The Lens Capsule
Identifieur interne : 000F14 ( Ncbi/Checkpoint ); précédent : 000F13; suivant : 000F15The Lens Capsule
Auteurs : Brian P. Danysh ; Melinda K. DuncanSource :
- Experimental eye research [ 0014-4835 ] ; 2008.
Abstract
The lens capsule is a modified basement membrane that completely surrounds the ocular lens. It is known that this extracellular matrix is important for both the structure and biomechanics of the lens in addition to providing informational cues to maintain lens cell phenotype. This review covers the development and structure of the lens capsule, lens diseases associated with mutations in extracellular matrix genes and the role of the capsule in lens function including those proposed for visual accommodation, selective permeability to infectious agents, and cell signaling.
Url:
DOI: 10.1016/j.exer.2008.08.002
PubMed: 18773892
PubMed Central: 2674021
Affiliations:
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PMC:2674021Le document en format XML
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<front><div type="abstract" xml:lang="en"><p id="P1">The lens capsule is a modified basement membrane that completely surrounds the ocular lens. It is known that this extracellular matrix is important for both the structure and biomechanics of the lens in addition to providing informational cues to maintain lens cell phenotype. This review covers the development and structure of the lens capsule, lens diseases associated with mutations in extracellular matrix genes and the role of the capsule in lens function including those proposed for visual accommodation, selective permeability to infectious agents, and cell signaling.</p>
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<name sortKey="Duncan, Melinda K" sort="Duncan, Melinda K" uniqKey="Duncan M" first="Melinda K." last="Duncan">Melinda K. Duncan</name>
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