Word Intelligibility and Age Predict Visual Cortex Activity during Word Listening
Identifieur interne : 001B61 ( Ncbi/Curation ); précédent : 001B60; suivant : 001B62Word Intelligibility and Age Predict Visual Cortex Activity during Word Listening
Auteurs : Stefanie E. Kuchinsky ; Kenneth I. Vaden ; Noam I. Keren ; Kelly C. Harris ; Jayne B. Ahlstrom ; Judy R. Dubno ; Mark A. EckertSource :
- Cerebral Cortex (New York, NY) [ 1047-3211 ] ; 2012.
Abstract
The distractibility that older adults experience when listening to speech in challenging conditions has been attributed in part to reduced inhibition of irrelevant information within and across sensory systems. Whereas neuroimaging studies have shown that younger adults readily suppress visual cortex activation when listening to auditory stimuli, it is unclear the extent to which declining inhibition in older adults results in reduced suppression or compensatory engagement of other sensory cortices. The current functional magnetic resonance imaging study examined the effects of age and stimulus intelligibility in a word listening task. Across all participants, auditory cortex was engaged when listening to words. However, increasing age and declining word intelligibility had independent and spatially similar effects: both were associated with increasing engagement of visual cortex. Visual cortex activation was not explained by age-related differences in vascular reactivity but rather auditory and visual cortices were functionally connected across word listening conditions. The nature of this correlation changed with age: younger adults deactivated visual cortex when activating auditory cortex, middle-aged adults showed no relation, and older adults synchronously activated both cortices. These results suggest that age and stimulus integrity are additive modulators of crossmodal suppression and activation.
Url:
DOI: 10.1093/cercor/bhr211
PubMed: 21862447
PubMed Central: 3357178
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001335
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :001335
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :001471
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :001B61
Links to Exploration step
PMC:3357178Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Word Intelligibility and Age Predict Visual Cortex Activity during Word Listening</title>
<author><name sortKey="Kuchinsky, Stefanie E" sort="Kuchinsky, Stefanie E" uniqKey="Kuchinsky S" first="Stefanie E." last="Kuchinsky">Stefanie E. Kuchinsky</name>
</author>
<author><name sortKey="Vaden, Kenneth I" sort="Vaden, Kenneth I" uniqKey="Vaden K" first="Kenneth I." last="Vaden">Kenneth I. Vaden</name>
</author>
<author><name sortKey="Keren, Noam I" sort="Keren, Noam I" uniqKey="Keren N" first="Noam I." last="Keren">Noam I. Keren</name>
</author>
<author><name sortKey="Harris, Kelly C" sort="Harris, Kelly C" uniqKey="Harris K" first="Kelly C." last="Harris">Kelly C. Harris</name>
</author>
<author><name sortKey="Ahlstrom, Jayne B" sort="Ahlstrom, Jayne B" uniqKey="Ahlstrom J" first="Jayne B." last="Ahlstrom">Jayne B. Ahlstrom</name>
</author>
<author><name sortKey="Dubno, Judy R" sort="Dubno, Judy R" uniqKey="Dubno J" first="Judy R." last="Dubno">Judy R. Dubno</name>
</author>
<author><name sortKey="Eckert, Mark A" sort="Eckert, Mark A" uniqKey="Eckert M" first="Mark A." last="Eckert">Mark A. Eckert</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">21862447</idno>
<idno type="pmc">3357178</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357178</idno>
<idno type="RBID">PMC:3357178</idno>
<idno type="doi">10.1093/cercor/bhr211</idno>
<date when="2012">2012</date>
<idno type="wicri:Area/Pmc/Corpus">001335</idno>
<idno type="wicri:Area/Pmc/Curation">001335</idno>
<idno type="wicri:Area/Pmc/Checkpoint">001471</idno>
<idno type="wicri:Area/Ncbi/Merge">001B61</idno>
<idno type="wicri:Area/Ncbi/Curation">001B61</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Word Intelligibility and Age Predict Visual Cortex Activity during Word Listening</title>
<author><name sortKey="Kuchinsky, Stefanie E" sort="Kuchinsky, Stefanie E" uniqKey="Kuchinsky S" first="Stefanie E." last="Kuchinsky">Stefanie E. Kuchinsky</name>
</author>
<author><name sortKey="Vaden, Kenneth I" sort="Vaden, Kenneth I" uniqKey="Vaden K" first="Kenneth I." last="Vaden">Kenneth I. Vaden</name>
</author>
<author><name sortKey="Keren, Noam I" sort="Keren, Noam I" uniqKey="Keren N" first="Noam I." last="Keren">Noam I. Keren</name>
</author>
<author><name sortKey="Harris, Kelly C" sort="Harris, Kelly C" uniqKey="Harris K" first="Kelly C." last="Harris">Kelly C. Harris</name>
</author>
<author><name sortKey="Ahlstrom, Jayne B" sort="Ahlstrom, Jayne B" uniqKey="Ahlstrom J" first="Jayne B." last="Ahlstrom">Jayne B. Ahlstrom</name>
</author>
<author><name sortKey="Dubno, Judy R" sort="Dubno, Judy R" uniqKey="Dubno J" first="Judy R." last="Dubno">Judy R. Dubno</name>
</author>
<author><name sortKey="Eckert, Mark A" sort="Eckert, Mark A" uniqKey="Eckert M" first="Mark A." last="Eckert">Mark A. Eckert</name>
</author>
</analytic>
<series><title level="j">Cerebral Cortex (New York, NY)</title>
<idno type="ISSN">1047-3211</idno>
<idno type="eISSN">1460-2199</idno>
<imprint><date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>The distractibility that older adults experience when listening to speech in challenging conditions has been attributed in part to reduced inhibition of irrelevant information within and across sensory systems. Whereas neuroimaging studies have shown that younger adults readily suppress visual cortex activation when listening to auditory stimuli, it is unclear the extent to which declining inhibition in older adults results in reduced suppression or compensatory engagement of other sensory cortices. The current functional magnetic resonance imaging study examined the effects of age and stimulus intelligibility in a word listening task. Across all participants, auditory cortex was engaged when listening to words. However, increasing age and declining word intelligibility had independent and spatially similar effects: both were associated with increasing engagement of visual cortex. Visual cortex activation was not explained by age-related differences in vascular reactivity but rather auditory and visual cortices were functionally connected across word listening conditions. The nature of this correlation changed with age: younger adults deactivated visual cortex when activating auditory cortex, middle-aged adults showed no relation, and older adults synchronously activated both cortices. These results suggest that age and stimulus integrity are additive modulators of crossmodal suppression and activation.</p>
</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001B61 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 001B61 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Ticri/CIDE |area= HapticV1 |flux= Ncbi |étape= Curation |type= RBID |clé= PMC:3357178 |texte= Word Intelligibility and Age Predict Visual Cortex Activity during Word Listening }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:21862447" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a HapticV1
![]() | This area was generated with Dilib version V0.6.23. | ![]() |