In vivo near‐infrared fluorescence imaging of cancer with nanoparticle‐based probes
Identifieur interne : 000D25 ( Main/Exploration ); précédent : 000D24; suivant : 000D26In vivo near‐infrared fluorescence imaging of cancer with nanoparticle‐based probes
Auteurs : Xiaoxiao He [États-Unis, République populaire de Chine] ; Kemin Wang [République populaire de Chine] ; Zhen Cheng [États-Unis]Source :
- Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology [ 1939-5116 ] ; 2010-07.
Descripteurs français
- Wicri :
- topic : Droit d'auteur, Nanotechnologie.
English descriptors
- KwdEn :
- Alloyed, American chemical society, Anal chem, Apolar core, Aqueous solution, Biomolecules, Biotechnol, Calcium phosphate nanoparticles, Cancer detection, Chem, Chem mater, Chen, Coprecipitation method, Copyright, Cpnps, Deep tissues, Dye, Excitation, Folic acid, High sensitivity, Hydrothermal, Hydrothermal method, Imaging, Lett, Ligand, Lipoprotein, Luminescence, Magnetic resonance imaging, Mater, Molecular imaging, Multicolor, Nano, Nano lett, Nanobiotechnology, Nanocrystals, Nanomedicine, Nanoparticle, Nanoparticlebased nirf probes, Nanoparticles, Nanosci nanotechnol, Nanotechnology, Nayf4, Nirf, Nirf dyes, Nirf probes, Nirf silica nanoparticles, Noninvasive, Optical imaging, Phospholipid monolayer, Phys, Phys chem, Precursor, Probe, Proc natl acad, Quantum, Quantum dots, Rare earth ions, Receptor, Semiconductor, Silica, Silica nanoparticles, Synthetic routes, Thermal decomposition, Toxicity, Tumor vasculature, Ucns, Uorescence, Uorescence imaging, Uorescence imaging wires nanomedicine, Uorescence signal, Uorescence signals, Uorescent, Uorescent nanoparticles, Uorophores, Upconversion, Upconversion luminescence, Upconversion nanoparticles, Upconverting, Vivo, Vivo cancer, Vivo cancer imaging, Vivo imaging, Wang, Wires nanomed nanobiotechnol, Zhang.
- Teeft :
- Alloyed, American chemical society, Anal chem, Apolar core, Aqueous solution, Biomolecules, Biotechnol, Calcium phosphate nanoparticles, Cancer detection, Chem, Chem mater, Chen, Coprecipitation method, Copyright, Cpnps, Deep tissues, Dye, Excitation, Folic acid, High sensitivity, Hydrothermal, Hydrothermal method, Imaging, Lett, Ligand, Lipoprotein, Luminescence, Magnetic resonance imaging, Mater, Molecular imaging, Multicolor, Nano, Nano lett, Nanobiotechnology, Nanocrystals, Nanomedicine, Nanoparticle, Nanoparticlebased nirf probes, Nanoparticles, Nanosci nanotechnol, Nanotechnology, Nayf4, Nirf, Nirf dyes, Nirf probes, Nirf silica nanoparticles, Noninvasive, Optical imaging, Phospholipid monolayer, Phys, Phys chem, Precursor, Probe, Proc natl acad, Quantum, Quantum dots, Rare earth ions, Receptor, Semiconductor, Silica, Silica nanoparticles, Synthetic routes, Thermal decomposition, Toxicity, Tumor vasculature, Ucns, Uorescence, Uorescence imaging, Uorescence imaging wires nanomedicine, Uorescence signal, Uorescence signals, Uorescent, Uorescent nanoparticles, Uorophores, Upconversion, Upconversion luminescence, Upconversion nanoparticles, Upconverting, Vivo, Vivo cancer, Vivo cancer imaging, Vivo imaging, Wang, Wires nanomed nanobiotechnol, Zhang.
Abstract
The use of in vivo near‐infrared fluorescence (NIRF) imaging techniques for sensitive cancer early detection is highly desirable, because biological tissues show very low absorption and autofluorescence in the NIR spectrum window. Cancer NIRF molecular imaging relies greatly on stable, highly specific and sensitive molecular probes. Nanoparticle‐based NIRF probes have overcome some of the limitations of the conventional NIRF organic dyes, such as poor hydrophilicity and photostability, low quantum yield, insufficient stability in biological system, low detection sensitivity, etc. Therefore, a lot of efforts have been made to actively develop novel NIRF nanoparticles for in vivo cancer molecular imaging. The main focus of this article is to provide a brief overview of the synthesis, surface modification, and in vivo cancer imaging applications of nanoparticle‐based NIRF probes, including dye‐containing nanoparticles, NIRF quantum dots, and upconversion nanoparticles. WIREs Nanomed Nanobiotechnol 2010 2 349–366 For further resources related to this article, please visit the WIREs website
Url:
DOI: 10.1002/wnan.85
Affiliations:
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<front><div type="abstract" xml:lang="en">The use of in vivo near‐infrared fluorescence (NIRF) imaging techniques for sensitive cancer early detection is highly desirable, because biological tissues show very low absorption and autofluorescence in the NIR spectrum window. Cancer NIRF molecular imaging relies greatly on stable, highly specific and sensitive molecular probes. Nanoparticle‐based NIRF probes have overcome some of the limitations of the conventional NIRF organic dyes, such as poor hydrophilicity and photostability, low quantum yield, insufficient stability in biological system, low detection sensitivity, etc. Therefore, a lot of efforts have been made to actively develop novel NIRF nanoparticles for in vivo cancer molecular imaging. The main focus of this article is to provide a brief overview of the synthesis, surface modification, and in vivo cancer imaging applications of nanoparticle‐based NIRF probes, including dye‐containing nanoparticles, NIRF quantum dots, and upconversion nanoparticles. WIREs Nanomed Nanobiotechnol 2010 2 349–366 For further resources related to this article, please visit the WIREs website</div>
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