Comparative analysis of 11 different radioisotopes for palliative treatment of bone metastases by computational methods.
Identifieur interne : 000343 ( Main/Exploration ); précédent : 000342; suivant : 000344Comparative analysis of 11 different radioisotopes for palliative treatment of bone metastases by computational methods.
Auteurs : Francisco D C. Guerra Liberal [Portugal] ; Adriana Alexandre S. Tavares [Portugal] ; João Manuel R S. Tavares [Portugal]Source :
- Medical physics [ 0094-2405 ] ; 2014.
Descripteurs français
- KwdFr :
- ADN (), Algorithmes, Altération de l'ADN, Humains, Lutétium (usage thérapeutique), Métastase tumorale, Méthode de Monte-Carlo, Particules bêta (usage thérapeutique), Radio-isotopes (), Radio-isotopes (usage thérapeutique), Radio-isotopes du strontium (usage thérapeutique), Radiopharmaceutiques (usage thérapeutique), Radium (usage thérapeutique), Rhénium (usage thérapeutique), Réparation de l'ADN, Samarium (usage thérapeutique), Simulation numérique, Soins palliatifs (), Tumeurs osseuses (anatomopathologie), Tumeurs osseuses (radiothérapie).
- MESH :
- anatomopathologie : Tumeurs osseuses.
- radiothérapie : Tumeurs osseuses.
- usage thérapeutique : Lutétium, Particules bêta, Radio-isotopes, Radio-isotopes du strontium, Radiopharmaceutiques, Radium, Rhénium, Samarium.
- ADN, Algorithmes, Altération de l'ADN, Humains, Métastase tumorale, Méthode de Monte-Carlo, Radio-isotopes, Réparation de l'ADN, Simulation numérique, Soins palliatifs.
English descriptors
- KwdEn :
- Algorithms, Beta Particles (therapeutic use), Bone Neoplasms (pathology), Bone Neoplasms (radiotherapy), Computer Simulation, DNA (chemistry), DNA Damage, DNA Repair, Humans, Lutetium (therapeutic use), Monte Carlo Method, Neoplasm Metastasis, Palliative Care (methods), Radioisotopes (chemistry), Radioisotopes (therapeutic use), Radiopharmaceuticals (therapeutic use), Radium (therapeutic use), Rhenium (therapeutic use), Samarium (therapeutic use), Strontium Radioisotopes (therapeutic use).
- MESH :
- chemical , chemistry : DNA, Radioisotopes.
- methods : Palliative Care.
- pathology : Bone Neoplasms.
- radiotherapy : Bone Neoplasms.
- therapeutic use : Beta Particles, Lutetium, Radioisotopes, Radiopharmaceuticals, Radium, Rhenium, Samarium, Strontium Radioisotopes.
- Algorithms, Computer Simulation, DNA Damage, DNA Repair, Humans, Monte Carlo Method, Neoplasm Metastasis.
Abstract
Throughout the years, the palliative treatment of bone metastases using bone seeking radiotracers has been part of the therapeutic resources used in oncology, but the choice of which bone seeking agent to use is not consensual across sites and limited data are available comparing the characteristics of each radioisotope. Computational simulation is a simple and practical method to study and to compare a variety of radioisotopes for different medical applications, including the palliative treatment of bone metastases. This study aims to evaluate and compare 11 different radioisotopes currently in use or under research for the palliative treatment of bone metastases using computational methods.
DOI: 10.1118/1.4897240
PubMed: 25370676
Affiliations:
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Le document en format XML
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<term>Bone Neoplasms (radiotherapy)</term>
<term>Computer Simulation</term>
<term>DNA (chemistry)</term>
<term>DNA Damage</term>
<term>DNA Repair</term>
<term>Humans</term>
<term>Lutetium (therapeutic use)</term>
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<term>Neoplasm Metastasis</term>
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<term>Radioisotopes (therapeutic use)</term>
<term>Radiopharmaceuticals (therapeutic use)</term>
<term>Radium (therapeutic use)</term>
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<term>Radio-isotopes du strontium (usage thérapeutique)</term>
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<term>Radio-isotopes</term>
<term>Radio-isotopes du strontium</term>
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<term>Radium</term>
<term>Rhénium</term>
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<term>Computer Simulation</term>
<term>DNA Damage</term>
<term>DNA Repair</term>
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<front><div type="abstract" xml:lang="en">Throughout the years, the palliative treatment of bone metastases using bone seeking radiotracers has been part of the therapeutic resources used in oncology, but the choice of which bone seeking agent to use is not consensual across sites and limited data are available comparing the characteristics of each radioisotope. Computational simulation is a simple and practical method to study and to compare a variety of radioisotopes for different medical applications, including the palliative treatment of bone metastases. This study aims to evaluate and compare 11 different radioisotopes currently in use or under research for the palliative treatment of bone metastases using computational methods.</div>
</front>
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<name sortKey="Tavares, Joao Manuel R S" sort="Tavares, Joao Manuel R S" uniqKey="Tavares J" first="João Manuel R S" last="Tavares">João Manuel R S. Tavares</name>
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