Multicolor Upconversion Nanoparticles for Protein Conjugation
Identifieur interne : 000472 ( Main/Exploration ); précédent : 000471; suivant : 000473Multicolor Upconversion Nanoparticles for Protein Conjugation
Auteurs : Stefan Wilhelm [Allemagne] ; Thomas Hirsch [Allemagne] ; Wendy M. Patterson [Allemagne] ; Elisabeth Scheucher [Autriche] ; Torsten Mayr [Autriche] ; Otto S. Wolfbeis [Allemagne]Source :
- Theranostics [ 1838-7640 ] ; 2013.
Abstract
We describe the preparation of monodisperse, lanthanide-doped hexagonal-phase NaYF4 upconverting luminescent nanoparticles for protein conjugation. Their core was coated with a silica shell which then was modified with a poly(ethylene glycol) spacer and N-hydroxysuccinimide ester groups. The nanoparticles were characterized by transmission electron microscopy, Raman spectroscopy, X-ray diffraction, and dynamic light scattering. The N-hydroxysuccinimide ester functionalization renders them highly reactive towards amine nucleophiles (e.g., proteins). We show that such particles can be conjugated to proteins. The protein-reactive UCLNPs and their conjugates to streptavidin and bovine serum albumin display multicolor emissions upon 980-nm continuous wave laser excitation. Surface plasmon resonance studies were carried out to prove bioconjugation and to compare the affinity of the particles for proteins immobilized on a thin gold film.
Url:
DOI: 10.7150/thno.5113
PubMed: 23606910
PubMed Central: 3630524
Affiliations:
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University of Regensburg, Institute of Analytical Chemistry, Chemo- and Biosensors, 93040 Regensburg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>1. University of Regensburg, Institute of Analytical Chemistry, Chemo- and Biosensors, 93040 Regensburg</wicri:regionArea><wicri:noRegion>93040 Regensburg</wicri:noRegion><wicri:noRegion>93040 Regensburg</wicri:noRegion><wicri:noRegion>93040 Regensburg</wicri:noRegion></affiliation></author><author><name sortKey="Hirsch, Thomas" sort="Hirsch, Thomas" uniqKey="Hirsch T" first="Thomas" last="Hirsch">Thomas Hirsch</name><affiliation wicri:level="1"><nlm:aff id="A1">1. University of Regensburg, Institute of Analytical Chemistry, Chemo- and Biosensors, 93040 Regensburg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>1. University of Regensburg, Institute of Analytical Chemistry, Chemo- and Biosensors, 93040 Regensburg</wicri:regionArea><wicri:noRegion>93040 Regensburg</wicri:noRegion><wicri:noRegion>93040 Regensburg</wicri:noRegion><wicri:noRegion>93040 Regensburg</wicri:noRegion></affiliation></author><author><name sortKey="Patterson, Wendy M" sort="Patterson, Wendy M" uniqKey="Patterson W" first="Wendy M." last="Patterson">Wendy M. Patterson</name><affiliation wicri:level="1"><nlm:aff id="A1">1. University of Regensburg, Institute of Analytical Chemistry, Chemo- and Biosensors, 93040 Regensburg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>1. University of Regensburg, Institute of Analytical Chemistry, Chemo- and Biosensors, 93040 Regensburg</wicri:regionArea><wicri:noRegion>93040 Regensburg</wicri:noRegion><wicri:noRegion>93040 Regensburg</wicri:noRegion><wicri:noRegion>93040 Regensburg</wicri:noRegion></affiliation></author><author><name sortKey="Scheucher, Elisabeth" sort="Scheucher, Elisabeth" uniqKey="Scheucher E" first="Elisabeth" last="Scheucher">Elisabeth Scheucher</name><affiliation wicri:level="1"><nlm:aff id="A2">2. Graz University of Technology, Institute of Analytical Chemistry and Food Chemistry, 8010 Graz, Austria.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Autriche</country><wicri:regionArea>2. Graz University of Technology, Institute of Analytical Chemistry and Food Chemistry, 8010 Graz</wicri:regionArea><wicri:noRegion>8010 Graz</wicri:noRegion></affiliation></author><author><name sortKey="Mayr, Torsten" sort="Mayr, Torsten" uniqKey="Mayr T" first="Torsten" last="Mayr">Torsten Mayr</name><affiliation wicri:level="1"><nlm:aff id="A2">2. Graz University of Technology, Institute of Analytical Chemistry and Food Chemistry, 8010 Graz, Austria.