Middle Ear Prosthesis with Bactericidal Efficacy-In Vitro Investigation.
Identifieur interne : 000548 ( Main/Exploration ); précédent : 000547; suivant : 000549Middle Ear Prosthesis with Bactericidal Efficacy-In Vitro Investigation.
Auteurs : Magdalena Zi Bka [Pologne] ; Michał Dziadek [Pologne] ; El Bieta Menaszek [Pologne] ; Rafał Banasiuk [Pologne] ; Aleksandra Kr Licka [Pologne]Source :
- Molecules (Basel, Switzerland) [ 1420-3049 ] ; 2017.
Descripteurs français
- KwdFr :
- Antibactériens (pharmacologie), Argent (composition chimique), Butadiènes (composition chimique), Fibroblastes (cytologie), Fibroblastes (effets des médicaments et des substances chimiques), Humains (MeSH), Infections dues aux prothèses (prévention et contrôle), Lignée cellulaire (MeSH), Nanoparticules métalliques (composition chimique), Polystyrènes (composition chimique), Prolifération cellulaire (effets des médicaments et des substances chimiques), Propriétés de surface (MeSH), Prothèse ossiculaire (MeSH), Pseudomonadaceae (effets des médicaments et des substances chimiques), Résines acryliques (composition chimique), Staphylococcus aureus (effets des médicaments et des substances chimiques), Survie cellulaire (effets des médicaments et des substances chimiques), Tests de sensibilité microbienne (méthodes).
- MESH :
- composition chimique : Argent, Butadiènes, Nanoparticules métalliques, Polystyrènes, Résines acryliques.
- cytologie : Fibroblastes.
- effets des médicaments et des substances chimiques : Fibroblastes, Prolifération cellulaire, Pseudomonadaceae, Staphylococcus aureus, Survie cellulaire.
- méthodes : Tests de sensibilité microbienne.
- pharmacologie : Antibactériens.
- prévention et contrôle : Infections dues aux prothèses.
- Humains, Lignée cellulaire, Propriétés de surface, Prothèse ossiculaire.
English descriptors
- KwdEn :
- Acrylic Resins (chemistry), Anti-Bacterial Agents (pharmacology), Butadienes (chemistry), Cell Line (MeSH), Cell Proliferation (drug effects), Cell Survival (drug effects), Fibroblasts (cytology), Fibroblasts (drug effects), Humans (MeSH), Metal Nanoparticles (chemistry), Microbial Sensitivity Tests (methods), Ossicular Prosthesis (MeSH), Polystyrenes (chemistry), Prosthesis-Related Infections (prevention & control), Pseudomonadaceae (drug effects), Silver (chemistry), Staphylococcus aureus (drug effects), Surface Properties (MeSH).
- MESH :
- chemical , chemistry : Acrylic Resins, Butadienes, Polystyrenes, Silver.
- chemical , pharmacology : Anti-Bacterial Agents.
- chemistry : Metal Nanoparticles.
- cytology : Fibroblasts.
- drug effects : Cell Proliferation, Cell Survival, Fibroblasts, Pseudomonadaceae, Staphylococcus aureus.
- methods : Microbial Sensitivity Tests.
- prevention & control : Prosthesis-Related Infections.
- Cell Line, Humans, Ossicular Prosthesis, Surface Properties.
Abstract
Materials used in ossicular replacement prostheses must possess appropriate biological properties, such as biocompatibility, stability, no cytotoxicity. Due to the risk of infection (otitis media and chronic otitis media), it is desirable to use an antibacterial agent for illness prevention during the ossicular reconstruction. The goal of this work was to observe biological properties of a new composite prosthesis made of ABS containing silver nanoparticles (AgNPs 45T). Samples for biological tests and then a prototype of middle ear prosthesis were prepared using injection moulding and extrusion techniques. In vitro experiments were carried out to assess bactericidal efficacy against Staphylococcus aureus and Pseudomona aeruginosa standard strains, cell proliferation, viability and cytotoxicity, using Hs680.Tr. fibroblast cells. Surface parameters of the samples were evaluated, including roughness and wettability. The silver ions were continually released from the polymer in aqueous solution. The silver ions release was measured as increasing with time and concentration of the silver nanoparticles in the polymer matrix. No cytotoxicity effect was observed, while bactericidal efficacy was noticed for silver nanoparticles. The roughness studies showed an increase in roughness for the samples with silver nanoparticles. All polymer and composite materials containing silver nanoparticles showed hydrophilic properties. The composites were found to release silver ions at a concentration level capable of rendering the antimicrobial efficacy even with the lowest concentration of silver nanoparticles in the material. Our results demonstrate that middle ear prosthesis made of polymer and silver nanoparticles may eliminate bacteria during inflammation in the middle ear.
