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Effect of anterior capsule polishing on fibrotic capsule opacification: Three-year results

Identifieur interne : 006C36 ( Main/Exploration ); précédent : 006C35; suivant : 006C37

Effect of anterior capsule polishing on fibrotic capsule opacification: Three-year results

Auteurs : Stefan Sacu [Autriche] ; Rupert Menapace [Autriche] ; Matthias Wirtitsch [Autriche] ; Wolf Buehl [Autriche] ; Georg Rainer [Autriche] ; Oliver Findl [Autriche]

Source :

RBID : Pascal:05-0001208

Descripteurs français

English descriptors

Abstract

Purpose: To evaluate the long-term effect of anterior capsule polishing on anterior capsule opacification (ACO) and peripheral fibrotic posterior capsule opacification (PCO). Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods: This randomized double-blind study comprised 104 eyes of 52 patients with bilateral age-related cataract. All patients received round-edged intraocular lenses (lOLs); 26 received an SI-40 IOL (Advanced Medical Optics Inc.) in both eyes, and 26 received a Silens6 IOL (Domilens) in both eyes. Both lOLs consist of different silicone material and have different haptic angulation. The SI-40 IOL has 13.0 mm open-loop poly(methyl methacrylate) (PMMA) haptics angulated by 10 degrees. The Silens6 IOL has 12.5 mm open-loop PMMA haptics with no angulation. In 1 eye, the anterior capsule was extensively polished. The anterior capsule was left unpolished in the contralateral eye, which acted as a control. Digital slitlamp photographs of the ACO and fibrotic PCO were taken with a standardized technique for 3 years postoperatively. The intensity of ACO was measured objectively (score 0% to 100%) using Adobe Photoshop software. Fibrotic PCO was graded subjectively (score 0 to 4). Results: The mean ACO was 17% in the polished eyes and 26% in the control eyes (P = .0001). The mean fibrotic PCO score was 0.5 and 1.0, respectively (P = .0007). The mean ACO was 15% in the polished SI-40 eyes and 26% in the control SI-40 eyes (P = .01). It was 19% in the polished Silens6 eyes and 26% in the control Silens6 eyes (P = .003). The mean fibrotic PCO score was 0.4 in the polished SI-40 eyes and 1.1 in the control SI-40 eyes (P = .0006). It was 0.6 in the polished Silens6 eyes and 0.9 in the control Silens6 eyes (P = .08). Conclusions: Three years after surgery, eyes in which the anterior capsule was extensively polished had less ACO and fibrotic PCO with both round-edged silicone lOLs. In eyes with Silens6 lOLs, however, the reduction in fibrotic PCO was not significant.


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Le document en format XML

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<term>Aged</term>
<term>Anterior</term>
<term>Capsule</term>
<term>Capsulorhexis</term>
<term>Cataract (etiology)</term>
<term>Double-Blind Method</term>
<term>Epithelial Cells (pathology)</term>
<term>Fibrosis</term>
<term>Follow-Up Studies</term>
<term>Hard capsule</term>
<term>Humans</term>
<term>Incidence</term>
<term>Lens Capsule, Crystalline (pathology)</term>
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<term>Lens Implantation, Intraocular</term>
<term>Lenses, Intraocular</term>
<term>Opacification</term>
<term>Ophthalmology</term>
<term>Phacoemulsification</term>
<term>Prospective Studies</term>
<term>Prosthesis Design</term>
<term>Silicone Elastomers</term>
<term>Suction (methods)</term>
<term>Surgery</term>
<term>Treatment</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en">
<term>Silicone Elastomers</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Cataract</term>
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<term>Suction</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Epithelial Cells</term>
<term>Lens Capsule, Crystalline</term>
</keywords>
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<term>Lens Capsule, Crystalline</term>
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<term>Aged</term>
<term>Capsulorhexis</term>
<term>Double-Blind Method</term>
<term>Fibrosis</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Incidence</term>
<term>Lens Implantation, Intraocular</term>
<term>Lenses, Intraocular</term>
<term>Phacoemulsification</term>
<term>Prospective Studies</term>
<term>Prosthesis Design</term>
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<term>Antérieur</term>
<term>Capsule</term>
<term>Gélule</term>
<term>Opacification</term>
<term>Chirurgie</term>
<term>Ophtalmologie</term>
<term>Traitement</term>
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<front>
<div type="abstract" xml:lang="en">Purpose: To evaluate the long-term effect of anterior capsule polishing on anterior capsule opacification (ACO) and peripheral fibrotic posterior capsule opacification (PCO). Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. Methods: This randomized double-blind study comprised 104 eyes of 52 patients with bilateral age-related cataract. All patients received round-edged intraocular lenses (lOLs); 26 received an SI-40 IOL (Advanced Medical Optics Inc.) in both eyes, and 26 received a Silens6 IOL (Domilens) in both eyes. Both lOLs consist of different silicone material and have different haptic angulation. The SI-40 IOL has 13.0 mm open-loop poly(methyl methacrylate) (PMMA) haptics angulated by 10 degrees. The Silens6 IOL has 12.5 mm open-loop PMMA haptics with no angulation. In 1 eye, the anterior capsule was extensively polished. The anterior capsule was left unpolished in the contralateral eye, which acted as a control. Digital slitlamp photographs of the ACO and fibrotic PCO were taken with a standardized technique for 3 years postoperatively. The intensity of ACO was measured objectively (score 0% to 100%) using Adobe Photoshop software. Fibrotic PCO was graded subjectively (score 0 to 4). Results: The mean ACO was 17% in the polished eyes and 26% in the control eyes (P = .0001). The mean fibrotic PCO score was 0.5 and 1.0, respectively (P = .0007). The mean ACO was 15% in the polished SI-40 eyes and 26% in the control SI-40 eyes (P = .01). It was 19% in the polished Silens6 eyes and 26% in the control Silens6 eyes (P = .003). The mean fibrotic PCO score was 0.4 in the polished SI-40 eyes and 1.1 in the control SI-40 eyes (P = .0006). It was 0.6 in the polished Silens6 eyes and 0.9 in the control Silens6 eyes (P = .08). Conclusions: Three years after surgery, eyes in which the anterior capsule was extensively polished had less ACO and fibrotic PCO with both round-edged silicone lOLs. In eyes with Silens6 lOLs, however, the reduction in fibrotic PCO was not significant.</div>
</front>
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<li>Autriche</li>
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<region name="Vienne (Autriche)">
<name sortKey="Sacu, Stefan" sort="Sacu, Stefan" uniqKey="Sacu S" first="Stefan" last="Sacu">Stefan Sacu</name>
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<name sortKey="Buehl, Wolf" sort="Buehl, Wolf" uniqKey="Buehl W" first="Wolf" last="Buehl">Wolf Buehl</name>
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<name sortKey="Wirtitsch, Matthias" sort="Wirtitsch, Matthias" uniqKey="Wirtitsch M" first="Matthias" last="Wirtitsch">Matthias Wirtitsch</name>
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