Comparison of Doppler ultrasonography and the hepatic venous pressure gradient in assessing portal hypertension in liver cirrhosis
Identifieur interne : 002428 ( Istex/Corpus ); précédent : 002427; suivant : 002429Comparison of Doppler ultrasonography and the hepatic venous pressure gradient in assessing portal hypertension in liver cirrhosis
Auteurs : Yeun Jong Choi ; Soon Koo Baik ; Dong Hoon Park ; Moon Young Kim ; Hyun Soo Kim ; Dong Ki Lee ; Sang Ok Kwon ; Young Ju Kim ; Joong Wha ParkSource :
- Journal of Gastroenterology and Hepatology [ 0815-9319 ] ; 2003-04.
English descriptors
- Teeft :
- Cirrhosis, Doppler, Doppler indices, Doppler ultrasonography, Hemodynamic, Hepatic, Hepatic artery, Hepatic venous pressure gradient, Hepatology, Hvpg, Hypertension, Liver cirrhosis, Portal, Portal hypertension, Portal pressure, Portal vein, Portal venous, Portal venous velocity, Pulsatility, Pulsatility index, Pulsatility indices, Renal, Renal arteries, Renal artery, Resistive, Resistive index, Responder, Splenic, Splenic artery, Terlipressin, Terlipressin administration, Ultrasonography, Variceal, Venous.
Abstract
Background and Aim: This prospective study aimed to determine whether Doppler ultrasonography can represent the hepatic venous pressure gradient (HVPG) as an assessment of the severity of portal hypertension and the response to terlipressin, which reduces the portal pressure in liver cirrhosis.
Methods: The HVPG and the Doppler ultrasonographic parameters, such as the portal venous velocity and the splenic venous velocity, the pulsatility and the resistive index of the hepatic, splenic and renal arteries were measured in 138 patients with liver cirrhosis. The changes in the HVPG and the portal venous velocity after administering terlipressin were evaluated in 43 of the 138 patients. The patients who showed a reduction in the HVPG of more than 20% of the baseline were defined as responders to terlipressin.
Results: None of the Doppler ultrasonographic parameters correlated with the HVPG. Both the HVPG (28.0 ± 19.8%) and the portal venous velocity (29.7 ± 13.2%) showed a significant reduction after terlipressin administration. However, the portal venous velocity decreased significantly, not only in the responders (31.0 ± 12.0%) but also in the non‐responders (25.2 ± 16.4%).
Conclusions: Doppler ultrasonography does not represent the HVPG, and is therefore not suitable for replacing HVPG as a means of assessing the severity of portal hypertension and the response to drugs which reduce the portal pressure in liver cirrhosis.
© 2003 Blackwell Publishing Asia Pty Ltd
Url:
DOI: 10.1046/j.1440-1746.2003.02992.x
Links to Exploration step
ISTEX:8C5CFA35B03C85DD6DF632372F104BBB478ED95ELe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Comparison of Doppler ultrasonography and the hepatic venous pressure gradient in assessing portal hypertension in liver cirrhosis</title><author><name sortKey="Choi, Yeun Jong" sort="Choi, Yeun Jong" uniqKey="Choi Y" first="Yeun Jong" last="Choi">Yeun Jong Choi</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Baik, Soon Koo" sort="Baik, Soon Koo" uniqKey="Baik S" first="Soon Koo" last="Baik">Soon Koo Baik</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Park, Dong Hoon" sort="Park, Dong Hoon" uniqKey="Park D" first="Dong Hoon" last="Park">Dong Hoon Park</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Kim, Moon Young" sort="Kim, Moon Young" uniqKey="Kim M" first="Moon Young" last="Kim">Moon Young Kim</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Kim, Hyun Soo" sort="Kim, Hyun Soo" uniqKey="Kim H" first="Hyun Soo" last="Kim">Hyun Soo Kim</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Lee, Dong Ki" sort="Lee, Dong Ki" uniqKey="Lee D" first="Dong Ki" last="Lee">Dong Ki Lee</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Kwon, Sang Ok" sort="Kwon, Sang Ok" uniqKey="Kwon S" first="Sang Ok" last="Kwon">Sang Ok Kwon</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Kim, Young Ju" sort="Kim, Young Ju" uniqKey="Kim Y" first="Young Ju" last="Kim">Young Ju Kim</name><affiliation><mods:affiliation>Radiology, Yonsei University, Wonju College of