>
<term>Prospective</term>
<term>Randomization</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Influence</term>
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<term>Prévention</term>
<term>Postérieur</term>
<term>Capsule</term>
<term>Opacification</term>
<term>Prospective</term>
<term>Randomisation</term>
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<front><div type="abstract" xml:lang="en">Background: Posterior capsule opacification (PCO) is still a major long-term complication of modern cataract surgery. We evaluated the impact of sharp-edged intraocular lenses (lOLs) with different haptic designs made from the same hydrophobic acrylic material on posterior and anterior lens capsule opacification. Setting: Eye clinic of Kaunas University of Medicine, Lithuania. Prospective randomised clinical study. Methods: Seventy-four eyes of 74 patients scheduled for cataract surgery were included in a prospective randomised clinical study. Thirty-seven eyes of 37 patients received a three-piece acrylic hydrophobic (AcrySof, MA30BA, Alcon) IOL; and thirty-seven eyes of 37 patients received a one-piece acrylic hydrophobic (AcrySof, SA30AL, Alcon) IOL. Visual acuity, anterior capsule opacification (ACO), capsular folds, capsulorrhexis/optic overlapping and posterior capsule opacification (PCO) were evaluated. ACO was assessed subjectively. PCO values in the entire IOL optic area and in the central 3 mm optic zone were assessed using a photographic image-analysis system (EPCO2000). Follow-ups were performed postoperatively at 1 day, 6 months, 1 year and 2 years. Results: There were no significant differences in best corrected visual acuity, grade of ACO and capsulorrhexis/optic overlapping between IOL types during the follow-up period. Patients in the one-piece acrylic hydrophobic IOL group more frequently presented with capsular folds behind the IOL optic area than those in the three-piece IOL group. In the three-piece acrylic hydrophobic IOL group, PCO values (mean (SD)) of the entire IOL optic area were significantly lower six months postoperative (three-piece: 0.002 (0.009); one-piece: 0.007 (0.017); p=0.04), one year postoperative (three-piece: 0.004 (0.016); one-piece: 0.026 (0.041); p=0.001) as well as one year postoperative in the central 3 mm optic zone (three-piece: 0.000 (0.0002); one-piece: 0.019 (0.049); p=0.001). However, two years postoperative, the PCO values of the groups did not show significant differences (entire IOL optic area: three-piece, 0.136 (0.223); one-piece, 0.154 (0.190); p=0.18; central zone: three-piece, 0.023 (0.065); one-piece: 0.020 (0.039); p=0.44). Conclusion: The 2 year follow-up after cataract surgery showed no significant difference in ACO and PCO development between three-piece and one-piece acrylic hydrophobic intraocular lenses.</div>
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<fC01 i1="01" l="ENG"><s0>Background: Posterior capsule opacification (PCO) is still a major long-term complication of modern cataract surgery. We evaluated the impact of sharp-edged intraocular lenses (lOLs) with different haptic designs made from the same hydrophobic acrylic material on posterior and anterior lens capsule opacification. Setting: Eye clinic of Kaunas University of Medicine, Lithuania. Prospective randomised clinical study. Methods: Seventy-four eyes of 74 patients scheduled for cataract surgery were included in a prospective randomised clinical study. Thirty-seven eyes of 37 patients received a three-piece acrylic hydrophobic (AcrySof, MA30BA, Alcon) IOL; and thirty-seven eyes of 37 patients received a one-piece acrylic hydrophobic (AcrySof, SA30AL, Alcon) IOL. Visual acuity, anterior capsule opacification (ACO), capsular folds, capsulorrhexis/optic overlapping and posterior capsule opacification (PCO) were evaluated. ACO was assessed subjectively. PCO values in the entire IOL optic area and in the central 3 mm optic zone were assessed using a photographic image-analysis system (EPCO2000). Follow-ups were performed postoperatively at 1 day, 6 months, 1 year and 2 years. Results: There were no significant differences in best corrected visual acuity, grade of ACO and capsulorrhexis/optic overlapping between IOL types during the follow-up period. Patients in the one-piece acrylic hydrophobic IOL group more frequently presented with capsular folds behind the IOL optic area than those in the three-piece IOL group. In the three-piece acrylic hydrophobic IOL group, PCO values (mean (SD)) of the entire IOL optic area were significantly lower six months postoperative (three-piece: 0.002 (0.009); one-piece: 0.007 (0.017); p=0.04), one year postoperative (three-piece: 0.004 (0.016); one-piece: 0.026 (0.041); p=0.001) as well as one year postoperative in the central 3 mm optic zone (three-piece: 0.000 (0.0002); one-piece: 0.019 (0.049); p=0.001). However, two years postoperative, the PCO values of the groups did not show significant differences (entire IOL optic area: three-piece, 0.136 (0.223); one-piece, 0.154 (0.190); p=0.18; central zone: three-piece, 0.023 (0.065); one-piece: 0.020 (0.039); p=0.44). Conclusion: The 2 year follow-up after cataract surgery showed no significant difference in ACO and PCO development between three-piece and one-piece acrylic hydrophobic intraocular lenses.</s0>
