The effect of transcranial direct current stimulation on the expression of the flexor synergy in the paretic arm in chronic stroke is dependent on shoulder abduction loading.
Identifieur interne : 000334 ( PubMed/Corpus ); précédent : 000333; suivant : 000335The effect of transcranial direct current stimulation on the expression of the flexor synergy in the paretic arm in chronic stroke is dependent on shoulder abduction loading.
Auteurs : Jun Yao ; Justin Drogos ; Fleur Veltink ; Caitlyn Anderson ; Janny Concha Urday Zaa ; Laura Imming Hanson ; Julius P A. DewaldSource :
- Frontiers in human neuroscience [ 1662-5161 ] ; 2015.
Abstract
Reaching ability of the paretic upper extremity in individuals with stroke decreases with increased shoulder abduction (SABD) loads. Transcranial direct current stimulation (tDCS) has been implemented to improve movement ability following stroke. However, results from previous studies vary, perhaps due to the influence of impairment level and the type of motor tasks that were used to study the effects of tDCS. This study specifically examines the impact of SABD loading on the effects of tDCS in 9 individuals with moderate to severe chronic stroke. In 3 different sessions, participants repeated a reaching assessment with various SABD loads (supported on a haptic table, 25%, and 50% of maximum voluntary SABD torque) in random order, pre and post one of the following 15-min tDCS protocols: anodal stimulation of lesioned M1, cathodal stimulation of non-lesioned M1, or anodal stimulation of non-lesioned M1. Sham stimulation was also conducted preceding one of the tDCS sessions. The averaged maximum reaching distance over valid trials was calculated for each condition. We observed significant interactions between SABD load, tDCS protocol and time (i.e., pre or post-tDCS). Post hoc test showed that anodal stimulation of the lesioned M1 caused a clear trend (p = 0.058) of increasing the reaching ability at a medium level of SABD loading (25%), but not for higher loads (50%). This suggests that anodal stimulation increases residual corticospinal tract activity, which successfully increases reaching ability at moderate loads; however, is insufficient to make significant changes at higher SABD loads. We also found that cathodal stimulation of the non-lesioned M1 significantly (p = 0.018) decreased the reaching distance at a high level of SABD loading (50%). This study demonstrated, for the first time, that the effect of tDCS on the reaching ability is dependent on SABD loads in individuals with moderate to severe stroke.
DOI: 10.3389/fnhum.2015.00262
PubMed: 26029081
Links to Exploration step
pubmed:26029081Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The effect of transcranial direct current stimulation on the expression of the flexor synergy in the paretic arm in chronic stroke is dependent on shoulder abduction loading.</title><author><name sortKey="Yao, Jun" sort="Yao, Jun" uniqKey="Yao J" first="Jun" last="Yao">Jun Yao</name><affiliation><nlm:affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Drogos, Justin" sort="Drogos, Justin" uniqKey="Drogos J" first="Justin" last="Drogos">Justin Drogos</name><affiliation><nlm:affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Veltink, Fleur" sort="Veltink, Fleur" uniqKey="Veltink F" first="Fleur" last="Veltink">Fleur Veltink</name><affiliation><nlm:affiliation>The Medical Faculty of the Radboud University Nijmegen, Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Anderson, Caitlyn" sort="Anderson, Caitlyn" uniqKey="Anderson C" first="Caitlyn" last="Anderson">Caitlyn Anderson</name><affiliation><nlm:affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Concha Urday Zaa, Janny" sort="Concha Urday Zaa, Janny" uniqKey="Concha Urday Zaa J" first="Janny" last="Concha Urday Zaa">Janny Concha Urday Zaa</name><affiliation><nlm:affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Hanson, Laura Imming" sort="Hanson, Laura Imming" uniqKey="Hanson L" first="Laura Imming" last="Hanson">Laura Imming Hanson</name><affiliation><nlm:affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Dewald, Julius P A" sort="Dewald, Julius P A" uniqKey="Dewald J" first="Julius P A" last="Dewald">Julius P A. Dewald</name><affiliation><nlm:affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA ; Department of Biomedical Engineering, Northwestern University Chicago, IL, USA ; Department of Physical Medicine and Rehabilitation, Northwestern University Chicago, IL, USA.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="doi">10.3389/fnhum.2015.00262</idno><idno type="RBID">pubmed:26029081</idno><idno type="pmid">26029081</idno><idno type="wicri:Area/PubMed/Corpus">000334</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The effect of transcranial direct current stimulation on the expression of the flexor synergy in the paretic arm in chronic stroke is dependent on shoulder abduction loading.