Medicine, Wonju, Korea</mods:affiliation></affiliation></author><author><name sortKey="Park, Joong Wha" sort="Park, Joong Wha" uniqKey="Park J" first="Joong Wha" last="Park">Joong Wha Park</name><affiliation><mods:affiliation>Radiology, Yonsei University, Wonju College of Medicine, Wonju, Korea</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:8C5CFA35B03C85DD6DF632372F104BBB478ED95E</idno><date when="2003" year="2003">2003</date><idno type="doi">10.1046/j.1440-1746.2003.02992.x</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-ZHW671TM-N/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">002428</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002428</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Comparison of Doppler ultrasonography and the hepatic venous pressure gradient in assessing portal hypertension in liver cirrhosis</title><author><name sortKey="Choi, Yeun Jong" sort="Choi, Yeun Jong" uniqKey="Choi Y" first="Yeun Jong" last="Choi">Yeun Jong Choi</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Baik, Soon Koo" sort="Baik, Soon Koo" uniqKey="Baik S" first="Soon Koo" last="Baik">Soon Koo Baik</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Park, Dong Hoon" sort="Park, Dong Hoon" uniqKey="Park D" first="Dong Hoon" last="Park">Dong Hoon Park</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Kim, Moon Young" sort="Kim, Moon Young" uniqKey="Kim M" first="Moon Young" last="Kim">Moon Young Kim</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Kim, Hyun Soo" sort="Kim, Hyun Soo" uniqKey="Kim H" first="Hyun Soo" last="Kim">Hyun Soo Kim</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Lee, Dong Ki" sort="Lee, Dong Ki" uniqKey="Lee D" first="Dong Ki" last="Lee">Dong Ki Lee</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Kwon, Sang Ok" sort="Kwon, Sang Ok" uniqKey="Kwon S" first="Sang Ok" last="Kwon">Sang Ok Kwon</name><affiliation><mods:affiliation>Departments of Internal Medicine and</mods:affiliation></affiliation></author><author><name sortKey="Kim, Young Ju" sort="Kim, Young Ju" uniqKey="Kim Y" first="Young Ju" last="Kim">Young Ju Kim</name><affiliation><mods:affiliation>Radiology, Yonsei University, Wonju College of Medicine, Wonju, Korea</mods:affiliation></affiliation></author><author><name sortKey="Park, Joong Wha" sort="Park, Joong Wha" uniqKey="Park J" first="Joong Wha" last="Park">Joong Wha Park</name><affiliation><mods:affiliation>Radiology, Yonsei University, Wonju College of Medicine, Wonju, Korea</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Gastroenterology and Hepatology</title><title level="j" type="alt">JOURNAL OF GASTROENTEROLOGY HEPATOLOGY</title><idno type="ISSN">0815-9319</idno><idno type="eISSN">1440-1746</idno><imprint><biblScope unit="vol">18</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="424">424</biblScope><biblScope unit="page" to="429">429</biblScope><biblScope unit="page-count">6</biblScope><publisher>Blackwell Science Pty</publisher><pubPlace>Melbourne, Australia</pubPlace><date type="published" when="2003-04">2003-04</date></imprint><idno type="ISSN">0815-9319</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0815-9319</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Cirrhosis</term><term>Doppler</term><term>Doppler indices</term><term>Doppler ultrasonography</term><term>Hemodynamic</term><term>Hepatic</term><term>Hepatic artery</term><term>Hepatic venous pressure gradient</term><term>Hepatology</term><term>Hvpg</term><term>Hypertension</term><term>Liver cirrhosis</term><term>Portal</term><term>Portal hypertension</term><term>Portal pressure</term><term>Portal vein</term><term>Portal venous</term><term>Portal venous velocity</term><term>Pulsatility</term><term>Pulsatility index</term><term>Pulsatility indices</term><term>Renal</term><term>Renal arteries</term><term>Renal artery</term><term>Resistive</term><term>Resistive index</term><term>Responder</term><term>Splenic</term><term>Splenic artery</term><term>Terlipressin</term><term>Terlipressin administration</term><term>Ultrasonography</term><term>Variceal</term><term>Venous</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">Background and Aim: This prospective study aimed to determine whether Doppler ultrasonography can represent the hepatic venous pressure gradient (HVPG) as an assessment of the severity of portal hypertension and the response to terlipressin, which reduces the portal pressure in liver cirrhosis.