Thulium:YAG VapoEnucleation of the prostate in large glands: a prospective comparison using 70- and 120-W 2-µm lasers
Identifieur interne : 000700 ( Main/Exploration ); précédent : 000699; suivant : 000701Thulium:YAG VapoEnucleation of the prostate in large glands: a prospective comparison using 70- and 120-W 2-µm lasers
Auteurs : Christopher Netsch [Allemagne] ; Thorsten Bach [Allemagne] ; Thomas Rw Herrmann [Allemagne] ; Andreas J. Gross [Allemagne]Source :
- Asian Journal of Andrology [ 1008-682X ] ; 2012.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Humains, Hyperplasie de la prostate (), Hyperplasie de la prostate (anatomopathologie), Lasers à solide (effets indésirables), Lasers à solide (usage thérapeutique), Mâle, Prostate (), Prostate (anatomopathologie), Qualité de vie, Résultat thérapeutique, Rétention d'urine, Sujet âgé, Sujet âgé de 80 ans ou plus, Taille d'organe, Thulium, Études de suivi, Études prospectives.
- MESH :
- anatomopathologie : Hyperplasie de la prostate, Prostate.
- effets indésirables : Lasers à solide.
- usage thérapeutique : Lasers à solide.
- Adulte d'âge moyen, Humains, Hyperplasie de la prostate, Mâle, Prostate, Qualité de vie, Résultat thérapeutique, Rétention d'urine, Sujet âgé, Sujet âgé de 80 ans ou plus, Taille d'organe, Thulium, Études de suivi, Études prospectives.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Follow-Up Studies, Humans, Lasers, Solid-State (adverse effects), Lasers, Solid-State (therapeutic use), Male, Middle Aged, Organ Size, Prospective Studies, Prostate (pathology), Prostate (surgery), Prostatic Hyperplasia (pathology), Prostatic Hyperplasia (surgery), Quality of Life, Thulium, Treatment Outcome, Urinary Retention.
- MESH :
- chemical : Thulium.
- adverse effects : Lasers, Solid-State.
- pathology : Prostate, Prostatic Hyperplasia.
- surgery : Prostate, Prostatic Hyperplasia.
- therapeutic use : Lasers, Solid-State.
- Aged, Aged, 80 and over, Follow-Up Studies, Humans, Male, Middle Aged, Organ Size, Prospective Studies, Quality of Life, Treatment Outcome, Urinary Retention.
Abstract
This study compared the efficacy of 70- and 120-w 2-µm thulium:YAG VapoEnucleation of the prostate (ThuVEP) for patients with benign prostatic obstruction (BPO). A prospective analysis of 84 patients with symptomatic BPO and prostatic enlargement (≥60 ml) who underwent either 70-w (
Url:
DOI: 10.1038/aja.2011.167
PubMed: 22231295
PubMed Central: 3735080
Affiliations:
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Le document en format XML
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<term>Aged, 80 and over</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Lasers, Solid-State (adverse effects)</term>
<term>Lasers, Solid-State (therapeutic use)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Organ Size</term>
<term>Prospective Studies</term>
<term>Prostate (pathology)</term>
<term>Prostate (surgery)</term>
<term>Prostatic Hyperplasia (pathology)</term>
<term>Prostatic Hyperplasia (surgery)</term>
<term>Quality of Life</term>
<term>Thulium</term>
<term>Treatment Outcome</term>
<term>Urinary Retention</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Humains</term>
<term>Hyperplasie de la prostate ()</term>
<term>Hyperplasie de la prostate (anatomopathologie)</term>
<term>Lasers à solide (effets indésirables)</term>
<term>Lasers à solide (usage thérapeutique)</term>
<term>Mâle</term>
<term>Prostate ()</term>
<term>Prostate (anatomopathologie)</term>
<term>Qualité de vie</term>
<term>Résultat thérapeutique</term>
<term>Rétention d'urine</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Taille d'organe</term>
<term>Thulium</term>
<term>Études de suivi</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Thulium</term>
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<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Lasers, Solid-State</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Hyperplasie de la prostate</term>
