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Long-term effect of 1-piece and 3-piece hydrophobic acrylic intraocular lens on posterior capsule opacification : A Randomized Trial

Identifieur interne : 000B18 ( PascalFrancis/Corpus ); précédent : 000B17; suivant : 000B19

Long-term effect of 1-piece and 3-piece hydrophobic acrylic intraocular lens on posterior capsule opacification : A Randomized Trial

Auteurs : Christina Leydolt ; Sofija Davidovic ; Stefan Sacu ; Rupert Menapace ; Thomas Neumayer ; Ana Prinz ; Wolf Buehl ; Oliver Findl

Source :

RBID : Pascal:07-0410735

Descripteurs français

English descriptors

Abstract

Purpose: To compare the intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of the foldable hydrophobic acrylic AcrySof intraocular lens (IOL) over a 5-year period. Design: Randomized, prospective, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each study patient had cataract surgery in both eyes and received a 1 -piece AcrySof IOL in 1 eye and a 3-piece AcrySof IOL in the other eye. Follow-up examinations were performed at 1 week, 1 month, 6 months, and 1, 2, and 5 years. Digital retroillumination images were obtained of each eye. The amount of posterior capsule opacification (score range, 0-10) was assessed subjectively at the slit lamp and objectively using automated image analysis software 1, 2, and 5 years after surgery. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between the 1 -piece and 3-piece AcrySof IOL in best-corrected visual acuity, overlap of rhexis and IOL, capsular folds, anterior capsule opacification, and posterior capsule opacification (1-piece AcrySof PCO score, 1.7±1.7; 3-piece AcrySof PCO score, 1.3±1.4; P = 0.30). Conclusions: Modification of the IOL haptic design of the sharp optic edged AcrySof IOL from a 3-piece to a 1-piece haptic design caused no significant change in PCO intensity and neodymium:yttrium-aluminium-garnet laser treatment rate 5 years after surgery.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0161-6420
A02 01      @0 OPHTDG
A03   1    @0 Ophthalmology : (Rochester MN)
A05       @2 114
A06       @2 9
A08 01  1  ENG  @1 Long-term effect of 1-piece and 3-piece hydrophobic acrylic intraocular lens on posterior capsule opacification : A Randomized Trial
A11 01  1    @1 LEYDOLT (Christina)
A11 02  1    @1 DAVIDOVIC (Sofija)
A11 03  1    @1 SACU (Stefan)
A11 04  1    @1 MENAPACE (Rupert)
A11 05  1    @1 NEUMAYER (Thomas)
A11 06  1    @1 PRINZ (Ana)
A11 07  1    @1 BUEHL (Wolf)
A11 08  1    @1 FINDL (Oliver)
A14 01      @1 Department of Ophthalmology, Medical University of Vienna @2 Vienna @3 AUT @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut. @Z 7 aut. @Z 8 aut.
A14 02      @1 Novi Sad Clinical Centre Eye Clinic @2 Novi Sad @3 SCG @Z 2 aut.
A20       @1 1663-1669
A21       @1 2007
A23 01      @0 ENG
A43 01      @1 INIST @2 18914 @5 354000161579690100
A44       @0 0000 @1 © 2007 INIST-CNRS. All rights reserved.
A45       @0 31 ref.
A47 01  1    @0 07-0410735
A60       @1 P
A61       @0 A
A64 01  1    @0 Ophthalmology : (Rochester, MN)
A66 01      @0 USA
C01 01    ENG  @0 Purpose: To compare the intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of the foldable hydrophobic acrylic AcrySof intraocular lens (IOL) over a 5-year period. Design: Randomized, prospective, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each study patient had cataract surgery in both eyes and received a 1 -piece AcrySof IOL in 1 eye and a 3-piece AcrySof IOL in the other eye. Follow-up examinations were performed at 1 week, 1 month, 6 months, and 1, 2, and 5 years. Digital retroillumination images were obtained of each eye. The amount of posterior capsule opacification (score range, 0-10) was assessed subjectively at the slit lamp and objectively using automated image analysis software 1, 2, and 5 years after surgery. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between the 1 -piece and 3-piece AcrySof IOL in best-corrected visual acuity, overlap of rhexis and IOL, capsular folds, anterior capsule opacification, and posterior capsule opacification (1-piece AcrySof PCO score, 1.7±1.7; 3-piece AcrySof PCO score, 1.3±1.4; P = 0.30). Conclusions: Modification of the IOL haptic design of the sharp optic edged AcrySof IOL from a 3-piece to a 1-piece haptic design caused no significant change in PCO intensity and neodymium:yttrium-aluminium-garnet laser treatment rate 5 years after surgery.
