Processing of tactile information by the hippocampus
Identifieur interne : 000C79 ( Ncbi/Curation ); précédent : 000C78; suivant : 000C80Processing of tactile information by the hippocampus
Auteurs : Antonio Pereira [Brésil] ; Sidarta Ribeiro [Brésil] ; Michael Wiest ; Leonardo C. Moore ; Janaina Pantoja ; Shih-Chieh Lin ; Miguel A. L. Nicolelis [Brésil, États-Unis, Suisse]Source :
- Proceedings of the National Academy of Sciences of the United States of America [ 0027-8424 ] ; 2007.
Abstract
The ability to detect unusual events occurring in the environment is essential for survival. Several studies have pointed to the hippocampus as a key brain structure in novelty detection, a claim substantiated by its wide access to sensory information through the entorhinal cortex and also distinct aspects of its intrinsic circuitry. Novelty detection is implemented by an associative match–mismatch algorithm involving the CA1 and CA3 hippocampal subfields that compares the stream of sensory inputs received by CA1 to the stored representation of spatiotemporal sequences in CA3. In some rodents, including the rat, the highly sensitive facial whiskers are responsible for providing accurate tactile information about nearby objects. Surprisingly, however, not much is known about how inputs from the whiskers reach CA1 and how they are processed therein. Using concurrent multielectrode neuronal recordings and chemical inactivation in behaving rats, we show that trigeminal inputs from the whiskers reach the CA1 region through thalamic and cortical relays associated with discriminative touch. Ensembles of hippocampal neurons also carry precise information about stimulus identity when recorded during performance in an aperture-discrimination task using the whiskers. We also found broad similarities between tactile responses of trigeminal stations and the hippocampus during different vigilance states (wake and sleep). Taken together, our results show that tactile information associated with fine whisker discrimination is readily available to the hippocampus for dynamic updating of spatial maps.
Url:
DOI: 10.1073/pnas.0708611104
PubMed: 17989221
PubMed Central: 2084335
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001546
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :001546
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :002433
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000C79
Links to Exploration step
PMC:2084335Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Processing of tactile information by the hippocampus</title>
<author><name sortKey="Pereira, Antonio" sort="Pereira, Antonio" uniqKey="Pereira A" first="Antonio" last="Pereira">Antonio Pereira</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">*Departamento de Fisiologia, Universidade Federal do Pará, PA 66075-900, Belém, Brazil;</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>*Departamento de Fisiologia, Universidade Federal do Pará, PA 66075-900, Belém</wicri:regionArea>
<wicri:noRegion>Belém</wicri:noRegion>
</affiliation>
<affiliation><nlm:aff id="aff2">Department of Neurobiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ribeiro, Sidarta" sort="Ribeiro, Sidarta" uniqKey="Ribeiro S" first="Sidarta" last="Ribeiro">Sidarta Ribeiro</name>
<affiliation wicri:level="1"><nlm:aff id="aff6">Edmond and Lily Safra International Institute of Neuroscience of Natal, RN 59066-060, Natal, Brazil;</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Edmond and Lily Safra International Institute of Neuroscience of Natal, RN 59066-060, Natal</wicri:regionArea>
<wicri:noRegion>Natal</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff wicri:cut="; and" id="aff7">Departamento de Fisiologia, Universidade Federal do Rio Grande do Norte, RN 59072-970, Natal, Brazil</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Fisiologia, Universidade Federal do Rio Grande do Norte, RN 59072-970, Natal</wicri:regionArea>
<wicri:noRegion>Natal</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wiest, Michael" sort="Wiest, Michael" uniqKey="Wiest M" first="Michael" last="Wiest">Michael Wiest</name>
<affiliation><nlm:aff id="aff2">Department of Neurobiology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff3">Center for Neuroengineering,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Moore, Leonardo C" sort="Moore, Leonardo C" uniqKey="Moore L" first="Leonardo C." last="Moore">Leonardo C. Moore</name>
