Half-life of intracameral gentamicin after phacoemulsification
Identifieur interne : 004472 ( Istex/Corpus ); précédent : 004471; suivant : 004473Half-life of intracameral gentamicin after phacoemulsification
Auteurs : Ordan J. Lehmann ; John P. Thompson ; Les O. White ; Martin F. Keys ; Michael J. CampbellSource :
- Journal of Cataract & Refractive Surgery [ 0886-3350 ] ; 1997.
Abstract
Purpose: To determine the half-life of intracameral gentamicin administered during phacoemulsification.Setting: Southampton Eye Unit, Southampton General Hospital, England.Methods: Thirty-one patients having scleral tunnel phacoemulsification were given intracameral gentamicin in the irrigation fluid. Samples of fluid were taken from the anterior chamber at the end of the operation and at various times postoperatively. The concentration of gentamicin in the samples was determined by fluorescence polarization immunoassay and the half-life calculated for a single compartment model using a peeling algorithm.Results: The concentration of gentamicin in the anterior chamber after phacoemulsification decreased by half every 51 minutes (95% confidence interval, 42 to 66 minutes).Conclusion: Intracameral gentamicin was cleared from the anterior chamber after phacoemulsification at a rate that prevents the maintainance of the bactericidal levels required for reliable antibiotic prophylaxis.
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DOI: 10.1016/S0886-3350(97)80248-9
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<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Half-life of intracameral gentamicin after phacoemulsification</title><author><name sortKey="Lehmann, Ordan J" sort="Lehmann, Ordan J" uniqKey="Lehmann O" first="Ordan J." last="Lehmann">Ordan J. Lehmann</name><affiliation><mods:affiliation>The Southampton Eye Unit, England</mods:affiliation></affiliation><affiliation><mods:affiliation>Reprint requests to Ordan J. Lehmann, MD, Department of Ophtbalmology, Salisbury District Hospital, Salisbury Wiltshire SP2 8BJ, England.</mods:affiliation></affiliation></author><author><name sortKey="Thompson, John P" sort="Thompson, John P" uniqKey="Thompson J" first="John P." last="Thompson">John P. Thompson</name><affiliation><mods:affiliation>Southampton General Hospital, Clinical Pharmacology Group, England</mods:affiliation></affiliation></author><author><name sortKey="White, Les O" sort="White, Les O" uniqKey="White L" first="Les O." last="White">Les O. White</name><affiliation><mods:affiliation>Southampton University, and Bristol Centre for Antimicrobial Research and Evaluation, Southmead Hospital, Bristol, England</mods:affiliation></affiliation></author><author><name sortKey="Keys, Martin F" sort="Keys, Martin F" uniqKey="Keys M" first="Martin F." last="Keys">Martin F. Keys</name><affiliation><mods:affiliation>Public Health Library, England</mods:affiliation></affiliation></author><author><name sortKey="Campbell, Michael J" sort="Campbell, Michael J" uniqKey="Campbell M" first="Michael J." last="Campbell">Michael J. Campbell</name><affiliation><mods:affiliation>Medical Statistics and Computing, England</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:D738A383190636AFF0A4A09DCD91D8AEA4432FBD</idno><date when="1997" year="1997">1997</date><idno type="doi">10.1016/S0886-3350(97)80248-9</idno><idno type="url">https://api.istex.fr/document/D738A383190636AFF0A4A09DCD91D8AEA4432FBD/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">004472</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Half-life of intracameral gentamicin after phacoemulsification</title><author><name sortKey="Lehmann, Ordan J" sort="Lehmann, Ordan J" uniqKey="Lehmann O" first="Ordan J." last="Lehmann">Ordan J. Lehmann</name><affiliation><mods:affiliation>The Southampton Eye Unit, England</mods:affiliation></affiliation><affiliation><mods:affiliation>Reprint requests to Ordan J. Lehmann, MD, Department of Ophtbalmology, Salisbury District Hospital, Salisbury Wiltshire SP2 8BJ, England.</mods:affiliation></affiliation></author><author><name sortKey="Thompson, John P" sort="Thompson, John P" uniqKey="Thompson J" first="John P." last="Thompson">John P. Thompson</name><affiliation><mods:affiliation>Southampton General Hospital, Clinical Pharmacology Group, England</mods:affiliation></affiliation></author><author><name sortKey="White, Les O" sort="White, Les O" uniqKey="White L" first="Les O." last="White">Les O. White</name><affiliation><mods:affiliation>Southampton University, and Bristol Centre for Antimicrobial Research and Evaluation, Southmead Hospital, Bristol, England</mods:affiliation></affiliation></author><author><name sortKey="Keys, Martin F" sort="Keys, Martin F" uniqKey="Keys M" first="Martin F." last="Keys">Martin F. Keys</name><affiliation><mods:affiliation>Public Health Library, England</mods:affiliation></affiliation></author><author><name sortKey="Campbell, Michael J" sort="Campbell, Michael J" uniqKey="Campbell M" first="Michael J." last="Campbell">Michael J. Campbell</name><affiliation><mods:affiliation>Medical Statistics and Computing, England</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Cataract & Refractive Surgery</title><title level="j" type="abbrev">JCRS</title><idno type="ISSN">0886-3350</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1997">1997</date><biblScope unit="volume">23</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="883">883</biblScope><biblScope unit="page" to="888">888</biblScope></imprint><idno type="ISSN">0886-3350</idno></series><idno type="istex">D738A383190636AFF0A4A09DCD91D8AEA4432FBD</idno><idno type="DOI">10.1016/S0886-3350(97)80248-9</idno><idno type="PII">S0886-3350(97)80248-9</idno><idno type="ArticleID">80248</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0886-3350</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Purpose: To determine the half-life of intracameral gentamicin administered during phacoemulsification.Setting: Southampton Eye Unit, Southampton General Hospital, England.Methods: Thirty-one patients having scleral tunnel phacoemulsification were given intracameral gentamicin in the irrigation fluid. Samples of fluid were taken from the anterior chamber at the end of the operation and at various times postoperatively. The concentration of gentamicin in the samples was determined by fluorescence polarization immunoassay and the half-life calculated for a single compartment model using a peeling algorithm.Results: The concentration of gentamicin in the anterior chamber after phacoemulsification decreased by half every 51 minutes (95% confidence interval, 42 to 66 minutes).Conclusion: Intracameral gentamicin was cleared from the anterior chamber after phacoemulsification at a rate that prevents the maintainance of the bactericidal levels required for reliable antibiotic prophylaxis.</div></front></TEI><istex><corpusName>elsevier</corpusName><author><json:item><name>Ordan J. Lehmann FRCOphth</name><affiliations><json:string>The Southampton Eye Unit, England</json:string><json:string>Reprint requests to Ordan J. Lehmann, MD, Department of Ophtbalmology, Salisbury District Hospital, Salisbury Wiltshire SP2 8BJ, England.</json:string></affiliations></json:item><json:item><name>John P. Thompson MRCP</name><affiliations><json:string>Southampton General Hospital, Clinical Pharmacology Group, England</json:string></affiliations></json:item><json:item><name>Les O. White PhD</name><affiliations><json:string>Southampton University, and Bristol Centre for Antimicrobial Research and Evaluation, Southmead Hospital, Bristol, England</json:string></affiliations></json:item><json:item><name>Martin F. Keys FIBMS</name><affiliations><json:string>Public Health Library, England</json:string></affiliations></json:item><json:item><name>Michael J. Campbell PhD</name><affiliations><json:string>Medical Statistics and Computing, England</json:string></affiliations></json:item></author><articleId><json:string>80248</json:string></articleId><language><json:string>eng</json:string></language><abstract>Purpose: To determine the half-life of intracameral gentamicin administered during phacoemulsification.Setting: Southampton Eye Unit, Southampton General Hospital, England.Methods: Thirty-one patients having scleral tunnel phacoemulsification were given intracameral gentamicin in