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Autriche</country><wicri:regionArea>2. Graz University of Technology, Institute of Analytical Chemistry and Food Chemistry, 8010 Graz</wicri:regionArea><wicri:noRegion>8010 Graz</wicri:noRegion></affiliation></author><author><name sortKey="Wolfbeis, Otto S" sort="Wolfbeis, Otto S" uniqKey="Wolfbeis O" first="Otto S." last="Wolfbeis">Otto S. Wolfbeis</name><affiliation wicri:level="1"><nlm:aff id="A1">1. University of Regensburg, Institute of Analytical Chemistry, Chemo- and Biosensors, 93040 Regensburg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>1. University of Regensburg, Institute of Analytical Chemistry, Chemo- and Biosensors, 93040 Regensburg</wicri:regionArea><wicri:noRegion>93040 Regensburg</wicri:noRegion><wicri:noRegion>93040 Regensburg</wicri:noRegion><wicri:noRegion>93040 Regensburg</wicri:noRegion></affiliation></author></analytic><series><title level="j">Theranostics</title><idno type="eISSN">1838-7640</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>We describe the preparation of monodisperse, lanthanide-doped hexagonal-phase NaYF<sub>4</sub> upconverting luminescent nanoparticles for protein conjugation. Their core was coated with a silica shell which then was modified with a poly(ethylene glycol) spacer and N-hydroxysuccinimide ester groups. The nanoparticles were characterized by transmission electron microscopy, Raman spectroscopy, X-ray diffraction, and dynamic light scattering. The N-hydroxysuccinimide ester functionalization renders them highly reactive towards amine nucleophiles (e.g., proteins). We show that such particles can be conjugated to proteins. The protein-reactive UCLNPs and their conjugates to streptavidin and bovine serum albumin display multicolor emissions upon 980-nm continuous wave laser excitation. Surface plasmon resonance studies were carried out to prove bioconjugation and to compare the affinity of the particles for proteins immobilized on a thin gold film.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Lee, J H" uniqKey="Lee J">J-H Lee</name></author><author><name sortKey="Huh, Y M" uniqKey="Huh Y">Y-M Huh</name></author><author><name sortKey="Jun, Y" uniqKey="Jun Y">Y Jun</name></author><author><name sortKey="Seo, J" uniqKey="Seo J">J Seo</name></author><author><name sortKey="Jang, J" uniqKey="Jang J">J Jang</name></author><author><name sortKey="Song, H T" uniqKey="Song H">H-T Song</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Medintz, Il" uniqKey="Medintz I">IL Medintz</name></author><author><name sortKey="Uyeda, Ht" uniqKey="Uyeda H">HT Uyeda</name></author><author><name sortKey="Goldman, Er" uniqKey="Goldman E">ER Goldman</name></author><author><name sortKey="Mattoussi, H" uniqKey="Mattoussi H">H Mattoussi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Michalet, X" uniqKey="Michalet X">X Michalet</name></author><author><name sortKey="Pinaud, Ff" uniqKey="Pinaud F">FF Pinaud</name></author><author><name sortKey="Bentolila, La" uniqKey="Bentolila L">LA Bentolila</name></author><author><name sortKey="Tsay, Jm" uniqKey="Tsay J">JM Tsay</name></author><author><name sortKey="Doose, S" uniqKey="Doose S">S Doose</name></author><author><name sortKey="Li, Jj" uniqKey="Li J">JJ Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hilderbrand, Sa" uniqKey="Hilderbrand S">SA Hilderbrand</name></author><author><name sortKey="Shao, F" uniqKey="Shao F">F Shao</name></author><author><name sortKey="Salthouse, C" uniqKey="Salthouse C">C Salthouse</name></author><author><name sortKey="Mahmood, U" uniqKey="Mahmood U">U Mahmood</name></author><author><name sortKey="Weissleder, R" uniqKey="Weissleder R">R Weissleder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mader, Hs" uniqKey="Mader H">HS