Effect of intraocular lens design on migration of lens epithelial cells onto the posterior capsule
Identifieur interne : 004471 ( Istex/Corpus ); précédent : 004470; suivant : 004472Effect of intraocular lens design on migration of lens epithelial cells onto the posterior capsule
Auteurs : Toshiyuki Nagamoto ; Goro EguchiSource :
- Journal of Cataract & Refractive Surgery [ 0886-3350 ] ; 1997.
Abstract
Purpose: To find the conditions that prevent posterior capsule opacification through in vitro analysis of the relationship between intraocular lens (IOL) optic configuration and lens epithelial cell (LEC) migration.Setting: Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.Methods: In a preliminary experiment, we measured the size of the capsular bag of rabbits at 8, 16, 20, and 26 weeks of age. The size of a 20-week-old capsular bag was the same size as the capsular bag in senescent Japanese eyes. We isolated the capsular bags in 20- and 8-week-old rabbits. The bags along with a biconvex (BC), convex-piano (CP), or no IOL (C) were cultured, and the eyes were divided into one of six groups (8W-C, 8W-BC, 8W-CP, 20W-C, 20W-BC and 20W-CP), each including six specimens.Results: Two specimens in the 8W-CP group completely blocked LEC migration at the optic edge. All specimens in the 20W-CP group and one in the 20W-BC group showed cell aggregation along the optic edge. None of the other specimens in the BC and C groups blocked migration or showed cell aggregation.Conclusions: In the rabbit-model study, the convex-piano lens was superior to the biconvex lens in inhibiting migration of LECs. A firm contact between the IOL and the posterior capsule blocked the migration.
Url:
DOI: 10.1016/S0886-3350(97)80245-3
Links to Exploration step
ISTEX:A82554856E6F0027967563A79C57E5683FC045FFLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effect of intraocular lens design on migration of lens epithelial cells onto the posterior capsule</title><author><name sortKey="Nagamoto, Toshiyuki" sort="Nagamoto, Toshiyuki" uniqKey="Nagamoto T" first="Toshiyuki" last="Nagamoto">Toshiyuki Nagamoto</name><affiliation><mods:affiliation>The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic BiologyOkazakiJapan</mods:affiliation></affiliation></author><author><name sortKey="Eguchi, Goro" sort="Eguchi, Goro" uniqKey="Eguchi G" first="Goro" last="Eguchi">Goro Eguchi</name><affiliation><mods:affiliation>The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic BiologyOkazakiJapan</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:A82554856E6F0027967563A79C57E5683FC045FF</idno><date when="1997" year="1997">1997</date><idno type="doi">10.1016/S0886-3350(97)80245-3</idno><idno type="url">https://api.istex.fr/document/A82554856E6F0027967563A79C57E5683FC045FF/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">004471</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Effect of intraocular lens design on migration of lens epithelial cells onto the posterior capsule</title><author><name sortKey="Nagamoto, Toshiyuki" sort="Nagamoto, Toshiyuki" uniqKey="Nagamoto T" first="Toshiyuki" last="Nagamoto">Toshiyuki Nagamoto</name><affiliation><mods:affiliation>The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic BiologyOkazakiJapan</mods:affiliation></affiliation></author><author><name sortKey="Eguchi, Goro" sort="Eguchi, Goro" uniqKey="Eguchi G" first="Goro" last="Eguchi">Goro Eguchi</name><affiliation><mods:affiliation>The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic BiologyOkazakiJapan</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Cataract & Refractive Surgery</title><title level="j" type="abbrev">JCRS</title><idno type="ISSN">0886-3350</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1997">1997</date><biblScope unit="volume">23</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="866">866</biblScope><biblScope unit="page" to="872">872</biblScope></imprint><idno type="ISSN">0886-3350</idno></series><idno type="istex">A82554856E6F0027967563A79C57E5683FC045FF</idno><idno type="DOI">10.1016/S0886-3350(97)80245-3</idno><idno type="PII">S0886-3350(97)80245-3</idno><idno type="ArticleID">80245</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0886-3350</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Purpose: To find the conditions that prevent posterior capsule opacification through in vitro analysis of the relationship between intraocular lens (IOL) optic configuration and lens epithelial cell (LEC) migration.Setting: Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.Methods: In