Haptic Guided Virtual Reality Simulation for Targeted Drug Delivery Using Nano-Containers Manipulation
Identifieur interne : 001F37 ( Main/Curation ); précédent : 001F36; suivant : 001F38Haptic Guided Virtual Reality Simulation for Targeted Drug Delivery Using Nano-Containers Manipulation
Auteurs : SYED HASSAN [Corée du Sud] ; MOHSIN SHAH [Corée du Sud] ; SUNG CHUL YOON [Corée du Sud] ; IKRAM ULLAH [Corée du Sud] ; MYEONG OK KIM [Corée du Sud] ; JUNGWON YOON [Corée du Sud]Source :
- Journal of biomedical nanotechnology : (Print) [ 1550-7033 ] ; 2013.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Toxicomanie, Réalité virtuelle, Simulation, Nanotechnologie.
English descriptors
- KwdEn :
Abstract
When dealing with nano targeted drug delivery process the significant area of virtual reality application can be visualizing real time process and simulating it at nano-scale, since the effectiveness of a drug primarily depends on the affected cell and targeted doze. This paper proposes virtual reality (VR) as a tool to analyze and simulate nanoparticles (NPs) manipulation, in this paper amorphous NPs are analyzed and simulated in virtual environment. Haptic guides virtualizing the atomic force microscope (AFM) is applied in the virtual environment which allows the operators to sense and touch the NPs when evaluating its structure, drug release time, and behavioral study. Cisplatin was loaded as a modal drug to the self-assembled amorphous copolymer P(3HV-co-4HB)-b-mPEG NPs, where the efficiency and bioavailability of Cisplatin was further investigated. The prepared NPs when simulated in virtual environment proved to show good biocompatibility. Results showed that amorphous polymeric NPs could be efficient vehicles for the constant and targeted delivery of toxic anticancer drugs.
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000189
- to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000258
- to stream PascalFrancis, to step Curation: Pour aller vers cette notice dans l'étape Curation :001110
- to stream PascalFrancis, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000148
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :001F59
Links to Exploration step
Pascal:13-0241843Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Haptic Guided Virtual Reality Simulation for Targeted Drug Delivery Using Nano-Containers Manipulation</title>
<author><name sortKey="Syed Hassan" sort="Syed Hassan" uniqKey="Syed Hassan" last="Syed Hassan">SYED HASSAN</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>School of Mechanical and Aerospace Engineering and ReCAPT, Gyeongsang National University</s1>
<s2>Jinju, 660-701</s2>
<s3>KOR</s3>
<sZ>1 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<wicri:noRegion>Jinju, 660-701</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mohsin Shah" sort="Mohsin Shah" uniqKey="Mohsin Shah" last="Mohsin Shah">MOHSIN SHAH</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Nano-Biomaterials Science Laboratory, NRF Funded Pioneer Research Center for Alzheimer Disease Control and Division of Applied Life Sciences (BK21), Graduate School, Gyeongsang National University</s1>
<s2>Jinju 660-701</s2>
<s3>KOR</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<wicri:noRegion>Jinju 660-701</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sung Chul Yoon" sort="Sung Chul Yoon" uniqKey="Sung Chul Yoon" last="Sung Chul Yoon">SUNG CHUL YOON</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Nano-Biomaterials Science Laboratory, NRF Funded Pioneer Research Center for Alzheimer Disease Control and Division of Applied Life Sciences (BK21), Graduate School, Gyeongsang National University</s1>
<s2>Jinju 660-701</s2>
<s3>KOR</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<wicri:noRegion>Jinju 660-701</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ikram Ullah" sort="Ikram Ullah" uniqKey="Ikram Ullah" last="Ikram Ullah">IKRAM ULLAH</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Division of Applied Life Sciences Gyeongsang National University</s1>
<s2>660-701, Jinju</s2>
<s3>KOR</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<wicri:noRegion>Division of Applied Life Sciences Gyeongsang National University</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Myeong Ok Kim" sort="Myeong Ok Kim" uniqKey="Myeong Ok Kim" last="Myeong Ok Kim">MYEONG OK KIM</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Division of Applied Life Sciences Gyeongsang National University</s1>
<s2>660-701, Jinju</s2>
<s3>KOR</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<wicri:noRegion>Division of Applied Life Sciences Gyeongsang National University</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jungwon Yoon" sort="Jungwon Yoon" uniqKey="Jungwon Yoon" last="Jungwon Yoon">JUNGWON YOON</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>School of Mechanical and Aerospace Engineering and ReCAPT, Gyeongsang National University</s1>
<s2>Jinju, 660-701</s2>
<s3>KOR</s3>
<sZ>1 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<wicri:noRegion>Jinju, 660-701</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">13-0241843</idno>
<date when="2013">2013</date>
<idno type="stanalyst">PASCAL 13-0241843 INIST</idno>
<idno type="RBID">Pascal:13-0241843</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000189</idno>
<idno type="stanalyst">FRANCIS 13-0241843 INIST</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000258</idno>
<idno type="wicri:Area/PascalFrancis/Curation">001110</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000148</idno>
<idno type="wicri:doubleKey">1550-7033:2013:Syed Hassan:haptic:guided:virtual</idno>
<idno type="wicri:Area/Main/Merge">001F59</idno>