</div><div type="abstract">Methods: The HVPG and the Doppler ultrasonographic parameters, such as the portal venous velocity and the splenic venous velocity, the pulsatility and the resistive index of the hepatic, splenic and renal arteries were measured in 138 patients with liver cirrhosis. The changes in the HVPG and the portal venous velocity after administering terlipressin were evaluated in 43 of the 138 patients. The patients who showed a reduction in the HVPG of more than 20% of the baseline were defined as responders to terlipressin.</div><div type="abstract">Results: None of the Doppler ultrasonographic parameters correlated with the HVPG. Both the HVPG (28.0 ± 19.8%) and the portal venous velocity (29.7 ± 13.2%) showed a significant reduction after terlipressin administration. However, the portal venous velocity decreased significantly, not only in the responders (31.0 ± 12.0%) but also in the non‐responders (25.2 ± 16.4%).</div><div type="abstract">Conclusions: Doppler ultrasonography does not represent the HVPG, and is therefore not suitable for replacing HVPG as a means of assessing the severity of portal hypertension and the response to drugs which reduce the portal pressure in liver cirrhosis.</div><div type="abstract">© 2003 Blackwell Publishing Asia Pty Ltd</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>hepatic</json:string><json:string>venous</json:string><json:string>hvpg</json:string><json:string>hypertension</json:string><json:string>portal hypertension</json:string><json:string>cirrhosis</json:string><json:string>splenic</json:string><json:string>terlipressin</json:string><json:string>doppler</json:string><json:string>ultrasonography</json:string><json:string>responder</json:string><json:string>doppler ultrasonography</json:string><json:string>portal</json:string><json:string>portal venous velocity</json:string><json:string>hepatic venous pressure gradient</json:string><json:string>pulsatility</json:string><json:string>hemodynamic</json:string><json:string>hepatology</json:string><json:string>portal pressure</json:string><json:string>liver cirrhosis</json:string><json:string>hepatic artery</json:string><json:string>variceal</json:string><json:string>resistive</json:string><json:string>portal vein</json:string><json:string>pulsatility index</json:string><json:string>portal venous</json:string><json:string>renal</json:string><json:string>renal arteries</json:string><json:string>terlipressin administration</json:string><json:string>doppler indices</json:string><json:string>resistive index</json:string><json:string>splenic artery</json:string><json:string>pulsatility indices</json:string><json:string>renal artery</json:string></teeft></keywords><author><json:item><name>YEUN JONG CHOI</name><affiliations><json:string>Departments of Internal Medicine and</json:string></affiliations></json:item><json:item><name>SOON KOO BAIK</name><affiliations><json:string>Departments of Internal Medicine and</json:string></affiliations></json:item><json:item><name>DONG HOON PARK</name><affiliations><json:string>Departments of Internal Medicine and</json:string></affiliations></json:item><json:item><name>MOON YOUNG KIM</name><affiliations><json:string>Departments of Internal Medicine and</json:string></affiliations></json:item><json:item><name>HYUN SOO KIM</name><affiliations><json:string>Departments of Internal Medicine and</json:string></affiliations></json:item><json:item><name>DONG KI LEE</name><affiliations><json:string>Departments of Internal Medicine and</json:string></affiliations></json:item><json:item><name>SANG OK KWON</name><affiliations><json:string>Departments of Internal Medicine and</json:string></affiliations></json:item><json:item><name>YOUNG JU KIM</name><affiliations><json:string>Radiology, Yonsei University, Wonju College of Medicine, Wonju, Korea</json:string></affiliations></json:item><json:item><name>JOONG WHA PARK</name><affiliations><json:string>Radiology, Yonsei