</title><author><name sortKey="Yao, Jun" sort="Yao, Jun" uniqKey="Yao J" first="Jun" last="Yao">Jun Yao</name><affiliation><nlm:affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Drogos, Justin" sort="Drogos, Justin" uniqKey="Drogos J" first="Justin" last="Drogos">Justin Drogos</name><affiliation><nlm:affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Veltink, Fleur" sort="Veltink, Fleur" uniqKey="Veltink F" first="Fleur" last="Veltink">Fleur Veltink</name><affiliation><nlm:affiliation>The Medical Faculty of the Radboud University Nijmegen, Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Anderson, Caitlyn" sort="Anderson, Caitlyn" uniqKey="Anderson C" first="Caitlyn" last="Anderson">Caitlyn Anderson</name><affiliation><nlm:affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Concha Urday Zaa, Janny" sort="Concha Urday Zaa, Janny" uniqKey="Concha Urday Zaa J" first="Janny" last="Concha Urday Zaa">Janny Concha Urday Zaa</name><affiliation><nlm:affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Hanson, Laura Imming" sort="Hanson, Laura Imming" uniqKey="Hanson L" first="Laura Imming" last="Hanson">Laura Imming Hanson</name><affiliation><nlm:affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Dewald, Julius P A" sort="Dewald, Julius P A" uniqKey="Dewald J" first="Julius P A" last="Dewald">Julius P A. Dewald</name><affiliation><nlm:affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA ; Department of Biomedical Engineering, Northwestern University Chicago, IL, USA ; Department of Physical Medicine and Rehabilitation, Northwestern University Chicago, IL, USA.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Frontiers in human neuroscience</title><idno type="eISSN">1662-5161</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Reaching ability of the paretic upper extremity in individuals with stroke decreases with increased shoulder abduction (SABD) loads. Transcranial direct current stimulation (tDCS) has been implemented to improve movement ability following stroke. However, results from previous studies vary, perhaps due to the influence of impairment level and the type of motor tasks that were used to study the effects of tDCS. This study specifically examines the impact of SABD loading on the effects of tDCS in 9 individuals with moderate to severe chronic stroke. In 3 different sessions, participants repeated a reaching assessment with various SABD loads (supported on a haptic table, 25%, and 50% of maximum voluntary SABD torque) in random order, pre and post one of the following 15-min tDCS protocols: anodal stimulation of lesioned M1, cathodal stimulation of non-lesioned M1, or anodal stimulation of non-lesioned M1. Sham stimulation was also conducted preceding one of the tDCS sessions. The averaged maximum reaching distance over valid trials was calculated for each condition. We observed significant interactions between SABD load, tDCS protocol and time (i.e., pre or post-tDCS). Post hoc test showed that anodal stimulation of the lesioned M1 caused a clear trend (p = 0.058) of increasing the reaching ability at a medium level of SABD loading (25%), but not for higher loads (50%). This suggests that anodal stimulation increases residual corticospinal tract activity, which successfully increases reaching ability at moderate loads; however, is insufficient to make significant changes at higher SABD loads. We also found that cathodal stimulation of the non-lesioned M1 significantly (p = 0.018) decreased the reaching distance at a high level of SABD loading (50%). This study demonstrated, for the first time, that the effect of tDCS on the reaching ability is dependent on SABD loads in individuals with moderate to severe stroke.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="PubMed-not-MEDLINE"><PMID Version="1">26029081</PMID><DateCreated><Year>2015</Year><Month>06</Month><Day>01</Day></DateCreated><DateCompleted><Year>2015</Year><Month>06</Month><Day>01</Day></DateCompleted><DateRevised><Year>2016</Year><Month>04</Month><Day>15</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1662-5161</ISSN><JournalIssue CitedMedium="Print"><Volume>9</Volume><PubDate><Year>2015</Year></PubDate></JournalIssue><Title>Frontiers in human neuroscience</Title><ISOAbbreviation>Front Hum Neurosci</ISOAbbreviation></Journal><ArticleTitle>The effect of transcranial direct current stimulation on the expression of the flexor synergy in the paretic arm in chronic stroke is dependent on shoulder abduction loading.