DOI: 10.3390/molecules22101681
PubMed: 28994723
PubMed Central: PMC6151403
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Middle Ear Prosthesis with Bactericidal Efficacy-In Vitro Investigation.</title>
<author><name sortKey="Zi Bka, Magdalena" sort="Zi Bka, Magdalena" uniqKey="Zi Bka M" first="Magdalena" last="Zi Bka">Magdalena Zi Bka</name>
<affiliation wicri:level="1"><nlm:affiliation>AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Ceramics and Refractories, Krakow 30-059, Poland. ziabka@agh.edu.pl.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Ceramics and Refractories, Krakow 30-059</wicri:regionArea>
<wicri:noRegion>Krakow 30-059</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dziadek, Michal" sort="Dziadek, Michal" uniqKey="Dziadek M" first="Michał" last="Dziadek">Michał Dziadek</name>
<affiliation wicri:level="1"><nlm:affiliation>AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Glass Technology and Amorphous Coatings, Krakow 30-059, Poland. dziadek@agh.edu.pl.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Glass Technology and Amorphous Coatings, Krakow 30-059</wicri:regionArea>
<wicri:noRegion>Krakow 30-059</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Menaszek, El Bieta" sort="Menaszek, El Bieta" uniqKey="Menaszek E" first="El Bieta" last="Menaszek">El Bieta Menaszek</name>
<affiliation wicri:level="1"><nlm:affiliation>UJ-Jagiellonian University, Medical College, Faculty of Pharmacy, Department of Cytobiology, Krakow 30-001, Poland. elzbieta.menaszek@uj.edu.pl.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>UJ-Jagiellonian University, Medical College, Faculty of Pharmacy, Department of Cytobiology, Krakow 30-001</wicri:regionArea>
<wicri:noRegion>Krakow 30-001</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Banasiuk, Rafal" sort="Banasiuk, Rafal" uniqKey="Banasiuk R" first="Rafał" last="Banasiuk">Rafał Banasiuk</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Gdansk, Intercollegiate Faculty of Biotechnology UG-GUMed, Department of Biotechnology, Laboratory of Biologically Active Compounds, Gdansk 80-307, Poland. rafal.banasiuk@biotech.ug.edu.pl.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>University of Gdansk, Intercollegiate Faculty of Biotechnology UG-GUMed, Department of Biotechnology, Laboratory of Biologically Active Compounds, Gdansk 80-307</wicri:regionArea>
<wicri:noRegion>Gdansk 80-307</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kr Licka, Aleksandra" sort="Kr Licka, Aleksandra" uniqKey="Kr Licka A" first="Aleksandra" last="Kr Licka">Aleksandra Kr Licka</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Gdansk, Intercollegiate Faculty of Biotechnology UG-GUMed, Department of Biotechnology, Laboratory of Biologically Active Compounds, Gdansk 80-307, Poland. aleksandra.krolicka@biotech.ug.edu.pl.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>University of Gdansk, Intercollegiate Faculty of Biotechnology UG-GUMed, Department of Biotechnology, Laboratory of Biologically Active Compounds, Gdansk 80-307</wicri:regionArea>
<wicri:noRegion>Gdansk 80-307</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2017">2017</date>
<idno type="RBID">pubmed:28994723</idno>
<idno type="pmid">28994723</idno>
<idno type="doi">10.3390/molecules22101681</idno>
<idno type="pmc">PMC6151403</idno>
<idno type="wicri:Area/Main/Corpus">000496</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000496</idno>
<idno type="wicri:Area/Main/Curation">000496</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000496</idno>
<idno type="wicri:Area/Main/Exploration">000496</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Middle Ear Prosthesis with Bactericidal Efficacy-In Vitro Investigation.</title>
<author><name sortKey="Zi Bka, Magdalena" sort="Zi Bka, Magdalena" uniqKey="Zi Bka M" first="Magdalena" last="Zi Bka">Magdalena Zi Bka</name>
<affiliation wicri:level="1"><nlm:affiliation>AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Ceramics and Refractories, Krakow 30-059, Poland. ziabka@agh.edu.pl.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Ceramics and Refractories, Krakow 30-059</wicri:regionArea>
<wicri:noRegion>Krakow 30-059</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dziadek, Michal" sort="Dziadek, Michal" uniqKey="Dziadek M" first="Michał" last="Dziadek">Michał Dziadek</name>
<affiliation wicri:level="1"><nlm:affiliation>AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Glass Technology and Amorphous Coatings, Krakow 30-059, Poland. dziadek@agh.edu.pl.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Glass Technology and Amorphous Coatings, Krakow 30-059</wicri:regionArea>
<wicri:noRegion>Krakow 30-059</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Menaszek, El Bieta" sort="Menaszek, El Bieta" uniqKey="Menaszek E" first="El Bieta" last="Menaszek">El Bieta Menaszek</name>