the irrigation fluid. Samples of fluid were taken from the anterior chamber at the end of the operation and at various times postoperatively. The concentration of gentamicin in the samples was determined by fluorescence polarization immunoassay and the half-life calculated for a single compartment model using a peeling algorithm.Results: The concentration of gentamicin in the anterior chamber after phacoemulsification decreased by half every 51 minutes (95% confidence interval, 42 to 66 minutes).Conclusion: Intracameral gentamicin was cleared from the anterior chamber after phacoemulsification at a rate that prevents the maintainance of the bactericidal levels required for reliable antibiotic prophylaxis.</abstract><qualityIndicators><score>6.773</score><pdfVersion>1.7</pdfVersion><pdfPageSize>576 x 828 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>0</keywordCount><abstractCharCount>995</abstractCharCount><pdfWordCount>3249</pdfWordCount><pdfCharCount>21611</pdfCharCount><pdfPageCount>6</pdfPageCount><abstractWordCount>127</abstractWordCount></qualityIndicators><title>Half-life of intracameral gentamicin after phacoemulsification</title><pii><json:string>S0886-3350(97)80248-9</json:string></pii><genre><json:string>research-article</json:string></genre><host><volume>23</volume><pii><json:string>S0886-3350(97)X8223-9</json:string></pii><pages><last>888</last><first>883</first></pages><issn><json:string>0886-3350</json:string></issn><issue>6</issue><genre><json:string>Journal</json:string></genre><language><json:string>unknown</json:string></language><title>Journal of Cataract & Refractive Surgery</title><publicationDate>1997</publicationDate></host><categories><wos><json:string>OPHTHALMOLOGY</json:string><json:string>SURGERY</json:string></wos></categories><publicationDate>1997</publicationDate><copyrightDate>1997</copyrightDate><doi><json:string>10.1016/S0886-3350(97)80248-9</json:string></doi><id>D738A383190636AFF0A4A09DCD91D8AEA4432FBD</id><score>1</score><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/D738A383190636AFF0A4A09DCD91D8AEA4432FBD/fulltext/pdf</uri></json:item><json:item><original>true</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/D738A383190636AFF0A4A09DCD91D8AEA4432FBD/fulltext/txt</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/D738A383190636AFF0A4A09DCD91D8AEA4432FBD/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/D738A383190636AFF0A4A09DCD91D8AEA4432FBD/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Half-life of intracameral gentamicin after phacoemulsification</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>ELSEVIER</p></availability><date>1997</date></publicationStmt><notesStmt><note>Supported by the Sanofi Winthrop Foundation and the Iris Fund for the Prevention of Blindness.</note><note>None of the authors has a financial or proprietary interest in any product mentioned</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Half-life of intracameral gentamicin after phacoemulsification</title><author><persName><forename type="first">Ordan J.</forename><surname>Lehmann</surname></persName><roleName type="degree">FRCOphth</roleName><affiliation>The Southampton Eye Unit, England</affiliation><affiliation>Reprint requests to Ordan J. Lehmann, MD, Department of Ophtbalmology, Salisbury District Hospital, Salisbury Wiltshire SP2 8BJ, England.</affiliation></author><author><persName><forename type="first">John P.</forename><surname>Thompson</surname></persName><roleName type="degree">MRCP</roleName><affiliation>Southampton General Hospital, Clinical Pharmacology Group, England</affiliation></author><author><persName><forename type="first">Les O.</forename><surname>White</surname></persName><roleName type="degree">PhD</roleName><affiliation>Southampton University, and Bristol Centre for Antimicrobial Research and Evaluation, Southmead Hospital, Bristol, England</affiliation></author><author><persName><forename type="first">Martin F.</forename><surname>Keys</surname></persName><roleName type="degree">FIBMS</roleName><affiliation>Public Health Library, England</affiliation></author><author><persName><forename type="first">Michael J.