<affiliation><nlm:aff id="aff2">Department of Neurobiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pantoja, Janaina" sort="Pantoja, Janaina" uniqKey="Pantoja J" first="Janaina" last="Pantoja">Janaina Pantoja</name>
<affiliation><nlm:aff id="aff2">Department of Neurobiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lin, Shih Chieh" sort="Lin, Shih Chieh" uniqKey="Lin S" first="Shih-Chieh" last="Lin">Shih-Chieh Lin</name>
<affiliation><nlm:aff id="aff2">Department of Neurobiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nicolelis, Miguel A L" sort="Nicolelis, Miguel A L" uniqKey="Nicolelis M" first="Miguel A. L." last="Nicolelis">Miguel A. L. Nicolelis</name>
<affiliation><nlm:aff id="aff2">Department of Neurobiology,</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff6">Edmond and Lily Safra International Institute of Neuroscience of Natal, RN 59066-060, Natal, Brazil;</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Edmond and Lily Safra International Institute of Neuroscience of Natal, RN 59066-060, Natal</wicri:regionArea>
<wicri:noRegion>Natal</wicri:noRegion>
</affiliation>
<affiliation><nlm:aff id="aff3">Center for Neuroengineering,</nlm:aff>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff5">**Department of Cognitive and Brain Sciences, Duke University, Durham, NC 27710;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
<wicri:cityArea>**Department of Cognitive and Brain Sciences, Duke University, Durham</wicri:cityArea>
</affiliation>
<affiliation><nlm:aff wicri:cut=", and" id="aff4">Department of Biomedical Engineering</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff8">Laboratory of Neural Ensemble Technology, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Laboratory of Neural Ensemble Technology, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne</wicri:regionArea>
<wicri:noRegion>CH-1015 Lausanne</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">17989221</idno>
<idno type="pmc">2084335</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2084335</idno>
<idno type="RBID">PMC:2084335</idno>
<idno type="doi">10.1073/pnas.0708611104</idno>
<date when="2007">2007</date>
<idno type="wicri:Area/Pmc/Corpus">001546</idno>
<idno type="wicri:Area/Pmc/Curation">001546</idno>
<idno type="wicri:Area/Pmc/Checkpoint">002433</idno>
<idno type="wicri:Area/Ncbi/Merge">000C79</idno>
<idno type="wicri:Area/Ncbi/Curation">000C79</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Processing of tactile information by the hippocampus</title>
<author><name sortKey="Pereira, Antonio" sort="Pereira, Antonio" uniqKey="Pereira A" first="Antonio" last="Pereira">Antonio Pereira</name>
<affiliation wicri:level="1"><nlm:aff id="aff1">*Departamento de Fisiologia, Universidade Federal do Pará, PA 66075-900, Belém, Brazil;</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>*Departamento de Fisiologia, Universidade Federal do Pará, PA 66075-900, Belém</wicri:regionArea>
<wicri:noRegion>Belém</wicri:noRegion>
</affiliation>
<affiliation><nlm:aff id="aff2">Department of Neurobiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ribeiro, Sidarta" sort="Ribeiro, Sidarta" uniqKey="Ribeiro S" first="Sidarta" last="Ribeiro">Sidarta Ribeiro</name>
<affiliation wicri:level="1"><nlm:aff id="aff6">Edmond and Lily Safra International Institute of Neuroscience of Natal, RN 59066-060, Natal, Brazil;</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Edmond and Lily Safra International Institute of Neuroscience of Natal, RN 59066-060, Natal</wicri:regionArea>
<wicri:noRegion>Natal</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff wicri:cut="; and" id="aff7">Departamento de Fisiologia, Universidade Federal do Rio Grande do Norte, RN 59072-970, Natal, Brazil</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Fisiologia, Universidade Federal do Rio Grande do Norte, RN 59072-970, Natal</wicri:regionArea>
<wicri:noRegion>Natal</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wiest, Michael" sort="Wiest, Michael" uniqKey="Wiest M" first="Michael" last="Wiest">Michael Wiest</name>
<affiliation><nlm:aff id="aff2">Department of Neurobiology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff3">Center for Neuroengineering,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Moore, Leonardo C" sort="Moore, Leonardo C" uniqKey="Moore L" first="Leonardo C." last="Moore">Leonardo C. Moore</name>
