Cross-Reactivity of Neutralizing Antibodies among Malignant Catarrhal Fever Viruses
Identifieur interne : 000028 ( Pmc/Curation ); précédent : 000027; suivant : 000029Cross-Reactivity of Neutralizing Antibodies among Malignant Catarrhal Fever Viruses
Auteurs : Naomi S. Taus [États-Unis] ; Cristina W. Cunha [États-Unis] ; Jana Marquard [États-Unis] ; Donal O Oole [États-Unis] ; Hong Li [États-Unis]Source :
- PLoS ONE [ 1932-6203 ] ; 2015.
Abstract
Some members of the gamma herpesvirus genus
Url:
DOI: 10.1371/journal.pone.0145073
PubMed: 26658281
PubMed Central: 4681746
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Taus</name><affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, Washington, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, Washington</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Cunha, Cristina W" sort="Cunha, Cristina W" uniqKey="Cunha C" first="Cristina W." last="Cunha">Cristina W. Cunha</name><affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Marquard, Jana" sort="Marquard, Jana" uniqKey="Marquard J" first="Jana" last="Marquard">Jana Marquard</name><affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington</wicri:regionArea></affiliation></author><author><name sortKey="O Oole, Donal" sort="O Oole, Donal" uniqKey="O Oole D" first="Donal" last="O Oole">Donal O Oole</name><affiliation wicri:level="1"><nlm:aff id="aff003"><addr-line>Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, Wyoming, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, Wyoming</wicri:regionArea></affiliation></author><author><name sortKey="Li, Hong" sort="Li, Hong" uniqKey="Li H" first="Hong" last="Li">Hong Li</name><affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, Washington, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, Washington</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26658281</idno><idno type="pmc">4681746</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681746</idno><idno type="RBID">PMC:4681746</idno><idno type="doi">10.1371/journal.pone.0145073</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000028</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000028</idno><idno type="wicri:Area/Pmc/Curation">000028</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000028</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Cross-Reactivity of Neutralizing Antibodies among Malignant Catarrhal Fever Viruses</title><author><name sortKey="Taus, Naomi S" sort="Taus, Naomi S" uniqKey="Taus N" first="Naomi S." last="Taus">Naomi S. Taus</name><affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, Washington, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, Washington</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Cunha, Cristina W" sort="Cunha, Cristina W" uniqKey="Cunha C" first="Cristina W." last="Cunha">Cristina W. Cunha</name><affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington</wicri:regionArea></affiliation></author><author><name sortKey="Marquard, Jana" sort="Marquard, Jana" uniqKey="Marquard J" first="Jana" last="Marquard">Jana Marquard</name><affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington</wicri:regionArea></affiliation></author><author><name sortKey="O Oole, Donal" sort="O Oole, Donal" uniqKey="O Oole D" first="Donal" last="O Oole">Donal O Oole</name><affiliation wicri:level="1"><nlm:aff id="aff003"><addr-line>Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, Wyoming, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, Wyoming</wicri:regionArea></affiliation></author><author><name sortKey="Li, Hong" sort="Li, Hong" uniqKey="Li H" first="Hong" last="Li">Hong Li</name><affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, Washington, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, Washington</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington</wicri:regionArea></affiliation></author></analytic><series><title level="j">PLoS ONE</title><idno type="eISSN">1932-6203</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Some members of the gamma herpesvirus genus <italic>Macavirus</italic> are maintained in nature as subclinical infections in well-adapted ungulate hosts. Transmission of these viruses to poorly adapted hosts, such as American bison and cattle, can result in the frequently fatal disease malignant catarrhal fever (MCF). Based on phylogenetic analysis, the MCF viruses (MCFV) cluster into two subgroups corresponding to the reservoir hosts’ subfamilies: Alcelaphinae/Hippotraginae and Caprinae. Antibody cross-reactivity among MCFVs has been demonstrated using techniques such as enzyme linked immunosorbent and immunofluorescence assays. However, minimal information is available as to whether virus neutralizing antibodies generated against one MCFV cross react with other members of the genus. This study tested the neutralizing activity of serum and plasma from select MCFV-infected reservoir hosts against alcelaphine herpesvirus 1 (AlHV-1) and ovine herpesvirus 2 (OvHV-2). Neutralizing antibody activity against AlHV-1 was detected in samples from infected hosts in the Alcelaphinae and Hippotraginae subfamilies, but not from hosts in the Caprinae subfamily. OvHV-2 neutralizing activity was demonstrated in samples from goats (Caprinae) but not from wildebeest (Alcelaphinae). These results show that neutralizing antibody cross reactivity is present to MCFVs within a virus subgroup but not between subgroups. This information is important for diagnosing infection with MCFVs and in the development of vaccines against MCF.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Davison, Aj" uniqKey="Davison A">AJ Davison</name></author><author><name sortKey="Eberle, R" uniqKey="Eberle R">R Eberle</name></author><author><name sortKey="Ehlers, B" uniqKey="Ehlers B">B Ehlers</name></author><author><name sortKey="Haywood, Gc" uniqKey="Haywood G">GC Haywood</name></author><author><name sortKey="Mcgeoch, Dt" uniqKey="Mcgeoch D">DT McGeoch</name></author><author><name sortKey="Minson, Ac" uniqKey="Minson A">AC Minson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, H" uniqKey="Li H">H Li</name></author><author><name sortKey="Cunha, Cw" uniqKey="Cunha C">CW Cunha</name></author><author><name sortKey="Taus, Ns" uniqKey="Taus N">NS Taus</name></author><author><name sortKey="Knowles, Dp" uniqKey="Knowles D">DP 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<front><journal-meta><journal-id journal-id-type="nlm-ta">PLoS One</journal-id><journal-id journal-id-type="iso-abbrev">PLoS ONE</journal-id><journal-id journal-id-type="publisher-id">plos</journal-id><journal-id journal-id-type="pmc">plosone</journal-id><journal-title-group><journal-title>PLoS ONE</journal-title></journal-title-group><issn pub-type="epub">1932-6203</issn><publisher><publisher-name>Public Library of Science</publisher-name><publisher-loc>San Francisco, CA USA</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26658281</article-id><article-id pub-id-type="pmc">4681746</article-id><article-id pub-id-type="doi">10.1371/journal.pone.0145073</article-id><article-id pub-id-type="publisher-id">PONE-D-15-37321</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Cross-Reactivity of Neutralizing Antibodies among Malignant Catarrhal Fever Viruses</article-title><alt-title alt-title-type="running-head">MCFVs and Neutralizing Antibodies</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Taus</surname><given-names>Naomi S.</given-names></name><xref ref-type="aff" rid="aff001"><sup>1</sup></xref><xref ref-type="aff" rid="aff002"><sup>2</sup></xref><xref rid="cor001" ref-type="corresp">*</xref></contrib><contrib contrib-type="author"><name><surname>Cunha</surname><given-names>Cristina W.</given-names></name><xref ref-type="aff" rid="aff002"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Marquard</surname><given-names>Jana</given-names></name><xref ref-type="aff" rid="aff002"><sup>2</sup></xref><xref ref-type="author-notes" rid="currentaff001"><sup>¤</sup></xref></contrib><contrib contrib-type="author"><name><surname>O’Toole</surname><given-names>Donal</given-names></name><xref ref-type="aff" rid="aff003"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Li</surname><given-names>Hong</given-names></name><xref ref-type="aff" rid="aff001"><sup>1</sup></xref><xref ref-type="aff" rid="aff002"><sup>2</sup></xref></contrib></contrib-group><aff id="aff001"><label>1</label><addr-line>Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, Washington, United States of America</addr-line></aff><aff id="aff002"><label>2</label><addr-line>Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, United States of America</addr-line></aff><aff id="aff003"><label>3</label><addr-line>Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, Wyoming, United States of America</addr-line></aff><contrib-group><contrib contrib-type="editor"><name><surname>Devlin</surname><given-names>Joanne M</given-names></name><role>Editor</role><xref ref-type="aff" rid="edit1"></xref></contrib></contrib-group><aff id="edit1"><addr-line>The University of Melbourne, AUSTRALIA</addr-line></aff><author-notes><fn fn-type="conflict" id="coi001"><p><bold>Competing Interests: </bold>The authors have declared that no competing interests exist.