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Fellow-eye comparison of posterior capsule opacification rates after implantation of 1CU accommodating and AcrySof MA30 monofocal intraocular lenses

Identifieur interne : 005A19 ( Main/Exploration ); précédent : 005A18; suivant : 005A20

Fellow-eye comparison of posterior capsule opacification rates after implantation of 1CU accommodating and AcrySof MA30 monofocal intraocular lenses

Auteurs : Joanne Hancox [Royaume-Uni] ; David Spalton [Royaume-Uni] ; Catherine Heatley [Royaume-Uni] ; Hari Jayaram [Royaume-Uni] ; Jennifer Yip [Royaume-Uni] ; James Boyce [Royaume-Uni] ; John Marshall [Royaume-Uni]

Source :

RBID : Pascal:07-0165996

Descripteurs français

English descriptors

Abstract

PURPOSE: To measure posterior capsule opacification (PCO) and neodymium:YAG (Nd:YAG) capsulotomy rates between the AcrySof MA30 intraocular lens (10L) (Alcon) and the 1CU 10L (Human-Optics) in a fellow-eye comparison. SETTING: Ophthalmology Department, St. Thomas' Hospital, London, United Kingdom. METHODS: Thirty patients who had bilateral cataract surgery with a 1CU IOL prospectively randomly allocated to 1 eye and an AcrySof MA30 monofocal 10L to the other eye were examined. Best corrected distance visual acuity was recorded using the Early Treatment Diabetic Retinopathy Study logMAR chart. Digital retroillumination images of the posterior capsule were taken with the pupil dilated and analyzed with POCO software. RESULTS: Eyes with the 1 CU 10L had significantly higher PCO rates than eyes with the MA30 10L at all time points. By 2 years after surgery, 50% of eyes with a 1CU 10L had required Nd:YAG capsulotomy compared with no eyes with an MA30 10L. There was no significant difference in visual acuity at any time point when post Nd:YAG capsulotomy was taken in to account. CONCLUSIONS: The 1 CU 10L has 4 broad optic-haptic junctions where the square-edged barrier is breached; this appeared to allow passage of lens epithelial cells, leading to an increase in PCO. However, the increased PCO cannot be attributed to this alone as the 1 CU is hydrophilic, a factor known to be associated with higher PCO rates.


Affiliations:


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Le document en format XML

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<term>Comparative study</term>
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<term>Prospective Studies</term>
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<term>Accommodation, Ocular</term>
<term>Aged</term>
<term>Female</term>
<term>Humans</term>
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<term>Postoperative Complications</term>
<term>Prospective Studies</term>
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<term>Taux</term>
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<front>
<div type="abstract" xml:lang="en">PURPOSE: To measure posterior capsule opacification (PCO) and neodymium:YAG (Nd:YAG) capsulotomy rates between the AcrySof MA30 intraocular lens (10L) (Alcon) and the 1CU 10L (Human-Optics) in a fellow-eye comparison. SETTING: Ophthalmology Department, St. Thomas' Hospital, London, United Kingdom. METHODS: Thirty patients who had bilateral cataract surgery with a 1CU IOL prospectively randomly allocated to 1 eye and an AcrySof MA30 monofocal 10L to the other eye were examined. Best corrected distance visual acuity was recorded using the Early Treatment Diabetic Retinopathy Study logMAR chart. Digital retroillumination images of the posterior capsule were taken with the pupil dilated and analyzed with POCO software. RESULTS: Eyes with the 1 CU 10L had significantly higher PCO rates than eyes with the MA30 10L at all time points. By 2 years after surgery, 50% of eyes with a 1CU 10L had required Nd:YAG capsulotomy compared with no eyes with an MA30 10L. There was no significant difference in visual acuity at any time point when post Nd:YAG capsulotomy was taken in to account. CONCLUSIONS: The 1 CU 10L has 4 broad optic-haptic junctions where the square-edged barrier is breached; this appeared to allow passage of lens epithelial cells, leading to an increase in PCO. However, the increased PCO cannot be attributed to this alone as the 1 CU is hydrophilic, a factor known to be associated with higher PCO rates.</div>
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<name sortKey="Boyce, James" sort="Boyce, James" uniqKey="Boyce J" first="James" last="Boyce">James Boyce</name>
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