<affiliation><nlm:aff id="aff2">Department of Neurobiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Pantoja, Janaina" sort="Pantoja, Janaina" uniqKey="Pantoja J" first="Janaina" last="Pantoja">Janaina Pantoja</name>
<affiliation><nlm:aff id="aff2">Department of Neurobiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lin, Shih Chieh" sort="Lin, Shih Chieh" uniqKey="Lin S" first="Shih-Chieh" last="Lin">Shih-Chieh Lin</name>
<affiliation><nlm:aff id="aff2">Department of Neurobiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nicolelis, Miguel A L" sort="Nicolelis, Miguel A L" uniqKey="Nicolelis M" first="Miguel A. L." last="Nicolelis">Miguel A. L. Nicolelis</name>
<affiliation><nlm:aff id="aff2">Department of Neurobiology,</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff6">Edmond and Lily Safra International Institute of Neuroscience of Natal, RN 59066-060, Natal, Brazil;</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Edmond and Lily Safra International Institute of Neuroscience of Natal, RN 59066-060, Natal</wicri:regionArea>
<wicri:noRegion>Natal</wicri:noRegion>
</affiliation>
<affiliation><nlm:aff id="aff3">Center for Neuroengineering,</nlm:aff>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff5">**Department of Cognitive and Brain Sciences, Duke University, Durham, NC 27710;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
<wicri:cityArea>**Department of Cognitive and Brain Sciences, Duke University, Durham</wicri:cityArea>
</affiliation>
<affiliation><nlm:aff wicri:cut=", and" id="aff4">Department of Biomedical Engineering</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff8">Laboratory of Neural Ensemble Technology, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Laboratory of Neural Ensemble Technology, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne</wicri:regionArea>
<wicri:noRegion>CH-1015 Lausanne</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Proceedings of the National Academy of Sciences of the United States of America</title>
<idno type="ISSN">0027-8424</idno>
<idno type="eISSN">1091-6490</idno>
<imprint><date when="2007">2007</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>The ability to detect unusual events occurring in the environment is essential for survival. Several studies have pointed to the hippocampus as a key brain structure in novelty detection, a claim substantiated by its wide access to sensory information through the entorhinal cortex and also distinct aspects of its intrinsic circuitry. Novelty detection is implemented by an associative match–mismatch algorithm involving the CA1 and CA3 hippocampal subfields that compares the stream of sensory inputs received by CA1 to the stored representation of spatiotemporal sequences in CA3. In some rodents, including the rat, the highly sensitive facial whiskers are responsible for providing accurate tactile information about nearby objects. Surprisingly, however, not much is known about how inputs from the whiskers reach CA1 and how they are processed therein. Using concurrent multielectrode neuronal recordings and chemical inactivation in behaving rats, we show that trigeminal inputs from the whiskers reach the CA1 region through thalamic and cortical relays associated with discriminative touch. Ensembles of hippocampal neurons also carry precise information about stimulus identity when recorded during performance in an aperture-discrimination task using the whiskers. We also found broad similarities between tactile responses of trigeminal stations and the hippocampus during different vigilance states (wake and sleep). Taken together, our results show that tactile information associated with fine whisker discrimination is readily available to the hippocampus for dynamic updating of spatial maps.</p>
</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000C79 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 000C79 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Ticri/CIDE |area= HapticV1 |flux= Ncbi |étape= Curation |type= RBID |clé= PMC:2084335 |texte= Processing of tactile information by the hippocampus }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:17989221" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a HapticV1
![]() | This area was generated with Dilib version V0.6.23. | ![]() |