University, Wonju College of Medicine, Wonju, Korea</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Doppler ultrasonography</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>hepatic venous pressure gradient</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>liver cirrhosis</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>portal hypertension</value></json:item></subject><articleId><json:string>JGH2992</json:string></articleId><arkIstex>ark:/67375/WNG-ZHW671TM-N</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Background and Aim: This prospective study aimed to determine whether Doppler ultrasonography can represent the hepatic venous pressure gradient (HVPG) as an assessment of the severity of portal hypertension and the response to terlipressin, which reduces the portal pressure in liver cirrhosis.</abstract><qualityIndicators><score>5.54</score><pdfWordCount>3036</pdfWordCount><pdfCharCount>19489</pdfCharCount><pdfVersion>1.4</pdfVersion><pdfPageCount>6</pdfPageCount><pdfPageSize>595 x 779.638 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractWordCount>42</abstractWordCount><abstractCharCount>295</abstractCharCount><keywordCount>4</keywordCount></qualityIndicators><title>Comparison of Doppler ultrasonography and the hepatic venous pressure gradient in assessing portal hypertension in liver cirrhosis</title><pmid><json:string>12653891</json:string></pmid><genre><json:string>article</json:string></genre><host><title>Journal of Gastroenterology and Hepatology</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1440-1746</json:string></doi><issn><json:string>0815-9319</json:string></issn><eissn><json:string>1440-1746</json:string></eissn><publisherId><json:string>JGH</json:string></publisherId><volume>18</volume><issue>4</issue><pages><first>424</first><last>429</last><total>6</total></pages><genre><json:string>journal</json:string></genre></host><namedEntities><unitex><date></date><geogName></geogName><orgName></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName></persName><placeName></placeName><ref_url></ref_url><ref_bibl></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-ZHW671TM-N</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - gastroenterology & hepatology</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - clinical medicine</json:string><json:string>3 - gastroenterology & hepatology</json:string></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Medicine</json:string><json:string>3 - Gastroenterology</json:string><json:string>1 - Health Sciences</json:string><json:string>2 - Medicine</json:string><json:string>3 - Hepatology</json:string></scopus></categories><publicationDate>2003</publicationDate><copyrightDate>2003</copyrightDate><doi><json:string>10.1046/j.1440-1746.2003.02992.x</json:string></doi><id>8C5CFA35B03C85DD6DF632372F104BBB478ED95E</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-ZHW671TM-N/fulltext.pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-ZHW671TM-N/bundle.zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/ark:/67375/WNG-ZHW671TM-N/fulltext.tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">Comparison of Doppler ultrasonography and the hepatic venous pressure gradient in assessing portal hypertension in liver cirrhosis</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Science Pty</publisher><pubPlace>Melbourne, Australia</pubPlace><date type="published" when="2003-04"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Comparison of Doppler ultrasonography and the hepatic venous pressure gradient in assessing portal hypertension in liver cirrhosis</title><title level="a" type="short">Doppler ultrasonography in portal hypertension</title><author xml:id="author-0000"><persName><forename type="first">YEUN JONG</forename><surname>CHOI</surname></persName><affiliation><orgName type="department">Departments of Internal Medicine and</orgName></affiliation></author><author xml:id="author-0001"><persName><forename type="first">SOON KOO</forename><surname>BAIK</surname></persName><affiliation><orgName type="department">Departments of Internal Medicine and</orgName></affiliation></author><author xml:id="author-0002"><persName><forename