a preliminary experiment, we measured the size of the capsular bag of rabbits at 8, 16, 20, and 26 weeks of age. The size of a 20-week-old capsular bag was the same size as the capsular bag in senescent Japanese eyes. We isolated the capsular bags in 20- and 8-week-old rabbits. The bags along with a biconvex (BC), convex-piano (CP), or no IOL (C) were cultured, and the eyes were divided into one of six groups (8W-C, 8W-BC, 8W-CP, 20W-C, 20W-BC and 20W-CP), each including six specimens.Results: Two specimens in the 8W-CP group completely blocked LEC migration at the optic edge. All specimens in the 20W-CP group and one in the 20W-BC group showed cell aggregation along the optic edge. None of the other specimens in the BC and C groups blocked migration or showed cell aggregation.Conclusions: In the rabbit-model study, the convex-piano lens was superior to the biconvex lens in inhibiting migration of LECs. A firm contact between the IOL and the posterior capsule blocked the migration.</div></front></TEI><istex><corpusName>elsevier</corpusName><author><json:item><name>Toshiyuki Nagamoto MD, PhD</name><affiliations><json:string>The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic BiologyOkazakiJapan</json:string></affiliations></json:item><json:item><name>Goro Eguchi DSci</name><affiliations><json:string>The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic BiologyOkazakiJapan</json:string></affiliations></json:item></author><articleId><json:string>80245</json:string></articleId><language><json:string>eng</json:string></language><abstract>Purpose: To find the conditions that prevent posterior capsule opacification through in vitro analysis of the relationship between intraocular lens (IOL) optic configuration and lens epithelial cell (LEC) migration.Setting: Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.Methods: In a preliminary experiment, we measured the size of the capsular bag of rabbits at 8, 16, 20, and 26 weeks of age. The size of a 20-week-old capsular bag was the same size as the capsular bag in senescent Japanese eyes. We isolated the capsular bags in 20- and 8-week-old rabbits. The bags along with a biconvex (BC), convex-piano (CP), or no IOL (C) were cultured, and the eyes were divided into one of six groups (8W-C, 8W-BC, 8W-CP, 20W-C, 20W-BC and 20W-CP), each including six specimens.Results: Two specimens in the 8W-CP group completely blocked LEC migration at the optic edge. All specimens in the 20W-CP group and one in the 20W-BC group showed cell aggregation along the optic edge. None of the other specimens in the BC and C groups blocked migration or showed cell aggregation.Conclusions: In the rabbit-model study, the convex-piano lens was superior to the biconvex lens in inhibiting migration of LECs. A firm contact between the IOL and the posterior capsule blocked the migration.</abstract><qualityIndicators><score>7.038</score><pdfVersion>1.7</pdfVersion><pdfPageSize>576 x 828 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>0</keywordCount><abstractCharCount>1349</abstractCharCount><pdfWordCount>2494</pdfWordCount><pdfCharCount>15339</pdfCharCount><pdfPageCount>7</pdfPageCount><abstractWordCount>212</abstractWordCount></qualityIndicators><title>Effect of intraocular lens design on migration of lens epithelial cells onto the posterior capsule</title><pii><json:string>S0886-3350(97)80245-3</json:string></pii><genre><json:string>research-article</json:string></genre><host><volume>23</volume><pii><json:string>S0886-3350(97)X8223-9</json:string></pii><pages><last>872</last><first>866</first></pages><issn><json:string>0886-3350</json:string></issn><issue>6</issue><genre><json:string>Journal</json:string></genre><language><json:string>unknown</json:string></language><title>Journal of Cataract & Refractive Surgery</title><publicationDate>1997</publicationDate></host><categories><wos><json:string>OPHTHALMOLOGY</json:string><json:string>SURGERY</json:string></wos></categories><publicationDate>1997</publicationDate><copyrightDate>1997</copyrightDate><doi><json:string>10.1016/S0886-3350(97)80245-3</json:string></doi><id>A82554856E6F0027967563A79C57E5683FC045FF</id><score>1</score><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/A82554856E6F0027967563A79C57E5683FC045FF/fulltext/pdf</uri></json:item><json:item><original>true</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/A82554856E6F0027967563A79C57E5683FC045FF/fulltext/txt</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/A82554856E6F0027967563A79C57E5683FC045FF/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/A82554856E6F0027967563A79C57E5683FC045FF/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Effect of intraocular lens design on migration of lens epithelial cells onto the posterior capsule</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>ELSEVIER</p></availability><date>1997</date></publicationStmt><notesStmt><note>Neither of the authors has a proprietary interest in the IOLs used in the study. Dr. Nagamoto has a Japanese patent for the intracapsular ring.