C02 01  X    @0 002B09N
C03 01  X  FRE  @0 Long terme @5 02
C03 01  X  ENG  @0 Long term @5 02
C03 01  X  SPA  @0 Largo plazo @5 02
C03 02  X  FRE  @0 Acrylique dérivé polymère @2 NK @5 03
C03 02  X  ENG  @0 Acrylic polymer @2 NK @5 03
C03 02  X  SPA  @0 Acrilico derivado polímero @2 NK @5 03
C03 03  X  FRE  @0 Postérieur @5 05
C03 03  X  ENG  @0 Posterior @5 05
C03 03  X  SPA  @0 Posterior @5 05
C03 04  X  FRE  @0 Capsule @5 06
C03 04  X  ENG  @0 Capsule @5 06
C03 04  X  SPA  @0 Cápsula @5 06
C03 05  X  FRE  @0 Opacification @5 08
C03 05  X  ENG  @0 Opacification @5 08
C03 05  X  SPA  @0 Opacificación @5 08
C03 06  X  FRE  @0 Randomisation @5 09
C03 06  X  ENG  @0 Randomization @5 09
C03 06  X  SPA  @0 Aleatorización @5 09
C03 07  X  FRE  @0 Ophtalmologie @5 11
C03 07  X  ENG  @0 Ophthalmology @5 11
C03 07  X  SPA  @0 Oftalmología @5 11
N21       @1 267
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 07-0410735 INIST
ET : Long-term effect of 1-piece and 3-piece hydrophobic acrylic intraocular lens on posterior capsule opacification : A Randomized Trial
AU : LEYDOLT (Christina); DAVIDOVIC (Sofija); SACU (Stefan); MENAPACE (Rupert); NEUMAYER (Thomas); PRINZ (Ana); BUEHL (Wolf); FINDL (Oliver)
AF : Department of Ophthalmology, Medical University of Vienna/Vienna/Autriche (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut., 7 aut., 8 aut.); Novi Sad Clinical Centre Eye Clinic/Novi Sad/Serbie-et-Monténégro (2 aut.)
DT : Publication en série; Niveau analytique
SO : Ophthalmology : (Rochester, MN); ISSN 0161-6420; Coden OPHTDG; Etats-Unis; Da. 2007; Vol. 114; No. 9; Pp. 1663-1669; Bibl. 31 ref.
LA : Anglais
EA : Purpose: To compare the intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of the foldable hydrophobic acrylic AcrySof intraocular lens (IOL) over a 5-year period. Design: Randomized, prospective, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each study patient had cataract surgery in both eyes and received a 1 -piece AcrySof IOL in 1 eye and a 3-piece AcrySof IOL in the other eye. Follow-up examinations were performed at 1 week, 1 month, 6 months, and 1, 2, and 5 years. Digital retroillumination images were obtained of each eye. The amount of posterior capsule opacification (score range, 0-10) was assessed subjectively at the slit lamp and objectively using automated image analysis software 1, 2, and 5 years after surgery. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between the 1 -piece and 3-piece AcrySof IOL in best-corrected visual acuity, overlap of rhexis and IOL, capsular folds, anterior capsule opacification, and posterior capsule opacification (1-piece AcrySof PCO score, 1.7±1.7; 3-piece AcrySof PCO score, 1.3±1.4; P = 0.30). Conclusions: Modification of the IOL haptic design of the sharp optic edged AcrySof IOL from a 3-piece to a 1-piece haptic design caused no significant change in PCO intensity and neodymium:yttrium-aluminium-garnet laser treatment rate 5 years after surgery.
CC : 002B09N
FD : Long terme; Acrylique dérivé polymère; Postérieur; Capsule; Opacification; Randomisation; Ophtalmologie
ED : Long term; Acrylic polymer; Posterior; Capsule; Opacification; Randomization; Ophthalmology
SD : Largo plazo; Acrilico derivado polímero; Posterior; Cápsula; Opacificación; Aleatorización; Oftalmología
LO : INIST-18914.354000161579690100
ID : 07-0410735