type="first">DONG HOON</forename><surname>PARK</surname></persName><affiliation><orgName type="department">Departments of Internal Medicine and</orgName></affiliation></author><author xml:id="author-0003"><persName><forename type="first">MOON YOUNG</forename><surname>KIM</surname></persName><affiliation><orgName type="department">Departments of Internal Medicine and</orgName></affiliation></author><author xml:id="author-0004"><persName><forename type="first">HYUN SOO</forename><surname>KIM</surname></persName><affiliation><orgName type="department">Departments of Internal Medicine and</orgName></affiliation></author><author xml:id="author-0005"><persName><forename type="first">DONG KI</forename><surname>LEE</surname></persName><affiliation><orgName type="department">Departments of Internal Medicine and</orgName></affiliation></author><author xml:id="author-0006"><persName><forename type="first">SANG OK</forename><surname>KWON</surname></persName><affiliation><orgName type="department">Departments of Internal Medicine and</orgName></affiliation></author><author xml:id="author-0007"><persName><forename type="first">YOUNG JU</forename><surname>KIM</surname></persName><affiliation><address><addrLine>Radiology</addrLine><addrLine>Yonsei University</addrLine><addrLine>Wonju College of Medicine</addrLine><addrLine>Wonju</addrLine><country key="KR">KOREA, REPUBLIC OF</country></address></affiliation></author><author xml:id="author-0008"><persName><forename type="first">JOONG WHA</forename><surname>PARK</surname></persName><affiliation><address><addrLine>Radiology</addrLine><addrLine>Yonsei University</addrLine><addrLine>Wonju College of Medicine</addrLine><addrLine>Wonju</addrLine><country key="KR">KOREA, REPUBLIC OF</country></address></affiliation></author><idno type="istex">8C5CFA35B03C85DD6DF632372F104BBB478ED95E</idno><idno type="ark">ark:/67375/WNG-ZHW671TM-N</idno><idno type="DOI">10.1046/j.1440-1746.2003.02992.x</idno><idno type="unit">JGH2992</idno><idno type="toTypesetVersion">file:JGH.JGH2992.pdf</idno></analytic><monogr><title level="j" type="main">Journal of Gastroenterology and Hepatology</title><title level="j" type="alt">JOURNAL OF GASTROENTEROLOGY HEPATOLOGY</title><idno type="pISSN">0815-9319</idno><idno type="eISSN">1440-1746</idno><idno type="book-DOI">10.1111/(ISSN)1440-1746</idno><idno type="book-part-DOI">10.1111/jgh.2003.18.issue-4</idno><idno type="product">JGH</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">18</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="424">424</biblScope><biblScope unit="page" to="429">429</biblScope><biblScope unit="page-count">6</biblScope><publisher>Blackwell Science Pty</publisher><pubPlace>Melbourne, Australia</pubPlace><date type="published" when="2003-04"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><head>Abstract</head><p><hi rend="italic">Background and Aim:</hi> This prospective study aimed to determine whether Doppler ultrasonography can represent the hepatic venous pressure gradient (HVPG) as an assessment of the severity of portal hypertension and the response to terlipressin, which reduces the portal pressure in liver cirrhosis.</p><p><hi rend="italic">Methods:</hi> The HVPG and the Doppler ultrasonographic parameters, such as the portal venous velocity and the splenic venous velocity, the pulsatility and the resistive index of the hepatic, splenic and renal arteries were measured in 138 patients with liver cirrhosis. The changes in the HVPG and the portal venous velocity after administering terlipressin were evaluated in 43 of the 138 patients. The patients who showed a reduction in the HVPG of more than 20% of the baseline were defined as responders to terlipressin.</p><p><hi rend="italic">Results:</hi> None of the Doppler ultrasonographic parameters correlated with the HVPG. Both the HVPG (28.0 ± 19.8%) and the portal venous velocity (29.7 ± 13.2%) showed a significant reduction after terlipressin administration. However, the portal venous velocity decreased significantly, not only in the responders (31.0 ± 12.0%) but also in the non‐responders (25.2 ± 16.4%).