Influence of three‐piece and single‐piece designs of two sharp‐edge optic hydrophobic acrylic intraocular lenses on the prevention of posterior capsule opacification: a prospective, randomised, long‐term clinical trial
Identifieur interne : 000A33 ( Ncbi/Checkpoint ); précédent : 000A32; suivant : 000A34Influence of three‐piece and single‐piece designs of two sharp‐edge optic hydrophobic acrylic intraocular lenses on the prevention of posterior capsule opacification: a prospective, randomised, long‐term clinical trial
Auteurs : Reda Zemaitiene ; Vytautas Jasinskas ; Gerd U. AuffarthSource :
- The British Journal of Ophthalmology [ 0007-1161 ] ; 2006.
English descriptors
- KwdEn :
- Aged, Cataract (physiopathology), Cataract Extraction (instrumentation), Humans, Hydrophobic and Hydrophilic Interactions, Lens Capsule, Crystalline, Lenses, Intraocular, Postoperative Complications (prevention & control), Prospective Studies, Prosthesis Design, Treatment Outcome, Visual Acuity (physiology).
- MESH :
- instrumentation : Cataract Extraction.
- physiology : Visual Acuity.
- physiopathology : Cataract.
- prevention & control : Postoperative Complications.
- Aged, Humans, Hydrophobic and Hydrophilic Interactions, Lens Capsule, Crystalline, Lenses, Intraocular, Prospective Studies, Prosthesis Design, Treatment Outcome.
Abstract
Posterior capsule opacification (PCO) is still a major long‐term complication of modern cataract surgery. We evaluated the impact of sharp‐edged intraocular lenses (IOLs) with different haptic designs made from the same hydrophobic acrylic material on posterior and anterior lens capsule opacification.
Eye clinic of Kaunas University of Medicine, Lithuania. Prospective randomised clinical study.
Seventy‐four eyes of 74 patients scheduled for cataract surgery were included in a prospective randomised clinical study. Thirty‐seven eyes of 37 patients received a three‐piece acrylic hydrophobic (AcrySof, MA3OBA, Alcon) IOL; and thirty‐seven eyes of 37 patients received a one‐piece acrylic hydrophobic (AcrySof, SA3OAL, Alcon) IOL. Visual acuity, anterior capsule opacification (ACO), capsular folds, capsulorrhexis/optic overlapping and posterior capsule opacification (PCO) were evaluated. ACO was assessed subjectively. PCO values in the entire IOL optic area and in the central 3 mm optic zone were assessed using a photographic image‐analysis system (EPCO2000). Follow‐ups were performed postoperatively at 1 day, 6 months, 1 year and 2 years.
There were no significant differences in best corrected visual acuity, grade of ACO and capsulorrhexis/optic overlapping between IOL types during the follow‐up period. Patients in the one‐piece acrylic hydrophobic IOL group more frequently presented with capsular folds behind the IOL optic area than those in the three‐piece IOL group. In the three‐piece acrylic hydrophobic IOL group, PCO values (mean (SD)) of the entire IOL optic area were significantly lower six months postoperative (three‐piece: 0.002 (0.009); one‐piece: 0.007 (0.017); p = 0.04), one year postoperative (three‐piece: 0.004 (0.016); one‐piece: 0.026 (0.041); p = 0.001) as well as one year postoperative in the central 3 mm optic zone (three‐piece: 0.000 (0.0002); one‐piece: 0.019 (0.049); p = 0.001). However, two years postoperative, the PCO values of the groups did not show significant differences (entire IOL optic area: three‐piece, 0.136 (0.223); one‐piece, 0.154 (0.190); p = 0.18; central zone: three‐piece, 0.023 (0.065); one‐piece: 0.020 (0.039); p = 0.44).
The 2 year follow‐up after cataract surgery showed no significant difference in ACO and PCO development between three‐piece and one‐piece acrylic hydrophobic intraocular lenses.