</forename><surname>Campbell</surname></persName><roleName type="degree">PhD</roleName><affiliation>Medical Statistics and Computing, England</affiliation></author></analytic><monogr><title level="j">Journal of Cataract & Refractive Surgery</title><title level="j" type="abbrev">JCRS</title><idno type="pISSN">0886-3350</idno><idno type="PII">S0886-3350(97)X8223-9</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1997"></date><biblScope unit="volume">23</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="883">883</biblScope><biblScope unit="page" to="888">888</biblScope></imprint></monogr><idno type="istex">D738A383190636AFF0A4A09DCD91D8AEA4432FBD</idno><idno type="DOI">10.1016/S0886-3350(97)80248-9</idno><idno type="PII">S0886-3350(97)80248-9</idno><idno type="ArticleID">80248</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1997</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Purpose: To determine the half-life of intracameral gentamicin administered during phacoemulsification.Setting: Southampton Eye Unit, Southampton General Hospital, England.Methods: Thirty-one patients having scleral tunnel phacoemulsification were given intracameral gentamicin in the irrigation fluid. Samples of fluid were taken from the anterior chamber at the end of the operation and at various times postoperatively. The concentration of gentamicin in the samples was determined by fluorescence polarization immunoassay and the half-life calculated for a single compartment model using a peeling algorithm.Results: The concentration of gentamicin in the anterior chamber after phacoemulsification decreased by half every 51 minutes (95% confidence interval, 42 to 66 minutes).Conclusion: Intracameral gentamicin was cleared from the anterior chamber after phacoemulsification at a rate that prevents the maintainance of the bactericidal levels required for reliable antibiotic prophylaxis.</p></abstract></profileDesc><revisionDesc><change when="1997">Published</change></revisionDesc></teiHeader></istex:fulltextTEI></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier doc found" wicri:toSee="Elsevier, no converted or simple article"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" </istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 5.2.0//EN//XML" URI="art520.dtd" name="istex:docType"></istex:docType><istex:document><article version="5.2" xml:lang="en" docsubtype="fla"><item-info><jid>JCRS</jid><aid>80248</aid><ce:pii>S0886-3350(97)80248-9</ce:pii><ce:doi>10.1016/S0886-3350(97)80248-9</ce:doi><ce:copyright type="society" year="1997">American Society of Cataract and Refractive Surgery and European Society of Cataract and Refractive Surgeons. All rights reserved</ce:copyright><ce:copyright-line>Copyright 1997 American Society of Cataract and Refractive Surgery and European Society of Cataract and Refractive Surgeons. All rights reserved</ce:copyright-line></item-info><head><ce:article-footnote><ce:note-para id="ntp005">Supported by the Sanofi Winthrop Foundation and the Iris Fund for the Prevention of Blindness.</ce:note-para></ce:article-footnote><ce:article-footnote><ce:note-para id="ntp010">None of the authors has a financial or proprietary interest in any product mentioned</ce:note-para></ce:article-footnote><ce:title id="ttl005">Half-life of intracameral gentamicin after phacoemulsification</ce:title><ce:author-group id="AUG005"><ce:author id="AUT005"><ce:given-name>Ordan J.</ce:given-name><ce:surname>Lehmann</ce:surname><ce:degrees>FRCOphth</ce:degrees><ce:cross-ref id="crr005" refid="aff1"><ce:sup>1</ce:sup></ce:cross-ref><ce:cross-ref id="crr010" refid="cor1"><ce:sup>*</ce:sup></ce:cross-ref></ce:author><ce:author id="AUT010"><ce:given-name>John P.</ce:given-name><ce:surname>Thompson</ce:surname><ce:degrees>MRCP</ce:degrees><ce:cross-ref id="crr015" refid="aff3"><ce:sup>3</ce:sup></ce:cross-ref></ce:author><ce:author id="AUT015"><ce:given-name>Les O.</ce:given-name><ce:surname>White</ce:surname><ce:degrees>PhD</ce:degrees><ce:cross-ref id="crr020" refid="aff5"><ce:sup>5</ce:sup></ce:cross-ref></ce:author><ce:author id="AUT020"><ce:given-name>Martin F.