The Science of Neural Interface Systems
Identifieur interne : 004041 ( Main/Exploration ); précédent : 004040; suivant : 004042The Science of Neural Interface Systems
Auteurs : Nicholas G. Hatsopoulos ; John P. DonoghueSource :
- Annual review of neuroscience [ 0147-006X ] ; 2009.
Abstract
The ultimate goal of neural interface research is to create links between the nervous system and the outside world either by stimulating or by recording from neural tissue to treat or assist people with sensory, motor, or other disabilities of neural function. Although electrical stimulation systems have already reached widespread clinical application, neural interfaces that record neural signals to decipher movement intentions are only now beginning to develop into clinically viable systems to help paralyzed people. We begin by reviewing state-of-the-art research and early-stage clinical recording systems and focus on systems that record single-unit action potentials. We then address the potential for neural interface research to enhance basic scientific understanding of brain function by offering unique insights in neural coding and representation, plasticity, brain-behavior relations, and the neurobiology of disease. Finally, we discuss technical and scientific challenges faced by these systems before they are widely adopted by severely motor-disabled patients.
Url:
DOI: 10.1146/annurev.neuro.051508.135241
PubMed: 19400719
PubMed Central: 2921719
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000F79
- to stream Pmc, to step Curation: 000F79
- to stream Pmc, to step Checkpoint: 002022
- to stream Ncbi, to step Merge: 001128
- to stream Ncbi, to step Curation: 001128
- to stream Ncbi, to step Checkpoint: 001128
- to stream Main, to step Merge: 004109
- to stream Main, to step Curation: 004041
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Science of Neural Interface Systems</title>
<author><name sortKey="Hatsopoulos, Nicholas G" sort="Hatsopoulos, Nicholas G" uniqKey="Hatsopoulos N" first="Nicholas G." last="Hatsopoulos">Nicholas G. Hatsopoulos</name>
<affiliation><nlm:aff id="A1">Department of Organismal Biology and Anatomy, and Committees on Computational Neuroscience and Neurobiology, University of Chicago, Chicago, Illinois 60637;<email>nicho@uchicago.edu</email>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Donoghue, John P" sort="Donoghue, John P" uniqKey="Donoghue J" first="John P." last="Donoghue">John P. Donoghue</name>
<affiliation><nlm:aff id="A2">Department of Neuroscience, Brown University, Providence, Rhode Island 02912;<email>john_donoghue@brown.edu</email>
</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">19400719</idno>
<idno type="pmc">2921719</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921719</idno>
<idno type="RBID">PMC:2921719</idno>
<idno type="doi">10.1146/annurev.neuro.051508.135241</idno>
<date when="2009">2009</date>
<idno type="wicri:Area/Pmc/Corpus">000F79</idno>
<idno type="wicri:Area/Pmc/Curation">000F79</idno>
<idno type="wicri:Area/Pmc/Checkpoint">002022</idno>
<idno type="wicri:Area/Ncbi/Merge">001128</idno>
<idno type="wicri:Area/Ncbi/Curation">001128</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001128</idno>
<idno type="wicri:doubleKey">0147-006X:2009:Hatsopoulos N:the:science:of</idno>
<idno type="wicri:Area/Main/Merge">004109</idno>
<idno type="wicri:Area/Main/Curation">004041</idno>
<idno type="wicri:Area/Main/Exploration">004041</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Science of Neural Interface Systems</title>
<author><name sortKey="Hatsopoulos, Nicholas G" sort="Hatsopoulos, Nicholas G" uniqKey="Hatsopoulos N" first="Nicholas G." last="Hatsopoulos">Nicholas G. Hatsopoulos</name>
<affiliation><nlm:aff id="A1">Department of Organismal Biology and Anatomy, and Committees on Computational Neuroscience and Neurobiology, University of Chicago, Chicago, Illinois 60637;<email>nicho@uchicago.edu</email>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Donoghue, John P" sort="Donoghue, John P" uniqKey="Donoghue J" first="John P." last="Donoghue">John P. Donoghue</name>
<affiliation><nlm:aff id="A2">Department of Neuroscience, Brown University, Providence, Rhode Island 02912;<email>john_donoghue@brown.edu</email>
</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Annual review of neuroscience</title>
<idno type="ISSN">0147-006X</idno>
<idno type="eISSN">1545-4126</idno>
<imprint><date when="2009">2009</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">The ultimate goal of neural interface research is to create links between the nervous system and the outside world either by stimulating or by recording from neural tissue to treat or assist people with sensory, motor, or other disabilities of neural function. Although electrical stimulation systems have already reached widespread clinical application, neural interfaces that record neural signals to decipher movement intentions are only now beginning to develop into clinically viable systems to help paralyzed people. We begin by reviewing state-of-the-art research and early-stage clinical recording systems and focus on systems that record single-unit action potentials. We then address the potential for neural interface research to enhance basic scientific understanding of brain function by offering unique insights in neural coding and representation, plasticity, brain-behavior relations, and the neurobiology of disease. Finally, we discuss technical and scientific challenges faced by these systems before they are widely adopted by severely motor-disabled patients.</p>
</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Donoghue, John P" sort="Donoghue, John P" uniqKey="Donoghue J" first="John P." last="Donoghue">John P. Donoghue</name>
<name sortKey="Hatsopoulos, Nicholas G" sort="Hatsopoulos, Nicholas G" uniqKey="Hatsopoulos N" first="Nicholas G." last="Hatsopoulos">Nicholas G. Hatsopoulos</name>
</noCountry>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004041 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004041 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Ticri/CIDE |area= HapticV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:2921719 |texte= The Science of Neural Interface Systems }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:19400719" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a HapticV1
This area was generated with Dilib version V0.6.23. |