Paramagnetic 19F chemical shift probes that respond selectively to calcium or citrate levels and signal ester hydrolysis.
Identifieur interne : 000357 ( PubMed/Corpus ); précédent : 000356; suivant : 000358Paramagnetic 19F chemical shift probes that respond selectively to calcium or citrate levels and signal ester hydrolysis.
Auteurs : Peter Harvey ; Kirsten H. Chalmers ; Elena De Luca ; Anurag Mishra ; David ParkerSource :
- Chemistry (Weinheim an der Bergstrasse, Germany) [ 1521-3765 ] ; 2012.
Abstract
Paramagnetic magnetic resonance chemical shift probes containing a proximal CF(3) group have been characterised. Different systems have been created that report reversible changes in calcium ion concentrations in the millimolar regime, signal the presence of citrate selectively in competitive aqueous media and allow the monitoring of remote ester/amide hydrolysis in relayed, irreversible transformations. Chemical shift non-equivalence is amplified by the presence of the proximate lanthanide ion, with a mean separation between the CF(3) group and the metal ion of 6.4 Å found for a thulium complex, in an X-ray structure of the metal complex aqua adduct. The enhanced rate of longitudinal relaxation of the (19)F nucleus allows faster data acquisition.
DOI: 10.1002/chem.201200737
PubMed: 22689478
Links to Exploration step
pubmed:22689478Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Paramagnetic 19F chemical shift probes that respond selectively to calcium or citrate levels and signal ester hydrolysis.</title><author><name sortKey="Harvey, Peter" sort="Harvey, Peter" uniqKey="Harvey P" first="Peter" last="Harvey">Peter Harvey</name><affiliation><nlm:affiliation>Department of Chemistry, Durham University, South Road, Durham DH1 3LE, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Chalmers, Kirsten H" sort="Chalmers, Kirsten H" uniqKey="Chalmers K" first="Kirsten H" last="Chalmers">Kirsten H. Chalmers</name></author><author><name sortKey="De Luca, Elena" sort="De Luca, Elena" uniqKey="De Luca E" first="Elena" last="De Luca">Elena De Luca</name></author><author><name sortKey="Mishra, Anurag" sort="Mishra, Anurag" uniqKey="Mishra A" first="Anurag" last="Mishra">Anurag Mishra</name></author><author><name sortKey="Parker, David" sort="Parker, David" uniqKey="Parker D" first="David" last="Parker">David Parker</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2012">2012</date><idno type="doi">10.1002/chem.201200737</idno><idno type="RBID">pubmed:22689478</idno><idno type="pmid">22689478</idno><idno type="wicri:Area/PubMed/Corpus">000357</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000357</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Paramagnetic 19F chemical shift probes that respond selectively to calcium or citrate levels and signal ester hydrolysis.</title><author><name sortKey="Harvey, Peter" sort="Harvey, Peter" uniqKey="Harvey P" first="Peter" last="Harvey">Peter Harvey</name><affiliation><nlm:affiliation>Department of Chemistry, Durham University, South Road, Durham DH1 3LE, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Chalmers, Kirsten H" sort="Chalmers, Kirsten H" uniqKey="Chalmers K" first="Kirsten H" last="Chalmers">Kirsten H. Chalmers</name></author><author><name sortKey="De Luca, Elena" sort="De Luca, Elena" uniqKey="De Luca E" first="Elena" last="De Luca">Elena De Luca</name></author><author><name sortKey="Mishra, Anurag" sort="Mishra, Anurag" uniqKey="Mishra A" first="Anurag" last="Mishra">Anurag Mishra</name></author><author><name sortKey="Parker, David" sort="Parker, David" uniqKey="Parker D" first="David" last="Parker">David Parker</name></author></analytic><series><title level="j">Chemistry (Weinheim an der Bergstrasse, Germany)</title><idno type="eISSN">1521-3765</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Paramagnetic magnetic resonance chemical shift probes containing a proximal CF(3) group have been characterised. Different systems have been created that report reversible changes in calcium ion concentrations in the millimolar regime, signal the presence of citrate selectively in competitive aqueous media and allow the monitoring of remote ester/amide hydrolysis in relayed, irreversible transformations. Chemical shift non-equivalence is amplified by the presence of the proximate lanthanide ion, with a mean separation between the CF(3) group and the metal ion of 6.4 Å found for a thulium complex, in an X-ray structure of the metal complex aqua adduct. The enhanced rate of longitudinal relaxation of the (19)F nucleus allows faster data acquisition.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="PubMed-not-MEDLINE"><PMID Version="1">22689478</PMID><DateCreated><Year>2012</Year><Month>07</Month><Day>04</Day></DateCreated><DateCompleted><Year>2012</Year><Month>10</Month><Day>17</Day></DateCompleted><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1521-3765</ISSN><JournalIssue CitedMedium="Internet"><Volume>18</Volume><Issue>28</Issue><PubDate><Year>2012</Year><Month>Jul</Month><Day>9</Day></PubDate></JournalIssue><Title>Chemistry (Weinheim an der Bergstrasse, Germany)</Title><ISOAbbreviation>Chemistry</ISOAbbreviation></Journal><ArticleTitle>Paramagnetic 19F chemical shift probes that respond selectively to calcium or citrate levels and signal ester hydrolysis.</ArticleTitle><Pagination><MedlinePgn>8748-57</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/chem.201200737</ELocationID><Abstract><AbstractText>Paramagnetic magnetic resonance chemical shift probes containing a proximal CF(3) group have been characterised. Different systems have been created that report reversible changes in calcium ion concentrations in the millimolar regime, signal the presence of citrate selectively in competitive aqueous media and allow the monitoring of remote ester/amide hydrolysis in relayed, irreversible transformations. Chemical shift non-equivalence is amplified by the presence of the proximate lanthanide ion, with a mean separation between the CF(3) group and the metal ion of 6.4 Å found for a thulium complex, in an X-ray structure of the metal complex aqua adduct. The enhanced rate of longitudinal relaxation of the (19)F nucleus allows faster data acquisition.</AbstractText><CopyrightInformation>Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Harvey</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Chemistry, Durham University, South Road, Durham DH1 3LE, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chalmers</LastName><ForeName>Kirsten H</ForeName><Initials>KH</Initials></Author><Author ValidYN="Y"><LastName>De Luca</LastName><ForeName>Elena</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Mishra</LastName><ForeName>Anurag</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Parker</LastName><ForeName>David</ForeName><Initials>D</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2012</Year><Month>06</Month><Day>11</Day></ArticleDate></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Chemistry</MedlineTA><NlmUniqueID>9513783</NlmUniqueID><ISSNLinking>0947-6539</ISSNLinking></MedlineJournalInfo></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2012</Year><Month>4</Month><Day>4</Day></PubMedPubDate><PubMedPubDate PubStatus="aheadofprint"><Year>2012</Year><Month>6</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2012</Year><Month>6</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2012</Year><Month>6</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2012</Year><Month>6</Month><Day>13</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="doi">10.1002/chem.201200737</ArticleId><ArticleId IdType="pubmed">22689478</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Terre/explor/ThuliumV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000357 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000357 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Terre
|area= ThuliumV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:22689478
|texte= Paramagnetic 19F chemical shift probes that respond selectively to calcium or citrate levels and signal ester hydrolysis.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:22689478" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a ThuliumV1
| This area was generated with Dilib version V0.6.21. |  |