Long-term results and biocompatibility of heparin-surface-modified intraocular lenses.
Identifieur interne : 002168 ( PubMed/Corpus ); précédent : 002167; suivant : 002169Long-term results and biocompatibility of heparin-surface-modified intraocular lenses.
Auteurs : M. Amon ; R. MenapaceSource :
- Journal of cataract and refractive surgery [ 0886-3350 ] ; 1993.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Biocompatible Materials, Cataract Extraction, Female, Fibroblasts (pathology), Foreign-Body Reaction (pathology), Giant Cells (pathology), Heparin, Humans, Lenses, Intraocular, Longitudinal Studies, Male, Methylmethacrylate, Methylmethacrylates, Middle Aged, Prospective Studies, Prosthesis Design, Treatment Outcome, Visual Acuity.
- MESH :
- chemical : Biocompatible Materials, Heparin, Methylmethacrylate, Methylmethacrylates.
- pathology : Fibroblasts, Foreign-Body Reaction, Giant Cells.
- Adult, Aged, Aged, 80 and over, Cataract Extraction, Female, Humans, Lenses, Intraocular, Longitudinal Studies, Male, Middle Aged, Prospective Studies, Prosthesis Design, Treatment Outcome, Visual Acuity.
Abstract
A prospective in vivo study of 50 intraocular lenses was done to document the long-term results and biocompatibility of heparin-surface-modified poly(methyl methacrylate) posterior chamber lenses. Continuous curvilinear capsulorhexis and phacoemulsification were performed throughout and examinations were by slit-lamp and specular microscopy. Decentrations of more than 1 mm were seen in 4% of eyes. Stress folds from the haptic traction forces were detected in 16%. A posterior capsulotomy was performed in 10% because of fibrosis or Elschnig pearl formation. Fine fibers were found on the lens surface in 76%. During the first postoperative days only a moderate number of fibroblast-like cells was observed. Foreign-body giant cells were seen in 8%. All cases with foreign-body giant cells had posterior synechias. Visual performance and clinical results were comparable to those of other well-approved intraocular lenses. The low percentage of cellular reaction on the lens surface suggests good biocompatibility.
PubMed: 8487171
Links to Exploration step
pubmed:8487171Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Long-term results and biocompatibility of heparin-surface-modified intraocular lenses.</title><author><name sortKey="Amon, M" sort="Amon, M" uniqKey="Amon M" first="M" last="Amon">M. Amon</name><affiliation><nlm:affiliation>1. Universität Augenklinik Wien, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Menapace, R" sort="Menapace, R" uniqKey="Menapace R" first="R" last="Menapace">R. Menapace</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1993">1993</date><idno type="RBID">pubmed:8487171</idno><idno type="pmid">8487171</idno><idno type="wicri:Area/PubMed/Corpus">002168</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Long-term results and biocompatibility of heparin-surface-modified intraocular lenses.</title><author><name sortKey="Amon, M" sort="Amon, M" uniqKey="Amon M" first="M" last="Amon">M. Amon</name><affiliation><nlm:affiliation>1. Universität Augenklinik Wien, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Menapace, R" sort="Menapace, R" uniqKey="Menapace R" first="R" last="Menapace">R. Menapace</name></author></analytic><series><title level="j">Journal of cataract and refractive surgery</title><idno type="ISSN">0886-3350</idno><imprint><date when="1993" type="published">1993</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Biocompatible Materials</term><term>Cataract Extraction</term><term>Female</term><term>Fibroblasts (pathology)</term><term>Foreign-Body Reaction (pathology)</term><term>Giant Cells (pathology)</term><term>Heparin</term><term>Humans</term><term>Lenses, Intraocular</term><term>Longitudinal Studies</term><term>Male</term><term>Methylmethacrylate</term><term>Methylmethacrylates</term><term>Middle Aged</term><term>Prospective Studies</term><term>Prosthesis Design</term><term>Treatment Outcome</term><term>Visual Acuity</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Biocompatible Materials</term><term>Heparin</term><term>Methylmethacrylate</term><term>Methylmethacrylates</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Fibroblasts</term><term>Foreign-Body Reaction</term><term>Giant Cells</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Cataract Extraction</term><term>Female</term><term>Humans</term><term>Lenses, Intraocular</term><term>Longitudinal Studies</term><term>Male</term><term>Middle Aged</term><term>Prospective Studies</term><term>Prosthesis Design</term><term>Treatment Outcome</term><term>Visual Acuity</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A prospective in vivo study of 50 intraocular lenses was done to document the long-term results and biocompatibility of heparin-surface-modified poly(methyl methacrylate) posterior chamber lenses. Continuous curvilinear