ThuliumV1, Main, Exploration, bibRecordById, pubmed:8841530

Lanthanide or transition metal ions-mediated cleavage of DNA by hydroxamic acid derivative.

Identifieur interne : 002E64 ( Main/Exploration ); précédent : 002E63; suivant : 002E65

Lanthanide or transition metal ions-mediated cleavage of DNA by hydroxamic acid derivative.

Auteurs : S. Hashimoto [Japon] ; Y. Nakamura

Source :

Nucleic acids symposium series [ 0261-3166 ] ; 1995.

RBID : pubmed:8841530

Descripteurs français

KwdFr :
- ADN bactérien (), ADN bactérien (isolement et purification), Acides hydroxamiques, Espèces réactives de l'oxygène, Métaux, Piégeurs de radicaux libres, Plasmides (), Plasmides (isolement et purification), Structure moléculaire, Terres rares, Électrophorèse sur gel d'agar.
MESH :
- isolement et purification : ADN bactérien, Plasmides.
- ADN bactérien, Acides hydroxamiques, Espèces réactives de l'oxygène, Métaux, Piégeurs de radicaux libres, Plasmides, Structure moléculaire, Terres rares, Électrophorèse sur gel d'agar.

English descriptors

KwdEn :
- DNA, Bacterial (chemistry), DNA, Bacterial (isolation & purification), Electrophoresis, Agar Gel, Free Radical Scavengers, Hydroxamic Acids, Metals, Metals, Rare Earth, Molecular Structure, Plasmids (chemistry), Plasmids (isolation & purification), Reactive Oxygen Species.
MESH :
- chemical , chemistry : DNA, Bacterial.
- chemical , isolation & purification : DNA, Bacterial.
- chemistry : Plasmids.
- isolation & purification : Plasmids.
- Electrophoresis, Agar Gel, Free Radical Scavengers, Hydroxamic Acids, Metals, Metals, Rare Earth, Molecular Structure, Reactive Oxygen Species.

Abstract

N-[5-(hydroxylaminocarbonyl)pentyl]phenanthridium chloride 1 has been shown to induce cleavage of ColE1 DNA in the presence of transition (ferrous, ferric and vanadyl) or lanthanide(III) (lutetium, thulium and europium) metal ions. The addition of free radical scavengers inhibits the former reaction, but does not the latter case.

PubMed: 8841530

Affiliations:

Japon

Le document en format XML

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<author><name sortKey="Hashimoto, S" sort="Hashimoto, S" uniqKey="Hashimoto S" first="S" last="Hashimoto">S. Hashimoto</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biological Science and Technology, Science University of Tokyo, Chiba, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Biological Science and Technology, Science University of Tokyo, Chiba</wicri:regionArea>
<wicri:noRegion>Chiba</wicri:noRegion>
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<author><name sortKey="Nakamura, Y" sort="Nakamura, Y" uniqKey="Nakamura Y" first="Y" last="Nakamura">Y. Nakamura</name>
</author>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Lanthanide or transition metal ions-mediated cleavage of DNA by hydroxamic acid derivative.</title>
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<series><title level="j">Nucleic acids symposium series</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>DNA, Bacterial (chemistry)</term>
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<term>Electrophoresis, Agar Gel</term>
<term>Free Radical Scavengers</term>
<term>Hydroxamic Acids</term>
<term>Metals</term>
<term>Metals, Rare Earth</term>
<term>Molecular Structure</term>
<term>Plasmids (chemistry)</term>
<term>Plasmids (isolation & purification)</term>
<term>Reactive Oxygen Species</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>ADN bactérien ()</term>
<term>ADN bactérien (isolement et purification)</term>
<term>Acides hydroxamiques</term>
<term>Espèces réactives de l'oxygène</term>
<term>Métaux</term>
<term>Piégeurs de radicaux libres</term>
<term>Plasmides ()</term>
<term>Plasmides (isolement et purification)</term>
<term>Structure moléculaire</term>
<term>Terres rares</term>
<term>Électrophorèse sur gel d'agar</term>
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<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>DNA, Bacterial</term>
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<keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>DNA, Bacterial</term>
</keywords>
<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Plasmids</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Plasmids</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>ADN bactérien</term>
<term>Plasmides</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Electrophoresis, Agar Gel</term>
<term>Free Radical Scavengers</term>
<term>Hydroxamic Acids</term>
<term>Metals</term>
<term>Metals, Rare Earth</term>
<term>Molecular Structure</term>
<term>Reactive Oxygen Species</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>ADN bactérien</term>
<term>Acides hydroxamiques</term>
<term>Espèces réactives de l'oxygène</term>
<term>Métaux</term>
<term>Piégeurs de radicaux libres</term>
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<term>Terres rares</term>
<term>Électrophorèse sur gel d'agar</term>
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<front><div type="abstract" xml:lang="en">N-[5-(hydroxylaminocarbonyl)pentyl]phenanthridium chloride 1 has been shown to induce cleavage of ColE1 DNA in the presence of transition (ferrous, ferric and vanadyl) or lanthanide(III) (lutetium, thulium and europium) metal ions. The addition of free radical scavengers inhibits the former reaction, but does not the latter case.</div>
</front>
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<tree><noCountry><name sortKey="Nakamura, Y" sort="Nakamura, Y" uniqKey="Nakamura Y" first="Y" last="Nakamura">Y. Nakamura</name>
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<country name="Japon"><noRegion><name sortKey="Hashimoto, S" sort="Hashimoto, S" uniqKey="Hashimoto S" first="S" last="Hashimoto">S. Hashimoto</name>
</noRegion>
</country>
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</affiliations>
</record>

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Lanthanide or transition metal ions-mediated cleavage of DNA by hydroxamic acid derivative.

Lanthanide or transition metal ions-mediated cleavage of DNA by hydroxamic acid derivative.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

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