</note><note>Menicon Inc. provided the intraocular lenses and Pharmacia Inc., the poly(methyl methacrylate) ring.</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Effect of intraocular lens design on migration of lens epithelial cells onto the posterior capsule</title><author><persName><forename type="first">Toshiyuki</forename><surname>Nagamoto</surname></persName><roleName type="degree">MD, PhD</roleName><note type="biography">Reprint requests to Toshiyuki Nagamoto, MD, PhD, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Campus Box 8096 660 South Euclid Avenue, St. Louis, Missouri 63110-1093, USA.</note><affiliation>Reprint requests to Toshiyuki Nagamoto, MD, PhD, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Campus Box 8096 660 South Euclid Avenue, St. Louis, Missouri 63110-1093, USA.</affiliation><affiliation>The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic BiologyOkazakiJapan</affiliation></author><author><persName><forename type="first">Goro</forename><surname>Eguchi</surname></persName><roleName type="degree">DSci</roleName><affiliation>The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic BiologyOkazakiJapan</affiliation></author></analytic><monogr><title level="j">Journal of Cataract & Refractive Surgery</title><title level="j" type="abbrev">JCRS</title><idno type="pISSN">0886-3350</idno><idno type="PII">S0886-3350(97)X8223-9</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1997"></date><biblScope unit="volume">23</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="866">866</biblScope><biblScope unit="page" to="872">872</biblScope></imprint></monogr><idno type="istex">A82554856E6F0027967563A79C57E5683FC045FF</idno><idno type="DOI">10.1016/S0886-3350(97)80245-3</idno><idno type="PII">S0886-3350(97)80245-3</idno><idno type="ArticleID">80245</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1997</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Purpose: To find the conditions that prevent posterior capsule opacification through in vitro analysis of the relationship between intraocular lens (IOL) optic configuration and lens epithelial cell (LEC) migration.Setting: Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.Methods: In a preliminary experiment, we measured the size of the capsular bag of rabbits at 8, 16, 20, and 26 weeks of age. The size of a 20-week-old capsular bag was the same size as the capsular bag in senescent Japanese eyes. We isolated the capsular bags in 20- and 8-week-old rabbits. The bags along with a biconvex (BC), convex-piano (CP), or no IOL (C) were cultured, and the eyes were divided into one of six groups (8W-C, 8W-BC, 8W-CP, 20W-C, 20W-BC and 20W-CP), each including six specimens.Results: Two specimens in the 8W-CP group completely blocked LEC migration at the optic edge. All specimens in the 20W-CP group and one in the 20W-BC group showed cell aggregation along the optic edge. None of the other specimens in the BC and C groups blocked migration or showed cell aggregation.Conclusions: In the rabbit-model study, the convex-piano lens was superior to the biconvex lens in inhibiting migration of LECs. A firm contact between the IOL and the posterior capsule blocked the migration.</p></abstract></profileDesc><revisionDesc><change when="1997">Published</change></revisionDesc></teiHeader></istex:fulltextTEI></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier doc found" wicri:toSee="Elsevier, no converted or simple article"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" </istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 5.2.0//EN//XML" URI="art520.dtd" name="istex:docType"></istex:docType><istex:document><article version="5.2" xml:lang="en" docsubtype="fla"><item-info><jid>JCRS</jid><aid>80245</aid><ce:pii>S0886-3350(97)80245-3</ce:pii><ce:doi>10.1016/S0886-3350(97)80245-3</ce:doi><ce:copyright type="society" year="1997">American Society of Cataract and Refractive Surgery and European Society of Cataract and Refractive Surgeons. All rights reserved</ce:copyright><ce:copyright-line>Copyright 1997 American Society of Cataract and Refractive Surgery and European Society of Cataract and Refractive Surgeons. All rights reserved</ce:copyright-line></item-info><head><ce:article-footnote><ce:note-para id="ntp005">Neither of the authors has a proprietary interest in the IOLs used in the study. Dr. Nagamoto has a Japanese patent for the intracapsular ring.