‘Bio-nano interactions: new tools, insights and impacts’: summary of the Royal Society discussion meeting
Identifieur interne : 000487 ( Pmc/Corpus ); précédent : 000486; suivant : 000488‘Bio-nano interactions: new tools, insights and impacts’: summary of the Royal Society discussion meeting
Auteurs : Iseult Lynch ; Ilise L. Feitshans ; Michaela KendallSource :
- Philosophical Transactions of the Royal Society B: Biological Sciences [ 0962-8436 ] ; 2015.
Abstract
Bio-nano interactions can be defined as the study of interactions between nanoscale entities and biological systems such as, but not limited to, peptides, proteins, lipids, DNA and other biomolecules, cells and cellular receptors and organisms including humans. Studying bio-nano interactions is particularly useful for understanding
Url:
DOI: 10.1098/rstb.2014.0162
PubMed: 25533104
PubMed Central: 4275916
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PMC:4275916Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Bio-nano interactions can be defined as the study of interactions between nanoscale entities and biological systems such as, but not limited to, peptides, proteins, lipids, DNA and other biomolecules, cells and cellular receptors and organisms including humans. Studying bio-nano interactions is particularly useful for understanding <italic>engineered materials</italic>
that have at least one dimension in the nanoscale. Such materials may consist of discrete particles or nanostructured surfaces. Much of biology functions at the nanoscale; therefore, our ability to manipulate materials such that they are taken up at the nanoscale, and engage biological machinery in a designed and purposeful manner, opens new vistas for more efficient diagnostics, therapeutics (treatments) and tissue regeneration, so-called nanomedicine. Additionally, this ability of nanomaterials to interact with and be taken up by cells allows nanomaterials to be used as probes and tools to advance our understanding of cellular functioning. Yet, as a new technology, assessment of the safety of nanomaterials, and the applicability of existing regulatory frameworks for nanomaterials must be investigated in parallel with development of novel applications. The Royal Society meeting ‘Bio-nano interactions: new tools, insights and impacts' provided an important platform for open dialogue on the current state of knowledge on these issues, bringing together scientists, industry, regulatory and legal experts to concretize existing discourse in science law and policy. This paper summarizes these discussions and the insights that emerged.</p>
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Philos Trans R Soc Lond B Biol Sci</journal-id>
<journal-id journal-id-type="iso-abbrev">Philos. Trans. R. Soc. Lond., B, Biol. Sci</journal-id>
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<title-group><article-title>‘Bio-nano interactions: new tools, insights and impacts’: summary of the Royal Society discussion meeting</article-title>
<alt-title alt-title-type="short">Bionano-interactions</alt-title>
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<contrib-group><contrib contrib-type="author"><name><surname>Lynch</surname>
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<contrib contrib-type="author"><name><surname>Feitshans</surname>
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<aff id="af3"><label>3</label>
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<author-notes><corresp id="cor1">e-mail: <email>i.lynch@bham.ac.uk</email>
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<fn fn-type="other"><p>One contribution of 19 to a discussion meeting issue ‘<ext-link ext-link-type="uri" xlink:href="http://rstb.royalsocietypublishing.org/content/370/1661.toc">Cell adhesion century: culture breakthrough</ext-link>
’.</p>
</fn>
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<pub-date pub-type="ppub"><day>5</day>
<month>2</month>
<year>2015</year>
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<volume>370</volume>
<issue>1661</issue>
<issue-title>Discussion meeting issue ‘Cell adhesion century: culture breakthrough’ organized and edited by Kevin Kendall and Stephen Busby</issue-title>
<elocation-id>20140162</elocation-id>
<permissions><copyright-statement>© 2014 The Author(s) Published by the Royal Society. All rights reserved.</copyright-statement>
<copyright-year>2014</copyright-year>
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<abstract><p>Bio-nano interactions can be defined as the study of interactions between nanoscale entities and biological systems such as, but not limited to, peptides, proteins, lipids, DNA and other biomolecules, cells and cellular receptors and organisms including humans. Studying bio-nano interactions is particularly useful for understanding <italic>engineered materials</italic>
that have at least one dimension in the nanoscale. Such materials may consist of discrete particles or nanostructured surfaces. Much of biology functions at the nanoscale; therefore, our ability to manipulate materials such that they are taken up at the nanoscale, and engage biological machinery in a designed and purposeful manner, opens new vistas for more efficient diagnostics, therapeutics (treatments) and tissue regeneration, so-called nanomedicine. Additionally, this ability of nanomaterials to interact with and be taken up by cells allows nanomaterials to be used as probes and tools to advance our understanding of cellular functioning. Yet, as a new technology, assessment of the safety of nanomaterials, and the applicability of existing regulatory frameworks for nanomaterials must be investigated in parallel with development of novel applications. The Royal Society meeting ‘Bio-nano interactions: new tools, insights and impacts' provided an important platform for open dialogue on the current state of knowledge on these issues, bringing together scientists, industry, regulatory and legal experts to concretize existing discourse in science law and policy. This paper summarizes these discussions and the insights that emerged.</p>
</abstract>
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