Links to Exploration step

Pascal:07-0410735

Le document en format XML

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<div type="abstract" xml:lang="en">Purpose: To compare the intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of the foldable hydrophobic acrylic AcrySof intraocular lens (IOL) over a 5-year period. Design: Randomized, prospective, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each study patient had cataract surgery in both eyes and received a 1 -piece AcrySof IOL in 1 eye and a 3-piece AcrySof IOL in the other eye. Follow-up examinations were performed at 1 week, 1 month, 6 months, and 1, 2, and 5 years. Digital retroillumination images were obtained of each eye. The amount of posterior capsule opacification (score range, 0-10) was assessed subjectively at the slit lamp and objectively using automated image analysis software 1, 2, and 5 years after surgery. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between the 1 -piece and 3-piece AcrySof IOL in best-corrected visual acuity, overlap of rhexis and IOL, capsular folds, anterior capsule opacification, and posterior capsule opacification (1-piece AcrySof PCO score, 1.7±1.7; 3-piece AcrySof PCO score, 1.3±1.4; P = 0.30). Conclusions: Modification of the IOL haptic design of the sharp optic edged AcrySof IOL from a 3-piece to a 1-piece haptic design caused no significant change in PCO intensity and neodymium:yttrium-aluminium-garnet laser treatment rate 5 years after surgery.</div>
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<s2>114</s2>
</fA05>
<fA06>
<s2>9</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG">
<s1>Long-term effect of 1-piece and 3-piece hydrophobic acrylic intraocular lens on posterior capsule opacification : A Randomized Trial</s1>
</fA08>
<fA11 i1="01" i2="1">
<s1>LEYDOLT (Christina)</s1>
</fA11>
<fA11 i1="02" i2="1">
<s1>DAVIDOVIC (Sofija)</s1>
</fA11>
<fA11 i1="03" i2="1">
<s1>SACU (Stefan)</s1>
</fA11>
<fA11 i1="04" i2="1">
<s1>MENAPACE (Rupert)</s1>
</fA11>
<fA11 i1="05" i2="1">
<s1>NEUMAYER (Thomas)</s1>
</fA11>
<fA11 i1="06" i2="1">
<s1>PRINZ (Ana)</s1>
</fA11>
<fA11 i1="07" i2="1">
<s1>BUEHL (Wolf)</s1>
</fA11>
<fA11 i1="08" i2="1">
<s1>FINDL (Oliver)</s1>
</fA11>
<fA14 i1="01">
<s1>Department of Ophthalmology, Medical University of Vienna</s1>
<s2>Vienna</s2>
<s3>AUT</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</fA14>
<fA14 i1="02">
<s1>Novi Sad Clinical Centre Eye Clinic</s1>
<s2>Novi Sad</s2>
<s3>SCG</s3>
<sZ>2 aut.</sZ>
</fA14>
<fA20>
<s1>1663-1669</s1>
</fA20>
<fA21>
<s1>2007</s1>
</fA21>
<fA23 i1="01">
<s0>ENG</s0>
</fA23>
<fA43 i1="01">
<s1>INIST</s1>
<s2>18914</s2>
<s5>354000161579690100</s5>
</fA43>
<fA44>
<s0>0000</s0>
<s1>© 2007 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45>
<s0>31 ref.</s0>
</fA45>
<fA47 i1="01" i2="1">
<s0>07-0410735</s0>
</fA47>
<fA60>
<s1>P</s1>
</fA60>
<fA61>
<s0>A</s0>
</fA61>
<fA64 i1="01" i2="1">
<s0>Ophthalmology : (Rochester, MN)</s0>
</fA64>
<fA66 i1="01">
<s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG">
<s0>Purpose: To compare the intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of the foldable hydrophobic acrylic AcrySof intraocular lens (IOL) over a 5-year period. Design: Randomized, prospective, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each study patient had cataract surgery in both eyes and received a 1 -piece AcrySof IOL in 1 eye and a 3-piece AcrySof IOL in the other eye. Follow-up examinations were performed at 1 week, 1 month, 6 months, and 1, 2, and 5 years. Digital retroillumination images were obtained of each eye. The amount of posterior capsule opacification (score range, 0-10) was assessed subjectively at the slit lamp and objectively using automated image analysis software 1, 2, and 5 years after surgery. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between the 1 -piece and 3-piece AcrySof IOL in best-corrected visual acuity, overlap of rhexis and IOL, capsular folds, anterior capsule opacification, and posterior capsule opacification (1-piece AcrySof PCO score, 1.7±1.7; 3-piece AcrySof PCO score, 1.3±1.4; P = 0.30). Conclusions: Modification of the IOL haptic design of the sharp optic edged AcrySof IOL from a 3-piece to a 1-piece haptic design caused no significant change in PCO intensity and neodymium:yttrium-aluminium-garnet laser treatment rate 5 years after surgery.</s0>
</fC01>
<fC02 i1="01" i2="X">
<s0>002B09N</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE">