</ce:note-para></ce:article-footnote><ce:article-footnote><ce:note-para id="ntp010">Menicon Inc. provided the intraocular lenses and Pharmacia Inc., the poly(methyl methacrylate) ring.</ce:note-para></ce:article-footnote><ce:title id="ttl005">Effect of intraocular lens design on migration of lens epithelial cells onto the posterior capsule</ce:title><ce:author-group id="AUG005"><ce:author id="AUT005"><ce:given-name>Toshiyuki</ce:given-name><ce:surname>Nagamoto</ce:surname><ce:degrees>MD, PhD</ce:degrees><ce:cross-ref id="crr005" refid="cor1"><ce:sup>*</ce:sup></ce:cross-ref></ce:author><ce:author id="AUT010"><ce:given-name>Goro</ce:given-name><ce:surname>Eguchi</ce:surname><ce:degrees>DSci</ce:degrees></ce:author><ce:affiliation id="aff1"><ce:textfn>The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.</ce:textfn><sa:affiliation><sa:organization>The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology</sa:organization><sa:city>Okazaki</sa:city><sa:country>Japan</sa:country></sa:affiliation></ce:affiliation><ce:correspondence id="cor1"><ce:label>*</ce:label><ce:text>Reprint requests to Toshiyuki Nagamoto, MD, PhD, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Campus Box 8096 660 South Euclid Avenue, St. Louis, Missouri 63110-1093, USA.</ce:text></ce:correspondence></ce:author-group><ce:abstract id="ab1"><ce:section-title id="SET005">Abstract</ce:section-title><ce:abstract-sec id="abs005"><ce:simple-para id="SP0005"><ce:bold>Purpose:</ce:bold> To find the conditions that prevent posterior capsule opacification through in vitro analysis of the relationship between intraocular lens (IOL) optic configuration and lens epithelial cell (LEC) migration.</ce:simple-para><ce:simple-para id="SP0010"><ce:bold>Setting:</ce:bold> Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.</ce:simple-para><ce:simple-para id="SP0015"><ce:bold>Methods:</ce:bold> In a preliminary experiment, we measured the size of the capsular bag of rabbits at 8, 16, 20, and 26 weeks of age. The size of a 20-week-old capsular bag was the same size as the capsular bag in senescent Japanese eyes. We isolated the capsular bags in 20- and 8-week-old rabbits. The bags along with a biconvex (BC), convex-piano (CP), or no IOL (C) were cultured, and the eyes were divided into one of six groups (8W-C, 8W-BC, 8W-CP, 20W-C, 20W-BC and 20W-CP), each including six specimens.</ce:simple-para><ce:simple-para id="SP0020"><ce:bold>Results:</ce:bold> Two specimens in the 8W-CP group completely blocked LEC migration at the optic edge. All specimens in the 20W-CP group and one in the 20W-BC group showed cell aggregation along the optic edge. None of the other specimens in the BC and C groups blocked migration or showed cell aggregation.</ce:simple-para><ce:simple-para id="SP0025"><ce:bold>Conclusions:</ce:bold> In the rabbit-model study, the convex-piano lens was superior to the biconvex lens in inhibiting migration of LECs. A firm contact between the IOL and the posterior capsule blocked the migration.</ce:simple-para></ce:abstract-sec></ce:abstract></head><tail><ce:bibliography id="R0005"><ce:section-title id="SET010">References</ce:section-title><ce:bibliography-sec id="RS0005"><ce:bib-reference id="bib1"><ce:label>1.</ce:label><sb:reference id="SB0005"><sb:contribution><sb:authors><sb:author><ce:given-name>RL</ce:given-name><ce:surname>Lindstrom</ce:surname></sb:author><sb:author><ce:given-name>WS</ce:given-name><ce:surname>Harris</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Management of the posterior capsule following posterior chamber lens implantation</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Am Intra-Ocular Implant Soc J</sb:maintitle></sb:title><sb:volume-nr>6</sb:volume-nr></sb:series><sb:date>1980</sb:date></sb:issue><sb:pages><sb:first-page>255</sb:first-page><sb:last-page>258</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib2"><ce:label>2.