Mader</name></author><author><name sortKey="Kele, P" uniqKey="Kele P">P Kele</name></author><author><name sortKey="Saleh, Sm" uniqKey="Saleh S">SM Saleh</name></author><author><name sortKey="Wolfbeis, Os" uniqKey="Wolfbeis O">OS Wolfbeis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Agasti, Ss" uniqKey="Agasti S">SS Agasti</name></author><author><name sortKey="Rana, S" uniqKey="Rana S">S Rana</name></author><author><name sortKey="Park, M H" uniqKey="Park M">M-H Park</name></author><author><name sortKey="Kim, Ck" uniqKey="Kim C">CK Kim</name></author><author><name sortKey="You, C C" uniqKey="You C">C-C You</name></author><author><name sortKey="Rotello, Vm" uniqKey="Rotello V">VM Rotello</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Von Maltzahn, G" uniqKey="Von Maltzahn G">G von Maltzahn</name></author><author><name sortKey="Park, J H" uniqKey="Park J">J-H Park</name></author><author><name sortKey="Lin, Ky" uniqKey="Lin K">KY Lin</name></author><author><name sortKey="Singh, N" uniqKey="Singh N">N Singh</name></author><author><name sortKey="Schwoppe, C" uniqKey="Schwoppe C">C Schwöppe</name></author><author><name sortKey="Mesters, R" uniqKey="Mesters R">R Mesters</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zrazhevskiy, P" uniqKey="Zrazhevskiy P">P Zrazhevskiy</name></author><author><name sortKey="Sena, M" uniqKey="Sena M">M Sena</name></author><author><name sortKey="Gao, X" uniqKey="Gao X">X Gao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, H" uniqKey="Wang H">H Wang</name></author><author><name sortKey="Leeuwenburgh, Scg" uniqKey="Leeuwenburgh S">SCG Leeuwenburgh</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name></author><author><name sortKey="Jansen, Ja" uniqKey="Jansen J">JA Jansen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Davis, Me" uniqKey="Davis M">ME Davis</name></author><author><name sortKey="Zuckerman, Je" uniqKey="Zuckerman J">JE Zuckerman</name></author><author><name sortKey="Choi, Chj" uniqKey="Choi C">CHJ Choi</name></author><author><name sortKey="Seligson, D" uniqKey="Seligson D">D Seligson</name></author><author><name sortKey="Tolcher, A" uniqKey="Tolcher A">A Tolcher</name></author><author><name sortKey="Alabi, Ca" uniqKey="Alabi C">CA Alabi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ma, X" uniqKey="Ma X">X Ma</name></author><author><name sortKey="Zhao, Y" uniqKey="Zhao Y">Y Zhao</name></author><author><name sortKey="Liang, X J" uniqKey="Liang X">X-J Liang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yong, Kt" uniqKey="Yong K">KT Yong</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Roy, I" uniqKey="Roy I">I Roy</name></author><author><name sortKey="Rui, H" uniqKey="Rui H">H Rui</name></author><author><name sortKey="Swihart, Mt" uniqKey="Swihart M">MT Swihart</name></author><author><name sortKey="Law, Wc" uniqKey="Law W">WC Law</name></author><author><name sortKey="Kwak, Sk" uniqKey="Kwak S">SK Kwak</name></author><author><name sortKey="Ye, L" uniqKey="Ye L">L Ye</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J Liu</name></author><author><name sortKey="Mahajan, Sd" uniqKey="Mahajan S">SD Mahajan</name></author><author><name sortKey="Reynolds, Jl" uniqKey="Reynolds J">JL Reynolds</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Park, J" uniqKey="Park J">J Park</name></author><author><name sortKey="An, K" uniqKey="An K">K An</name></author><author><name sortKey="Hwang, Y" uniqKey="Hwang Y">Y Hwang</name></author><author><name sortKey="Park, J G" uniqKey="Park J">J-G Park</name></author><author><name sortKey="Noh, H J" uniqKey="Noh H">H-J Noh</name></author><author><name sortKey="Kim, J Y" uniqKey="Kim J">J-Y Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frey, Na" uniqKey="Frey N">NA Frey</name></author><author><name sortKey="Peng, S" uniqKey="Peng S">S Peng</name></author><author><name sortKey="Cheng, K" uniqKey="Cheng K">K Cheng</name></author><author><name sortKey="Sun, S" uniqKey="Sun