The Lens Capsule
Identifieur interne : 000F14 ( Ncbi/Merge ); précédent : 000F13; suivant : 000F15The Lens Capsule
Auteurs : Brian P. Danysh ; Melinda K. DuncanSource :
- Experimental eye research [ 0014-4835 ] ; 2008.
Abstract
The lens capsule is a modified basement membrane that completely surrounds the ocular lens. It is known that this extracellular matrix is important for both the structure and biomechanics of the lens in addition to providing informational cues to maintain lens cell phenotype. This review covers the development and structure of the lens capsule, lens diseases associated with mutations in extracellular matrix genes and the role of the capsule in lens function including those proposed for visual accommodation, selective permeability to infectious agents, and cell signaling.
Url:
DOI: 10.1016/j.exer.2008.08.002
PubMed: 18773892
PubMed Central: 2674021
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PMC:2674021Le document en format XML
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<front><journal-meta><journal-id journal-id-type="nlm-journal-id">0370707</journal-id><journal-id journal-id-type="pubmed-jr-id">3647</journal-id><journal-id journal-id-type="nlm-ta">Exp Eye Res</journal-id><journal-title>Experimental eye research</journal-title><issn pub-type="ppub">0014-4835</issn><issn pub-type="epub">1096-0007</issn></journal-meta><article-meta><article-id pub-id-type="pmid">18773892</article-id><article-id pub-id-type="pmc">2674021</article-id><article-id pub-id-type="doi">10.1016/j.exer.2008.08.002</article-id><article-id pub-id-type="manuscript">NIHMS105801</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>The Lens Capsule</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Danysh</surname><given-names>Brian P.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Duncan</surname><given-names>Melinda K.</given-names></name><xref ref-type="corresp" rid="CR1">*</xref></contrib><aff id="A1">Department of Biological Sciences, University of Delaware, Newark, DE 19716 USA</aff></contrib-group><author-notes><corresp id="CR1"><label>*</label>To whom all the correspondence should be addressed: Melinda K. DuncanDepartment of Biological Sciences University of DelawareNewark, DE 19716 Telephone: (302) 831-0533 Fax: (302) 831-2281 E-mail address: <email>duncanm@udel.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>30</day><month>3</month><year>2009</year></pub-date><pub-date pub-type="epub"><day>16</day><month>8</month><year>2008</year></pub-date><pub-date pub-type="ppub"><month>2</month><year>2009</year></pub-date><pub-date pub-type="pmc-release"><day>1</day><month>2</month><year>2010</year></pub-date><volume>88</volume><issue>2</issue><fpage>151</fpage><lpage>164</lpage><abstract><p id="P1">The lens capsule is a modified basement membrane that completely surrounds the ocular lens. It is known that this extracellular matrix is important for both the structure and biomechanics of the lens in addition to providing informational cues to maintain lens cell phenotype. This review covers the development and structure of the lens capsule, lens diseases associated with mutations in extracellular matrix genes and the role of the capsule in lens function including those proposed for visual accommodation, selective permeability to infectious agents, and cell signaling.</p></abstract><contract-num rid="EY1">R01 EY015279-05</contract-num><contract-sponsor id="EY1">National Eye Institute : NEI</contract-sponsor></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Danysh, Brian P" sort="Danysh, Brian P" uniqKey="Danysh B" first="Brian P." last="Danysh">Brian P. Danysh</name><name sortKey="Duncan, Melinda K" sort="Duncan, Melinda K" uniqKey="Duncan M" first="Melinda K." last="Duncan">Melinda K. Duncan</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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