Effect of the optic size of a single-piece acrylic intraocular lens on posterior capsule opacification
Identifieur interne : 007021 ( Main/Exploration ); précédent : 007020; suivant : 007022Effect of the optic size of a single-piece acrylic intraocular lens on posterior capsule opacification
Auteurs : Okihiro Nishi [Japon] ; Kayo Nishi [Japon]Source :
- Journal of cataract and refractive surgery [ 0886-3350 ] ; 2003.
Descripteurs français
- Pascal (Inist)
- Wicri :
English descriptors
- KwdEn :
- Acrylic Resins, Acrylic elastomer, Animal, Animals, Biocompatible Materials, Capsule, Cataract (pathology), Cataract (prevention & control), Complication, Experimental study, Iatrogenic, Intraocular lens, Lens, Lens Capsule, Crystalline (pathology), Lens Implantation, Intraocular, Lenses, Intraocular, Opacification, Optics, Posterior, Posterior chamber, Postoperative, Prosthesis Design, Rabbit, Rabbits, Size, Tissue Adhesions.
- MESH :
- chemical : Acrylic Resins, Biocompatible Materials.
- pathology : Cataract, Lens Capsule, Crystalline.
- prevention & control : Cataract.
- Animals, Lens Implantation, Intraocular, Lenses, Intraocular, Prosthesis Design, Rabbits, Tissue Adhesions.
Abstract
Purpose: To investigate the effect of the optic size of an intraocular lens (IOL) with sharp optic edges on posterior capsule opacification (PCO). Setting: Nishi Eye Hospital, Osaka, Japan. Methods: In 5 rabbits, a single-piece 5.5 mm optic AcrySof® IOL (Alcon Laboratories) was implanted in 1 eye and a specially fabricated single-piece 7.0 mm optic AcrySof IOL was implanted in the contralateral eye. Histopathological examinations were performed 3 weeks after surgery. Results: On posterior views, less PCO was noted with the 5.5 mm optic in all rabbits except 1. Histopathological sections demonstrated adhesion of the anterior and posterior capsules between the haptic and optic and the formation of a sharp capsular bend at the posterior optic edge in 3 eyes with the 5.5 mm optic but in no eye with the 7.0 mm optic. Abundant PCO was noted when a sharp capsular bend had not formed. Conclusions: Capsular adhesion is a prerequisite of capsular-bend formation. The sharp optic edge alone does not provide a substantial barrier when a capsular bend is not formed. Bulky haptics such as those of the single-piece AcrySof and large optics may hamper capsular adhesion and bend formation.
Affiliations:
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Le document en format XML
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<author><name sortKey="Nishi, Kayo" sort="Nishi, Kayo" uniqKey="Nishi K" first="Kayo" last="Nishi">Kayo Nishi</name>
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<series><title level="j" type="main">Journal of cataract and refractive surgery</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acrylic Resins</term>
<term>Acrylic elastomer</term>
<term>Animal</term>
<term>Animals</term>
<term>Biocompatible Materials</term>
<term>Capsule</term>
<term>Cataract (pathology)</term>
<term>Cataract (prevention & control)</term>
<term>Complication</term>
<term>Experimental study</term>
<term>Iatrogenic</term>
<term>Intraocular lens</term>
<term>Lens</term>
<term>Lens Capsule, Crystalline (pathology)</term>
<term>Lens Implantation, Intraocular</term>
<term>Lenses, Intraocular</term>
<term>Opacification</term>
<term>Optics</term>
<term>Posterior</term>
<term>Posterior chamber</term>
<term>Postoperative</term>
<term>Prosthesis Design</term>
<term>Rabbit</term>
<term>Rabbits</term>
<term>Size</term>
<term>Tissue Adhesions</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Acrylic Resins</term>
<term>Biocompatible Materials</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Cataract</term>
<term>Lens Capsule, Crystalline</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Cataract</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Lens Implantation, Intraocular</term>
<term>Lenses, Intraocular</term>
<term>Prosthesis Design</term>
<term>Rabbits</term>
<term>Tissue Adhesions</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Lentille intraoculaire</term>
<term>Chambre postérieure</term>
<term>Opacification</term>
<term>Capsule</term>
<term>Postérieur</term>
<term>Cristallin</term>
<term>Acrylate élastomère</term>
<term>Lapin</term>
<term>Animal</term>
<term>Etude expérimentale</term>
<term>Optique</term>
<term>Taille</term>
<term>Complication</term>
<term>Postopératoire</term>
<term>Iatrogène</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Lapin</term>
<term>Optique</term>
</keywords>
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<front><div type="abstract" xml:lang="en">Purpose: To investigate the effect of the optic size of an intraocular lens (IOL) with sharp optic edges on posterior capsule opacification (PCO). Setting: Nishi Eye Hospital, Osaka, Japan. Methods: In 5 rabbits, a single-piece 5.5 mm optic AcrySof® IOL (Alcon Laboratories) was implanted in 1 eye and a specially fabricated single-piece 7.0 mm optic AcrySof IOL was implanted in the contralateral eye. Histopathological examinations were performed 3 weeks after surgery. Results: On posterior views, less PCO was noted with the 5.5 mm optic in all rabbits except 1. Histopathological sections demonstrated adhesion of the anterior and posterior capsules between the haptic and optic and the formation of a sharp capsular bend at the posterior optic edge in 3 eyes with the 5.5 mm optic but in no eye with the 7.0 mm optic. Abundant PCO was noted when a sharp capsular bend had not formed. Conclusions: Capsular adhesion is a prerequisite of capsular-bend formation. The sharp optic edge alone does not provide a substantial barrier when a capsular bend is not formed. Bulky haptics such as those of the single-piece AcrySof and large optics may hamper capsular adhesion and bend formation.</div>
</front>
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<affiliations><list><country><li>Japon</li>
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<name sortKey="Nishi, Kayo" sort="Nishi, Kayo" uniqKey="Nishi K" first="Kayo" last="Nishi">Kayo Nishi</name>
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