Thulium:YAG VapoEnucleation of the prostate in large glands: a prospective comparison using 70- and 120-W 2-µm lasers
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Auteurs : Christopher Netsch [Allemagne] ; Thorsten Bach [Allemagne] ; Thomas Rw Herrmann [Allemagne] ; Andreas J. Gross [Allemagne]Source :
- Asian Journal of Andrology [ 1008-682X ] ; 2012.
Abstract
This study compared the efficacy of 70- and 120-w 2-µm thulium:YAG VapoEnucleation of the prostate (ThuVEP) for patients with benign prostatic obstruction (BPO). A prospective analysis of 84 patients with symptomatic BPO and prostatic enlargement (≥60 ml) who underwent either 70-w (
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DOI: 10.1038/aja.2011.167
PubMed: 22231295
PubMed Central: 3735080
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<author><name sortKey="Netsch, Christopher" sort="Netsch, Christopher" uniqKey="Netsch C" first="Christopher" last="Netsch">Christopher Netsch</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Urology, Asklepios Hospital Barmbek</institution>
, Hamburg 22291,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Bach, Thorsten" sort="Bach, Thorsten" uniqKey="Bach T" first="Thorsten" last="Bach">Thorsten Bach</name>
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, Hamburg 22291,<country>Germany</country>
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<country xml:lang="fr">Allemagne</country>
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<author><name sortKey="Herrmann, Thomas Rw" sort="Herrmann, Thomas Rw" uniqKey="Herrmann T" first="Thomas Rw" last="Herrmann">Thomas Rw Herrmann</name>
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, Hannover 30625,<country>Germany</country>
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<country xml:lang="fr">Allemagne</country>
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<author><name sortKey="Gross, Andreas J" sort="Gross, Andreas J" uniqKey="Gross A" first="Andreas J" last="Gross">Andreas J. Gross</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Thulium:YAG VapoEnucleation of the prostate in large glands: a prospective comparison using 70- and 120-W 2-µm lasers</title>
<author><name sortKey="Netsch, Christopher" sort="Netsch, Christopher" uniqKey="Netsch C" first="Christopher" last="Netsch">Christopher Netsch</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Urology, Asklepios Hospital Barmbek</institution>
, Hamburg 22291,<country>Germany</country>
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<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Bach, Thorsten" sort="Bach, Thorsten" uniqKey="Bach T" first="Thorsten" last="Bach">Thorsten Bach</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Urology, Asklepios Hospital Barmbek</institution>
, Hamburg 22291,<country>Germany</country>
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<country xml:lang="fr">Allemagne</country>
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<author><name sortKey="Herrmann, Thomas Rw" sort="Herrmann, Thomas Rw" uniqKey="Herrmann T" first="Thomas Rw" last="Herrmann">Thomas Rw Herrmann</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Urology, MHH Medical School of Hannover</institution>
, Hannover 30625,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Gross, Andreas J" sort="Gross, Andreas J" uniqKey="Gross A" first="Andreas J" last="Gross">Andreas J. Gross</name>
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, Hamburg 22291,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<series><title level="j">Asian Journal of Andrology</title>
<idno type="ISSN">1008-682X</idno>
<idno type="eISSN">1745-7262</idno>
<imprint><date when="2012">2012</date>
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<front><div type="abstract" xml:lang="en"><p>This study compared the efficacy of 70- and 120-w 2-µm thulium:YAG VapoEnucleation of the prostate (ThuVEP) for patients with benign prostatic obstruction (BPO). A prospective analysis of 84 patients with symptomatic BPO and prostatic enlargement (≥60 ml) who underwent either 70-w (<italic>n</italic>
=44) or 120-w ThuVEP (<italic>n</italic>
=40) non-randomly was carried out. Patient demographics and perioperative and 12-month follow-up data were analysed. The mean prostate volume was 79.90±27.49 ml in patients who had received 70-w ThuVEP, which was less than in those who had received 120-w ThuVEP (88.53±25.10; <italic>P</italic>
=0.033). The mean enucleation (resected weight/laser time, 2.16±1.21 g min<sup>−1</sup>
<italic>vs.</italic>
1.23±0.60 g min<sup>−1</sup>
; <italic>P</italic>
=0.013), operation efficiency (resected weight/total operation time, 0.76±0.35 g min<sup>−1</sup>
<italic>vs.</italic>
0.42±0.27 g min<sup>−1</sup>
; <italic>P</italic>
=0.000) and percentage of resected tissue (66.93%±22.79% <italic>vs.</italic>
45.41%±23.33% <italic>P</italic>
=0.000) were higher with 120-w treatment compared to 70-w ThuVEP. One patient (1.2% of total patients) (in the 120-w group) required a blood transfusion postoperatively. Sixty-one patients (73%) were available for review at the 12-month follow-up time point. The quality of life (QoL), International Prostate Symptom Score (IPSS), maximum urinary flow rate (<italic>Q</italic>
<sub>max</sub>
), postvoiding residual urine (PVR) and prostate volume improved significantly after treatment (<italic>P</italic>