<idno type="wicri:Area/Main/Curation">001F37</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Haptic Guided Virtual Reality Simulation for Targeted Drug Delivery Using Nano-Containers Manipulation</title>
<author><name sortKey="Syed Hassan" sort="Syed Hassan" uniqKey="Syed Hassan" last="Syed Hassan">SYED HASSAN</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>School of Mechanical and Aerospace Engineering and ReCAPT, Gyeongsang National University</s1>
<s2>Jinju, 660-701</s2>
<s3>KOR</s3>
<sZ>1 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<wicri:noRegion>Jinju, 660-701</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mohsin Shah" sort="Mohsin Shah" uniqKey="Mohsin Shah" last="Mohsin Shah">MOHSIN SHAH</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Nano-Biomaterials Science Laboratory, NRF Funded Pioneer Research Center for Alzheimer Disease Control and Division of Applied Life Sciences (BK21), Graduate School, Gyeongsang National University</s1>
<s2>Jinju 660-701</s2>
<s3>KOR</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<wicri:noRegion>Jinju 660-701</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sung Chul Yoon" sort="Sung Chul Yoon" uniqKey="Sung Chul Yoon" last="Sung Chul Yoon">SUNG CHUL YOON</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Nano-Biomaterials Science Laboratory, NRF Funded Pioneer Research Center for Alzheimer Disease Control and Division of Applied Life Sciences (BK21), Graduate School, Gyeongsang National University</s1>
<s2>Jinju 660-701</s2>
<s3>KOR</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<wicri:noRegion>Jinju 660-701</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ikram Ullah" sort="Ikram Ullah" uniqKey="Ikram Ullah" last="Ikram Ullah">IKRAM ULLAH</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Division of Applied Life Sciences Gyeongsang National University</s1>
<s2>660-701, Jinju</s2>
<s3>KOR</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<wicri:noRegion>Division of Applied Life Sciences Gyeongsang National University</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Myeong Ok Kim" sort="Myeong Ok Kim" uniqKey="Myeong Ok Kim" last="Myeong Ok Kim">MYEONG OK KIM</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Division of Applied Life Sciences Gyeongsang National University</s1>
<s2>660-701, Jinju</s2>
<s3>KOR</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<wicri:noRegion>Division of Applied Life Sciences Gyeongsang National University</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jungwon Yoon" sort="Jungwon Yoon" uniqKey="Jungwon Yoon" last="Jungwon Yoon">JUNGWON YOON</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>School of Mechanical and Aerospace Engineering and ReCAPT, Gyeongsang National University</s1>
<s2>Jinju, 660-701</s2>
<s3>KOR</s3>
<sZ>1 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<wicri:noRegion>Jinju, 660-701</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Journal of biomedical nanotechnology : (Print)</title>
<title level="j" type="abbreviated">J. biomed. nanotechnol. : (Print)</title>
<idno type="ISSN">1550-7033</idno>
<imprint><date when="2013">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Journal of biomedical nanotechnology : (Print)</title>
<title level="j" type="abbreviated">J. biomed. nanotechnol. : (Print)</title>
<idno type="ISSN">1550-7033</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Augmented reality</term>
<term>Control release polymer</term>
<term>Drug addiction</term>
<term>Drug carrier</term>
<term>Guidance</term>
<term>Manipulation</term>
<term>Nanoparticle</term>
<term>Nanotechnology</term>
<term>Simulation</term>
<term>Targeted drug</term>
<term>Targeted therapy</term>
<term>Treatment</term>
<term>Virtual reality</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Toxicomanie</term>
<term>Thérapeutique ciblée</term>
<term>Guidage</term>
<term>Réalité virtuelle</term>
<term>Réalité augmentée</term>
<term>Simulation</term>
<term>Médicament ciblé</term>
<term>Vecteur médicament</term>
<term>Traitement</term>
<term>Manipulation</term>
<term>Nanoparticule</term>
<term>Nanotechnologie</term>
<term>Polymère vecteur</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Toxicomanie</term>
<term>Réalité virtuelle</term>
<term>Simulation</term>
<term>Nanotechnologie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">When dealing with nano targeted drug delivery process the significant area of virtual reality application can be visualizing real time process and simulating it at nano-scale, since the effectiveness of a drug primarily depends on the affected cell and targeted doze. This paper proposes virtual reality (VR) as a tool to analyze and simulate nanoparticles (NPs) manipulation, in this paper amorphous NPs are analyzed and simulated in virtual environment. Haptic guides virtualizing the atomic force microscope (AFM) is applied in the virtual environment which allows the operators to sense and touch the NPs when evaluating its structure, drug release time, and behavioral study. Cisplatin was loaded as a modal drug to the self-assembled amorphous copolymer P(3HV-co-4HB)-b-mPEG NPs, where the efficiency and bioavailability of Cisplatin was further investigated. The prepared NPs when simulated in virtual environment proved to show good biocompatibility. Results showed that amorphous polymeric NPs could be efficient vehicles for the constant and targeted delivery of toxic anticancer drugs.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001F37 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 001F37 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Ticri/CIDE |area= HapticV1 |flux= Main |étape= Curation |type= RBID |clé= Pascal:13-0241843 |texte= Haptic Guided Virtual Reality Simulation for Targeted Drug Delivery Using Nano-Containers Manipulation }}
![]() | This area was generated with Dilib version V0.6.23. | ![]() |