Multisensory plasticity in adulthood: cross-modal experience enhances neuronal excitability and exposes silent inputs
Identifieur interne : 002315 ( Ncbi/Curation ); précédent : 002314; suivant : 002316Multisensory plasticity in adulthood: cross-modal experience enhances neuronal excitability and exposes silent inputs
Auteurs : Liping Yu ; Benjamin A. Rowland ; Jinghong Xu ; Barry E. SteinSource :
- Journal of Neurophysiology [ 0022-3077 ] ; 2012.
Abstract
Multisensory superior colliculus neurons in cats were found to retain substantial plasticity to short-term, site-specific experience with cross-modal stimuli well into adulthood. Following cross-modal exposure trials, these neurons substantially increased their sensitivity to the cross-modal stimulus configuration as well as to its individual component stimuli. In many cases, the exposure experience also revealed a previously ineffective or “silent” input channel, rendering it overtly responsive. These experience-induced changes required relatively few exposure trials and could be retained for more than 1 h. However, their induction was generally restricted to experience with cross-modal stimuli. Only rarely were they induced by exposure to a modality-specific stimulus and were never induced by stimulating a previously ineffective input channel. This short-term plasticity likely provides substantial benefits to the organism in dealing with ongoing and sequential events that take place at a given location in space and may reflect the ability of multisensory superior colliculus neurons to rapidly alter their response properties to accommodate to changes in environmental challenges and event probabilities.
Url:
DOI: 10.1152/jn.00739.2012
PubMed: 23114212
PubMed Central: 3545460
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001424
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :001424
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :001651
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :002315
Links to Exploration step
PMC:3545460Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Multisensory plasticity in adulthood: cross-modal experience enhances neuronal excitability and exposes silent inputs</title><author><name sortKey="Yu, Liping" sort="Yu, Liping" uniqKey="Yu L" first="Liping" last="Yu">Liping Yu</name></author><author><name sortKey="Rowland, Benjamin A" sort="Rowland, Benjamin A" uniqKey="Rowland B" first="Benjamin A." last="Rowland">Benjamin A. Rowland</name></author><author><name sortKey="Xu, Jinghong" sort="Xu, Jinghong" uniqKey="Xu J" first="Jinghong" last="Xu">Jinghong Xu</name></author><author><name sortKey="Stein, Barry E" sort="Stein, Barry E" uniqKey="Stein B" first="Barry E." last="Stein">Barry E. Stein</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23114212</idno><idno type="pmc">3545460</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545460</idno><idno type="RBID">PMC:3545460</idno><idno type="doi">10.1152/jn.00739.2012</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">001424</idno><idno type="wicri:Area/Pmc/Curation">001424</idno><idno type="wicri:Area/Pmc/Checkpoint">001651</idno><idno type="wicri:Area/Ncbi/Merge">002315</idno><idno type="wicri:Area/Ncbi/Curation">002315</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Multisensory plasticity in adulthood: cross-modal experience enhances neuronal excitability and exposes silent inputs</title><author><name sortKey="Yu, Liping" sort="Yu, Liping" uniqKey="Yu L" first="Liping" last="Yu">Liping Yu</name></author><author><name sortKey="Rowland, Benjamin A" sort="Rowland, Benjamin A" uniqKey="Rowland B" first="Benjamin A." last="Rowland">Benjamin A. Rowland</name></author><author><name sortKey="Xu, Jinghong" sort="Xu, Jinghong" uniqKey="Xu J" first="Jinghong" last="Xu">Jinghong Xu</name></author><author><name sortKey="Stein, Barry E" sort="Stein, Barry E" uniqKey="Stein B" first="Barry E." last="Stein">Barry E. Stein</name></author></analytic><series><title level="j">Journal of Neurophysiology</title><idno type="ISSN">0022-3077</idno><idno type="eISSN">1522-1598</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Multisensory superior colliculus neurons in cats were found to retain substantial plasticity to short-term, site-specific experience with cross-modal stimuli well into adulthood. Following cross-modal exposure trials, these neurons substantially increased their sensitivity to the cross-modal stimulus configuration as well as to its individual component stimuli. In many cases, the exposure experience also revealed a previously ineffective or “silent” input channel, rendering it overtly responsive. These experience-induced changes required relatively few exposure trials and could be retained for more than 1 h. However, their induction was generally restricted to experience with cross-modal stimuli. Only rarely were they induced by exposure to a modality-specific stimulus and were never induced by stimulating a previously ineffective input channel. This short-term plasticity likely provides substantial benefits to the organism in dealing with ongoing and sequential events that take place at a given location in space and may reflect the ability of multisensory superior colliculus neurons to rapidly alter their response properties to accommodate to changes in environmental challenges and event probabilities.</p></div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002315 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 002315 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= HapticV1
|flux= Ncbi
|étape= Curation
|type= RBID
|clé= PMC:3545460
|texte= Multisensory plasticity in adulthood: cross-modal experience enhances neuronal excitability and exposes silent inputs
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:23114212" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \
| NlmPubMed2Wicri -a HapticV1
| This area was generated with Dilib version V0.6.23. |  |