Quantitative upper airway endoscopy with swept-source anatomical optical coherence tomography
Identifieur interne : 000F25 ( Main/Merge ); précédent : 000F24; suivant : 000F26Quantitative upper airway endoscopy with swept-source anatomical optical coherence tomography
Auteurs : Kushal Wijesundara [États-Unis] ; Carlton Zdanski [États-Unis] ; Julia Kimbell [États-Unis] ; Hillel Price [États-Unis] ; Nicusor Iftimia [États-Unis] ; Amy L. Oldenburg [États-Unis]Source :
- Biomedical Optics Express [ 2156-7085 ] ; 2014.
Abstract
Minimally invasive imaging of upper airway obstructions in children and adults is needed to improve clinical decision-making. Toward this goal, we demonstrate an anatomical optical coherence tomography (aOCT) system delivered via a small-bore, flexible endoscope to quantify the upper airway lumen geometry. Helical scans were obtained from a proximally-scanned fiber-optic catheter of 820 μm outer diameter and >2 mm focal length. Coupled with a long coherence length wavelength-swept light source, the system exhibited an SNR roll-off of < 10 dB over a 10 mm range. Operating at 10 rotations/s, the average accuracy of segmented cross-sectional areas was found to be −1.4 ± 1.0%. To demonstrate the capability of this system, aOCT was performed on a pediatric airway phantom and on
Url:
DOI: 10.1364/BOE.5.000788
PubMed: 24688814
PubMed Central: 3959831
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PMC:3959831Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Minimally invasive imaging of upper airway obstructions in children and adults is needed to improve clinical decision-making. Toward this goal, we demonstrate an anatomical optical coherence tomography (aOCT) system delivered via a small-bore, flexible endoscope to quantify the upper airway lumen geometry. Helical scans were obtained from a proximally-scanned fiber-optic catheter of 820 μm outer diameter and >2 mm focal length. Coupled with a long coherence length wavelength-swept light source, the system exhibited an SNR roll-off of < 10 dB over a 10 mm range. Operating at 10 rotations/s, the average accuracy of segmented cross-sectional areas was found to be −1.4 ± 1.0%. To demonstrate the capability of this system, aOCT was performed on a pediatric airway phantom and on <italic>ex vivo</italic>
swine trachea. The ability for quantitative endoscopy afforded by this system can aid in diagnosis, medical and surgical decision making, and predictive modeling of upper airway obstructive disorders.</p>
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