Quantitative upper airway endoscopy with swept-source anatomical optical coherence tomography
Identifieur interne : 000F25 ( Main/Exploration ); précédent : 000F24; suivant : 000F26Quantitative upper airway endoscopy with swept-source anatomical optical coherence tomography
Auteurs : Kushal Wijesundara [États-Unis] ; Carlton Zdanski [États-Unis] ; Julia Kimbell [États-Unis] ; Hillel Price [États-Unis] ; Nicusor Iftimia [États-Unis] ; Amy L. Oldenburg [États-Unis]Source :
- Biomedical Optics Express [ 2156-7085 ] ; 2014.
Abstract
Minimally invasive imaging of upper airway obstructions in children and adults is needed to improve clinical decision-making. Toward this goal, we demonstrate an anatomical optical coherence tomography (aOCT) system delivered via a small-bore, flexible endoscope to quantify the upper airway lumen geometry. Helical scans were obtained from a proximally-scanned fiber-optic catheter of 820 μm outer diameter and >2 mm focal length. Coupled with a long coherence length wavelength-swept light source, the system exhibited an SNR roll-off of < 10 dB over a 10 mm range. Operating at 10 rotations/s, the average accuracy of segmented cross-sectional areas was found to be −1.4 ± 1.0%. To demonstrate the capability of this system, aOCT was performed on a pediatric airway phantom and on
Url:
DOI: 10.1364/BOE.5.000788
PubMed: 24688814
PubMed Central: 3959831
Affiliations:
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Oldenburg</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3255,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4">Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7513,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff5">Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7575,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Biomedical Optics Express</title><idno type="eISSN">2156-7085</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Minimally invasive imaging of upper airway obstructions in children and adults is needed to improve clinical decision-making. Toward this goal, we demonstrate an anatomical optical coherence tomography (aOCT) system delivered via a small-bore, flexible endoscope to quantify the upper airway lumen geometry. Helical scans were obtained from a proximally-scanned fiber-optic catheter of 820 μm outer diameter and >2 mm focal length. Coupled with a long coherence length wavelength-swept light source, the system exhibited an SNR roll-off of < 10 dB over a 10 mm range. Operating at 10 rotations/s, the average accuracy of segmented cross-sectional areas was found to be −1.4 ± 1.0%. To demonstrate the capability of this system, aOCT was performed on a pediatric airway phantom and on <italic>ex vivo</italic> swine trachea. The ability for quantitative endoscopy afforded by this system can aid in diagnosis, medical and surgical decision making, and predictive modeling of upper airway obstructive disorders.</p></div></front></TEI><affiliations><list><country><li>États-Unis</li></country></list><tree><country name="États-Unis"><noRegion><name sortKey="Wijesundara, Kushal" sort="Wijesundara, Kushal" uniqKey="Wijesundara K" first="Kushal" last="Wijesundara">Kushal Wijesundara</name></noRegion><name sortKey="Iftimia, Nicusor" sort="Iftimia, Nicusor" uniqKey="Iftimia N" first="Nicusor" last="Iftimia">Nicusor Iftimia</name><name sortKey="Kimbell, Julia" sort="Kimbell, Julia" uniqKey="Kimbell J" first="Julia" last="Kimbell">Julia Kimbell</name><name sortKey="Oldenburg, Amy L" sort="Oldenburg, Amy L" uniqKey="Oldenburg A" first="Amy L." last="Oldenburg">Amy L. Oldenburg</name><name sortKey="Oldenburg, Amy L" sort="Oldenburg, Amy L" uniqKey="Oldenburg A" first="Amy L." last="Oldenburg">Amy L. Oldenburg</name><name sortKey="Oldenburg, Amy L" sort="Oldenburg, Amy L" uniqKey="Oldenburg A" first="Amy L." last="Oldenburg">Amy L. Oldenburg</name><name sortKey="Price, Hillel" sort="Price, Hillel" uniqKey="Price H" first="Hillel" last="Price">Hillel Price</name><name sortKey="Zdanski, Carlton" sort="Zdanski, Carlton" uniqKey="Zdanski C" first="Carlton" last="Zdanski">Carlton Zdanski</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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