</ce:label><sb:reference id="SB0010"><sb:contribution><sb:authors><sb:author><ce:given-name>RM</ce:given-name><ce:surname>Sinskey</ce:surname></sb:author><sb:author><ce:given-name>W</ce:given-name><ce:surname>Cain</ce:surname><ce:suffix>Jr</ce:suffix></sb:author></sb:authors><sb:title><sb:maintitle>The posterior capsule and phacoemulsification</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Am Intra-Ocular Implant Soc J</sb:maintitle></sb:title><sb:volume-nr>4</sb:volume-nr></sb:series><sb:date>1978</sb:date></sb:issue><sb:pages><sb:first-page>206</sb:first-page><sb:last-page>207</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib3"><ce:label>3.</ce:label><sb:reference id="SB0015"><sb:contribution><sb:authors><sb:author><ce:given-name>CD</ce:given-name><ce:surname>Binkhorst</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Five hundred planned extracapsular extractions with irido-capsular and iris clip lens implantation in senile cataract</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Ophthalmic Surg</sb:maintitle></sb:title><sb:volume-nr>8</sb:volume-nr></sb:series><sb:issue-nr>3</sb:issue-nr><sb:date>1977</sb:date></sb:issue><sb:pages><sb:first-page>37</sb:first-page><sb:last-page>44</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib4"><ce:label>4.</ce:label><sb:reference id="SB0020"><sb:contribution><sb:authors><sb:author><ce:given-name>KR</ce:given-name><ce:surname>Wilhelmus</ce:surname></sb:author><sb:author><ce:given-name>JM</ce:given-name><ce:surname>Emery</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Posterior capsule opacification following phacoemulsification</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Ophthalmic Surg</sb:maintitle></sb:title><sb:volume-nr>11</sb:volume-nr></sb:series><sb:date>1980</sb:date></sb:issue><sb:pages><sb:first-page>264</sb:first-page><sb:last-page>267</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib5"><ce:label>5.</ce:label><sb:reference id="SB0025"><sb:contribution><sb:authors><sb:author><ce:given-name>O</ce:given-name><ce:surname>Nishi</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Incidence of posterior capsule opacification in eyes with and without posterior chamber intraocular lenses</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>12</sb:volume-nr></sb:series><sb:date>1986</sb:date></sb:issue><sb:pages><sb:first-page>519</sb:first-page><sb:last-page>522</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib6"><ce:label>6.</ce:label><sb:reference id="SB0030"><sb:contribution><sb:authors><sb:author><ce:given-name>S</ce:given-name><ce:surname>Sterling</ce:surname></sb:author><sb:author><ce:given-name>TO</ce:given-name><ce:surname>Wood</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Effect of intraocular lens convexity on posterior capsule opacification</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>12</sb:volume-nr></sb:series><sb:date>1986</sb:date></sb:issue><sb:pages><sb:first-page>655</sb:first-page><sb:last-page>657</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib7"><ce:label>7.</ce:label><sb:reference id="SB0035"><sb:contribution><sb:authors><sb:author><ce:given-name>TR</ce:given-name><ce:surname>Sellman</ce:surname></sb:author><sb:author><ce:given-name>RL</ce:given-name><ce:surname>Lindstrom</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Effect of a plano-convex posterior chamber lens on capsular opacification from Elschnig pearl formation</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>14</sb:volume-nr></sb:series><sb:date>1988</sb:date></sb:issue><sb:pages><sb:first-page>68</sb:first-page><sb:last-page>72</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib8"><ce:label>8.</ce:label><sb:reference id="SB0040"><sb:contribution><sb:authors><sb:author><ce:given-name>SS</ce:given-name><ce:surname>Setty</ce:surname></sb:author><sb:author><ce:given-name>SPB</ce:given-name><ce:surname>Percival</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Implant design and other factors affecting the need for secondary capsulotomy</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Eur J Implant Refract Surg</sb:maintitle></sb:title><sb:volume-nr>1</sb:volume-nr></sb:series><sb:date>1989</sb:date></sb:issue><sb:pages><sb:first-page>265</sb:first-page><sb:last-page>269</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib9"><ce:label>9.</ce:label><sb:reference id="SB0045"><sb:contribution><sb:authors><sb:author><ce:given-name>CP</ce:given-name><ce:surname>Born</ce:surname></sb:author><sb:author><ce:given-name>DK</ce:given-name><ce:surname>Ryan</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Effect of intraocular lens optic design on posterior capsular opacification</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>16</sb:volume-nr></sb:series><sb:date>1990</sb:date></sb:issue><sb:pages><sb:first-page>188</sb:first-page><sb:last-page>192</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib10"><ce:label>10.