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<fC02 i1="01" i2="X"><s0>002B09N</s0>
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<s5>02</s5>
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<s5>02</s5>
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<fC03 i1="01" i2="X" l="SPA"><s0>Influencia</s0>
<s5>02</s5>
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<fC03 i1="02" i2="X" l="FRE"><s0>Conception</s0>
<s5>03</s5>
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<fC03 i1="02" i2="X" l="ENG"><s0>Design</s0>
<s5>03</s5>
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<fC03 i1="02" i2="X" l="SPA"><s0>Diseño</s0>
<s5>03</s5>
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<fC03 i1="03" i2="X" l="FRE"><s0>Bord</s0>
<s5>05</s5>
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<fC03 i1="03" i2="X" l="ENG"><s0>Edge</s0>
<s5>05</s5>
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<fC03 i1="03" i2="X" l="SPA"><s0>Borde</s0>
<s5>05</s5>
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<fC03 i1="04" i2="X" l="FRE"><s0>Optique</s0>
<s5>06</s5>
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<s5>06</s5>
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<fC03 i1="04" i2="X" l="SPA"><s0>Optica</s0>
<s5>06</s5>
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<s5>08</s5>
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<fC03 i1="05" i2="X" l="ENG"><s0>Intraocular lens</s0>
<s5>08</s5>
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<fC03 i1="05" i2="X" l="SPA"><s0>Lente intraocular</s0>
<s5>08</s5>
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<fC03 i1="06" i2="X" l="FRE"><s0>Prévention</s0>
<s5>09</s5>
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<fC03 i1="06" i2="X" l="ENG"><s0>Prevention</s0>
<s5>09</s5>
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<fC03 i1="06" i2="X" l="SPA"><s0>Prevención</s0>
<s5>09</s5>
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<fC03 i1="07" i2="X" l="FRE"><s0>Postérieur</s0>
<s5>11</s5>
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<fC03 i1="07" i2="X" l="ENG"><s0>Posterior</s0>
<s5>11</s5>
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<fC03 i1="07" i2="X" l="SPA"><s0>Posterior</s0>
<s5>11</s5>
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<fC03 i1="08" i2="X" l="FRE"><s0>Capsule</s0>
<s5>12</s5>
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<fC03 i1="08" i2="X" l="ENG"><s0>Capsule</s0>
<s5>12</s5>
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<fC03 i1="08" i2="X" l="SPA"><s0>Cápsula</s0>
<s5>12</s5>
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<fC03 i1="09" i2="X" l="FRE"><s0>Opacification</s0>
<s5>14</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Opacification</s0>
<s5>14</s5>
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<fC03 i1="09" i2="X" l="SPA"><s0>Opacificación</s0>
<s5>14</s5>
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<fC03 i1="10" i2="X" l="FRE"><s0>Prospective</s0>
<s5>15</s5>
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<s5>15</s5>
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<fC03 i1="10" i2="X" l="SPA"><s0>Prospectiva</s0>
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<s5>17</s5>
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<fC03 i1="11" i2="X" l="SPA"><s0>Aleatorización</s0>
<s5>17</s5>
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<s5>18</s5>
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<fC03 i1="13" i2="X" l="FRE"><s0>Essai clinique</s0>
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<s5>20</s5>
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<s5>20</s5>
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<fC03 i1="14" i2="X" l="SPA"><s0>Oftalmología</s0>
<s5>20</s5>
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<fC03 i1="15" i2="X" l="FRE"><s0>Traitement</s0>
<s5>25</s5>
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<fC03 i1="15" i2="X" l="ENG"><s0>Treatment</s0>
<s5>25</s5>
