Lanthanide or transition metal ions-mediated cleavage of DNA by hydroxamic acid derivative.
Identifieur interne : 000769 ( PubMed/Corpus ); précédent : 000768; suivant : 000770Lanthanide or transition metal ions-mediated cleavage of DNA by hydroxamic acid derivative.
Auteurs : S. Hashimoto ; Y. NakamuraSource :
- Nucleic acids symposium series [ 0261-3166 ] ; 1995.
English descriptors
- KwdEn :
- MESH :
- chemical , chemistry : DNA, Bacterial.
- chemical , isolation & purification : DNA, Bacterial.
- chemistry : Plasmids.
- isolation & purification : Plasmids.
- Electrophoresis, Agar Gel, Free Radical Scavengers, Hydroxamic Acids, Metals, Metals, Rare Earth, Molecular Structure, Reactive Oxygen Species.
Abstract
N-[5-(hydroxylaminocarbonyl)pentyl]phenanthridium chloride 1 has been shown to induce cleavage of ColE1 DNA in the presence of transition (ferrous, ferric and vanadyl) or lanthanide(III) (lutetium, thulium and europium) metal ions. The addition of free radical scavengers inhibits the former reaction, but does not the latter case.
PubMed: 8841530
Links to Exploration step
pubmed:8841530Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lanthanide or transition metal ions-mediated cleavage of DNA by hydroxamic acid derivative.</title><author><name sortKey="Hashimoto, S" sort="Hashimoto, S" uniqKey="Hashimoto S" first="S" last="Hashimoto">S. Hashimoto</name><affiliation><nlm:affiliation>Department of Biological Science and Technology, Science University of Tokyo, Chiba, Japan.</nlm:affiliation></affiliation></author><author><name sortKey="Nakamura, Y" sort="Nakamura, Y" uniqKey="Nakamura Y" first="Y" last="Nakamura">Y. Nakamura</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1995">1995</date><idno type="RBID">pubmed:8841530</idno><idno type="pmid">8841530</idno><idno type="wicri:Area/PubMed/Corpus">000769</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000769</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Lanthanide or transition metal ions-mediated cleavage of DNA by hydroxamic acid derivative.</title><author><name sortKey="Hashimoto, S" sort="Hashimoto, S" uniqKey="Hashimoto S" first="S" last="Hashimoto">S. Hashimoto</name><affiliation><nlm:affiliation>Department of Biological Science and Technology, Science University of Tokyo, Chiba, Japan.</nlm:affiliation></affiliation></author><author><name sortKey="Nakamura, Y" sort="Nakamura, Y" uniqKey="Nakamura Y" first="Y" last="Nakamura">Y. Nakamura</name></author></analytic><series><title level="j">Nucleic acids symposium series</title><idno type="ISSN">0261-3166</idno><imprint><date when="1995" type="published">1995</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>DNA, Bacterial (chemistry)</term><term>DNA, Bacterial (isolation & purification)</term><term>Electrophoresis, Agar Gel</term><term>Free Radical Scavengers</term><term>Hydroxamic Acids</term><term>Metals</term><term>Metals, Rare Earth</term><term>Molecular Structure</term><term>Plasmids (chemistry)</term><term>Plasmids (isolation & purification)</term><term>Reactive Oxygen Species</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>DNA, Bacterial</term></keywords><keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>DNA, Bacterial</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Plasmids</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Plasmids</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Electrophoresis, Agar Gel</term><term>Free Radical Scavengers</term><term>Hydroxamic Acids</term><term>Metals</term><term>Metals, Rare Earth</term><term>Molecular Structure</term><term>Reactive Oxygen Species</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">N-[5-(hydroxylaminocarbonyl)pentyl]phenanthridium chloride 1 has been shown to induce cleavage of ColE1 DNA in the presence of transition (ferrous, ferric and vanadyl) or lanthanide(III) (lutetium, thulium and europium) metal ions. The addition of free radical scavengers inhibits the former reaction, but does not the latter case.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">8841530</PMID><DateCreated><Year>1996</Year><Month>12</Month><Day>18</Day></DateCreated><DateCompleted><Year>1996</Year><Month>12</Month><Day>18</Day></DateCompleted><DateRevised><Year>2006</Year><Month>05</Month><Day>01</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0261-3166</ISSN><JournalIssue CitedMedium="Print"><Issue>34</Issue><PubDate><Year>1995</Year></PubDate></JournalIssue><Title>Nucleic acids symposium series</Title><ISOAbbreviation>Nucleic Acids Symp. Ser.</ISOAbbreviation></Journal><ArticleTitle>Lanthanide or transition metal ions-mediated cleavage of DNA by hydroxamic acid derivative.</ArticleTitle><Pagination><MedlinePgn>17-8</MedlinePgn></Pagination><Abstract><AbstractText>N-[5-(hydroxylaminocarbonyl)pentyl]phenanthridium chloride 1 has been shown to induce cleavage of ColE1 DNA in the presence of transition (ferrous, ferric and vanadyl) or lanthanide(III) (lutetium, thulium and europium) metal ions. The addition of free radical scavengers inhibits the former reaction, but does not the latter case.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hashimoto</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Biological Science and Technology, Science University of Tokyo, Chiba, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nakamura</LastName><ForeName>Y</ForeName><Initials>Y</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>ENGLAND</Country><MedlineTA>Nucleic Acids Symp Ser</MedlineTA><NlmUniqueID>8007206</NlmUniqueID><ISSNLinking>0261-3166</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D004269">DNA, Bacterial</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D016166">Free Radical Scavengers</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D006877">Hydroxamic Acids</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008670">Metals</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008674">Metals, Rare Earth</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D017382">Reactive Oxygen Species</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004269">DNA, Bacterial</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000737">chemistry</QualifierName><QualifierName MajorTopicYN="N" UI="Q000302">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004587">Electrophoresis, Agar Gel</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016166">Free Radical Scavengers</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006877">Hydroxamic Acids</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008670">Metals</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008674">Metals, Rare Earth</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D015394">Molecular Structure</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010957">Plasmids</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000737">chemistry</QualifierName><QualifierName MajorTopicYN="N" UI="Q000302">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D017382">Reactive Oxygen Species</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1995</Year><Month>1</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1995</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1995</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">8841530</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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