ThuliumV1, Main, Merge, bibRecord, 003766

Thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate) as a 23Na shift reagent for the in vivo rat liver

Identifieur interne : 003766 ( Main/Merge ); précédent : 003765; suivant : 003767

Thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate) as a 23Na shift reagent for the in vivo rat liver

Auteurs : N. Bansal [États-Unis] ; M. J. Germann [États-Unis] ; V. Seshan [États-Unis] ; G. T. Iii Shires ; C. R. Malloy [États-Unis] ; A. D. Sherry [États-Unis]

Source :

Biochemistry : (Easton) [ 0006-2960 ] ; 1993.

RBID : Pascal:93-0581015

Descripteurs français

Pascal (Inist)
- Réactif déplacement, Spectrométrie RMN, Sodium Ion, Gradient, Temps relaxation, Foie, Rat, In vivo.

English descriptors

KwdEn :
- Gradient, In vivo, Liver, NMR spectrometry, Rat, Relaxation time, Shift reagent, Sodium Ions.

Abstract

The use of thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate (TmDOTP^5-) as an in vivo ²³Na NMR shift reagent for rat liver was evaluated by collecting interleaved ²³Na and ³¹P spectra. Infusion of 80 mM TmDOTP^5- without added Ca²⁺ produced baseline-resolved peaks from intra- and extracellular sodium without producing any changes in phosphate metabolite resonances or intracellular pH. Several key physiological parameters measured in parallel groups of animals confirmed that liver physiology is largely unaffected by this shift reagent

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Pascal:93-0581015

Le document en format XML

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Na shift reagent for the in vivo rat liver</title>
<author><name sortKey="Bansal, N" sort="Bansal, N" uniqKey="Bansal N" first="N." last="Bansal">N. Bansal</name>
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<s2>Dallas TX 75235-9085</s2>
<s3>USA</s3>
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<author><name sortKey="Seshan, V" sort="Seshan, V" uniqKey="Seshan V" first="V." last="Seshan">V. Seshan</name>
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<idno type="wicri:explorRef" wicri:stream="Pascal" wicri:step="Checkpoint">001820</idno>
<idno type="wicri:doubleKey">0006-2960:1993:Bansal N:thulium:tetraazacyclododecane:tetrakis</idno>
<idno type="wicri:Area/Main/Merge">003766</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate) as a <sup>23</sup>
Na shift reagent for the in vivo rat liver</title>
<author><name sortKey="Bansal, N" sort="Bansal, N" uniqKey="Bansal N" first="N." last="Bansal">N. Bansal</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Univ. Texas Southwestern medical cent., Mary Nell Ralph B. Rogers magnetic resonance cent., dep. radiology</s1>
<s2>Dallas TX 75235-9085</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
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<country>États-Unis</country>
<wicri:noRegion>Dallas TX 75235-9085</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Germann, M J" sort="Germann, M J" uniqKey="Germann M" first="M. J." last="Germann">M. J. Germann</name>
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<s2>Dallas TX 75235-9085</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
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<country>États-Unis</country>
<wicri:noRegion>Dallas TX 75235-9085</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Seshan, V" sort="Seshan, V" uniqKey="Seshan V" first="V." last="Seshan">V. Seshan</name>
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<s2>Dallas TX 75235-9085</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Dallas TX 75235-9085</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shires, G T Iii" sort="Shires, G T Iii" uniqKey="Shires G" first="G. T. Iii" last="Shires">G. T. Iii Shires</name>
</author>
<author><name sortKey="Malloy, C R" sort="Malloy, C R" uniqKey="Malloy C" first="C. R." last="Malloy">C. R. Malloy</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Univ. Texas Southwestern medical cent., Mary Nell Ralph B. Rogers magnetic resonance cent., dep. radiology</s1>
<s2>Dallas TX 75235-9085</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
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<country>États-Unis</country>
<wicri:noRegion>Dallas TX 75235-9085</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sherry, A D" sort="Sherry, A D" uniqKey="Sherry A" first="A. D." last="Sherry">A. D. Sherry</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Univ. Texas Southwestern medical cent., Mary Nell Ralph B. Rogers magnetic resonance cent., dep. radiology</s1>
<s2>Dallas TX 75235-9085</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
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<country>États-Unis</country>
<wicri:noRegion>Dallas TX 75235-9085</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Biochemistry : (Easton)</title>
<title level="j" type="abbreviated">Biochemistry : (Easton)</title>
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<seriesStmt><title level="j" type="main">Biochemistry : (Easton)</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Gradient</term>
<term>In vivo</term>
<term>Liver</term>
<term>NMR spectrometry</term>
<term>Rat</term>
<term>Relaxation time</term>
<term>Shift reagent</term>
<term>Sodium Ions</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Réactif déplacement</term>
<term>Spectrométrie RMN</term>
<term>Sodium Ion</term>
<term>Gradient</term>
<term>Temps relaxation</term>
<term>Foie</term>
<term>Rat</term>
<term>In vivo</term>
</keywords>
</textClass>
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</teiHeader>
<front><div type="abstract" xml:lang="en">The use of thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate (TmDOTP<sup>5-</sup>
) as an in vivo <sup>23</sup>
Na NMR shift reagent for rat liver was evaluated by collecting interleaved <sup>23</sup>
Na and <sup>31</sup>
P spectra. Infusion of 80 mM TmDOTP<sup>5-</sup>
 without added Ca<sup>2+</sup>
 produced baseline-resolved peaks from intra- and extracellular sodium without producing any changes in phosphate metabolite resonances or intracellular pH. Several key physiological parameters measured in parallel groups of animals confirmed that liver physiology is largely unaffected by this shift reagent</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
</list>
<tree><noCountry><name sortKey="Shires, G T Iii" sort="Shires, G T Iii" uniqKey="Shires G" first="G. T. Iii" last="Shires">G. T. Iii Shires</name>
</noCountry>
<country name="États-Unis"><noRegion><name sortKey="Bansal, N" sort="Bansal, N" uniqKey="Bansal N" first="N." last="Bansal">N. Bansal</name>
</noRegion>
<name sortKey="Germann, M J" sort="Germann, M J" uniqKey="Germann M" first="M. J." last="Germann">M. J. Germann</name>
<name sortKey="Malloy, C R" sort="Malloy, C R" uniqKey="Malloy C" first="C. R." last="Malloy">C. R. Malloy</name>
<name sortKey="Seshan, V" sort="Seshan, V" uniqKey="Seshan V" first="V." last="Seshan">V. Seshan</name>
<name sortKey="Sherry, A D" sort="Sherry, A D" uniqKey="Sherry A" first="A. D." last="Sherry">A. D. Sherry</name>
</country>
</tree>
</affiliations>
</record>

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Thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate) as a 23Na shift reagent for the in vivo rat liver

Thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate) as a 23Na shift reagent for the in vivo rat liver

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri