Hydrophilic acrylic intraocular lens optic and haptics Opacification in a diabetic patient bilateral case report and clinicopathologic correlation
Identifieur interne : 007363 ( Main/Curation ); précédent : 007362; suivant : 007364Hydrophilic acrylic intraocular lens optic and haptics Opacification in a diabetic patient bilateral case report and clinicopathologic correlation
Auteurs : Suresh K. Pandey [États-Unis] ; Liliana Werner [États-Unis] ; David J. Apple [États-Unis] ; Mahmut Kaskaloglu [Turquie]Source :
- Ophthalmology : (Rochester, MN) [ 0161-6420 ] ; 2002.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Diabète, Biomatériau, Personne âgée.
English descriptors
- KwdEn :
- Acrylic Resins, Acrylic polymer, Biomaterial, Calcinosis (diagnosis), Calcinosis (etiology), Case study, Cataract, Complication, Device Removal, Diabetes Mellitus, Type 2 (complications), Diabetes mellitus, Diabetic Retinopathy (complications), Elderly, Electron Probe Microanalysis, Female, Humans, Hydrophilic compound, Implantation, Intraocular, Intraocular lens, Lens Implantation, Intraocular, Lenses, Intraocular, Microscopy, Electron, Scanning, Middle Aged, Opacification, Phacoemulsification, Prosthesis Failure, Reoperation, Treatment, Visual Acuity.
- MESH :
- chemical : Acrylic Resins.
- complications : Diabetes Mellitus, Type 2, Diabetic Retinopathy.
- diagnosis : Calcinosis.
- etiology : Calcinosis.
- Device Removal, Electron Probe Microanalysis, Female, Humans, Lens Implantation, Intraocular, Lenses, Intraocular, Microscopy, Electron, Scanning, Middle Aged, Phacoemulsification, Prosthesis Failure, Reoperation, Visual Acuity.
Abstract
Objective: To report clinicopathologic and ultrastructural features of two opacified single-piece hydrophilic acrylic intraocular lenses (lOLs) explanted from a diabetic patient. Design: Interventional case report with clinicopathologic correlation. Setting: A 64-year-old white female underwent phacoemulsification and implantation of a single-piece hydrophilic acrylic lens (SC60B-OUV; Medical Developmental Research, Inc., Clear Water, FL) in October 1998 in the left eye and in July 1999 in the right eye. The best-corrected visual acuity after surgery was 20/60 in the left eye and 20/50 in the right eye. The patient had a marked decrease in visual acuity in June 2000 as a result of a milky, white opalescence of both lenses. Intraocular lens explantation and exchange was performed in both eyes and the explanted lOLs were submitted to our center for detailed pathologic, histochemical, and ultrastructural evaluation. They were stained with alizarin red and the von Kossa method for calcium, and also underwent scanning electron microscopy and energy dispersive radiograph spectroscopy to ascertain the nature of the deposits leading to opacification. Main Outcome Measures: Documentation of calcium deposits confirmed by histochemical stains and surface analyses. Results: Opacification of the IOL was found to be the cause of decreased visual acuity. The opacification involved both the IOL optic and the haptics in the left eye and was confined to the IOL optic in the right eye. Histochemical and ultrastructural analyses revealed that the opacity was caused by deposition of calcium and phosphate within the lens optic and haptics. Conclusions: There are two features that distinguish this case from those reported earlier. This is the first clinicopathologic report of lens opacification that has involved completely the lens optic and the haptics. Second, these two explanted lOLs document the first bilateral case. This process of intraoptic and haptic opacification represents dystrophic calcification of unknown cause. Diabetic patients appear to be more severely and more often affected by lens opacification. Long-term follow-up of diabetic patients implanted with this IOL design should be maintained by surgeons and manufacturers.
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Pandey</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J." last="Apple">David J. Apple</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Kaskaloglu, Mahmut" sort="Kaskaloglu, Mahmut" uniqKey="Kaskaloglu M" first="Mahmut" last="Kaskaloglu">Mahmut Kaskaloglu</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Ege University</s1><s2>Alsancak Izmir</s2><s3>TUR</s3><sZ>4 aut.</sZ></inist:fA14><country>Turquie</country><wicri:noRegion>Ege University</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Ophthalmology : (Rochester, MN)</title><title level="j" type="abbreviated">Ophthalmology : (Rochester MN)</title><idno type="ISSN">0161-6420</idno><imprint><date when="2002">2002</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Ophthalmology : (Rochester, MN)</title><title level="j" type="abbreviated">Ophthalmology : (Rochester MN)</title><idno type="ISSN">0161-6420</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acrylic Resins</term><term>Acrylic polymer</term><term>Biomaterial</term><term>Calcinosis (diagnosis)</term><term>Calcinosis (etiology)</term><term>Case study</term><term>Cataract</term><term>Complication</term><term>Device Removal</term><term>Diabetes Mellitus, Type 2 (complications)</term><term>Diabetes mellitus</term><term>Diabetic Retinopathy (complications)</term><term>Elderly</term><term>Electron Probe Microanalysis</term><term>Female</term><term>Humans</term><term>Hydrophilic compound</term><term>Implantation</term><term>Intraocular</term><term>Intraocular lens</term><term>Lens Implantation, Intraocular</term><term>Lenses, Intraocular</term><term>Microscopy, Electron, Scanning</term><term>Middle Aged</term><term>Opacification</term><term>Phacoemulsification</term><term>Prosthesis Failure</term><term>Reoperation</term><term>Treatment</term><term>Visual Acuity</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Acrylic Resins</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Diabetes Mellitus, Type 2</term><term>Diabetic Retinopathy</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Calcinosis</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Calcinosis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Device Removal</term><term>Electron Probe Microanalysis</term><term>Female</term><term>Humans</term><term>Lens Implantation, Intraocular</term><term>Lenses, Intraocular</term><term>Microscopy, Electron, Scanning</term><term>Middle Aged</term><term>Phacoemulsification</term><term>Prosthesis Failure</term><term>Reoperation</term><term>Visual Acuity</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Diabète</term><term>Traitement</term><term>Cataracte</term><term>Implantation</term><term>Intraoculaire</term><term>Lentille intraoculaire</term><term>Complication</term><term>Opacification</term><term>Composé hydrophile</term><term>Acrylique dérivé polymère</term><term>Biomatériau</term><term>Etude cas</term><term>Personne âgée</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Diabète</term><term>Biomatériau</term><term>Personne âgée</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objective: To report clinicopathologic and ultrastructural features of two opacified single-piece hydrophilic acrylic intraocular lenses (lOLs) explanted from a diabetic patient. Design: Interventional case report with clinicopathologic correlation. Setting: A 64-year-old white female underwent phacoemulsification and implantation of a single-piece hydrophilic acrylic lens (SC60B-OUV; Medical Developmental Research, Inc., Clear Water, FL) in October 1998 in the left eye and in July 1999 in the right eye. The best-corrected visual acuity after surgery was 20/60 in the left eye and 20/50 in the right eye. The patient had a marked decrease in visual acuity in June 2000 as a result of a milky, white opalescence of both lenses. Intraocular lens explantation and exchange was performed in both eyes and the explanted lOLs were submitted to our center for detailed pathologic, histochemical, and ultrastructural evaluation. They were stained with alizarin red and the von Kossa method for calcium, and also underwent scanning electron microscopy and energy dispersive radiograph spectroscopy to ascertain the nature of the deposits leading to opacification. Main Outcome Measures: Documentation of calcium deposits confirmed by histochemical stains and surface analyses. Results: Opacification of the IOL was found to be the cause of decreased visual acuity. The opacification involved both the IOL optic and the haptics in the left eye and was confined to the IOL optic in the right eye. Histochemical and ultrastructural analyses revealed that the opacity was caused by deposition of calcium and phosphate within the lens optic and haptics. Conclusions: There are two features that distinguish this case from those reported earlier. This is the first clinicopathologic report of lens opacification that has involved completely the lens optic and the haptics. Second, these two explanted lOLs document the first bilateral case. This process of intraoptic and haptic opacification represents dystrophic calcification of unknown cause. Diabetic patients appear to be more severely and more often affected by lens opacification. Long-term follow-up of diabetic patients implanted with this IOL design should be maintained by surgeons and manufacturers.</div></front></TEI><double idat="0161-6420:2002:Pandey S:hydrophilic:acrylic:intraocular"><INIST><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Hydrophilic acrylic intraocular lens optic and haptics Opacification in a diabetic patient bilateral case report and clinicopathologic correlation</title><author><name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K." last="Pandey">Suresh K. Pandey</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J." last="Apple">David J. Apple</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Kaskaloglu, Mahmut" sort="Kaskaloglu, Mahmut" uniqKey="Kaskaloglu M" first="Mahmut" last="Kaskaloglu">Mahmut Kaskaloglu</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Ege University</s1><s2>Alsancak Izmir</s2><s3>TUR</s3><sZ>4 aut.</sZ></inist:fA14><country>Turquie</country><wicri:noRegion>Ege University</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">03-0137391</idno><date when="2002">2002</date><idno type="stanalyst">PASCAL 03-0137391 INIST</idno><idno type="RBID">Pascal:03-0137391</idno><idno type="wicri:Area/PascalFrancis/Corpus">001198</idno><idno type="wicri:Area/PascalFrancis/Curation">000313</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000F68</idno><idno type="wicri:doubleKey">0161-6420:2002:Pandey S:hydrophilic:acrylic:intraocular</idno><idno type="wicri:Area/Main/Merge">007908</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Hydrophilic acrylic intraocular lens optic and haptics Opacification in a diabetic patient bilateral case report and clinicopathologic correlation</title><author><name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K." last="Pandey">Suresh K. Pandey</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J." last="Apple">David J. Apple</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Kaskaloglu, Mahmut" sort="Kaskaloglu, Mahmut" uniqKey="Kaskaloglu M" first="Mahmut" last="Kaskaloglu">Mahmut Kaskaloglu</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Ege University</s1><s2>Alsancak Izmir</s2><s3>TUR</s3><sZ>4 aut.</sZ></inist:fA14><country>Turquie</country><wicri:noRegion>Ege University</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Ophthalmology : (Rochester, MN)</title><title level="j" type="abbreviated">Ophthalmology : (Rochester MN)</title><idno type="ISSN">0161-6420</idno><imprint><date when="2002">2002</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Ophthalmology : (Rochester, MN)</title><title level="j" type="abbreviated">Ophthalmology : (Rochester MN)</title><idno type="ISSN">0161-6420</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acrylic polymer</term><term>Biomaterial</term><term>Case study</term><term>Cataract</term><term>Complication</term><term>Diabetes mellitus</term><term>Elderly</term><term>Hydrophilic compound</term><term>Implantation</term><term>Intraocular</term><term>Intraocular lens</term><term>Opacification</term><term>Treatment</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Diabète</term><term>Traitement</term><term>Cataracte</term><term>Implantation</term><term>Intraoculaire</term><term>Lentille intraoculaire</term><term>Complication</term><term>Opacification</term><term>Composé hydrophile</term><term>Acrylique dérivé polymère</term><term>Biomatériau</term><term>Etude cas</term><term>Personne âgée</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Diabète</term><term>Biomatériau</term><term>Personne âgée</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objective: To report clinicopathologic and ultrastructural features of two opacified single-piece hydrophilic acrylic intraocular lenses (lOLs) explanted from a diabetic patient. Design: Interventional case report with clinicopathologic correlation. Setting: A 64-year-old white female underwent phacoemulsification and implantation of a single-piece hydrophilic acrylic lens (SC60B-OUV; Medical Developmental Research, Inc., Clear Water, FL) in October 1998 in the left eye and in July 1999 in the right eye. The best-corrected visual acuity after surgery was 20/60 in the left eye and 20/50 in the right eye. The patient had a marked decrease in visual acuity in June 2000 as a result of a milky, white opalescence of both lenses. Intraocular lens explantation and exchange was performed in both eyes and the explanted lOLs were submitted to our center for detailed pathologic, histochemical, and ultrastructural evaluation. They were stained with alizarin red and the von Kossa method for calcium, and also underwent scanning electron microscopy and energy dispersive radiograph spectroscopy to ascertain the nature of the deposits leading to opacification. Main Outcome Measures: Documentation of calcium deposits confirmed by histochemical stains and surface analyses. Results: Opacification of the IOL was found to be the cause of decreased visual acuity. The opacification involved both the IOL optic and the haptics in the left eye and was confined to the IOL optic in the right eye. Histochemical and ultrastructural analyses revealed that the opacity was caused by deposition of calcium and phosphate within the lens optic and haptics. Conclusions: There are two features that distinguish this case from those reported earlier. This is the first clinicopathologic report of lens opacification that has involved completely the lens optic and the haptics. Second, these two explanted lOLs document the first bilateral case. This process of intraoptic and haptic opacification represents dystrophic calcification of unknown cause. Diabetic patients appear to be more severely and more often affected by lens opacification. Long-term follow-up of diabetic patients implanted with this IOL design should be maintained by surgeons and manufacturers.</div></front></TEI></INIST><PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Hydrophilic acrylic intraocular lens optic and haptics opacification in a diabetic patient: bilateral case report and clinicopathologic correlation.</title><author><name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K" last="Pandey">Suresh K. Pandey</name><affiliation wicri:level="2"><nlm:affiliation>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina</wicri:regionArea><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name></author><author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J" last="Apple">David J. Apple</name></author><author><name sortKey="Kaskaloglu, Mahmut" sort="Kaskaloglu, Mahmut" uniqKey="Kaskaloglu M" first="Mahmut" last="Kaskaloglu">Mahmut Kaskaloglu</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2002">2002</date><idno type="RBID">pubmed:12414413</idno><idno type="pmid">12414413</idno><idno type="wicri:Area/PubMed/Corpus">001C43</idno><idno type="wicri:Area/PubMed/Curation">001C43</idno><idno type="wicri:Area/PubMed/Checkpoint">001A10</idno><idno type="wicri:Area/Ncbi/Merge">000339</idno><idno type="wicri:Area/Ncbi/Curation">000339</idno><idno type="wicri:Area/Ncbi/Checkpoint">000339</idno><idno type="wicri:doubleKey">0161-6420:2002:Pandey S:hydrophilic:acrylic:intraocular</idno><idno type="wicri:Area/Main/Merge">007603</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Hydrophilic acrylic intraocular lens optic and haptics opacification in a diabetic patient: bilateral case report and clinicopathologic correlation.</title><author><name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K" last="Pandey">Suresh K. Pandey</name><affiliation wicri:level="2"><nlm:affiliation>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina</wicri:regionArea><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name></author><author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J" last="Apple">David J. Apple</name></author><author><name sortKey="Kaskaloglu, Mahmut" sort="Kaskaloglu, Mahmut" uniqKey="Kaskaloglu M" first="Mahmut" last="Kaskaloglu">Mahmut Kaskaloglu</name></author></analytic><series><title level="j">Ophthalmology</title><idno type="ISSN">0161-6420</idno><imprint><date when="2002" type="published">2002</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acrylic Resins</term><term>Calcinosis (diagnosis)</term><term>Calcinosis (etiology)</term><term>Device Removal</term><term>Diabetes Mellitus, Type 2 (complications)</term><term>Diabetic Retinopathy (complications)</term><term>Electron Probe Microanalysis</term><term>Female</term><term>Humans</term><term>Lens Implantation, Intraocular</term><term>Lenses, Intraocular</term><term>Microscopy, Electron, Scanning</term><term>Middle Aged</term><term>Phacoemulsification</term><term>Prosthesis Failure</term><term>Reoperation</term><term>Visual Acuity</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Acrylic Resins</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Diabetes Mellitus, Type 2</term><term>Diabetic Retinopathy</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Calcinosis</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Calcinosis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Device Removal</term><term>Electron Probe Microanalysis</term><term>Female</term><term>Humans</term><term>Lens Implantation, Intraocular</term><term>Lenses, Intraocular</term><term>Microscopy, Electron, Scanning</term><term>Middle Aged</term><term>Phacoemulsification</term><term>Prosthesis Failure</term><term>Reoperation</term><term>Visual Acuity</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To report clinicopathologic and ultrastructural features of two opacified single-piece hydrophilic acrylic intraocular lenses (IOLs) explanted from a diabetic patient.</div></front></TEI></PubMed></double></record>Pour manipuler ce document sous Unix (Dilib)
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