<affiliation wicri:level="1"><nlm:affiliation>UJ-Jagiellonian University, Medical College, Faculty of Pharmacy, Department of Cytobiology, Krakow 30-001, Poland. elzbieta.menaszek@uj.edu.pl.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>UJ-Jagiellonian University, Medical College, Faculty of Pharmacy, Department of Cytobiology, Krakow 30-001</wicri:regionArea>
<wicri:noRegion>Krakow 30-001</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Banasiuk, Rafal" sort="Banasiuk, Rafal" uniqKey="Banasiuk R" first="Rafał" last="Banasiuk">Rafał Banasiuk</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Gdansk, Intercollegiate Faculty of Biotechnology UG-GUMed, Department of Biotechnology, Laboratory of Biologically Active Compounds, Gdansk 80-307, Poland. rafal.banasiuk@biotech.ug.edu.pl.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>University of Gdansk, Intercollegiate Faculty of Biotechnology UG-GUMed, Department of Biotechnology, Laboratory of Biologically Active Compounds, Gdansk 80-307</wicri:regionArea>
<wicri:noRegion>Gdansk 80-307</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kr Licka, Aleksandra" sort="Kr Licka, Aleksandra" uniqKey="Kr Licka A" first="Aleksandra" last="Kr Licka">Aleksandra Kr Licka</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Gdansk, Intercollegiate Faculty of Biotechnology UG-GUMed, Department of Biotechnology, Laboratory of Biologically Active Compounds, Gdansk 80-307, Poland. aleksandra.krolicka@biotech.ug.edu.pl.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>University of Gdansk, Intercollegiate Faculty of Biotechnology UG-GUMed, Department of Biotechnology, Laboratory of Biologically Active Compounds, Gdansk 80-307</wicri:regionArea>
<wicri:noRegion>Gdansk 80-307</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Molecules (Basel, Switzerland)</title>
<idno type="eISSN">1420-3049</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acrylic Resins (chemistry)</term>
<term>Anti-Bacterial Agents (pharmacology)</term>
<term>Butadienes (chemistry)</term>
<term>Cell Line (MeSH)</term>
<term>Cell Proliferation (drug effects)</term>
<term>Cell Survival (drug effects)</term>
<term>Fibroblasts (cytology)</term>
<term>Fibroblasts (drug effects)</term>
<term>Humans (MeSH)</term>
<term>Metal Nanoparticles (chemistry)</term>
<term>Microbial Sensitivity Tests (methods)</term>
<term>Ossicular Prosthesis (MeSH)</term>
<term>Polystyrenes (chemistry)</term>
<term>Prosthesis-Related Infections (prevention & control)</term>
<term>Pseudomonadaceae (drug effects)</term>
<term>Silver (chemistry)</term>
<term>Staphylococcus aureus (drug effects)</term>
<term>Surface Properties (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Antibactériens (pharmacologie)</term>
<term>Argent (composition chimique)</term>
<term>Butadiènes (composition chimique)</term>
<term>Fibroblastes (cytologie)</term>
<term>Fibroblastes (effets des médicaments et des substances chimiques)</term>
<term>Humains (MeSH)</term>
<term>Infections dues aux prothèses (prévention et contrôle)</term>
<term>Lignée cellulaire (MeSH)</term>
<term>Nanoparticules métalliques (composition chimique)</term>
<term>Polystyrènes (composition chimique)</term>
<term>Prolifération cellulaire (effets des médicaments et des substances chimiques)</term>
<term>Propriétés de surface (MeSH)</term>
<term>Prothèse ossiculaire (MeSH)</term>
<term>Pseudomonadaceae (effets des médicaments et des substances chimiques)</term>
<term>Résines acryliques (composition chimique)</term>
<term>Staphylococcus aureus (effets des médicaments et des substances chimiques)</term>
<term>Survie cellulaire (effets des médicaments et des substances chimiques)</term>
<term>Tests de sensibilité microbienne (méthodes)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Acrylic Resins</term>
<term>Butadienes</term>
<term>Polystyrenes</term>
<term>Silver</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Anti-Bacterial Agents</term>
</keywords>
<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Metal Nanoparticles</term>
</keywords>
<keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Argent</term>
<term>Butadiènes</term>
<term>Nanoparticules métalliques</term>
<term>Polystyrènes</term>
<term>Résines acryliques</term>
</keywords>
<keywords scheme="MESH" qualifier="cytologie" xml:lang="fr"><term>Fibroblastes</term>
</keywords>
<keywords scheme="MESH" qualifier="cytology" xml:lang="en"><term>Fibroblasts</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Cell Proliferation</term>
<term>Cell Survival</term>
<term>Fibroblasts</term>
<term>Pseudomonadaceae</term>
<term>Staphylococcus aureus</term>
</keywords>
<keywords scheme="MESH" qualifier="effets des médicaments et des substances chimiques" xml:lang="fr"><term>Fibroblastes</term>
<term>Prolifération cellulaire</term>
<term>Pseudomonadaceae</term>
<term>Staphylococcus aureus</term>
<term>Survie cellulaire</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Microbial Sensitivity Tests</term>
</keywords>
<keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Tests de sensibilité microbienne</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Antibactériens</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Prosthesis-Related Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr"><term>Infections dues aux prothèses</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Cell Line</term>