<s0>Long terme</s0>
<s5>02</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG">
<s0>Long term</s0>
<s5>02</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA">
<s0>Largo plazo</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE">
<s0>Acrylique dérivé polymère</s0>
<s2>NK</s2>
<s5>03</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG">
<s0>Acrylic polymer</s0>
<s2>NK</s2>
<s5>03</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Acrilico derivado polímero</s0>
<s2>NK</s2>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Postérieur</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Posterior</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Posterior</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Capsule</s0>
<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Capsule</s0>
<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Cápsula</s0>
<s5>06</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Opacification</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Opacification</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Opacificación</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Randomisation</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Randomization</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Aleatorización</s0>
<s5>09</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Ophtalmologie</s0>
<s5>11</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Ophthalmology</s0>
<s5>11</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Oftalmología</s0>
<s5>11</s5>
</fC03>
<fN21>
<s1>267</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
<server>
<NO>PASCAL 07-0410735 INIST</NO>
<ET>Long-term effect of 1-piece and 3-piece hydrophobic acrylic intraocular lens on posterior capsule opacification : A Randomized Trial</ET>
<AU>LEYDOLT (Christina); DAVIDOVIC (Sofija); SACU (Stefan); MENAPACE (Rupert); NEUMAYER (Thomas); PRINZ (Ana); BUEHL (Wolf); FINDL (Oliver)</AU>
<AF>Department of Ophthalmology, Medical University of Vienna/Vienna/Autriche (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut., 7 aut., 8 aut.); Novi Sad Clinical Centre Eye Clinic/Novi Sad/Serbie-et-Monténégro (2 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Ophthalmology : (Rochester, MN); ISSN 0161-6420; Coden OPHTDG; Etats-Unis; Da. 2007; Vol. 114; No. 9; Pp. 1663-1669; Bibl. 31 ref.</SO>
<LA>Anglais</LA>
<EA>Purpose: To compare the intensity of posterior capsule opacification (PCO) between the 1-piece and 3-piece haptic designs of the foldable hydrophobic acrylic AcrySof intraocular lens (IOL) over a 5-year period. Design: Randomized, prospective, patient- and examiner-masked clinical trial with intraindividual comparison. Participants: Fifty-two patients with bilateral age-related cataract (104 eyes). Methods: Each study patient had cataract surgery in both eyes and received a 1 -piece AcrySof IOL in 1 eye and a 3-piece AcrySof IOL in the other eye. Follow-up examinations were performed at 1 week, 1 month, 6 months, and 1, 2, and 5 years. Digital retroillumination images were obtained of each eye. The amount of posterior capsule opacification (score range, 0-10) was assessed subjectively at the slit lamp and objectively using automated image analysis software 1, 2, and 5 years after surgery. Main Outcome Measure: Posterior capsule opacification score (scale, 0-10). Results: There was no significant difference between the 1 -piece and 3-piece AcrySof IOL in best-corrected visual acuity, overlap of rhexis and IOL, capsular folds, anterior capsule opacification, and posterior capsule opacification (1-piece AcrySof PCO score, 1.7±1.7; 3-piece AcrySof PCO score, 1.3±1.4; P = 0.30). Conclusions: Modification of the IOL haptic design of the sharp optic edged AcrySof IOL from a 3-piece to a 1-piece haptic design caused no significant change in PCO intensity and neodymium:yttrium-aluminium-garnet laser treatment rate 5 years after surgery.</EA>
<CC>002B09N</CC>
<FD>Long terme; Acrylique dérivé polymère; Postérieur; Capsule; Opacification; Randomisation; Ophtalmologie</FD>
<ED>Long term; Acrylic polymer; Posterior; Capsule; Opacification; Randomization; Ophthalmology</ED>
<SD>Largo plazo; Acrilico derivado polímero; Posterior; Cápsula; Opacificación; Aleatorización; Oftalmología</SD>
<LO>INIST-18914.354000161579690100</LO>
<ID>07-0410735</ID>
</server>
</inist>
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