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<fC03 i1="15" i2="X" l="SPA"><s0>Tratamiento</s0>
<s5>25</s5>
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<s5>37</s5>
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<s5>37</s5>
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<server><NO>PASCAL 07-0207414 INIST</NO>
<ET>Influence of three-piece and single-piece designs of two sharp-edge optic hydrophobic acrylic intraocular lenses on the prevention of posterior capsule opacification : a prospective, randomised, long-term clinical trial</ET>
<AU>ZEMAITIENE (Redo); JASINSKAS (Vytautas); AUFFARTH (Gerd U.)</AU>
<AF>Eye Clinic of Kaunas University of Medicine/Kaunas/Lithuanie (1 aut., 2 aut.); Department of Ophthalmology, Ruprecht -Karls -University of Heidelberg/Heidelberg/Allemagne (3 aut.)</AF>
<DT>Publication en série; Compte-rendu; Niveau analytique</DT>
<SO>British journal of ophthalmology; ISSN 0007-1161; Coden BJOPAL; Royaume-Uni; Da. 2007; Vol. 91; No. 5; Pp. 644-648; Bibl. 33 ref.</SO>
<LA>Anglais</LA>
<EA>Background: Posterior capsule opacification (PCO) is still a major long-term complication of modern cataract surgery. We evaluated the impact of sharp-edged intraocular lenses (lOLs) with different haptic designs made from the same hydrophobic acrylic material on posterior and anterior lens capsule opacification. Setting: Eye clinic of Kaunas University of Medicine, Lithuania. Prospective randomised clinical study. Methods: Seventy-four eyes of 74 patients scheduled for cataract surgery were included in a prospective randomised clinical study. Thirty-seven eyes of 37 patients received a three-piece acrylic hydrophobic (AcrySof, MA30BA, Alcon) IOL; and thirty-seven eyes of 37 patients received a one-piece acrylic hydrophobic (AcrySof, SA30AL, Alcon) IOL. Visual acuity, anterior capsule opacification (ACO), capsular folds, capsulorrhexis/optic overlapping and posterior capsule opacification (PCO) were evaluated. ACO was assessed subjectively. PCO values in the entire IOL optic area and in the central 3 mm optic zone were assessed using a photographic image-analysis system (EPCO2000). Follow-ups were performed postoperatively at 1 day, 6 months, 1 year and 2 years. Results: There were no significant differences in best corrected visual acuity, grade of ACO and capsulorrhexis/optic overlapping between IOL types during the follow-up period. Patients in the one-piece acrylic hydrophobic IOL group more frequently presented with capsular folds behind the IOL optic area than those in the three-piece IOL group. In the three-piece acrylic hydrophobic IOL group, PCO values (mean (SD)) of the entire IOL optic area were significantly lower six months postoperative (three-piece: 0.002 (0.009); one-piece: 0.007 (0.017); p=0.04), one year postoperative (three-piece: 0.004 (0.016); one-piece: 0.026 (0.041); p=0.001) as well as one year postoperative in the central 3 mm optic zone (three-piece: 0.000 (0.0002); one-piece: 0.019 (0.049); p=0.001). However, two years postoperative, the PCO values of the groups did not show significant differences (entire IOL optic area: three-piece, 0.136 (0.223); one-piece, 0.154 (0.190); p=0.18; central zone: three-piece, 0.023 (0.065); one-piece: 0.020 (0.039); p=0.44). Conclusion: The 2 year follow-up after cataract surgery showed no significant difference in ACO and PCO development between three-piece and one-piece acrylic hydrophobic intraocular lenses.</EA>
<CC>002B09N</CC>
<FD>Influence; Conception; Bord; Optique; Lentille intraoculaire; Prévention; Postérieur; Capsule; Opacification; Prospective; Randomisation; Long terme; Essai clinique; Ophtalmologie; Traitement</FD>
<FG>Chirurgie</FG>
<ED>Influence; Design; Edge; Optics; Intraocular lens; Prevention; Posterior; Capsule; Opacification; Prospective; Randomization; Long term; Clinical trial; Ophthalmology; Treatment</ED>
<EG>Surgery</EG>
<SD>Influencia; Diseño; Borde; Optica; Lente intraocular; Prevención; Posterior; Cápsula; Opacificación; Prospectiva; Aleatorización; Largo plazo; Ensayo clínico; Oftalmología; Tratamiento</SD>
<LO>INIST-1015.354000143512420230</LO>
<ID>07-0207414</ID>
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Influence of three-piece and single-piece designs of two sharp-edge optic hydrophobic acrylic intraocular lenses on the prevention of posterior capsule opacification : a prospective, randomised, long-term clinical trial

Influence of three-piece and single-piece designs of two sharp-edge optic hydrophobic acrylic intraocular lenses on the prevention of posterior capsule opacification : a prospective, randomised, long-term clinical trial

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