<term>Humans</term>
<term>Ossicular Prosthesis</term>
<term>Surface Properties</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Humains</term>
<term>Lignée cellulaire</term>
<term>Propriétés de surface</term>
<term>Prothèse ossiculaire</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Materials used in ossicular replacement prostheses must possess appropriate biological properties, such as biocompatibility, stability, no cytotoxicity. Due to the risk of infection (otitis media and chronic otitis media), it is desirable to use an antibacterial agent for illness prevention during the ossicular reconstruction. The goal of this work was to observe biological properties of a new composite prosthesis made of ABS containing silver nanoparticles (AgNPs 45T). Samples for biological tests and then a prototype of middle ear prosthesis were prepared using injection moulding and extrusion techniques. In vitro experiments were carried out to assess bactericidal efficacy against <i>Staphylococcus aureus</i>
and <i>Pseudomona aeruginosa</i>
standard strains, cell proliferation, viability and cytotoxicity, using Hs680.Tr. fibroblast cells. Surface parameters of the samples were evaluated, including roughness and wettability. The silver ions were continually released from the polymer in aqueous solution. The silver ions release was measured as increasing with time and concentration of the silver nanoparticles in the polymer matrix. No cytotoxicity effect was observed, while bactericidal efficacy was noticed for silver nanoparticles. The roughness studies showed an increase in roughness for the samples with silver nanoparticles. All polymer and composite materials containing silver nanoparticles showed hydrophilic properties. The composites were found to release silver ions at a concentration level capable of rendering the antimicrobial efficacy even with the lowest concentration of silver nanoparticles in the material. Our results demonstrate that middle ear prosthesis made of polymer and silver nanoparticles may eliminate bacteria during inflammation in the middle ear.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28994723</PMID>
<DateCompleted><Year>2019</Year>
<Month>03</Month>
<Day>07</Day>
</DateCompleted>
<DateRevised><Year>2019</Year>
<Month>03</Month>
<Day>07</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1420-3049</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>22</Volume>
<Issue>10</Issue>
<PubDate><Year>2017</Year>
<Month>Oct</Month>
<Day>10</Day>
</PubDate>
</JournalIssue>
<Title>Molecules (Basel, Switzerland)</Title>
<ISOAbbreviation>Molecules</ISOAbbreviation>
</Journal>
<ArticleTitle>Middle Ear Prosthesis with Bactericidal Efficacy-In Vitro Investigation.</ArticleTitle>
<ELocationID EIdType="pii" ValidYN="Y">E1681</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.3390/molecules22101681</ELocationID>
<Abstract><AbstractText>Materials used in ossicular replacement prostheses must possess appropriate biological properties, such as biocompatibility, stability, no cytotoxicity. Due to the risk of infection (otitis media and chronic otitis media), it is desirable to use an antibacterial agent for illness prevention during the ossicular reconstruction. The goal of this work was to observe biological properties of a new composite prosthesis made of ABS containing silver nanoparticles (AgNPs 45T). Samples for biological tests and then a prototype of middle ear prosthesis were prepared using injection moulding and extrusion techniques. In vitro experiments were carried out to assess bactericidal efficacy against <i>Staphylococcus aureus</i>
and <i>Pseudomona aeruginosa</i>
standard strains, cell proliferation, viability and cytotoxicity, using Hs680.Tr. fibroblast cells. Surface parameters of the samples were evaluated, including roughness and wettability. The silver ions were continually released from the polymer in aqueous solution. The silver ions release was measured as increasing with time and concentration of the silver nanoparticles in the polymer matrix. No cytotoxicity effect was observed, while bactericidal efficacy was noticed for silver nanoparticles. The roughness studies showed an increase in roughness for the samples with silver nanoparticles. All polymer and composite materials containing silver nanoparticles showed hydrophilic properties. The composites were found to release silver ions at a concentration level capable of rendering the antimicrobial efficacy even with the lowest concentration of silver nanoparticles in the material. Our results demonstrate that middle ear prosthesis made of polymer and silver nanoparticles may eliminate bacteria during inflammation in the middle ear.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ziąbka</LastName>
