Is impaired set-shifting an endophenotype of anorexia nervosa?
Identifieur interne : 006527 ( Main/Merge ); précédent : 006526; suivant : 006528Is impaired set-shifting an endophenotype of anorexia nervosa?
Auteurs : Joanna Holliday [Royaume-Uni] ; Kate Tchanturia ; Sabine Landau ; David Collier ; Janet TreasureSource :
- The American journal of psychiatry [ 0002-953X ] ; 2005.
English descriptors
- KwdEn :
- Adult, Age Factors, Age of Onset, Analysis of Variance, Anorexia Nervosa (diagnosis), Anorexia Nervosa (epidemiology), Anorexia Nervosa (genetics), Body Mass Index, Cognition Disorders (diagnosis), Cognition Disorders (epidemiology), Cognition Disorders (genetics), Comorbidity, Female, Genetic Markers, Humans, Intelligence Tests, Neuropsychological Tests (statistics & numerical data), Personality Inventory, Phenotype, Prefrontal Cortex (physiology), Psychomotor Performance (physiology), Siblings (psychology), Trail Making Test (statistics & numerical data).
- MESH :
- chemical : Genetic Markers.
- diagnosis : Anorexia Nervosa, Cognition Disorders.
- epidemiology : Anorexia Nervosa, Cognition Disorders.
- genetics : Anorexia Nervosa, Cognition Disorders.
- physiology : Prefrontal Cortex, Psychomotor Performance.
- psychology : Siblings.
- statistics & numerical data : Neuropsychological Tests, Trail Making Test.
- Adult, Age Factors, Age of Onset, Analysis of Variance, Body Mass Index, Comorbidity, Female, Humans, Intelligence Tests, Personality Inventory, Phenotype.
Abstract
Set-shifting difficulties have been reported in subjects with anorexia nervosa and appear to persist after recovery; therefore, they may be endophenotypic traits. The goals of this study were to investigate whether set-shifting difficulties are familial by examining discordant sister-pairs in comparison with healthy unrelated women and to replicate, with a broader battery, the lack of influence of an acute illness state on neuropsychological performance.
DOI: 10.1176/appi.ajp.162.12.2269
PubMed: 16330590
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pubmed:16330590Le document en format XML
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<author><name sortKey="Tchanturia, Kate" sort="Tchanturia, Kate" uniqKey="Tchanturia K" first="Kate" last="Tchanturia">Kate Tchanturia</name>
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<series><title level="j">The American journal of psychiatry</title>
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<term>Psychomotor Performance (physiology)</term>
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<term>Cognition Disorders</term>
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<term>Age of Onset</term>
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<term>Comorbidity</term>
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<front><div type="abstract" xml:lang="en">Set-shifting difficulties have been reported in subjects with anorexia nervosa and appear to persist after recovery; therefore, they may be endophenotypic traits. The goals of this study were to investigate whether set-shifting difficulties are familial by examining discordant sister-pairs in comparison with healthy unrelated women and to replicate, with a broader battery, the lack of influence of an acute illness state on neuropsychological performance.</div>
</front>
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