</ce:given-name><ce:surname>Keys</ce:surname><ce:degrees>FIBMS</ce:degrees><ce:cross-ref id="crr025" refid="aff2"><ce:sup>2</ce:sup></ce:cross-ref></ce:author><ce:author id="AUT025"><ce:given-name>Michael J.</ce:given-name><ce:surname>Campbell</ce:surname><ce:degrees>PhD</ce:degrees><ce:cross-ref id="crr030" refid="aff4"><ce:sup>4</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="aff1"><ce:label>1</ce:label><ce:textfn>The Southampton Eye Unit, England</ce:textfn><sa:affiliation><sa:organization>The Southampton Eye Unit</sa:organization><sa:country>England</sa:country></sa:affiliation></ce:affiliation><ce:affiliation id="aff2"><ce:label>2</ce:label><ce:textfn>Public Health Library, England</ce:textfn><sa:affiliation><sa:address-line>Public Health Library</sa:address-line><sa:country>England</sa:country></sa:affiliation></ce:affiliation><ce:affiliation id="aff3"><ce:label>3</ce:label><ce:textfn>Southampton General Hospital, Clinical Pharmacology Group, England</ce:textfn><sa:affiliation><sa:address-line>Southampton General Hospital, Clinical Pharmacology Group</sa:address-line><sa:country>England</sa:country></sa:affiliation></ce:affiliation><ce:affiliation id="aff4"><ce:label>4</ce:label><ce:textfn>Medical Statistics and Computing, England</ce:textfn><sa:affiliation><sa:address-line>Medical Statistics and Computing</sa:address-line><sa:country>England</sa:country></sa:affiliation></ce:affiliation><ce:affiliation id="aff5"><ce:label>5</ce:label><ce:textfn>Southampton University, and Bristol Centre for Antimicrobial Research and Evaluation, Southmead Hospital, Bristol, England</ce:textfn><sa:affiliation><sa:address-line>Southampton University, and Bristol Centre for Antimicrobial Research and Evaluation, Southmead Hospital</sa:address-line><sa:city>Bristol</sa:city><sa:country>England</sa:country></sa:affiliation></ce:affiliation><ce:correspondence id="cor1"><ce:label>*</ce:label><ce:text>Reprint requests to Ordan J. Lehmann, MD, Department of Ophtbalmology, Salisbury District Hospital, Salisbury Wiltshire SP2 8BJ, England.</ce:text></ce:correspondence></ce:author-group><ce:abstract id="ab1"><ce:section-title id="SET005">Abstract</ce:section-title><ce:abstract-sec id="abs005"><ce:simple-para id="SP0005"><ce:bold>Purpose:</ce:bold> To determine the half-life of intracameral gentamicin administered during phacoemulsification.</ce:simple-para><ce:simple-para id="SP0010"><ce:bold>Setting:</ce:bold> Southampton Eye Unit, Southampton General Hospital, England.</ce:simple-para><ce:simple-para id="SP0015"><ce:bold>Methods:</ce:bold> Thirty-one patients having scleral tunnel phacoemulsification were given intracameral gentamicin in the irrigation fluid. Samples of fluid were taken from the anterior chamber at the end of the operation and at various times postoperatively. The concentration of gentamicin in the samples was determined by fluorescence polarization immunoassay and the half-life calculated for a single compartment model using a peeling algorithm.</ce:simple-para><ce:simple-para id="SP0020"><ce:bold>Results:</ce:bold> The concentration of gentamicin in the anterior chamber after phacoemulsification decreased by half every 51 minutes (95% confidence interval, 42 to 66 minutes).</ce:simple-para><ce:simple-para id="SP0025"><ce:bold>Conclusion:</ce:bold> Intracameral gentamicin was cleared from the anterior chamber after phacoemulsification at a rate that prevents the maintainance of the bactericidal levels required for reliable antibiotic prophylaxis.</ce:simple-para></ce:abstract-sec></ce:abstract></head><tail><ce:bibliography id="R0005"><ce:section-title id="SET010">References</ce:section-title><ce:bibliography-sec id="RS0005"><ce:bib-reference id="bib1"><ce:label>1.</ce:label><sb:reference id="SB0005"><sb:contribution><sb:authors><sb:author><ce:given-name>A</ce:given-name><ce:surname>Fisch</ce:surname></sb:author><sb:author><ce:given-name>A</ce:given-name><ce:surname>Salvanet</ce:surname></sb:author><sb:author><ce:given-name>T</ce:given-name><ce:surname>Prazuck</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Epidemiology of infective endophthalmitis in France; 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Lehmann, MD, Department of Ophtbalmology, Salisbury District Hospital, Salisbury Wiltshire SP2 8BJ, England.