</p><p><hi rend="italic">Conclusions:</hi> Doppler ultrasonography does not represent the HVPG, and is therefore not suitable for replacing HVPG as a means of assessing the severity of portal hypertension and the response to drugs which reduce the portal pressure in liver cirrhosis.</p><p>© 2003 Blackwell Publishing Asia Pty Ltd</p></abstract><textClass><keywords xml:lang="en"><term xml:id="k1">Doppler ultrasonography</term><term xml:id="k2">hepatic venous pressure gradient</term><term xml:id="k3">liver cirrhosis</term><term xml:id="k4">portal hypertension</term></keywords><keywords rend="tocHeading1"><term>Cirrhosis and Hepatocellular Carcinoma</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-ZHW671TM-N/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Science Pty</publisherName><publisherLoc>Melbourne, Australia</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1440-1746</doi><issn type="print">0815-9319</issn><issn type="electronic">1440-1746</issn><idGroup><id type="product" value="JGH"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="JOURNAL OF GASTROENTEROLOGY HEPATOLOGY">Journal of Gastroenterology and Hepatology</title></titleGroup></publicationMeta><publicationMeta level="part" position="04004"><doi origin="wiley">10.1111/jgh.2003.18.issue-4</doi><numberingGroup><numbering type="journalVolume" number="18">18</numbering><numbering type="journalIssue" number="4">4</numbering></numberingGroup><coverDate startDate="2003-04">April 2003</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="0042400" status="forIssue"><doi origin="wiley">10.1046/j.1440-1746.2003.02992.x</doi><idGroup><id type="unit" value="JGH2992"></id></idGroup><countGroup><count type="pageTotal" number="6"></count></countGroup><titleGroup><title type="tocHeading1">Cirrhosis and Hepatocellular Carcinoma</title></titleGroup><eventGroup><event type="firstOnline" date="2008-09-23"></event><event type="publishedOnlineFinalForm" date="2008-09-23"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.4 mode:FullText source:FullText result:FullText" date="2010-03-30"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-30"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-30"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="424">424</numbering><numbering type="pageLast" number="429">429</numbering></numberingGroup><correspondenceTo> Dr Soon Koo Baik, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Wonju Christian Hospital, Yonsei University, Wonju College of Medicine, 162 Ilsan‐Dong, Wonju 220–701, South Korea. Email: <email>skbaik@wonju.yonsei.ac.kr</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:JGH.JGH2992.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Accepted for publication 31 October 2002.</unparsedEditorialHistory><countGroup><count type="figureTotal" number="0"></count><count type="tableTotal" number="3"></count><count type="formulaTotal" number="0"></count><count type="referenceTotal" number="22"></count><count type="wordTotal" number="2615"></count><count type="linksPubMed" number="12"></count><count type="linksCrossRef" number="0"></count></countGroup><titleGroup><title type="main">Comparison of Doppler ultrasonography and the hepatic venous pressure gradient in assessing portal hypertension in liver cirrhosis</title><title type="shortAuthors">YJ Choi <i>et al.</i></title><title type="short">Doppler ultrasonography in portal hypertension</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1"><personName><givenNames>YEUN JONG</givenNames><familyName>CHOI</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a1"><personName><givenNames>SOON KOO</givenNames><familyName>BAIK</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a1"><personName><givenNames>DONG HOON</givenNames><familyName>PARK</familyName></personName></creator><creator creatorRole="author" xml:id="cr4" affiliationRef="#a1"><personName><givenNames>MOON YOUNG</givenNames><familyName>KIM</familyName></personName></creator><creator creatorRole="author" xml:id="cr5" affiliationRef="#a1"><personName><givenNames>HYUN SOO</givenNames><familyName>KIM</familyName></personName></creator><creator creatorRole="author" xml:id="cr6" affiliationRef="#a1"><personName><givenNames>DONG KI</givenNames><familyName>LEE</familyName></personName></creator><creator