S">S Sun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ye, X" uniqKey="Ye X">X Ye</name></author><author><name sortKey="Collins, Je" uniqKey="Collins J">JE Collins</name></author><author><name sortKey="Kang, Y" uniqKey="Kang Y">Y Kang</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J Chen</name></author><author><name sortKey="Chen, Dtn" uniqKey="Chen D">DTN Chen</name></author><author><name sortKey="Yodh, Ag" uniqKey="Yodh A">AG Yodh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Singamaneni, S" uniqKey="Singamaneni S">S Singamaneni</name></author><author><name sortKey="Bliznyuk, Vn" uniqKey="Bliznyuk V">VN Bliznyuk</name></author><author><name sortKey="Binek, C" uniqKey="Binek C">C Binek</name></author><author><name sortKey="Tsymbal, Ey" uniqKey="Tsymbal E">EY Tsymbal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shao, H" uniqKey="Shao H">H Shao</name></author><author><name sortKey="Min, C" uniqKey="Min C">C Min</name></author><author><name sortKey="Issadore, D" uniqKey="Issadore D">D Issadore</name></author><author><name sortKey="Liong, M" uniqKey="Liong M">M Liong</name></author><author><name sortKey="Yoon, Tj" uniqKey="Yoon T">TJ Yoon</name></author><author><name sortKey="Weissleder, R" uniqKey="Weissleder R">R Weissleder</name></author><author><name sortKey="Lee, H" uniqKey="Lee H">H Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gao, J" uniqKey="Gao J">J Gao</name></author><author><name sortKey="Gu, H" uniqKey="Gu H">H Gu</name></author><author><name sortKey="Xu, B" uniqKey="Xu B">B Xu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boisselier, E" uniqKey="Boisselier E">E Boisselier</name></author><author><name sortKey="Astruc, D" uniqKey="Astruc D">D Astruc</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alivisatos, Ap" uniqKey="Alivisatos A">AP Alivisatos</name></author><author><name sortKey="Gu, W" uniqKey="Gu W">W Gu</name></author><author><name sortKey="Larabell, C" uniqKey="Larabell C">C Larabell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, L" uniqKey="Liu L">L Liu</name></author><author><name sortKey="Yong, Kt" uniqKey="Yong K">KT Yong</name></author><author><name sortKey="Roy, I" uniqKey="Roy I">I Roy</name></author><author><name sortKey="Law, Wc" uniqKey="Law W">WC Law</name></author><author><name sortKey="Ye, L" uniqKey="Ye L">L Ye</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J Liu</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J Liu</name></author><author><name sortKey="Kumar, R" uniqKey="Kumar R">R Kumar</name></author><author><name sortKey="Zhang, X" uniqKey="Zhang X">X Zhang</name></author><author><name sortKey="Prasad, Pn" uniqKey="Prasad P">PN Prasad</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhuang, Z" uniqKey="Zhuang Z">Z Zhuang</name></author><author><name sortKey="Peng, Q" uniqKey="Peng Q">Q Peng</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zou, H" uniqKey="Zou H">H Zou</name></author><author><name sortKey="Wu, S" uniqKey="Wu S">S Wu</name></author><author><name sortKey="Shen, J" uniqKey="Shen J">J Shen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vennerberg, D" uniqKey="Vennerberg D">D Vennerberg</name></author><author><name sortKey="Lin, Z" uniqKey="Lin Z">Z Lin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Auzel, F" uniqKey="Auzel F">F Auzel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Menyuk, N" uniqKey="Menyuk N">N Menyuk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, S" uniqKey="Wu S">S Wu</name></author><author><name sortKey="Han, G" uniqKey="Han G">G Han</name></author><author><name sortKey="Milliron, Dj" uniqKey="Milliron D">DJ Milliron</name></author><author><name sortKey="Aloni, S" uniqKey="Aloni S">S Aloni</name></author><author><name sortKey="Altoe, V" uniqKey="Altoe V">V Altoe</name></author><author><name sortKey="Talapin, Dv" uniqKey="Talapin D">DV Talapin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Park, Yi" uniqKey="Park