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">John P.</namePart><namePart type="family">Thompson</namePart><namePart type="termsOfAddress">MRCP</namePart><affiliation>Southampton General Hospital, Clinical Pharmacology Group, England</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Les O.</namePart><namePart type="family">White</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Southampton University, and Bristol Centre for Antimicrobial Research and Evaluation, Southmead Hospital, Bristol, England</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Martin F.</namePart><namePart type="family">Keys</namePart><namePart type="termsOfAddress">FIBMS</namePart><affiliation>Public Health Library, England</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Michael J.</namePart><namePart type="family">Campbell</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Medical Statistics and Computing, England</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1997</dateIssued><copyrightDate encoding="w3cdtf">1997</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Purpose: To determine the half-life of intracameral gentamicin administered during phacoemulsification.Setting: Southampton Eye Unit, Southampton General Hospital, England.Methods: Thirty-one patients having scleral tunnel phacoemulsification were given intracameral gentamicin in the irrigation fluid. Samples of fluid were taken from the anterior chamber at the end of the operation and at various times postoperatively. The concentration of gentamicin in the samples was determined by fluorescence polarization immunoassay and the half-life calculated for a single compartment model using a peeling algorithm.Results: The concentration of gentamicin in the anterior chamber after phacoemulsification decreased by half every 51 minutes (95% confidence interval, 42 to 66 minutes).Conclusion: Intracameral gentamicin was cleared from the anterior chamber after phacoemulsification at a rate that prevents the maintainance of the bactericidal levels required for reliable antibiotic prophylaxis.</abstract><note>Supported by the Sanofi Winthrop Foundation and the Iris Fund for the Prevention of Blindness.</note><note>None of the authors has a financial or proprietary interest in any product mentioned</note><relatedItem type="host"><titleInfo><title>Journal of Cataract & Refractive Surgery</title></titleInfo><titleInfo type="abbreviated"><title>JCRS</title></titleInfo><genre type="Journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">199707</dateIssued></originInfo><identifier type="ISSN">0886-3350</identifier><identifier type="PII">S0886-3350(97)X8223-9</identifier><part><detail type="volume"><number>23</number><caption>vol.</caption></detail><detail type="issue"><number>6</number><caption>no.</caption></detail><extent unit="issue pages"><start>811</start><end>962</end></extent><extent unit="pages"><start>883</start><end>888</end></extent></part></relatedItem><identifier type="istex">D738A383190636AFF0A4A09DCD91D8AEA4432FBD</identifier><identifier type="DOI">10.1016/S0886-3350(97)80248-9</identifier><identifier type="PII">S0886-3350(97)80248-9</identifier><identifier type="ArticleID">80248</identifier><accessCondition type="use and reproduction" contentType="">© 1997American Society of Cataract and Refractive Surgery and European Society of Cataract and Refractive Surgeons. All rights reserved</accessCondition><recordInfo><recordContentSource>ELSEVIER</recordContentSource><recordOrigin>American Society of Cataract and Refractive Surgery and European Society of Cataract and Refractive Surgeons. All rights reserved, ©1997</recordOrigin></recordInfo></mods></metadata><enrichments><istex:catWosTEI uri="https://api.istex.fr/document/D738A383190636AFF0A4A09DCD91D8AEA4432FBD/enrichments/catWos"><teiHeader><profileDesc><textClass><classCode scheme="WOS">OPHTHALMOLOGY</classCode><classCode scheme="WOS">SURGERY</classCode></textClass></profileDesc></teiHeader></istex:catWosTEI></enrichments><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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