ThuliumV1, Main, Exploration, bibRecordById, pubmed:25536114

Near infrared activation of an anticancer Pt(IV) complex by Tm-doped upconversion nanoparticles.

Identifieur interne : 000121 ( Main/Exploration ); précédent : 000120; suivant : 000122

Near infrared activation of an anticancer Pt(IV) complex by Tm-doped upconversion nanoparticles.

Auteurs : Emmanuel Ruggiero [Espagne] ; Javier Hernández-Gil ; Juan C. Mareque-Rivas ; Luca Salassa

Source :

Chemical communications (Cambridge, England) [ 1364-548X ] ; 2015.

RBID : pubmed:25536114

Descripteurs français

KwdFr :
- Antinéoplasiques (), Composés organiques du platine (), Nanoparticules (), Photolyse, Promédicaments (), Rayons infrarouges, Thulium ().
MESH :
- Antinéoplasiques, Composés organiques du platine, Nanoparticules, Photolyse, Promédicaments, Rayons infrarouges, Thulium.

English descriptors

KwdEn :
- Antineoplastic Agents (chemistry), Infrared Rays, Nanoparticles (chemistry), Organoplatinum Compounds (chemistry), Photolysis, Prodrugs (chemistry), Thulium (chemistry).
MESH :
- chemical , chemistry : Antineoplastic Agents, Organoplatinum Compounds, Prodrugs, Thulium.
- chemistry : Nanoparticles.
- Infrared Rays, Photolysis.

Abstract

The Pt(IV) complex cis,cis,trans-[Pt(NH3)2(Cl)2(O2CCH2CH2CO2H)2] is photoactivated by near infrared light (980 nm) using NaYF4:Yb(3+)/Tm(3+)@NaYF4 core-shell upconversion nanoparticles. Coupling of this cisplatin precursor with the biocompatible PEGylated phospholipid DSPE-PEG(2000)-NH2 affords a valuable approach to decorate the surface of the nanoparticles, providing novel photoactivatable nanomaterials capable of releasing Pt(II) species upon NIR light excitation.

DOI: 10.1039/c4cc07960d
PubMed: 25536114

Affiliations:

Espagne

Le document en format XML

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<author><name sortKey="Ruggiero, Emmanuel" sort="Ruggiero, Emmanuel" uniqKey="Ruggiero E" first="Emmanuel" last="Ruggiero">Emmanuel Ruggiero</name>
<affiliation wicri:level="1"><nlm:affiliation>CIC biomaGUNE, Paseo de Miramón 182, 20009, Donostia, Euskadi, Spain. lsalassa@cicbiomagune.es.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
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<wicri:noRegion>Euskadi</wicri:noRegion>
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<author><name sortKey="Hernandez Gil, Javier" sort="Hernandez Gil, Javier" uniqKey="Hernandez Gil J" first="Javier" last="Hernández-Gil">Javier Hernández-Gil</name>
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<author><name sortKey="Mareque Rivas, Juan C" sort="Mareque Rivas, Juan C" uniqKey="Mareque Rivas J" first="Juan C" last="Mareque-Rivas">Juan C. Mareque-Rivas</name>
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<author><name sortKey="Salassa, Luca" sort="Salassa, Luca" uniqKey="Salassa L" first="Luca" last="Salassa">Luca Salassa</name>
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<author><name sortKey="Hernandez Gil, Javier" sort="Hernandez Gil, Javier" uniqKey="Hernandez Gil J" first="Javier" last="Hernández-Gil">Javier Hernández-Gil</name>
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<author><name sortKey="Mareque Rivas, Juan C" sort="Mareque Rivas, Juan C" uniqKey="Mareque Rivas J" first="Juan C" last="Mareque-Rivas">Juan C. Mareque-Rivas</name>
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<term>Photolysis</term>
<term>Prodrugs (chemistry)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Antinéoplasiques ()</term>
<term>Composés organiques du platine ()</term>
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<term>Photolyse</term>
<term>Promédicaments ()</term>
<term>Rayons infrarouges</term>
<term>Thulium ()</term>
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<term>Organoplatinum Compounds</term>
<term>Prodrugs</term>
<term>Thulium</term>
</keywords>
<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Nanoparticles</term>
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<term>Composés organiques du platine</term>
<term>Nanoparticules</term>
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<term>Promédicaments</term>
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<front><div type="abstract" xml:lang="en">The Pt(IV) complex cis,cis,trans-[Pt(NH3)2(Cl)2(O2CCH2CH2CO2H)2] is photoactivated by near infrared light (980 nm) using NaYF4:Yb(3+)/Tm(3+)@NaYF4 core-shell upconversion nanoparticles. Coupling of this cisplatin precursor with the biocompatible PEGylated phospholipid DSPE-PEG(2000)-NH2 affords a valuable approach to decorate the surface of the nanoparticles, providing novel photoactivatable nanomaterials capable of releasing Pt(II) species upon NIR light excitation.</div>
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<name sortKey="Salassa, Luca" sort="Salassa, Luca" uniqKey="Salassa L" first="Luca" last="Salassa">Luca Salassa</name>
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<country name="Espagne"><noRegion><name sortKey="Ruggiero, Emmanuel" sort="Ruggiero, Emmanuel" uniqKey="Ruggiero E" first="Emmanuel" last="Ruggiero">Emmanuel Ruggiero</name>
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Near infrared activation of an anticancer Pt(IV) complex by Tm-doped upconversion nanoparticles.

Near infrared activation of an anticancer Pt(IV) complex by Tm-doped upconversion nanoparticles.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le thulium
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