</ArticleTitle><Pagination><MedlinePgn>262</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.3389/fnhum.2015.00262</ELocationID><Abstract><AbstractText>Reaching ability of the paretic upper extremity in individuals with stroke decreases with increased shoulder abduction (SABD) loads. Transcranial direct current stimulation (tDCS) has been implemented to improve movement ability following stroke. However, results from previous studies vary, perhaps due to the influence of impairment level and the type of motor tasks that were used to study the effects of tDCS. This study specifically examines the impact of SABD loading on the effects of tDCS in 9 individuals with moderate to severe chronic stroke. In 3 different sessions, participants repeated a reaching assessment with various SABD loads (supported on a haptic table, 25%, and 50% of maximum voluntary SABD torque) in random order, pre and post one of the following 15-min tDCS protocols: anodal stimulation of lesioned M1, cathodal stimulation of non-lesioned M1, or anodal stimulation of non-lesioned M1. Sham stimulation was also conducted preceding one of the tDCS sessions. The averaged maximum reaching distance over valid trials was calculated for each condition. We observed significant interactions between SABD load, tDCS protocol and time (i.e., pre or post-tDCS). Post hoc test showed that anodal stimulation of the lesioned M1 caused a clear trend (p = 0.058) of increasing the reaching ability at a medium level of SABD loading (25%), but not for higher loads (50%). This suggests that anodal stimulation increases residual corticospinal tract activity, which successfully increases reaching ability at moderate loads; however, is insufficient to make significant changes at higher SABD loads. We also found that cathodal stimulation of the non-lesioned M1 significantly (p = 0.018) decreased the reaching distance at a high level of SABD loading (50%). This study demonstrated, for the first time, that the effect of tDCS on the reaching ability is dependent on SABD loads in individuals with moderate to severe stroke.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Yao</LastName><ForeName>Jun</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Drogos</LastName><ForeName>Justin</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Veltink</LastName><ForeName>Fleur</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>The Medical Faculty of the Radboud University Nijmegen, Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Anderson</LastName><ForeName>Caitlyn</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Concha Urday Zaa</LastName><ForeName>Janny</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hanson</LastName><ForeName>Laura Imming</ForeName><Initials>LI</Initials><AffiliationInfo><Affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dewald</LastName><ForeName>Julius P A</ForeName><Initials>JP</Initials><AffiliationInfo><Affiliation>Department of Physical Therapy and Human Movement Sciences, Northwestern University Chicago, IL, USA ; Department of Biomedical Engineering, Northwestern University Chicago, IL, USA ; Department of Physical Medicine and Rehabilitation, Northwestern University Chicago, IL, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>R01 HD039343</GrantID><Acronym>HD</Acronym><Agency>NICHD NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>05</Month><Day>11</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Front Hum Neurosci</MedlineTA><NlmUniqueID>101477954</NlmUniqueID><ISSNLinking>1662-5161</ISSNLinking></MedlineJournalInfo><OtherID Source="NLM">PMC4426705</OtherID><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">flexion synergy</Keyword><Keyword MajorTopicYN="N">motor control disorders</Keyword><Keyword MajorTopicYN="N">reaching arm movements</Keyword><Keyword MajorTopicYN="N">stroke</Keyword><Keyword MajorTopicYN="N">transcranial direct current stimulation</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="ecollection"><Year>2015</Year><Month></Month><Day></Day></PubMedPubDate><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>1</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>4</Month><Day>22</Day></PubMedPubDate><PubMedPubDate PubStatus="epublish"><Year>2015</Year><Month>5</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>6</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>6</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>6</Month><Day>2</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="doi">10.3389/fnhum.2015.00262</ArticleId><ArticleId IdType="pubmed">26029081</ArticleId><ArticleId IdType="pmc">PMC4426705</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000334 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000334 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= HapticV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:26029081
|texte= The effect of transcranial direct current stimulation on the expression of the flexor synergy in the paretic arm in chronic stroke is dependent on shoulder abduction loading.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:26029081" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a HapticV1
| This area was generated with Dilib version V0.6.23. |  |