<ForeName>Magdalena</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Ceramics and Refractories, Krakow 30-059, Poland. ziabka@agh.edu.pl.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Dziadek</LastName>
<ForeName>Michał</ForeName>
<Initials>M</Initials>
<Identifier Source="ORCID">0000-0001-5661-5467</Identifier>
<AffiliationInfo><Affiliation>AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Glass Technology and Amorphous Coatings, Krakow 30-059, Poland. dziadek@agh.edu.pl.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Menaszek</LastName>
<ForeName>Elżbieta</ForeName>
<Initials>E</Initials>
<Identifier Source="ORCID">0000-0002-0602-3583</Identifier>
<AffiliationInfo><Affiliation>UJ-Jagiellonian University, Medical College, Faculty of Pharmacy, Department of Cytobiology, Krakow 30-001, Poland. elzbieta.menaszek@uj.edu.pl.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Banasiuk</LastName>
<ForeName>Rafał</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>University of Gdansk, Intercollegiate Faculty of Biotechnology UG-GUMed, Department of Biotechnology, Laboratory of Biologically Active Compounds, Gdansk 80-307, Poland. rafal.banasiuk@biotech.ug.edu.pl.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Królicka</LastName>
<ForeName>Aleksandra</ForeName>
<Initials>A</Initials>
<Identifier Source="ORCID">0000-0001-5231-283X</Identifier>
<AffiliationInfo><Affiliation>University of Gdansk, Intercollegiate Faculty of Biotechnology UG-GUMed, Department of Biotechnology, Laboratory of Biologically Active Compounds, Gdansk 80-307, Poland. aleksandra.krolicka@biotech.ug.edu.pl.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2017</Year>
<Month>10</Month>
<Day>10</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Switzerland</Country>
<MedlineTA>Molecules</MedlineTA>
<NlmUniqueID>100964009</NlmUniqueID>
<ISSNLinking>1420-3049</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000180">Acrylic Resins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000900">Anti-Bacterial Agents</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D002070">Butadienes</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D011137">Polystyrenes</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>3M4G523W1G</RegistryNumber>
<NameOfSubstance UI="D012834">Silver</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>9003-56-9</RegistryNumber>
<NameOfSubstance UI="C024636">ABS resin</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000180" MajorTopicYN="N">Acrylic Resins</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000900" MajorTopicYN="N">Anti-Bacterial Agents</DescriptorName>
<QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002070" MajorTopicYN="N">Butadienes</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002460" MajorTopicYN="N">Cell Line</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D049109" MajorTopicYN="N">Cell Proliferation</DescriptorName>
<QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002470" MajorTopicYN="N">Cell Survival</DescriptorName>
<QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005347" MajorTopicYN="N">Fibroblasts</DescriptorName>
<QualifierName UI="Q000166" MajorTopicYN="N">cytology</QualifierName>
<QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D053768" MajorTopicYN="N">Metal Nanoparticles</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008826" MajorTopicYN="N">Microbial Sensitivity Tests</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009998" MajorTopicYN="Y">Ossicular Prosthesis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011137" MajorTopicYN="N">Polystyrenes</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016459" MajorTopicYN="N">Prosthesis-Related Infections</DescriptorName>
<QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011548" MajorTopicYN="N">Pseudomonadaceae</DescriptorName>
<QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012834" MajorTopicYN="N">Silver</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013211" MajorTopicYN="N">Staphylococcus aureus</DescriptorName>
<QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013499" MajorTopicYN="N">Surface Properties</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">bactericidal efficacy</Keyword>
<Keyword MajorTopicYN="N">cytotoxicity</Keyword>
<Keyword MajorTopicYN="N">middle ear prosthesis</Keyword>
<Keyword MajorTopicYN="N">ossicular reconstruction</Keyword>
</KeywordList>
<CoiStatement>The authors declare no conflict of interest.</CoiStatement>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year>
<Month>09</Month>
<Day>19</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2017</Year>
<Month>10</Month>
<Day>05</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2017</Year>
<Month>10</Month>
<Day>06</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2017</Year>
<Month>10</Month>
<Day>11</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2017</Year>
<Month>10</Month>
<Day>11</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2019</Year>
<Month>3</Month>
<Day>8</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>epublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">28994723</ArticleId>