capsulorhexis and phacoemulsification were performed throughout and examinations were by slit-lamp and specular microscopy. Decentrations of more than 1 mm were seen in 4% of eyes. Stress folds from the haptic traction forces were detected in 16%. A posterior capsulotomy was performed in 10% because of fibrosis or Elschnig pearl formation. Fine fibers were found on the lens surface in 76%. During the first postoperative days only a moderate number of fibroblast-like cells was observed. Foreign-body giant cells were seen in 8%. All cases with foreign-body giant cells had posterior synechias. Visual performance and clinical results were comparable to those of other well-approved intraocular lenses. The low percentage of cellular reaction on the lens surface suggests good biocompatibility.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">8487171</PMID><DateCreated><Year>1993</Year><Month>06</Month><Day>07</Day></DateCreated><DateCompleted><Year>1993</Year><Month>06</Month><Day>07</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0886-3350</ISSN><JournalIssue CitedMedium="Print"><Volume>19</Volume><Issue>2</Issue><PubDate><Year>1993</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Journal of cataract and refractive surgery</Title><ISOAbbreviation>J Cataract Refract Surg</ISOAbbreviation></Journal><ArticleTitle>Long-term results and biocompatibility of heparin-surface-modified intraocular lenses.</ArticleTitle><Pagination><MedlinePgn>258-62</MedlinePgn></Pagination><Abstract><AbstractText>A prospective in vivo study of 50 intraocular lenses was done to document the long-term results and biocompatibility of heparin-surface-modified poly(methyl methacrylate) posterior chamber lenses. Continuous curvilinear capsulorhexis and phacoemulsification were performed throughout and examinations were by slit-lamp and specular microscopy. Decentrations of more than 1 mm were seen in 4% of eyes. Stress folds from the haptic traction forces were detected in 16%. A posterior capsulotomy was performed in 10% because of fibrosis or Elschnig pearl formation. Fine fibers were found on the lens surface in 76%. During the first postoperative days only a moderate number of fibroblast-like cells was observed. Foreign-body giant cells were seen in 8%. All cases with foreign-body giant cells had posterior synechias. Visual performance and clinical results were comparable to those of other well-approved intraocular lenses. The low percentage of cellular reaction on the lens surface suggests good biocompatibility.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Amon</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>1. Universität Augenklinik Wien, Vienna, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Menapace</LastName><ForeName>R</ForeName><Initials>R</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>UNITED STATES</Country><MedlineTA>J Cataract Refract Surg</MedlineTA><NlmUniqueID>8604171</NlmUniqueID><ISSNLinking>0886-3350</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D001672">Biocompatible Materials</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008768">Methylmethacrylates</NameOfSubstance></Chemical><Chemical><RegistryNumber>196OC77688</RegistryNumber><NameOfSubstance UI="D020366">Methylmethacrylate</NameOfSubstance></Chemical><Chemical><RegistryNumber>9005-49-6</RegistryNumber><NameOfSubstance UI="D006493">Heparin</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000369">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D001672">Biocompatible Materials</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D002387">Cataract Extraction</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005347">Fibroblasts</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005549">Foreign-Body Reaction</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D015726">Giant Cells</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D006493">Heparin</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D007910">Lenses, Intraocular</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008137">Longitudinal Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D020366">Methylmethacrylate</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008768">Methylmethacrylates</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011446">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011474">Prosthesis Design</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016896">Treatment Outcome</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D014792">Visual Acuity</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1993</Year><Month>3</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1993</Year><Month>3</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1993</Year><Month>3</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">8487171</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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