</p></fn><fn fn-type="con" id="contrib001"><p>Conceived and designed the experiments: NST CWC HL. Performed the experiments: CWC JM. Analyzed the data: NST CWC JM DO HL. Wrote the paper: NST CWC JM HL.</p></fn><fn fn-type="current-aff" id="currentaff001"><label>¤</label><p>Current address: 3163 Prospector Drive, Casper, Wyoming 82604, United States of America</p></fn><corresp id="cor001">* E-mail: <email>tausns@vetmed.wsu.edu</email></corresp></author-notes><pub-date pub-type="epub"><day>14</day><month>12</month><year>2015</year></pub-date><pub-date pub-type="collection"><year>2015</year></pub-date><volume>10</volume><issue>12</issue><elocation-id>e0145073</elocation-id><history><date date-type="received"><day>24</day><month>8</month><year>2015</year></date><date date-type="accepted"><day>29</day><month>11</month><year>2015</year></date></history><permissions><license xlink:href="https://creativecommons.org/publicdomain/zero/1.0/"><license-p>This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/publicdomain/zero/1.0/">Creative Commons CC0</ext-link> public domain dedication</license-p></license></permissions><self-uri content-type="pdf" xlink:type="simple" xlink:href="pone.0145073.pdf"></self-uri><abstract><p>Some members of the gamma herpesvirus genus <italic>Macavirus</italic> are maintained in nature as subclinical infections in well-adapted ungulate hosts. Transmission of these viruses to poorly adapted hosts, such as American bison and cattle, can result in the frequently fatal disease malignant catarrhal fever (MCF). Based on phylogenetic analysis, the MCF viruses (MCFV) cluster into two subgroups corresponding to the reservoir hosts’ subfamilies: Alcelaphinae/Hippotraginae and Caprinae. Antibody cross-reactivity among MCFVs has been demonstrated using techniques such as enzyme linked immunosorbent and immunofluorescence assays. However, minimal information is available as to whether virus neutralizing antibodies generated against one MCFV cross react with other members of the genus. This study tested the neutralizing activity of serum and plasma from select MCFV-infected reservoir hosts against alcelaphine herpesvirus 1 (AlHV-1) and ovine herpesvirus 2 (OvHV-2). Neutralizing antibody activity against AlHV-1 was detected in samples from infected hosts in the Alcelaphinae and Hippotraginae subfamilies, but not from hosts in the Caprinae subfamily. OvHV-2 neutralizing activity was demonstrated in samples from goats (Caprinae) but not from wildebeest (Alcelaphinae). These results show that neutralizing antibody cross reactivity is present to MCFVs within a virus subgroup but not between subgroups. This information is important for diagnosing infection with MCFVs and in the development of vaccines against MCF.</p></abstract><funding-group><funding-statement>This work was funded by the United States Department of Agriculture, Agricultural Research Service (CWU 5348-32000-032-00D). The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.</funding-statement></funding-group><counts><fig-count count="2"></fig-count><table-count count="1"></table-count><page-count count="9"></page-count></counts><custom-meta-group><custom-meta id="data-availability"><meta-name>Data Availability</meta-name><meta-value>All relevant data are within the paper and its Supporting Information files.</meta-value></custom-meta></custom-meta-group></article-meta><notes><title>Data Availability</title><p>All relevant data are within the paper and its Supporting Information files.</p></notes></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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|wiki= Wicri/Terre
|area= CobaltMaghrebV1
|flux= Pmc
|étape= Curation
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|clé= PMC:4681746
|texte= Cross-Reactivity of Neutralizing Antibodies among Malignant Catarrhal Fever Viruses
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