<ArticleId IdType="pii">molecules22101681</ArticleId>
<ArticleId IdType="doi">10.3390/molecules22101681</ArticleId>
<ArticleId IdType="pmc">PMC6151403</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>J Biomed Mater Res. 2000 Feb;49(2):155-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10571901</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Eur Cell Mater. 2002 Sep 30;4:1-17</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14562250</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 2008 Jul 1;181(1):586-92</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18566425</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Laryngorhinootologie. 1996 Jun;75(6):335-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8766379</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biomater Appl. 2015 Jul;30(1):17-29</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25659947</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nano Today. 2014 Aug 1;9(4):478-498</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25267927</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mater Sci Eng C Mater Biol Appl. 2016 Jul 1;64:229-235</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27127048</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Int J Nanomedicine. 2016 Jan 19;11:315-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26855570</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2014 Jul 21;9(7):e102108</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25048192</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nanotechnology. 2005 Oct;16(10):2346-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20818017</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Res Pharm Sci. 2014 Nov-Dec;9(6):385-406</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26339255</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Dent Mater J. 2009 Jul;28(4):461-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19721284</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Int J Mol Sci. 2015 Jan 19;16(1):2099-116</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25607734</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Antimicrob Chemother. 2004 Dec;54(6):1019-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15537697</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Otolaryngol Allied Sci. 2000 Aug;25(4):287-92</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10971535</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biomaterials. 2005 May;26(14):2081-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15576182</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Chem Rev. 2013 Jul 10;113(7):4708-54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23488929</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Langmuir. 2008 Mar 4;24(5):2051-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18225933</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Med Oral Patol Oral Cir Bucal. 2015 Jan 01;20(1):e88-93</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25129252</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Ear Nose Throat J. 2005 Mar;84(3):142-4, 147-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15871581</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Acta Otorhinolaryngol Ital. 2007 Feb;27(1):45-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17601212</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Agric Food Chem. 2006 Aug 9;54(16):5814-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16881682</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Pologne</li>
</country>
</list>
<tree><country name="Pologne"><noRegion><name sortKey="Zi Bka, Magdalena" sort="Zi Bka, Magdalena" uniqKey="Zi Bka M" first="Magdalena" last="Zi Bka">Magdalena Zi Bka</name>
</noRegion>
<name sortKey="Banasiuk, Rafal" sort="Banasiuk, Rafal" uniqKey="Banasiuk R" first="Rafał" last="Banasiuk">Rafał Banasiuk</name>
<name sortKey="Dziadek, Michal" sort="Dziadek, Michal" uniqKey="Dziadek M" first="Michał" last="Dziadek">Michał Dziadek</name>
<name sortKey="Kr Licka, Aleksandra" sort="Kr Licka, Aleksandra" uniqKey="Kr Licka A" first="Aleksandra" last="Kr Licka">Aleksandra Kr Licka</name>
<name sortKey="Menaszek, El Bieta" sort="Menaszek, El Bieta" uniqKey="Menaszek E" first="El Bieta" last="Menaszek">El Bieta Menaszek</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Terre/explor/SilverBacteriV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000548 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000548 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Terre |area= SilverBacteriV1 |flux= Main |étape= Exploration |type= RBID |clé= pubmed:28994723 |texte= Middle Ear Prosthesis with Bactericidal Efficacy-In Vitro Investigation. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28994723" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a SilverBacteriV1
![]() | This area was generated with Dilib version V0.6.38. | ![]() |