</ce:label><sb:reference id="SB0050"><sb:contribution><sb:authors><sb:author><ce:given-name>K</ce:given-name><ce:surname>Yamada</ce:surname></sb:author><sb:author><ce:given-name>T</ce:given-name><ce:surname>Nagamoto</ce:surname></sb:author><sb:author><ce:given-name>H</ce:given-name><ce:surname>Yozawa</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Effect of intraocular lens design on posterior capsule opacification after continuous curvilinear capsulorhexis</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>21</sb:volume-nr></sb:series><sb:date>1995</sb:date></sb:issue><sb:pages><sb:first-page>697</sb:first-page><sb:last-page>700</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib11"><ce:label>11.</ce:label><sb:reference id="SB0055"><sb:contribution><sb:authors><sb:author><ce:given-name>N</ce:given-name><ce:surname>Kyu</ce:surname></sb:author><sb:author><ce:given-name>J</ce:given-name><ce:surname>Suzuki</ce:surname></sb:author><sb:author><ce:given-name>A</ce:given-name><ce:surname>Morimoto</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Capsular bag size</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Jpn Soc Ophthalmic Surg</sb:maintitle></sb:title><sb:volume-nr>4</sb:volume-nr></sb:series><sb:date>1991</sb:date></sb:issue><sb:pages><sb:first-page>457</sb:first-page><sb:last-page>460</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib12"><ce:label>12.</ce:label><sb:reference id="SB0060"><sb:contribution><sb:authors><sb:author><ce:given-name>A</ce:given-name><ce:surname>Galand</ce:surname></sb:author><sb:author><ce:given-name>L</ce:given-name><ce:surname>Bonhomme</ce:surname></sb:author><sb:author><ce:given-name>M</ce:given-name><ce:surname>Collee</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Direct measurement of the capsular bag</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Am Intra-Ocular Implant Soc J</sb:maintitle></sb:title><sb:volume-nr>10</sb:volume-nr></sb:series><sb:date>1984</sb:date></sb:issue><sb:pages><sb:first-page>475</sb:first-page><sb:last-page>476</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib13"><ce:label>13.</ce:label><sb:reference id="SB0065"><sb:contribution><sb:authors><sb:author><ce:given-name>T</ce:given-name><ce:surname>Nagamoto</ce:surname></sb:author><sb:author><ce:given-name>H</ce:given-name><ce:surname>Bissen-Miyajima</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>A ring to support the capsular bag after continuous curvilinear capsulorhexis</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>20</sb:volume-nr></sb:series><sb:date>1994</sb:date></sb:issue><sb:pages><sb:first-page>417</sb:first-page><sb:last-page>420</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib14"><ce:label>14.</ce:label><sb:reference id="SB0070"><sb:contribution><sb:authors><sb:author><ce:given-name>SO</ce:given-name><ce:surname>Hansen</ce:surname></sb:author><sb:author><ce:given-name>KD</ce:given-name><ce:surname>Solomon</ce:surname></sb:author><sb:author><ce:given-name>GT</ce:given-name><ce:surname>McKnight</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Posterior capsular opacification and intraocular decentration. Part I: comparison of various posterior chamber lens de signs implanted in the rabbit model</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>14</sb:volume-nr></sb:series><sb:date>1988</sb:date></sb:issue><sb:pages><sb:first-page>605</sb:first-page><sb:last-page>613</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib15"><ce:label>15.</ce:label><sb:reference id="SB0075"><sb:contribution><sb:authors><sb:author><ce:given-name>MR</ce:given-name><ce:surname>Tetz</ce:surname></sb:author><sb:author><ce:given-name>DJC</ce:given-name><ce:surname>O'Morchoe</ce:surname></sb:author><sb:author><ce:given-name>TD</ce:given-name><ce:surname>Gwin</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Posterior capsular opacification and intraocular decentration. Part II: experimental findings on a prototype circular intraoc ular lens design</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>14</sb:volume-nr></sb:series><sb:date>1988</sb:date></sb:issue><sb:pages><sb:first-page>614</sb:first-page><sb:last-page>623</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib16"><ce:label>16.