TocilizumabV1, France, Analysis, indexHead, AbsEn.i

Index : AbsEn.i

Les termes de plus forte occurence

336	patients
289	arthritis
246	rheumatoid
240	disease
234	tocilizumab
198	treatment
185	study
157	title
156	clinical
136	anti
126	sec
123	therapy
108	response
107	inflammatory
107	cell
107	associated
105	efficacy
100	systemic
99	these
99	therapeutic
96	review
92	were
90	safety
88	effects
86	treated
84	drugs
83	results
83	interleukin
82	diseases
80	receptor
78	cells
76	tnf
76	but
72	studies
72	may
71	also
70	data
69	effect
68	management
68	activity
67	patient
67	factor
66	other
66	biological
66	after
64	antibody
63	background
62	role
61	agents
60	new
59	risk
59	factors
58	well
58	severe
57	modifying
57	inflammation
57	first
56	abatacept
55	italic
54	rituximab
54	methotrexate
54	literature
54	antibodies
54	analysis
53	during
53	drug
52	report
52	remission
52	immune
52	development
52	chronic
51	including
51	however
51	all
50	tcz
50	syndrome
50	increased
49	objective
49	active
48	years
48	treatments
48	evidence
47	biologic
46	related
46	onset
46	necrosis
46	monoclonal
46	induced
46	cytokine
46	case
46	autoimmune
45	reported
45	recent
45	objectives
45	high
45	both
44	specific
44	effective
43	who
43	still
43	potential
43	assess
42	trial
42	rheumatic
42	pathogenesis
42	early
42	cases
41	trials
41	therapies
41	levels
41	idiopathic
41	human
40	phase
40	par
40	evaluate
40	could
40	activation
39	refractory
39	controlled
39	compared
38	term
38	several
38	low
38	current
37	than
37	months
37	european
37	against
36	tumor
36	there
36	systematic
36	non
36	long
36	life
36	different
36	conventional
35	most
35	joint
35	antirheumatic
35	aimed
34	practice
34	inhibitors
34	inadequate
34	expression
34	aim
34	abstract
33	type
33	targeted
33	protein
33	key
33	juvenile
33	involved
33	common
33	adult
32	significant
32	large
32	dose
32	cohort
32	biologics
32	assessed
31	year
31	target
31	over
31	important
31	here
31	characterized
31	arteritis
30	through
30	present
30	mechanisms
30	diagnosis
30	describe
30	cytokines
30	combination
30	cancer
29	sclerosis
29	rheumatology
29	recommendations
29	provide
29	available
28	thus
28	targeting
28	inhibitor
28	function
28	control
27	understanding
27	targets
27	rare
27	prospective
27	possible
27	mediated
27	infection
27	impact
27	immunosuppressive
27	french
27	biotherapies
27	approach
26	treat
26	tissue
26	shown
26	progression
26	involvement
26	introduction
26	infliximab
26	effectiveness
26	bone
26	acute
25	various
25	under
25	three
25	side
25	score
25	pathway
25	outcome
25	improvement
25	group
25	damage
25	criteria
25	adalimumab
24	versus
24	strategies
24	significantly
24	responses
24	production
24	primary
24	population
24	only
24	observed
24	moderate
24	major
24	identified
24	had
24	eular
24	due
24	demonstrated
24	considered
24	assessment
24	adverse
23	time
23	those
23	symptoms
23	subcutaneous
23	should
23	regulatory
23	real
23	rate
23	profile
23	outcomes
23	need
23	markers
23	many
23	main
23	international
23	increase
23	included
23	improve
23	giant
23	findings
23	children
23	cardiovascular
23	blood
22	while
22	showed
22	randomized
22	promising
22	novel
22	models
22	higher
22	future
22	further
22	care
22	association
21	therefore
21	synthetic
21	strategy
21	polymyalgia
21	monotherapy
21	manifestations
21	mainly
21	macrophage
21	leading
21	investigate
21	health
21	following
21	events
21	complications
21	better
21	before
21	because
20	will
20	whether
20	sup
20	serum
20	serious
20	rheumatica
20	retrospective
20	randomised
20	pathways
20	often
20	mtx
20	methods
20	infections
20	identify
20	follow
20	failure
20	evaluated
20	dmards
20	approved
20	alpha
19	within
19	weeks
19	unknown
19	tumour
19	tolerance
19	sustained
19	since
19	respectively
19	reduced
19	potentially
19	placebo
19	pathophysiology
19	open
19	number
19	needed
19	level
19	intravenous
19	frequency
19	few
19	especially
19	each
19	disorders
19	defined
19	currently
19	changes
19	blockade
19	biomarkers
19	baseline
19	any
19	alternative
19	addition
18	without
18	when
18	vasculitis
18	second
18	rheumatism
18	recently
18	receiving
18	reactive
18	published
18	observational
18	knowledge
18	inhibition
18	induce
18	index
18	fri
18	established
18	developed
18	dependent
18	corticosteroids
18	controls
18	conclusion
18	action
18	according
17	week
17	vitro
17	survival
17	status
17	similar
17	registry
17	proteins
17	predictive
17	plus
17	ongoing
17	model
17	line
17	known
17	joints
17	information
17	good
17	glucocorticoids
17	evaluation
17	discuss
17	determine
17	benefit
17	being
17	anakinra
17	although
17	adults
16	widely
16	vascular
16	remain
16	relapsing
16	provides
16	part
16	overall
16	order
16	multicenter
16	moreover
16	molecular
16	league
16	label
16	humanized
16	found
16	every
16	condition
16	college
16	cellular
16	body
16	blocking
16	american
16	advances
16	able
15	world
15	vivo
15	very
15	useful
15	update
15	thu
15	system
15	show
15	severity
15	setting
15	rapid
15	pulmonary
15	proinflammatory
15	post
15	performed
15	particularly
15	mass
15	like
15	kinase
15	improved
15	highly
15	fever
15	features
15	experimental
15	etanercept
15	described
15	decreased
15	characteristics
15	bdmards
15	articular
15	another
15	age
15	acr
14	virus
14	structural
14	series
14	research
14	reports
14	renal
14	remains
14	provided
14	proposed
14	pro
14	particular
14	now
14	mice
14	meta
14	measured
14	lung
14	limited
14	least
14	last
14	investigated
14	infusion
14	influence
14	infectious
14	help
14	healthy
14	growth
14	functions
14	four
14	finally
14	dmard
14	discussed
14	despite
14	derived
14	decrease
14	das
14	course
14	corticosteroid
14	context
14	combined
14	cause
14	blockers
14	article
13	wide
13	transplantation
13	subjects
13	sparing
13	signaling
13	short
13	secondary
13	relevant
13	relationship
13	receptors
13	reactions
13	purpose
13	presence

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Index : AbsEn.i

Les termes de plus forte occurence

Manipulations en shell (Unix/Dilib)

Serveur d'exploration Tocilizumab - Analysis (France)

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