The eefABC Multidrug Efflux Pump Operon Is Repressed by H-NS in Enterobacter aerogenes
Identifieur interne : 001374 ( Main/Exploration ); précédent : 001373; suivant : 001375The eefABC Multidrug Efflux Pump Operon Is Repressed by H-NS in Enterobacter aerogenes
Auteurs : Muriel Masi ; Jean-Marie Pagès ; Claude Villard ; Elizabeth PradelSource :
- Journal of Bacteriology [ 0021-9193 ] ; 2005.
Abstract
The
Url:
DOI: 10.1128/JB.187.11.3894-3897.2005
PubMed: 15901719
PubMed Central: 1112065
Affiliations:
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Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The <italic>eefABC</italic>
Multidrug Efflux Pump Operon Is Repressed by H-NS in <italic>Enterobacter aerogenes</italic>
</title>
<author><name sortKey="Masi, Muriel" sort="Masi, Muriel" uniqKey="Masi M" first="Muriel" last="Masi">Muriel Masi</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
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<author><name sortKey="Pages, Jean Marie" sort="Pages, Jean Marie" uniqKey="Pages J" first="Jean-Marie" last="Pagès">Jean-Marie Pagès</name>
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<author><name sortKey="Villard, Claude" sort="Villard, Claude" uniqKey="Villard C" first="Claude" last="Villard">Claude Villard</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pradel, Elizabeth" sort="Pradel, Elizabeth" uniqKey="Pradel E" first="Elizabeth" last="Pradel">Elizabeth Pradel</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The <italic>eefABC</italic>
Multidrug Efflux Pump Operon Is Repressed by H-NS in <italic>Enterobacter aerogenes</italic>
</title>
<author><name sortKey="Masi, Muriel" sort="Masi, Muriel" uniqKey="Masi M" first="Muriel" last="Masi">Muriel Masi</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pages, Jean Marie" sort="Pages, Jean Marie" uniqKey="Pages J" first="Jean-Marie" last="Pagès">Jean-Marie Pagès</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Villard, Claude" sort="Villard, Claude" uniqKey="Villard C" first="Claude" last="Villard">Claude Villard</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pradel, Elizabeth" sort="Pradel, Elizabeth" uniqKey="Pradel E" first="Elizabeth" last="Pradel">Elizabeth Pradel</name>
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<series><title level="j">Journal of Bacteriology</title>
<idno type="ISSN">0021-9193</idno>
<idno type="eISSN">1098-5530</idno>
<imprint><date when="2005">2005</date>
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<front><div type="abstract" xml:lang="en"><p>The <italic>Enterobacter aerogenes eefABC</italic>
locus, which encodes a tripartite efflux pump, was cloned by complementation of an <italic>Escherichia coli tolC</italic>
mutant. <italic>E. aerogenes</italic>
Δ<italic>acrA</italic>
expressing EefABC became less susceptible to a wide range of antibiotics. Data from <italic>eef</italic>
::<italic>lacZ</italic>
fusions showed that <italic>eefABC</italic>
was not transcribed in the various laboratory conditions tested. However, increased transcription from P<italic>eef</italic>
was observed in an <italic>E. coli hns</italic>
mutant. In addition, EefA was detected in <italic>E. aerogenes</italic>
expressing a dominant negative <italic>E. coli hns</italic>
allele.</p>
</div>
</front>
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<affiliations><list></list>
<tree><noCountry><name sortKey="Masi, Muriel" sort="Masi, Muriel" uniqKey="Masi M" first="Muriel" last="Masi">Muriel Masi</name>
<name sortKey="Pages, Jean Marie" sort="Pages, Jean Marie" uniqKey="Pages J" first="Jean-Marie" last="Pagès">Jean-Marie Pagès</name>
<name sortKey="Pradel, Elizabeth" sort="Pradel, Elizabeth" uniqKey="Pradel E" first="Elizabeth" last="Pradel">Elizabeth Pradel</name>
<name sortKey="Villard, Claude" sort="Villard, Claude" uniqKey="Villard C" first="Claude" last="Villard">Claude Villard</name>
</noCountry>
</tree>
</affiliations>
</record>
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