Y">YI Park</name></author><author><name sortKey="Kim, Jh" uniqKey="Kim J">JH Kim</name></author><author><name sortKey="Lee, Kt" uniqKey="Lee K">KT Lee</name></author><author><name sortKey="Jeon, K" uniqKey="Jeon K">K Jeon</name></author><author><name sortKey="Na, Hb" uniqKey="Na H">HB Na</name></author><author><name sortKey="Yu, Jh" uniqKey="Yu J">JH Yu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, F" uniqKey="Wang F">F Wang</name></author><author><name sortKey="Han, Y" uniqKey="Han Y">Y Han</name></author><author><name sortKey="Lim, Cs" uniqKey="Lim C">CS Lim</name></author><author><name sortKey="Lu, Y" uniqKey="Lu Y">Y Lu</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J Wang</name></author><author><name sortKey="Xu, J" uniqKey="Xu J">J Xu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Achatz, De" uniqKey="Achatz D">DE Achatz</name></author><author><name sortKey="Ali, R" uniqKey="Ali R">R Ali</name></author><author><name sortKey="Wolfbeis, Os" uniqKey="Wolfbeis O">OS Wolfbeis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, G" uniqKey="Chen G">G Chen</name></author><author><name sortKey="Shen, J" uniqKey="Shen J">J Shen</name></author><author><name sortKey="Ohulchanskyy, Ty" uniqKey="Ohulchanskyy T">TY Ohulchanskyy</name></author><author><name sortKey="Patel, Nj" uniqKey="Patel N">NJ Patel</name></author><author><name sortKey="Kutikov, A" uniqKey="Kutikov A">A Kutikov</name></author><author><name sortKey="Li, Z" uniqKey="Li Z">Z Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuningas, K" uniqKey="Kuningas K">K Kuningas</name></author><author><name sortKey="Ukonaho, T" uniqKey="Ukonaho T">T Ukonaho</name></author><author><name sortKey="P Kkil, H" uniqKey="P Kkil H">H Päkkilä</name></author><author><name sortKey="Rantanen, T" uniqKey="Rantanen T">T Rantanen</name></author><author><name sortKey="Rosenberg, J" uniqKey="Rosenberg J">J Rosenberg</name></author><author><name sortKey="Lovgren, T" uniqKey="Lovgren T">T Lövgren</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rantanen, T" uniqKey="Rantanen T">T Rantanen</name></author><author><name sortKey="J Rvenp, M L" uniqKey="J Rvenp M">M-L Järvenpää</name></author><author><name sortKey="Vuojola, J" uniqKey="Vuojola J">J Vuojola</name></author><author><name sortKey="Kuningas, K" uniqKey="Kuningas K">K Kuningas</name></author><author><name sortKey="Soukka, T" uniqKey="Soukka T">T Soukka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abel, Ka" uniqKey="Abel K">KA Abel</name></author><author><name sortKey="Boyer, J C" uniqKey="Boyer J">J-C Boyer</name></author><author><name sortKey="Veggel Fcjm, Van" uniqKey="Veggel Fcjm V">van Veggel FCJM</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, G" uniqKey="Chen G">G Chen</name></author><author><name sortKey="Ohulchanskyy, Ty" uniqKey="Ohulchanskyy T">TY Ohulchanskyy</name></author><author><name sortKey="Kumar, R" uniqKey="Kumar R">R Kumar</name></author><author><name sortKey=" Gren, H" uniqKey=" Gren H">H Ågren</name></author><author><name sortKey="Prasad, Pn" uniqKey="Prasad P">PN Prasad</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abdul Jalil, R" uniqKey="Abdul Jalil R">R Abdul Jalil</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnson, Njj" uniqKey="Johnson N">NJJ Johnson</name></author><author><name sortKey="Sangeetha, Nm" uniqKey="Sangeetha N">NM Sangeetha</name></author><author><name sortKey="Boyer, J C" uniqKey="Boyer J">J-C Boyer</name></author><author><name sortKey="Veggel Fcjm, Van" uniqKey="Veggel Fcjm V">van Veggel FCJM</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Z" uniqKey="Li Z">Z Li</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name></author><author><name sortKey="Shuter, B" uniqKey="Shuter B">B Shuter</name></author><author><name sortKey="Muhammad Idris, N" uniqKey="Muhammad Idris N">N Muhammad Idris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jana, Nr" uniqKey="Jana