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Is impaired set-shifting an endophenotype of anorexia nervosa?

Identifieur interne : 006527 ( Main/Merge ); précédent : 006526; suivant : 006528

Is impaired set-shifting an endophenotype of anorexia nervosa?

Auteurs : Joanna Holliday [Royaume-Uni] ; Kate Tchanturia ; Sabine Landau ; David Collier ; Janet Treasure

Source :

RBID : pubmed:16330590

English descriptors

Abstract

Set-shifting difficulties have been reported in subjects with anorexia nervosa and appear to persist after recovery; therefore, they may be endophenotypic traits. The goals of this study were to investigate whether set-shifting difficulties are familial by examining discordant sister-pairs in comparison with healthy unrelated women and to replicate, with a broader battery, the lack of influence of an acute illness state on neuropsychological performance.

DOI: 10.1176/appi.ajp.162.12.2269
PubMed: 16330590

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pubmed:16330590

Le document en format XML

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<nlm:affiliation>Division of Psychological Medicine, Institute of Psychiatry, King's College London, UK. joanna.holliday@hmc.ox.ac.uk</nlm:affiliation>
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<div type="abstract" xml:lang="en">Set-shifting difficulties have been reported in subjects with anorexia nervosa and appear to persist after recovery; therefore, they may be endophenotypic traits. The goals of this study were to investigate whether set-shifting difficulties are familial by examining discordant sister-pairs in comparison with healthy unrelated women and to replicate, with a broader battery, the lack of influence of an acute illness state on neuropsychological performance.</div>
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