creatorRole="author" xml:id="cr7" affiliationRef="#a1"><personName><givenNames>SANG OK</givenNames><familyName>KWON</familyName></personName></creator><creator creatorRole="author" xml:id="cr8" affiliationRef="#a2"><personName><givenNames>YOUNG JU</givenNames><familyName>KIM</familyName></personName></creator><creator creatorRole="author" xml:id="cr9" affiliationRef="#a2"><personName><givenNames>JOONG WHA</givenNames><familyName>PARK</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1"><unparsedAffiliation>Departments of Internal Medicine and</unparsedAffiliation></affiliation><affiliation xml:id="a2"><unparsedAffiliation>Radiology, Yonsei University, Wonju College of Medicine, Wonju, Korea</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">Doppler ultrasonography</keyword><keyword xml:id="k2">hepatic venous pressure gradient</keyword><keyword xml:id="k3">liver cirrhosis</keyword><keyword xml:id="k4">portal hypertension</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p><b>Background and Aim:</b> This prospective study aimed to determine whether Doppler ultrasonography can represent the hepatic venous pressure gradient (HVPG) as an assessment of the severity of portal hypertension and the response to terlipressin, which reduces the portal pressure in liver cirrhosis.</p><p><b>Methods:</b> The HVPG and the Doppler ultrasonographic parameters, such as the portal venous velocity and the splenic venous velocity, the pulsatility and the resistive index of the hepatic, splenic and renal arteries were measured in 138 patients with liver cirrhosis. The changes in the HVPG and the portal venous velocity after administering terlipressin were evaluated in 43 of the 138 patients. The patients who showed a reduction in the HVPG of more than 20% of the baseline were defined as responders to terlipressin.</p><p><b>Results:</b> None of the Doppler ultrasonographic parameters correlated with the HVPG. Both the HVPG (28.0 ± 19.8%) and the portal venous velocity (29.7 ± 13.2%) showed a significant reduction after terlipressin administration. However, the portal venous velocity decreased significantly, not only in the responders (31.0 ± 12.0%) but also in the non‐responders (25.2 ± 16.4%).</p><p><b>Conclusions:</b> Doppler ultrasonography does not represent the HVPG, and is therefore not suitable for replacing HVPG as a means of assessing the severity of portal hypertension and the response to drugs which reduce the portal pressure in liver cirrhosis.</p><p>© 2003 Blackwell Publishing Asia Pty Ltd</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Comparison of Doppler ultrasonography and the hepatic venous pressure gradient in assessing portal hypertension in liver cirrhosis</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Doppler ultrasonography in portal hypertension</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Comparison of Doppler ultrasonography and the hepatic venous pressure gradient in assessing portal hypertension in liver cirrhosis</title></titleInfo><name type="personal"><namePart type="given">YEUN JONG</namePart><namePart type="family">CHOI</namePart><affiliation>Departments of Internal Medicine and</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SOON KOO</namePart><namePart type="family">BAIK</namePart><affiliation>Departments of Internal Medicine and</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DONG HOON</namePart><namePart type="family">PARK</namePart><affiliation>Departments of Internal Medicine and</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MOON YOUNG</namePart><namePart type="family">KIM</namePart><affiliation>Departments of Internal Medicine and</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HYUN SOO</namePart><namePart type="family">KIM</namePart><affiliation>Departments of Internal Medicine and</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DONG KI</namePart><namePart type="family">LEE</namePart><affiliation>Departments of Internal Medicine and</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SANG OK</namePart><namePart type="family">KWON</namePart><affiliation>Departments of Internal Medicine and</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">YOUNG JU</namePart><namePart type="family">KIM</namePart><affiliation>Radiology, Yonsei University, Wonju College of Medicine, Wonju, Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JOONG WHA</namePart><namePart type="family">PARK</namePart><affiliation>Radiology, Yonsei University, Wonju College of Medicine, Wonju, Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Science Pty</publisher><place><placeTerm type="text">Melbourne, Australia</placeTerm></place><dateIssued encoding="w3cdtf">2003-04</dateIssued><edition>Accepted for publication 31 October 2002.