Peripheral Somatosensation: A Touch of Genetics
Identifieur interne : 002A57 ( Main/Merge ); précédent : 002A56; suivant : 002A58Peripheral Somatosensation: A Touch of Genetics
Auteurs : Erin G. Reed-Geaghan [États-Unis] ; Stephen M. Maricich [États-Unis]Source :
- Current opinion in genetics & development [ 0959-437X ] ; 2011.
Abstract
The somatosensory system processes information that organisms “feel”: joint position, muscle stretch, pain, pressure, temperature, and touch. The system is composed of a diverse array of peripheral nerve endings specialized to detect these sensory modalities. Several recent discoveries have shed light on the genetic pathways that control specification and differentiation of these neurons, how they accurately innervate their central and peripheral targets, and the molecules that enable them to detect mechanical stimuli. Here, we review the cadre of genes that control these processes, focusing on mechanosensitive neurons and support cells of the skin that mediate different aspects of the sense of touch.
Url:
DOI: 10.1016/j.gde.2010.12.009
PubMed: 21277195
PubMed Central: 3097266
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 001046
- to stream Pmc, to step Curation: 001046
- to stream Pmc, to step Checkpoint: 001A36
- to stream Ncbi, to step Merge: 001863
- to stream Ncbi, to step Curation: 001863
- to stream Ncbi, to step Checkpoint: 001863
Links to Exploration step
PMC:3097266Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Peripheral Somatosensation: A Touch of Genetics</title><author><name sortKey="Reed Geaghan, Erin G" sort="Reed Geaghan, Erin G" uniqKey="Reed Geaghan E" first="Erin G." last="Reed-Geaghan">Erin G. Reed-Geaghan</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Pediatrics, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland, OH 44106</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea> Department of Pediatrics, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland</wicri:cityArea></affiliation></author><author><name sortKey="Maricich, Stephen M" sort="Maricich, Stephen M" uniqKey="Maricich S" first="Stephen M." last="Maricich">Stephen M. Maricich</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Pediatrics, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland, OH 44106</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea> Department of Pediatrics, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Department of Neurosciences, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland, OH 44106</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea> Department of Neurosciences, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A3"> Department of Otolaryngology, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland, OH 44106</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea> Department of Otolaryngology, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21277195</idno><idno type="pmc">3097266</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097266</idno><idno type="RBID">PMC:3097266</idno><idno type="doi">10.1016/j.gde.2010.12.009</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">001046</idno><idno type="wicri:Area/Pmc/Curation">001046</idno><idno type="wicri:Area/Pmc/Checkpoint">001A36</idno><idno type="wicri:Area/Ncbi/Merge">001863</idno><idno type="wicri:Area/Ncbi/Curation">001863</idno><idno type="wicri:Area/Ncbi/Checkpoint">001863</idno><idno type="wicri:doubleKey">0959-437X:2011:Reed Geaghan E:peripheral:somatosensation:a</idno><idno type="wicri:Area/Main/Merge">002A57</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Peripheral Somatosensation: A Touch of Genetics</title><author><name sortKey="Reed Geaghan, Erin G" sort="Reed Geaghan, Erin G" uniqKey="Reed Geaghan E" first="Erin G." last="Reed-Geaghan">Erin G. Reed-Geaghan</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Pediatrics, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland, OH 44106</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea> Department of Pediatrics, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland</wicri:cityArea></affiliation></author><author><name sortKey="Maricich, Stephen M" sort="Maricich, Stephen M" uniqKey="Maricich S" first="Stephen M." last="Maricich">Stephen M. Maricich</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Pediatrics, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland, OH 44106</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea> Department of Pediatrics, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Department of Neurosciences, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland, OH 44106</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea> Department of Neurosciences, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A3"> Department of Otolaryngology, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland, OH 44106</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea> Department of Otolaryngology, Case Western Reserve University, School of Medicine, 10900 Euclid Avenue, Cleveland</wicri:cityArea></affiliation></author></analytic><series><title level="j">Current opinion in genetics & development</title><idno type="ISSN">0959-437X</idno><idno type="eISSN">1879-0380</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Summary</title><p id="P2">The somatosensory system processes information that organisms “feel”: joint position, muscle stretch, pain, pressure, temperature, and touch. The system is composed of a diverse array of peripheral nerve endings specialized to detect these sensory modalities. Several recent discoveries have shed light on the genetic pathways that control specification and differentiation of these neurons, how they accurately innervate their central and peripheral targets, and the molecules that enable them to detect mechanical stimuli. Here, we review the cadre of genes that control these processes, focusing on mechanosensitive neurons and support cells of the skin that mediate different aspects of the sense of touch.</p></div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002A57 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 002A57 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= HapticV1
|flux= Main
|étape= Merge
|type= RBID
|clé= PMC:3097266
|texte= Peripheral Somatosensation: A Touch of Genetics
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i -Sk "pubmed:21277195" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd \
| NlmPubMed2Wicri -a HapticV1
| This area was generated with Dilib version V0.6.23. |  |