N">NR Jana</name></author><author><name sortKey="Earhart, C" uniqKey="Earhart C">C Earhart</name></author><author><name sortKey="Ying, Jy" uniqKey="Ying J">JY Ying</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Park, Jc" uniqKey="Park J">JC Park</name></author><author><name sortKey="Gilbert, Da" uniqKey="Gilbert D">DA Gilbert</name></author><author><name sortKey="Liu, K" uniqKey="Liu K">K Liu</name></author><author><name sortKey="Louie, Ay" uniqKey="Louie A">AY Louie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Salgueiri O Maceira, V" uniqKey="Salgueiri O Maceira V">V Salgueiriño-Maceira</name></author><author><name sortKey="Correa Duarte, Ma" uniqKey="Correa Duarte M">MA Correa-Duarte</name></author><author><name sortKey="Spasova, M" uniqKey="Spasova M">M Spasova</name></author><author><name sortKey="Liz Marzan, Lm" uniqKey="Liz Marzan L">LM Liz-Marzán</name></author><author><name sortKey="Farle, M" uniqKey="Farle M">M Farle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mader, Hs" uniqKey="Mader H">HS Mader</name></author><author><name sortKey="Link, M" uniqKey="Link M">M Link</name></author><author><name sortKey="Achatz, De" uniqKey="Achatz D">DE Achatz</name></author><author><name sortKey="Uhlmann, K" uniqKey="Uhlmann K">K Uhlmann</name></author><author><name sortKey="Li, X" uniqKey="Li X">X Li</name></author><author><name sortKey="Wolfbeis, Os" uniqKey="Wolfbeis O">OS Wolfbeis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ehlert, O" uniqKey="Ehlert O">O Ehlert</name></author><author><name sortKey="Thomann, R" uniqKey="Thomann R">R Thomann</name></author><author><name sortKey="Darbandi, M" uniqKey="Darbandi M">M Darbandi</name></author><author><name sortKey="Nann, T" uniqKey="Nann T">T Nann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sivakumar, S" uniqKey="Sivakumar S">S Sivakumar</name></author><author><name sortKey="Diamente, Pr" uniqKey="Diamente P">PR Diamente</name></author><author><name sortKey="Van Veggel, Fcjm" uniqKey="Van Veggel F">FCJM van Veggel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, F" uniqKey="Wang F">F Wang</name></author><author><name sortKey="Liu, X" uniqKey="Liu X">X Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Z" uniqKey="Li Z">Z Li</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name></author><author><name sortKey="Jiang, S" uniqKey="Jiang S">S Jiang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mirsky, Vm" uniqKey="Mirsky V">VM Mirsky</name></author><author><name sortKey="Riepl, M" uniqKey="Riepl M">M Riepl</name></author><author><name sortKey="Wolfbeis, Os" uniqKey="Wolfbeis O">OS Wolfbeis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haase, M" uniqKey="Haase M">M Haase</name></author><author><name sortKey="Sch Fer, H" uniqKey="Sch Fer H">H Schäfer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Qian, H S" uniqKey="Qian H">H-S Qian</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sedlmeier, A" uniqKey="Sedlmeier A">A Sedlmeier</name></author><author><name sortKey="Achatz, De" uniqKey="Achatz D">DE Achatz</name></author><author><name sortKey="Fischer, Lh" uniqKey="Fischer L">LH Fischer</name></author><author><name sortKey="Gorris, Hh" uniqKey="Gorris H">HH Gorris</name></author><author><name sortKey="Wolfbeis, Os" uniqKey="Wolfbeis O">OS Wolfbeis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Miller, Sa" uniqKey="Miller S">SA Miller</name></author><author><name sortKey="Rast, He" uniqKey="Rast H">HE Rast</name></author><author><name sortKey="Caspers, Hh" uniqKey="Caspers H">HH Caspers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, G" uniqKey="Chen G">G Chen</name></author><author><name sortKey="Ohulchanskyy, Ty" uniqKey="Ohulchanskyy T">TY Ohulchanskyy</name></author><author><name sortKey="Kachynski, A" uniqKey="Kachynski A">A Kachynski</name></author><author><name sortKey=" Gren, H" uniqKey=" Gren H">H Ågren</name></author><author><name sortKey="Prasad, Pn" uniqKey="Prasad