≤0.035) and were not significantly different between those treated with the different devices (70- and 120-w). The median prostate volume reduction was 81.70% and 82.19% with 70- and 120-w ThuVEP, respectively. The incidence of complications was low and did not differ between groups treated with the different devices. Two patients (2.4%) (one per group) had a bladder neck contracture at the follow-up. ThuVEP is a safe and efficacious procedure for the treatment of symptomatic BPO. The incidence of complications was low with both devices. The 120-w thulium:YAG device enhances the effectiveness of ThuVEP with regard to the percentage of resected tissue and the enucleation/operation efficiency.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Asian J Androl</journal-id>
<journal-id journal-id-type="iso-abbrev">Asian J. Androl</journal-id>
<journal-title-group><journal-title>Asian Journal of Andrology</journal-title>
</journal-title-group>
<issn pub-type="ppub">1008-682X</issn>
<issn pub-type="epub">1745-7262</issn>
<publisher><publisher-name>Nature Publishing Group</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">22231295</article-id>
<article-id pub-id-type="pmc">3735080</article-id>
<article-id pub-id-type="pii">aja2011167</article-id>
<article-id pub-id-type="doi">10.1038/aja.2011.167</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Thulium:YAG VapoEnucleation of the prostate in large glands: a prospective comparison using 70- and 120-W 2-µm lasers</article-title>
<alt-title alt-title-type="running">Seventy- and 120-w 2-µm Tm:YAG VapoEnucleation</alt-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Netsch</surname>
<given-names>Christopher</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bach</surname>
<given-names>Thorsten</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Herrmann</surname>
<given-names>Thomas RW</given-names>
</name>
<xref ref-type="aff" rid="aff2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gross</surname>
<given-names>Andreas J</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<aff id="aff1"><label>1</label>
<institution>Department of Urology, Asklepios Hospital Barmbek</institution>
, Hamburg 22291,<country>Germany</country>
</aff>
<aff id="aff2"><label>2</label>
<institution>Department of Urology, MHH Medical School of Hannover</institution>
, Hannover 30625,<country>Germany</country>
</aff>
</contrib-group>
<author-notes><corresp id="caf1"><label>*</label>
(<email>c.netsch@asklepios.com</email>
)</corresp>
</author-notes>
<pub-date pub-type="ppub"><month>03</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="epub"><day>09</day>
<month>01</month>
<year>2012</year>
</pub-date>
<volume>14</volume>
<issue>2</issue>
<fpage>325</fpage>
<lpage>329</lpage>
<history><date date-type="received"><day>09</day>
<month>08</month>
<year>2011</year>
</date>
<date date-type="rev-recd"><day>23</day>
<month>09</month>
<year>2011</year>
</date>
<date date-type="accepted"><day>19</day>
<month>10</month>
<year>2011</year>
</date>
</history>
<permissions><copyright-statement>Copyright © 2012 SIMM & SJTU</copyright-statement>
<copyright-year>2012</copyright-year>
<copyright-holder>SIMM & SJTU</copyright-holder>
</permissions>
<abstract><p>This study compared the efficacy of 70- and 120-w 2-µm thulium:YAG VapoEnucleation of the prostate (ThuVEP) for patients with benign prostatic obstruction (BPO). A prospective analysis of 84 patients with symptomatic BPO and prostatic enlargement (≥60 ml) who underwent either 70-w (<italic>n</italic>
=44) or 120-w ThuVEP (<italic>n</italic>
=40) non-randomly was carried out. Patient demographics and perioperative and 12-month follow-up data were analysed. The mean prostate volume was 79.90±27.49 ml in patients who had received 70-w ThuVEP, which was less than in those who had received 120-w ThuVEP (88.53±25.10; <italic>P</italic>
=0.033). The mean enucleation (resected weight/laser time, 2.16±1.21 g min<sup>−1</sup>
<italic>vs.</italic>
1.23±0.60 g min<sup>−1</sup>
; <italic>P</italic>
=0.013), operation efficiency (resected weight/total operation time, 0.76±0.35 g min<sup>−1</sup>
<italic>vs.</italic>
0.42±0.27 g min<sup>−1</sup>
; <italic>P</italic>
=0.000) and percentage of resected tissue (66.93%±22.79% <italic>vs.</italic>
45.41%±23.33% <italic>P</italic>
=0.000) were higher with 120-w treatment compared to 70-w ThuVEP. One patient (1.2% of total patients) (in the 120-w group) required a blood transfusion postoperatively. Sixty-one patients (73%) were available for review at the 12-month follow-up time point. The quality of life (QoL), International Prostate Symptom Score (IPSS), maximum urinary flow rate (<italic>Q</italic>
<sub>max</sub>
), postvoiding residual urine (PVR) and prostate volume improved significantly after treatment (<italic>P</italic>
≤0.035) and were not significantly different between those treated with the different devices (70- and 120-w). The median prostate volume reduction was 81.70% and 82.19% with 70- and 120-w ThuVEP, respectively. The incidence of complications was low and did not differ between groups treated with the different devices. Two patients (2.4%) (one per group) had a bladder neck contracture at the follow-up. ThuVEP is a safe and efficacious procedure for the treatment of symptomatic BPO. The incidence of complications was low with both devices. The 120-w thulium:YAG device enhances the effectiveness of ThuVEP with regard to the percentage of resected tissue and the enucleation/operation efficiency.</p>
</abstract>
<kwd-group><kwd>benign prostatic obstruction</kwd>
<kwd>laser</kwd>
<kwd>prostate</kwd>
<kwd>Revolix</kwd>
<kwd>Tm:YAG</kwd>
<kwd>ThuVEP</kwd>
<kwd>VapoEnucleation</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
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