Url:
DOI: 10.1136/bjo.2006.103648
PubMed: 17124239
PubMed Central: 1954737
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Influence of three‐piece and single‐piece designs of two sharp‐edge optic hydrophobic acrylic intraocular lenses on the prevention of posterior capsule opacification: a prospective, randomised, long‐term clinical trial</title><author><name sortKey="Zemaitiene, Reda" sort="Zemaitiene, Reda" uniqKey="Zemaitiene R" first="Reda" last="Zemaitiene">Reda Zemaitiene</name></author><author><name sortKey="Jasinskas, Vytautas" sort="Jasinskas, Vytautas" uniqKey="Jasinskas V" first="Vytautas" last="Jasinskas">Vytautas Jasinskas</name></author><author><name sortKey="Auffarth, Gerd U" sort="Auffarth, Gerd U" uniqKey="Auffarth G" first="Gerd U" last="Auffarth">Gerd U. Auffarth</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">17124239</idno><idno type="pmc">1954737</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1954737</idno><idno type="RBID">PMC:1954737</idno><idno type="doi">10.1136/bjo.2006.103648</idno><date when="2006">2006</date><idno type="wicri:Area/Pmc/Corpus">000A51</idno><idno type="wicri:Area/Pmc/Curation">000A51</idno><idno type="wicri:Area/Pmc/Checkpoint">002544</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">001726</idno><idno type="wicri:Area/PubMed/Curation">001726</idno><idno type="wicri:Area/PubMed/Checkpoint">001419</idno><idno type="wicri:Area/Ncbi/Merge">000A33</idno><idno type="wicri:Area/Ncbi/Curation">000A33</idno><idno type="wicri:Area/Ncbi/Checkpoint">000A33</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Influence of three‐piece and single‐piece designs of two sharp‐edge optic hydrophobic acrylic intraocular lenses on the prevention of posterior capsule opacification: a prospective, randomised, long‐term clinical trial</title><author><name sortKey="Zemaitiene, Reda" sort="Zemaitiene, Reda" uniqKey="Zemaitiene R" first="Reda" last="Zemaitiene">Reda Zemaitiene</name></author><author><name sortKey="Jasinskas, Vytautas" sort="Jasinskas, Vytautas" uniqKey="Jasinskas V" first="Vytautas" last="Jasinskas">Vytautas Jasinskas</name></author><author><name sortKey="Auffarth, Gerd U" sort="Auffarth, Gerd U" uniqKey="Auffarth G" first="Gerd U" last="Auffarth">Gerd U. Auffarth</name></author></analytic><series><title level="j">The British Journal of Ophthalmology</title><idno type="ISSN">0007-1161</idno><idno type="eISSN">1468-2079</idno><imprint><date when="2006">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Cataract (physiopathology)</term><term>Cataract Extraction (instrumentation)</term><term>Humans</term><term>Hydrophobic and Hydrophilic Interactions</term><term>Lens Capsule, Crystalline</term><term>Lenses, Intraocular</term><term>Postoperative Complications (prevention & control)</term><term>Prospective Studies</term><term>Prosthesis Design</term><term>Treatment Outcome</term><term>Visual Acuity (physiology)</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Cataract Extraction</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Visual Acuity</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Cataract</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Postoperative Complications</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Humans</term><term>Hydrophobic and Hydrophilic Interactions</term><term>Lens Capsule, Crystalline</term><term>Lenses, Intraocular</term><term>Prospective Studies</term><term>Prosthesis Design</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>Posterior capsule opacification (PCO) is still a major long‐term complication of modern cataract surgery. We evaluated the impact of sharp‐edged intraocular lenses (IOLs) with different haptic designs made from the same hydrophobic acrylic material on posterior and anterior lens capsule opacification.</p></sec><sec><title>Setting</title><p>Eye clinic of Kaunas University of Medicine, Lithuania. Prospective randomised clinical study.</p></sec><sec><title>Methods</title><p>Seventy‐four eyes of 74 patients scheduled for cataract surgery were included in a prospective randomised clinical study. Thirty‐seven eyes of 37 patients received a three‐piece acrylic hydrophobic (AcrySof, MA3OBA, Alcon) IOL; and thirty‐seven eyes of 37 patients received a one‐piece acrylic hydrophobic (AcrySof, SA3OAL, Alcon) IOL. Visual acuity, anterior capsule opacification (ACO), capsular folds, capsulorrhexis/optic overlapping and posterior capsule opacification (PCO) were evaluated. ACO was assessed subjectively. PCO values in the entire IOL optic area and in the central 3 mm optic zone were assessed using a photographic image‐analysis system (EPCO2000). Follow‐ups were performed postoperatively at 1 day, 6 months, 1 year and 2 years.</p></sec><sec><title>Results</title><p>There were no significant differences in best corrected visual acuity, grade of ACO and capsulorrhexis/optic overlapping between IOL types during the follow‐up period. Patients in the one‐piece acrylic hydrophobic IOL group more frequently presented with capsular folds behind the IOL optic area than those in the three‐piece IOL group. In the three‐piece acrylic hydrophobic IOL group, PCO values (mean (SD)) of the entire IOL optic area were significantly lower six months postoperative (three‐piece: 0.002 (0.009); one‐piece: 0.007 (0.017); p = 0.04), one year postoperative (three‐piece: 0.004 (0.016); one‐piece: 0.026 (0.041); p = 0.001) as well as one year postoperative in the central 3 mm optic zone (three‐piece: 0.000 (0.0002); one‐piece: 0.019 (0.049); p = 0.001). However, two years postoperative, the PCO values of the groups did not show significant differences (entire IOL optic area: three‐piece, 0.136 (0.223); one‐piece, 0.154 (0.190); p = 0.18; central zone: three‐piece, 0.023 (0.065); one‐piece: 0.020 (0.039); p = 0.44).</p></sec><sec><title>Conclusion</title><p>The 2 year follow‐up after cataract surgery showed no significant difference in ACO and PCO development between three‐piece and one‐piece acrylic hydrophobic intraocular lenses.</p></sec></div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Auffarth, Gerd U" sort="Auffarth, Gerd U" uniqKey="Auffarth G" first="Gerd U" last="Auffarth">Gerd U. Auffarth</name><name sortKey="Jasinskas, Vytautas" sort="Jasinskas, Vytautas" uniqKey="Jasinskas V" first="Vytautas" last="Jasinskas">Vytautas Jasinskas</name><name sortKey="Zemaitiene, Reda" sort="Zemaitiene, Reda" uniqKey="Zemaitiene R" first="Reda" last="Zemaitiene">Reda Zemaitiene</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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