Long-term effect of 1-piece and 3-piece hydrophobic acrylic intraocular lens on posterior capsule opacification : A Randomized Trial
Identifieur interne : 005988 ( Main/Curation ); précédent : 005987; suivant : 005989Long-term effect of 1-piece and 3-piece hydrophobic acrylic intraocular lens on posterior capsule opacification : A Randomized Trial
Auteurs : Christina Leydolt [Autriche] ; Sofija Davidovic [Autriche, Serbie] ; Stefan Sacu [Autriche] ; Rupert Menapace [Autriche] ; Thomas Neumayer [Autriche] ; Ana Prinz [Autriche] ; Wolf Buehl [Autriche] ; Oliver Findl [Autriche]Source :
- Ophthalmology : (Rochester, MN) [ 0161-6420 ] ; 2007.
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- Pascal (Inist)
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Abstract
Purpose: To compare the intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of the foldable hydrophobic acrylic AcrySof intraocular lens (IOL) over a 5-year period. Design: Randomized, prospective, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each study patient had cataract surgery in both eyes and received a 1 -piece AcrySof IOL in 1 eye and a 3-piece AcrySof IOL in the other eye. Follow-up examinations were performed at 1 week, 1 month, 6 months, and 1, 2, and 5 years. Digital retroillumination images were obtained of each eye. The amount of posterior capsule opacification (score range, 0-10) was assessed subjectively at the slit lamp and objectively using automated image analysis software 1, 2, and 5 years after surgery. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between the 1 -piece and 3-piece AcrySof IOL in best-corrected visual acuity, overlap of rhexis and IOL, capsular folds, anterior capsule opacification, and posterior capsule opacification (1-piece AcrySof PCO score, 1.7±1.7; 3-piece AcrySof PCO score, 1.3±1.4; P = 0.30). Conclusions: Modification of the IOL haptic design of the sharp optic edged AcrySof IOL from a 3-piece to a 1-piece haptic design caused no significant change in PCO intensity and neodymium:yttrium-aluminium-garnet laser treatment rate 5 years after surgery.
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acrylic polymer</term>
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<term>Long term</term>
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<term>Ophthalmology</term>
<term>Posterior</term>
<term>Randomization</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Long terme</term>
<term>Acrylique dérivé polymère</term>
<term>Postérieur</term>
<term>Capsule</term>
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<front><div type="abstract" xml:lang="en">Purpose: To compare the intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of the foldable hydrophobic acrylic AcrySof intraocular lens (IOL) over a 5-year period. Design: Randomized, prospective, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each study patient had cataract surgery in both eyes and received a 1 -piece AcrySof IOL in 1 eye and a 3-piece AcrySof IOL in the other eye. Follow-up examinations were performed at 1 week, 1 month, 6 months, and 1, 2, and 5 years. Digital retroillumination images were obtained of each eye. The amount of posterior capsule opacification (score range, 0-10) was assessed subjectively at the slit lamp and objectively using automated image analysis software 1, 2, and 5 years after surgery. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between the 1 -piece and 3-piece AcrySof IOL in best-corrected visual acuity, overlap of rhexis and IOL, capsular folds, anterior capsule opacification, and posterior capsule opacification (1-piece AcrySof PCO score, 1.7±1.7; 3-piece AcrySof PCO score, 1.3±1.4; P = 0.30). Conclusions: Modification of the IOL haptic design of the sharp optic edged AcrySof IOL from a 3-piece to a 1-piece haptic design caused no significant change in PCO intensity and neodymium:yttrium-aluminium-garnet laser treatment rate 5 years after surgery.</div>
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