</ce:label><sb:reference id="SB0080"><sb:contribution><sb:authors><sb:author><ce:given-name>BA</ce:given-name><ce:surname>Santos</ce:surname></sb:author><sb:author><ce:given-name>MA</ce:given-name><ce:surname>DelMonte</ce:surname></sb:author><sb:author><ce:given-name>R</ce:given-name><ce:surname>Pastora</ce:surname></sb:author><sb:author><ce:given-name>FE</ce:given-name><ce:surname>O'Donnell</ce:surname><ce:suffix>Jr</ce:suffix></sb:author></sb:authors><sb:title><sb:maintitle>Lens epithelial inhibition by PMMA optic: implication for lens design</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>12</sb:volume-nr></sb:series><sb:date>1986</sb:date></sb:issue><sb:pages><sb:first-page>23</sb:first-page><sb:last-page>26</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib17"><ce:label>17.</ce:label><sb:reference id="SB0085"><sb:contribution><sb:authors><sb:author><ce:given-name>BA</ce:given-name><ce:surname>Santos</ce:surname></sb:author><sb:author><ce:given-name>MA</ce:given-name><ce:surname>DelMonte</ce:surname></sb:author><sb:author><ce:given-name>R</ce:given-name><ce:surname>Pastora</ce:surname></sb:author><sb:author><ce:given-name>FE</ce:given-name><ce:surname>O'Donnell</ce:surname><ce:suffix>Jr</ce:suffix></sb:author></sb:authors><sb:title><sb:maintitle>Comparative study of the effects of optic design on lens epithelium in vitro</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>13</sb:volume-nr></sb:series><sb:date>1987</sb:date></sb:issue><sb:pages><sb:first-page>127</sb:first-page><sb:last-page>130</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib18"><ce:label>18.</ce:label><sb:reference id="SB0090"><sb:contribution><sb:authors><sb:author><ce:given-name>RG</ce:given-name><ce:surname>Martin</ce:surname></sb:author><sb:author><ce:given-name>DR</ce:given-name><ce:surname>Sanders</ce:surname></sb:author><sb:author><ce:given-name>J</ce:given-name><ce:surname>Souchek</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Effect of posterior chamber intraocular lens design and surgical placement on postoperative outcome</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>18</sb:volume-nr></sb:series><sb:date>1992</sb:date></sb:issue><sb:pages><sb:first-page>333</sb:first-page><sb:last-page>341</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib19"><ce:label>19.</ce:label><sb:reference id="SB0095"><sb:contribution><sb:authors><sb:author><ce:given-name>FP</ce:given-name><ce:surname>Gunning</ce:surname></sb:author><sb:author><ce:given-name>EL</ce:given-name><ce:surname>Greve</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Early posterior capsular opacification after intercapsular cataract extraction and rigid Galand disc intraocular lens implantation</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>18</sb:volume-nr></sb:series><sb:date>1992</sb:date></sb:issue><sb:pages><sb:first-page>366</sb:first-page><sb:last-page>369</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib20"><ce:label>20.</ce:label><sb:reference id="SB0100"><sb:contribution><sb:authors><sb:author><ce:given-name>GJW</ce:given-name><ce:surname>Duncker</ce:surname></sb:author><sb:author><ce:given-name>S</ce:given-name><ce:surname>Westphalen</ce:surname></sb:author><sb:author><ce:given-name>S</ce:given-name><ce:surname>Behrendt</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Complications of silicone disc intraocular lenses</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>21</sb:volume-nr></sb:series><sb:date>1995</sb:date></sb:issue><sb:pages><sb:first-page>562</sb:first-page><sb:last-page>566</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib21"><ce:label>21.</ce:label><sb:reference id="SB0105"><sb:contribution><sb:authors><sb:author><ce:given-name>N</ce:given-name><ce:surname>Mamalis</ce:surname></sb:author><sb:author><ce:given-name>AS</ce:given-name><ce:surname>Crandall</ce:surname></sb:author><sb:author><ce:given-name>E</ce:given-name><ce:surname>Linebarger</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Effect of intraocular lens size on posterior capsule opacification after phacoemulsification</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Cataract Refract Surg</sb:maintitle></sb:title><sb:volume-nr>21</sb:volume-nr></sb:series><sb:date>1995</sb:date></sb:issue><sb:pages><sb:first-page>99</sb:first-page><sb:last-page>102</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference></ce:bibliography-sec></ce:bibliography></tail></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Effect of intraocular lens design on migration of lens epithelial cells onto the posterior capsule</title></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>Effect of intraocular lens design on migration of lens epithelial cells onto the posterior capsule</title></titleInfo><name type="personal"><namePart type="given">Toshiyuki</namePart><namePart type="family">Nagamoto</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic BiologyOkazakiJapan</affiliation><description>Reprint requests to Toshiyuki Nagamoto, MD, PhD, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Campus Box 8096 660 South Euclid Avenue, St. Louis, Missouri 63110-1093, USA.