</edition><copyrightDate encoding="w3cdtf">2003</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">0</extent><extent unit="tables">3</extent><extent unit="formulas">0</extent><extent unit="references">22</extent><extent unit="linksCrossRef">0</extent><extent unit="words">2615</extent></physicalDescription><abstract>Background and Aim: This prospective study aimed to determine whether Doppler ultrasonography can represent the hepatic venous pressure gradient (HVPG) as an assessment of the severity of portal hypertension and the response to terlipressin, which reduces the portal pressure in liver cirrhosis.</abstract><abstract>Methods: The HVPG and the Doppler ultrasonographic parameters, such as the portal venous velocity and the splenic venous velocity, the pulsatility and the resistive index of the hepatic, splenic and renal arteries were measured in 138 patients with liver cirrhosis. The changes in the HVPG and the portal venous velocity after administering terlipressin were evaluated in 43 of the 138 patients. The patients who showed a reduction in the HVPG of more than 20% of the baseline were defined as responders to terlipressin.</abstract><abstract>Results: None of the Doppler ultrasonographic parameters correlated with the HVPG. Both the HVPG (28.0 ± 19.8%) and the portal venous velocity (29.7 ± 13.2%) showed a significant reduction after terlipressin administration. However, the portal venous velocity decreased significantly, not only in the responders (31.0 ± 12.0%) but also in the non‐responders (25.2 ± 16.4%).</abstract><abstract>Conclusions: Doppler ultrasonography does not represent the HVPG, and is therefore not suitable for replacing HVPG as a means of assessing the severity of portal hypertension and the response to drugs which reduce the portal pressure in liver cirrhosis.</abstract><abstract>© 2003 Blackwell Publishing Asia Pty Ltd</abstract><subject lang="en"><genre>keywords</genre><topic>Doppler ultrasonography</topic><topic>hepatic venous pressure gradient</topic><topic>liver cirrhosis</topic><topic>portal hypertension</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Gastroenterology and Hepatology</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><identifier type="ISSN">0815-9319</identifier><identifier type="eISSN">1440-1746</identifier><identifier type="DOI">10.1111/(ISSN)1440-1746</identifier><identifier type="PublisherID">JGH</identifier><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><detail type="issue"><caption>no.</caption><number>4</number></detail><extent unit="pages"><start>424</start><end>429</end><total>6</total></extent></part></relatedItem><identifier type="istex">8C5CFA35B03C85DD6DF632372F104BBB478ED95E</identifier><identifier type="ark">ark:/67375/WNG-ZHW671TM-N</identifier><identifier type="DOI">10.1046/j.1440-1746.2003.02992.x</identifier><identifier type="ArticleID">JGH2992</identifier><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Blackwell Science Pty</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-ZHW671TM-N/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Informatique/explor/SgmlV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002428 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 002428 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Informatique
|area= SgmlV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:8C5CFA35B03C85DD6DF632372F104BBB478ED95E
|texte= Comparison of Doppler ultrasonography and the hepatic venous pressure gradient in assessing portal hypertension in liver cirrhosis
}}
| This area was generated with Dilib version V0.6.33. |  |