Long-term results and biocompatibility of heparin-surface-modified intraocular lenses.
Identifieur interne : 009327 ( Main/Exploration ); précédent : 009326; suivant : 009328Long-term results and biocompatibility of heparin-surface-modified intraocular lenses.
Auteurs : M. Amon [Autriche] ; R. MenapaceSource :
- Journal of cataract and refractive surgery [ 0886-3350 ] ; 1993.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Biocompatible Materials, Cataract Extraction, Female, Fibroblasts (pathology), Foreign-Body Reaction (pathology), Giant Cells (pathology), Heparin, Humans, Lenses, Intraocular, Longitudinal Studies, Male, Methylmethacrylate, Methylmethacrylates, Middle Aged, Prospective Studies, Prosthesis Design, Treatment Outcome, Visual Acuity.
- MESH :
- chemical : Biocompatible Materials, Heparin, Methylmethacrylate, Methylmethacrylates.
- pathology : Fibroblasts, Foreign-Body Reaction, Giant Cells.
- Adult, Aged, Aged, 80 and over, Cataract Extraction, Female, Humans, Lenses, Intraocular, Longitudinal Studies, Male, Middle Aged, Prospective Studies, Prosthesis Design, Treatment Outcome, Visual Acuity.
Abstract
A prospective in vivo study of 50 intraocular lenses was done to document the long-term results and biocompatibility of heparin-surface-modified poly(methyl methacrylate) posterior chamber lenses. Continuous curvilinear capsulorhexis and phacoemulsification were performed throughout and examinations were by slit-lamp and specular microscopy. Decentrations of more than 1 mm were seen in 4% of eyes. Stress folds from the haptic traction forces were detected in 16%. A posterior capsulotomy was performed in 10% because of fibrosis or Elschnig pearl formation. Fine fibers were found on the lens surface in 76%. During the first postoperative days only a moderate number of fibroblast-like cells was observed. Foreign-body giant cells were seen in 8%. All cases with foreign-body giant cells had posterior synechias. Visual performance and clinical results were comparable to those of other well-approved intraocular lenses. The low percentage of cellular reaction on the lens surface suggests good biocompatibility.
PubMed: 8487171
Affiliations:
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Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Long-term results and biocompatibility of heparin-surface-modified intraocular lenses.</title><author><name sortKey="Amon, M" sort="Amon, M" uniqKey="Amon M" first="M" last="Amon">M. Amon</name><affiliation wicri:level="3"><nlm:affiliation>1. Universität Augenklinik Wien, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>1. Universität Augenklinik Wien, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Menapace, R" sort="Menapace, R" uniqKey="Menapace R" first="R" last="Menapace">R. Menapace</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1993">1993</date><idno type="RBID">pubmed:8487171</idno><idno type="pmid">8487171</idno><idno type="wicri:Area/PubMed/Corpus">002168</idno><idno type="wicri:Area/PubMed/Curation">002168</idno><idno type="wicri:Area/PubMed/Checkpoint">001E87</idno><idno type="wicri:Area/Ncbi/Merge">004571</idno><idno type="wicri:Area/Ncbi/Curation">004571</idno><idno type="wicri:Area/Ncbi/Checkpoint">004571</idno><idno type="wicri:doubleKey">0886-3350:1993:Amon M:long:term:results</idno><idno type="wicri:Area/Main/Merge">009D16</idno><idno type="wicri:Area/Main/Curation">009327</idno><idno type="wicri:Area/Main/Exploration">009327</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Long-term results and biocompatibility of heparin-surface-modified intraocular lenses.</title><author><name sortKey="Amon, M" sort="Amon, M" uniqKey="Amon M" first="M" last="Amon">M. Amon</name><affiliation wicri:level="3"><nlm:affiliation>1. Universität Augenklinik Wien, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>1. Universität Augenklinik Wien, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Menapace, R" sort="Menapace, R" uniqKey="Menapace R" first="R" last="Menapace">R. Menapace</name></author></analytic><series><title level="j">Journal of cataract and refractive surgery</title><idno type="ISSN">0886-3350</idno><imprint><date when="1993" type="published">1993</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Biocompatible Materials</term><term>Cataract Extraction</term><term>Female</term><term>Fibroblasts (pathology)</term><term>Foreign-Body Reaction (pathology)</term><term>Giant Cells (pathology)</term><term>Heparin</term><term>Humans</term><term>Lenses, Intraocular</term><term>Longitudinal Studies</term><term>Male</term><term>Methylmethacrylate</term><term>Methylmethacrylates</term><term>Middle Aged</term><term>Prospective Studies</term><term>Prosthesis Design</term><term>Treatment Outcome</term><term>Visual Acuity</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Biocompatible Materials</term><term>Heparin</term><term>Methylmethacrylate</term><term>Methylmethacrylates</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Fibroblasts</term><term>Foreign-Body Reaction</term><term>Giant Cells</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Cataract Extraction</term><term>Female</term><term>Humans</term><term>Lenses, Intraocular</term><term>Longitudinal Studies</term><term>Male</term><term>Middle Aged</term><term>Prospective Studies</term><term>Prosthesis Design</term><term>Treatment Outcome</term><term>Visual Acuity</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A prospective in vivo study of 50 intraocular lenses was done to document the long-term results and biocompatibility of heparin-surface-modified poly(methyl methacrylate) posterior chamber lenses. Continuous curvilinear capsulorhexis and phacoemulsification were performed throughout and examinations were by slit-lamp and specular microscopy. Decentrations of more than 1 mm were seen in 4% of eyes. Stress folds from the haptic traction forces were detected in 16%. A posterior capsulotomy was performed in 10% because of fibrosis or Elschnig pearl formation. Fine fibers were found on the lens surface in 76%. During the first postoperative days only a moderate number of fibroblast-like cells was observed. Foreign-body giant cells were seen in 8%. All cases with foreign-body giant cells had posterior synechias. Visual performance and clinical results were comparable to those of other well-approved intraocular lenses. The low percentage of cellular reaction on the lens surface suggests good biocompatibility.</div></front></TEI><affiliations><list><country><li>Autriche</li></country><region><li>Vienne (Autriche)</li></region><settlement><li>Vienne (Autriche)</li></settlement></list><tree><noCountry><name sortKey="Menapace, R" sort="Menapace, R" uniqKey="Menapace R" first="R" last="Menapace">R. Menapace</name></noCountry><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Amon, M" sort="Amon, M" uniqKey="Amon M" first="M" last="Amon">M. Amon</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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