</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Goro</namePart><namePart type="family">Eguchi</namePart><namePart type="termsOfAddress">DSci</namePart><affiliation>The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.The Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic BiologyOkazakiJapan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1997</dateIssued><copyrightDate encoding="w3cdtf">1997</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Purpose: To find the conditions that prevent posterior capsule opacification through in vitro analysis of the relationship between intraocular lens (IOL) optic configuration and lens epithelial cell (LEC) migration.Setting: Division of Morphogenesis, Department of Developmental Biology, National Institute for Basic Biology, Okazaki, Japan.Methods: In a preliminary experiment, we measured the size of the capsular bag of rabbits at 8, 16, 20, and 26 weeks of age. The size of a 20-week-old capsular bag was the same size as the capsular bag in senescent Japanese eyes. We isolated the capsular bags in 20- and 8-week-old rabbits. The bags along with a biconvex (BC), convex-piano (CP), or no IOL (C) were cultured, and the eyes were divided into one of six groups (8W-C, 8W-BC, 8W-CP, 20W-C, 20W-BC and 20W-CP), each including six specimens.Results: Two specimens in the 8W-CP group completely blocked LEC migration at the optic edge. All specimens in the 20W-CP group and one in the 20W-BC group showed cell aggregation along the optic edge. None of the other specimens in the BC and C groups blocked migration or showed cell aggregation.Conclusions: In the rabbit-model study, the convex-piano lens was superior to the biconvex lens in inhibiting migration of LECs. A firm contact between the IOL and the posterior capsule blocked the migration.</abstract><note>Neither of the authors has a proprietary interest in the IOLs used in the study. Dr. Nagamoto has a Japanese patent for the intracapsular ring.</note><note>Menicon Inc. provided the intraocular lenses and Pharmacia Inc., the poly(methyl methacrylate) ring.</note><relatedItem type="host"><titleInfo><title>Journal of Cataract & Refractive Surgery</title></titleInfo><titleInfo type="abbreviated"><title>JCRS</title></titleInfo><genre type="Journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">199707</dateIssued></originInfo><identifier type="ISSN">0886-3350</identifier><identifier type="PII">S0886-3350(97)X8223-9</identifier><part><detail type="volume"><number>23</number><caption>vol.</caption></detail><detail type="issue"><number>6</number><caption>no.</caption></detail><extent unit="issue pages"><start>811</start><end>962</end></extent><extent unit="pages"><start>866</start><end>872</end></extent></part></relatedItem><identifier type="istex">A82554856E6F0027967563A79C57E5683FC045FF</identifier><identifier type="DOI">10.1016/S0886-3350(97)80245-3</identifier><identifier type="PII">S0886-3350(97)80245-3</identifier><identifier type="ArticleID">80245</identifier><accessCondition type="use and reproduction" contentType="">© 1997American Society of Cataract and Refractive Surgery and European Society of Cataract and Refractive Surgeons. All rights reserved</accessCondition><recordInfo><recordContentSource>ELSEVIER</recordContentSource><recordOrigin>American Society of Cataract and Refractive Surgery and European Society of Cataract and Refractive Surgeons. All rights reserved, ©1997</recordOrigin></recordInfo></mods></metadata><enrichments><istex:catWosTEI uri="https://api.istex.fr/document/A82554856E6F0027967563A79C57E5683FC045FF/enrichments/catWos"><teiHeader><profileDesc><textClass><classCode scheme="WOS">OPHTHALMOLOGY</classCode><classCode scheme="WOS">SURGERY</classCode></textClass></profileDesc></teiHeader></istex:catWosTEI></enrichments><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004471 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 004471 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= HapticV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:A82554856E6F0027967563A79C57E5683FC045FF
|texte= Effect of intraocular lens design on migration of lens epithelial cells onto the posterior capsule
}}
| This area was generated with Dilib version V0.6.23. |  |