<term>Prostate</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Lasers à solide</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Prostate</term>
<term>Prostatic Hyperplasia</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Prostate</term>
<term>Prostatic Hyperplasia</term>
</keywords>
<keywords scheme="MESH" qualifier="therapeutic use" xml:lang="en"><term>Lasers, Solid-State</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Lasers à solide</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Organ Size</term>
<term>Prospective Studies</term>
<term>Quality of Life</term>
<term>Treatment Outcome</term>
<term>Urinary Retention</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Humains</term>
<term>Hyperplasie de la prostate</term>
<term>Mâle</term>
<term>Prostate</term>
<term>Qualité de vie</term>
<term>Résultat thérapeutique</term>
<term>Rétention d'urine</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Taille d'organe</term>
<term>Thulium</term>
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<term>Études prospectives</term>
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<front><div type="abstract" xml:lang="en"><p>This study compared the efficacy of 70- and 120-w 2-µm thulium:YAG VapoEnucleation of the prostate (ThuVEP) for patients with benign prostatic obstruction (BPO). A prospective analysis of 84 patients with symptomatic BPO and prostatic enlargement (≥60 ml) who underwent either 70-w (<italic>n</italic>
=44) or 120-w ThuVEP (<italic>n</italic>
=40) non-randomly was carried out. Patient demographics and perioperative and 12-month follow-up data were analysed. The mean prostate volume was 79.90±27.49 ml in patients who had received 70-w ThuVEP, which was less than in those who had received 120-w ThuVEP (88.53±25.10; <italic>P</italic>
=0.033). The mean enucleation (resected weight/laser time, 2.16±1.21 g min<sup>−1</sup>
<italic>vs.</italic>
1.23±0.60 g min<sup>−1</sup>
; <italic>P</italic>
=0.013), operation efficiency (resected weight/total operation time, 0.76±0.35 g min<sup>−1</sup>
<italic>vs.</italic>
0.42±0.27 g min<sup>−1</sup>
; <italic>P</italic>
=0.000) and percentage of resected tissue (66.93%±22.79% <italic>vs.</italic>
45.41%±23.33% <italic>P</italic>
=0.000) were higher with 120-w treatment compared to 70-w ThuVEP. One patient (1.2% of total patients) (in the 120-w group) required a blood transfusion postoperatively. Sixty-one patients (73%) were available for review at the 12-month follow-up time point. The quality of life (QoL), International Prostate Symptom Score (IPSS), maximum urinary flow rate (<italic>Q</italic>
<sub>max</sub>
), postvoiding residual urine (PVR) and prostate volume improved significantly after treatment (<italic>P</italic>
≤0.035) and were not significantly different between those treated with the different devices (70- and 120-w). The median prostate volume reduction was 81.70% and 82.19% with 70- and 120-w ThuVEP, respectively. The incidence of complications was low and did not differ between groups treated with the different devices. Two patients (2.4%) (one per group) had a bladder neck contracture at the follow-up. ThuVEP is a safe and efficacious procedure for the treatment of symptomatic BPO. The incidence of complications was low with both devices. The 120-w thulium:YAG device enhances the effectiveness of ThuVEP with regard to the percentage of resected tissue and the enucleation/operation efficiency.</p>
</div>
</front>
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<affiliations><list><country><li>Allemagne</li>
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<name sortKey="Bach, Thorsten" sort="Bach, Thorsten" uniqKey="Bach T" first="Thorsten" last="Bach">Thorsten Bach</name>
<name sortKey="Gross, Andreas J" sort="Gross, Andreas J" uniqKey="Gross A" first="Andreas J" last="Gross">Andreas J. Gross</name>
<name sortKey="Herrmann, Thomas Rw" sort="Herrmann, Thomas Rw" uniqKey="Herrmann T" first="Thomas Rw" last="Herrmann">Thomas Rw Herrmann</name>
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