P">PN Prasad</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suyver, Jf" uniqKey="Suyver J">JF Suyver</name></author><author><name sortKey="Grimm, J" uniqKey="Grimm J">J Grimm</name></author><author><name sortKey="Van Veen, Mk" uniqKey="Van Veen M">MK van Veen</name></author><author><name sortKey="Biner, D" uniqKey="Biner D">D Biner</name></author><author><name sortKey="Kr Mer, Kw" uniqKey="Kr Mer K">KW Krämer</name></author><author><name sortKey="Gudel, Hu" uniqKey="Gudel H">HU Güdel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, Gk" uniqKey="Liu G">GK Liu</name></author><author><name sortKey="Chen, Xy" uniqKey="Chen X">XY Chen</name></author><author><name sortKey="Zhuang, Hz" uniqKey="Zhuang H">HZ Zhuang</name></author><author><name sortKey="Li, S" uniqKey="Li S">S Li</name></author><author><name sortKey="Niedbala, Rs" uniqKey="Niedbala R">RS Niedbala</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tandon, P" uniqKey="Tandon P">P Tandon</name></author><author><name sortKey="Forster, G" uniqKey="Forster G">G Förster</name></author><author><name sortKey="Neubert, R" uniqKey="Neubert R">R Neubert</name></author><author><name sortKey="Wartewig, S" uniqKey="Wartewig S">S Wartewig</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mayo, Dw" uniqKey="Mayo D">DW Mayo</name></author><author><name sortKey="Foil, Fa" uniqKey="Foil F">FA Foil</name></author><author><name sortKey="Hannah, Rw" uniqKey="Hannah R">RW Hannah</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Breitsprecher, D" uniqKey="Breitsprecher D">D Breitsprecher</name></author><author><name sortKey="Jaiswal, R" uniqKey="Jaiswal R">R Jaiswal</name></author><author><name sortKey="Bombardier, Jp" uniqKey="Bombardier J">JP Bombardier</name></author><author><name sortKey="Gould, Cj" uniqKey="Gould C">CJ Gould</name></author><author><name sortKey="Gelles, J" uniqKey="Gelles J">J Gelles</name></author><author><name sortKey="Goode, Bl" uniqKey="Goode B">BL Goode</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sperling, Ra" uniqKey="Sperling R">RA Sperling</name></author><author><name sortKey="Parak, Wj" uniqKey="Parak W">WJ Parak</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schasfoort, Rbm" uniqKey="Schasfoort R">RBM Schasfoort</name></author><author><name sortKey="Tudos, Aj" uniqKey="Tudos A">AJ Tudos</name></author><author><name sortKey="Schasfoort, Rbm" uniqKey="Schasfoort R">RBM Schasfoort</name></author><author><name sortKey="Tudos, Aj" uniqKey="Tudos A">AJ Tudos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liebherr, Rb" uniqKey="Liebherr R">RB Liebherr</name></author><author><name sortKey="Soukka, T" uniqKey="Soukka T">T Soukka</name></author><author><name sortKey="Wolfbeis, Os" uniqKey="Wolfbeis O">OS Wolfbeis</name></author><author><name sortKey="Gorris, Hh" uniqKey="Gorris H">HH Gorris</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li><li>Autriche</li></country></list><tree><country name="Allemagne"><noRegion><name sortKey="Wilhelm, Stefan" sort="Wilhelm, Stefan" uniqKey="Wilhelm S" first="Stefan" last="Wilhelm">Stefan Wilhelm</name></noRegion><name sortKey="Hirsch, Thomas" sort="Hirsch, Thomas" uniqKey="Hirsch T" first="Thomas" last="Hirsch">Thomas Hirsch</name><name sortKey="Patterson, Wendy M" sort="Patterson, Wendy M" uniqKey="Patterson W" first="Wendy M." last="Patterson">Wendy M. Patterson</name><name sortKey="Wolfbeis, Otto S" sort="Wolfbeis, Otto S" uniqKey="Wolfbeis O" first="Otto S." last="Wolfbeis">Otto S. Wolfbeis</name></country><country name="Autriche"><noRegion><name sortKey="Scheucher, Elisabeth" sort="Scheucher, Elisabeth" uniqKey="Scheucher E" first="Elisabeth" last="Scheucher">Elisabeth Scheucher</name></noRegion><name sortKey="Mayr, Torsten" sort="Mayr, Torsten" uniqKey="Mayr T" first="Torsten" last="Mayr">Torsten Mayr</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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